Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(165 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8597 produtos de "Metabolismo"
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Theodrenaline hydrochloride
CAS:<p>Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.</p>Fórmula:C17H22ClN5O5Pureza:98% - 98.18%Cor e Forma:SoildPeso molecular:411.84α-Muricholic acid
CAS:<p>α-Muricholic acid is the most abundant primary bile acid in rodents.</p>Fórmula:C24H40O5Pureza:98%Cor e Forma:SolidPeso molecular:408.57PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
CAS:<p>PIP3, a minor yet critical phospholipid for cell signaling, resists PLC cleavage and anchors PH domain proteins, affecting cytoskeletal and membrane dynamics.</p>Fórmula:C21H45NO22P4Cor e Forma:SolidPeso molecular:787.471(±)18-HETE
CAS:<p>(±)18-HETE (18-Hydroxyeicosatetraenoic acid) is an arachidonic acid metabolite with a hydroxyl group on carbon 18, catalyzed by cytochrome P-450.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47tetranor-PGAM
CAS:<p>PGE2 is a biomarker for inflammation and disease; its unstable urinary metabolite, tetranor-PGEM, and its byproduct, tetranor-PGAM, indicate biosynthesis.</p>Fórmula:C16H22O6Cor e Forma:SolidPeso molecular:310.346Sucunamostat hydrochloride
<p>Sucunamostat (SCO-792) hydrochloride is an orally active, reversible inhibitor of enteropeptidase, displaying inhibition constants (IC50) of 4.6 nM for rat</p>Fórmula:C22H23ClN4O8Pureza:98%Cor e Forma:SolidPeso molecular:506.89Cortisol sulfate
CAS:<p>Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol . Cortisol sulfate is a specific ligand for intracellular transcortin [1] [2] [3] .</p>Fórmula:C21H30O8SCor e Forma:SolidPeso molecular:442.52Adrenergic Receptor-Targeted Compound Library
<p>A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;</p>Cor e Forma:Odour SolidAM6701
CAS:<p>AM6701 is a novel highly potent inhibitor of human alpha/beta hydrolase domain 6 (habhd6)</p>Fórmula:C17H17N5OPureza:99.25%Cor e Forma:SolidPeso molecular:307.357Isobutyl Butyrate
CAS:<p>Isobutyl Butyrate is a butyrate ester formed by the condensation of butyric acid with isobutyl alcohol, which is a metabolite of rifampicin.</p>Fórmula:C8H16O2Pureza:99.58%Cor e Forma:SolidPeso molecular:144.21α-2-3,6-sialidase (BiNanH2)
<p>Alpha-2-3,6-sialidase (BiNanH2) is a sialyltransferase for biochemical studies, transferring sialic acid to galactosides.</p>Cor e Forma:SolidN4-Acetylcytidine triphosphate sodium
CAS:<p>N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.</p>Fórmula:C11H18N3Na4O15P3Pureza:98%Cor e Forma:SolidPeso molecular:617.15tetranor-12(S)-HETE
CAS:<p>12(S)-HETE, from arachidonic acid via 12-lipoxygenase, is found in platelets and leukocytes, aids tumor cell adhesion, with a derivative used in research.</p>Fórmula:C16H26O3Cor e Forma:SolidPeso molecular:266.381DSPE-PEG2000-pPB
<p>DSPE-PEG2000-pPB is a PEG compound comprised of DSPE and the cyclic oligopeptide (pPB). The pPB component exhibits a high binding affinity for PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB is utilizable for drug delivery applications.</p>Cor e Forma:Odour SolidAvellanin B
CAS:<p>Avellanin B is a fungal metabolite.</p>Fórmula:C30H37N5O5Cor e Forma:SolidPeso molecular:547.656Lurasidone metabolite 14326
CAS:<p>Lurasidone metabolite 14326, an active metabolite of the atypical antipsychotic Lurasidone, functions effectively in the body.</p>Fórmula:C28H36N4O3SPureza:98%Cor e Forma:SolidPeso molecular:508.68Prostaglandin F2β
