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Metabolismo

Metabolismo

Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.

Subcategorias de "Metabolismo"

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Foram encontrados 8626 produtos de "Metabolismo"

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  • ND-011992

    CAS:
    <p>ND-011992: Quinazoline inhibitor of E. coli respiratory enzymes; IC50s: 0.12-2.47 μM; potential tuberculosis research.</p>
    Fórmula:C21H14F3N3O
    Pureza:99.7%
    Cor e Forma:Soild
    Peso molecular:381.35
  • Paeoniflorgenin

    CAS:
    <p>Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin[1].</p>
    Fórmula:C17H18O6
    Cor e Forma:Solid
    Peso molecular:318.325
  • Laccase-IN-1


    <p>Laccase-IN-1 (compound 4b) is an orally active laccase inhibitor, demonstrating an IC50 of 11.3 μM.</p>
    Fórmula:C16H19FN2O3
    Cor e Forma:Solid
    Peso molecular:306.33
  • 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv

    CAS:
    <p>2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole derivative is a potent, lung-selective anti-inflammatory in Sprague Dawley rats.</p>
    Fórmula:C25H34F2O6
    Pureza:98.20%
    Cor e Forma:Soild
    Peso molecular:468.53
  • Myristelaidic Acid

    CAS:
    <p>Myristelaidic Acid is a natural product for research related to life sciences. The catalog number is T37358 and the CAS number is 50286-30-1.</p>
    Fórmula:C14H26O2
    Cor e Forma:Solid
    Peso molecular:226.35
  • MAHMA NONOate

    CAS:
    <p>MAHMA NONOate is a pH-dependent NO donor.MAHMA NONOate inhibits collagen or ADP-induced platelet aggregation.</p>
    Fórmula:C8H20N4O2
    Pureza:≥98%
    Cor e Forma:Solid
    Peso molecular:204.27
  • Oleic Acid-2,6-diisopropylanilide

    CAS:
    <p>Oleic acid-2,6-diisopropylanilide: ACAT inhibitor, IC50 7 nM; lowers LDL &amp; raises HDL in high-fat fed rabbits/rats at 0.05%.</p>
    Fórmula:C30H51NO
    Cor e Forma:Solid
    Peso molecular:441.744
  • CUDA

    CAS:
    <p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>
    Fórmula:C19H36N2O3
    Pureza:97.585%
    Cor e Forma:Solid
    Peso molecular:340.5
  • Carbonic anhydrase inhibitor 26


    <p>Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.</p>
    Fórmula:C17H14N6O4
    Cor e Forma:Solid
    Peso molecular:366.33
  • Glutarylcarnitine lithium


    <p>Glutarylcarnitine lithium indicates malonic aciduria, glutaric aciduria I in newborn screenings.</p>
    Fórmula:C12H20LiNO6
    Cor e Forma:Solid
    Peso molecular:281.23
  • iso-C15:0 3-OH

    CAS:
    <p>Iso-C15:0 3-OH is a fatty acid that can be isolated from the PLRT strain. PLRT is a rod-shaped, Gram-negative, chemolithoheterotrophic, obligately aerobic bacterium, obtained from the feces of the mollusk Aplysia punctata.</p>
    Fórmula:C15H30O3
    Cor e Forma:Solid
    Peso molecular:258.397
  • 16(R)-HETE

    CAS:
    <p>16(S)-HETE, a CYP450 byproduct of arachidonic acid, halts kidney ATPase by 60% at 2µM when angiotensin II is present.</p>
    Fórmula:C20H32O3
    Cor e Forma:Solid
    Peso molecular:320.473
  • Benzoic acid (Standard)

    CAS:
    <p>Benzoic acid (Standard) is a standard substance for quantitative analysis.Benzoic acid (Dracylic acid) is an aromatic alcohol and common additive.</p>
    Fórmula:C7H6O2
    Pureza:99.99%
    Cor e Forma:White Solid Monoclinic Tablets Plates Leaflets
    Peso molecular:122.12
  • Uricosuric agent-1

    CAS:
    <p>Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]- is a compound used for antiviral activity determinations.</p>
    Fórmula:C19H16O5
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:324.33
  • Ono EI-601

    CAS:
    <p>Ono EI-601 is the main metabolite of ONO-5046, the human neutrophil elastase inhibitor .</p>
    Fórmula:C15H14N2O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:350.35
  • (±)10(11)-DiHDPA

    CAS:
    <p>(±)10(11)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid .</p>
    Fórmula:C22H34O4
    Cor e Forma:Solid
    Peso molecular:362.51
  • 11β-HSD1 inibitor 19

    CAS:
    <p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>
    Fórmula:C19H16ClF4N3O2S
    Pureza:99.58%
    Cor e Forma:Soild
    Peso molecular:461.86
  • Enpp-1-IN-14

    CAS:
    <p>Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.</p>
    Fórmula:C15H22ClN5O4S
    Pureza:99.83%
    Cor e Forma:Soild
    Peso molecular:403.88
  • PF-1355