CAS:<p>Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α.</p>Fórmula:C20H34O5Cor e Forma:White SolidPeso molecular:354.48Urate oxidase
CAS:<p>Uricase catalyzes uric acid to allantoin in many mammals' peroxisomes, used in biochemistry.</p>Cor e Forma:Solidα-Pyrone
CAS:<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Fórmula:C5H4O2Cor e Forma:SolidPeso molecular:96.08Glucose 1-dehydrogenase
CAS:<p>Glucose 1-dehydrogenase, an enzyme, transforms glucose and NAD(P) into NAD(P)H and gluconic acid.</p>Cor e Forma:Solid(2-Hydroxyethoxy)acetic acid
CAS:<p>'(2-Hydroxyethoxy)acetic acid is 1,4-Dioxane's primary urine metabolite and a reliable short-term biomarker.'</p>Fórmula:C4H8O4Cor e Forma:SolidPeso molecular:120.1hCAIX-IN-17
<p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>Fórmula:C19H18N2O3SCor e Forma:SolidPeso molecular:354.422-Hydroxy atorvastatin lactone
CAS:<p>2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].</p>Fórmula:C33H33FN2O5Cor e Forma:SolidPeso molecular:556.62O-Demethyl Lenvatinib
CAS:<p>O-Demethyl Lenvatinib, a Lenvatinib metabolite, is an oral TKI targeting VEGFR, FGFR, PDGFR, KIT & RET with potent antitumor effects.</p>Fórmula:C20H17ClN4O4Cor e Forma:SolidPeso molecular:412.83Atorvastatin Epoxy Tetrahydrofuran Impurity
CAS:<p>Atorvastatin Epoxy Tetrahydrofuran: an impurity from Atorvastatin oxidation; it's an oral HMG-CoA reductase inhibitor.</p>Fórmula:C26H24FNO5Pureza:98%Cor e Forma:SolidPeso molecular:449.47D-Fructose-13C6
CAS:<p>D-Fructose-13C6 can be used as an internal standard for the quantification of D-fructose by GC- or LC-MS.</p>Fórmula:C6H12O6Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:186.11O-desmethyl Mebeverine acid
CAS:<p>O-desmethyl Mebeverine acid is a metabolite of Mebeverine.</p>Fórmula:C15H23NO3Pureza:98%Cor e Forma:SolidPeso molecular:265.35DSPE-PEG2000-CREKA
<p>DSPE-PEG3000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide targets tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3000-CREKA is useful in drug delivery applications.</p>Cor e Forma:Odour SolidCAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Fórmula:C15H17N3O4SPureza:99.07%Cor e Forma:SolidPeso molecular:335.38H-Tyr-Ala-OH
CAS:<p>Tyrosylalanine (H-Tyr-Ala-OH), a dipeptide comprising L-tyrosine and L-alanine, is referenced in studies [1] [2].</p>Fórmula:C12H16N2O4Pureza:99.74%Cor e Forma:SolidPeso molecular:252.27Cholesteryl Homo-γ-Linolenate
CAS:<p>Cholesteryl homo-γ-linolenate is a cholesterol ester.</p>Fórmula:C47H78O2Cor e Forma:SolidPeso molecular:675.139Orotidine 5′-monophosphate
CAS:<p>Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E.</p>Fórmula:C10H13N2O11PCor e Forma:SolidPeso molecular:368.191Autophagy inducer 5
<p>Autophagyinducer 5 (compound 21o) serves as a potent inhibitor of MCF-7 (IC50: 2 μM), making it a potential candidate for breast cancer therapy. It induces autophagy by activating the ROS/JNK signaling pathway, which increases ROS production and JNK phosphorylation, ultimately exerting cytotoxic effects.</p>Fórmula:C41H52N4O3Cor e Forma:SolidPeso molecular:648.88RMC-4630
CAS:<p>RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.</p>Fórmula:C20H27ClN6O2SPureza:99.07% - 99.65%Cor e Forma:SolidPeso molecular:450.99SGK1-IN-3 hydrochloride
<p>SGK1-IN-3 hydrochloride (compound 3a) is an efficacious, orally bioavailable SGK1 inhibitor. The serine/threonine kinase SGK1 acts as an activator of the β-catenin pathway and strongly stimulates cartilage degradation, being upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride holds potential for osteoarthritis research.</p>Fórmula:C23H21Cl3N6O3SPeso molecular:566.04614Fluazifop-P-butyl
CAS:<p>Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].</p>Fórmula:C19H20F3NO4Cor e Forma:Light Yellow LiquidPeso molecular:383.36Diadenosine pentaphosphate pentaammonium
CAS:<p>Endogenous vasoactive dinucleotide isolated from thrombocytes; found in secretory vesicles across various cells.</p>Fórmula:C20H44N15O22P5Cor e Forma:SolidPeso molecular:1001.524Cy3 IRGD-PEG-DSPE
<p>Cy3 IRGD-PEG-DSPE is a PEG phospholipid containing Cy3 dye, applicable for protein/nucleic acid labeling and fluorescence microscopy. It self-assembles in aqueous solutions to form micelles or lipid bilayers, which are useful for creating liposomes or nanoparticles for the delivery of nutrients, such as mRNA or DNA vaccines.</p>Cor e Forma:Odour SolidSMS2-IN-1
CAS:<p>SMS2-IN-1: potent SMS2 inhibitor; IC50: 6.5 nM, Kd: 37 nM; 150x selectivity over SMS1.</p>Fórmula:C34H37F6N3O5Pureza:98%Cor e Forma:SolidPeso molecular:681.67Di-O-demethylcurcumin
CAS:<p>Di-O-demethylcurcumin (Bisdemethylcurcumin) is an intestinal metabolite of curcumin known for its neuroprotective properties.</p>Fórmula:C19H16O6Cor e Forma:SolidPeso molecular:340.33DSPE-PEG2000-LTLRWVGLMS
<p>DSPE-PEG2000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). Chondroitin sulfate proteoglycan NG2 is the receptor for LLRWVGLMS. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG2000-LTLRWVGLMS can be utilized for drug delivery.</p>Cor e Forma:Odour SolidTriethyl phosphate
CAS:<p>Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".</p>Fórmula:C6H15O4PPureza:98%Cor e Forma:Clear LiquidPeso molecular:182.16(Rac)-5-Keto Fluvastatin
CAS:<p>(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.</p>Fórmula:C24H24FNO4Pureza:95.04%Cor e Forma:SolidPeso molecular:409.45FUT8-IN-1
<p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>Fórmula:C23H25ClN2OCor e Forma:SolidPeso molecular:380.91BBOX-IN-1
<p>BBOX-IN-1 (compound 58) is a potent BBOX inhibitor with an IC50 of 0.02 μM, and it is applicable in research related to triple-negative breast cancer (TNBC).</p>Fórmula:C18H17N3O6SCor e Forma:SolidPeso molecular:403.41N-Trifluoroacetyladriamycin
CAS:<p>N-Trifluoroacetyladriamycin, Valrubicin's metabolite, treats bladder cancer; it's an analog of doxorubicin, infused into the bladder.</p>Fórmula:C29H28F3NO12Cor e Forma:SolidPeso molecular:639.533IP3RPEP6
CAS:<p>IP3RPEP6 serves as a competitive inhibitor of IP3R. Its IC50 values for IP3R1, IP3R2, and IP3R3 are 9.0 μM, 3.9 μM, and 4.3 μM, respectively. This compound does not affect ryanodine receptors and Cx43 hemichannels, and it is capable of modulating intracellular calcium signaling.</p>Fórmula:C49H79N15O24Cor e Forma:SolidPeso molecular:1262.24Tetrachlorocatechol
CAS:<p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>Fórmula:C6H2Cl4O2Pureza:96.68%Cor e Forma:SolidPeso molecular:247.89FASN-IN-4 tosylate
CAS:<p>FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.</p>Fórmula:C33H35N3O7S2Cor e Forma:SolidPeso molecular:649.78Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Cor e Forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72