    CAS:
    <p>PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.</p>
    Fórmula:C14H15N3O4S
    Pureza:99.93%
    Cor e Forma:Solid
    Peso molecular:321.35
  • Compound 48/80 trihydrochloride

    CAS:
    <p>Compound 48/80 trihydrochloride (C48/80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48/80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48/80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。</p>
    Fórmula:C32H48Cl3N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:629.1
  • IR-117-17

    CAS:
    <p>IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.</p>
    Fórmula:C59H110N2O5
    Cor e Forma:Solid
    Peso molecular:927.52
  • Phosphate acetyltransferase

    CAS:
    <p>Phosphate acetyltransferase, an enzyme, reversibly transfers acetyl groups to CoA, aiding in acetate assimilation/dissimilation.</p>
    Cor e Forma:Solid
  • SGK1-IN-3 hydrochloride


    <p>SGK1-IN-3 hydrochloride (compound 3a) is an efficacious, orally bioavailable SGK1 inhibitor. The serine/threonine kinase SGK1 acts as an activator of the β-catenin pathway and strongly stimulates cartilage degradation, being upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride holds potential for osteoarthritis research.</p>
    Fórmula:C23H21Cl3N6O3S
    Peso molecular:566.04614
  • FXR agonist 5

    CAS:
    <p>FXR agonist 5 is an FXR agonist used in the study of liver diseases or diseases mediated by metabolic inflammation.</p>
    Fórmula:C40H53N5O5
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:683.88
  • LOC1886

    CAS:
    <p>LOC1886 is a covalent inhibitor of GPX4, with slightly lower potency compared to RSL3 and ML162.</p>
    Fórmula:C13H11N3O2
    Cor e Forma:Solid
    Peso molecular:241.25
  • DSPE-PEG2000-CGKRK


    <p>DSPE-PEG2000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is suitable for use in drug delivery.</p>
    Cor e Forma:Odour Solid
  • Cirsiliol 4′-glucoside

    CAS:
    <p>Cirsiliol 4′-glucoside, a compound extracted from Ruellia tuberosa L., acts as a free radical scavenger and demonstrates potential anti-diabetic activity [1].</p>
    Fórmula:C23H24O12
    Cor e Forma:Solid
    Peso molecular:492.43
  • 1,2,3,6,7,8-Hexachlorodibenzofuran

    CAS:
    <p>1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.</p>
    Fórmula:C12H2Cl6O
    Cor e Forma:Solid
    Peso molecular:374.86
  • Ionizable Lipid 4

    CAS:
    <p>Ionizable Lipid 4 is an ionizable cationic lipid that forms as a product of the rearrangement of cationic lipid CA-lipid 5 under hydrogen peroxide induction.</p>
    Fórmula:C48H85NO7
    Cor e Forma:Solid
    Peso molecular:788.19
  • Glycogen phosphorylase-IN-2


    <p>Glycogen phosphorylase-IN-2 (compound 9C) is an inhibitor of glycogen phosphorylase, with a Ki value of 1.9 nM and an IC50 value of 4 nM.</p>
    Cor e Forma:Odour Solid
  • (rac./meso)-Astaxanthin

    CAS:
    <p>(rac./meso)-Astaxanthin (AstaREAL; AstaXin) is a carotenoid pigment primarily found in marine animals such as shrimp and salmon. It serves as an effective fat-soluble antioxidant.</p>
    Fórmula:C40H52O4
    Cor e Forma:Solid
    Peso molecular:596.84
  • VU534

    CAS:
    <p>VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related</p>
    Fórmula:C21H22FN3O3S2
    Pureza:98.85%
    Cor e Forma:Solid
    Peso molecular:447.55
  • Diorcinol

    CAS:
    <p>Diorcinol is a natural product that can be used as a reference standard. The CAS number of Diorcinol is 20282-75-1.</p>
    Fórmula:C14H14O3
    Cor e Forma:Solid
    Peso molecular:230.263
  • Kyotorphin

    CAS:
    <p>Kyotorphin is a Morphine-like dipeptide.</p>
    Fórmula:C15H23N5O4
    Cor e Forma:Solid
    Peso molecular:337.38
  • Aculene A

    CAS:
    <p>Aculene A is a unique type of norsesquiterpene from Aspergillus aculeatus [1] .</p>
    Fórmula:C19H25NO3
    Cor e Forma:Solid
    Peso molecular:315.41
  • DCG04

    CAS:
    <p>DCG04: a mannose-6-phosphate receptor ligand, fluorescent cysteine cathepsin probe for endolysosomal targeting.</p>
    Fórmula:C43H66N8O11S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:903.11
  • 2′,3′-Di-O-acetyl-5′-deoxy-5-fluorocytidine

    CAS:
    <p>2'',3''-Di-O-acetyl-5''-deoxy-5-fuluro-D-cytidine is a derivative of capecitabine.</p>
    Fórmula:C13H16FN3O6
    Pureza:99.51%
    Cor e Forma:Solid
    Peso molecular:329.28
  • Coumachlor

    CAS:
    <p>Coumachlor, a first-generation anticoagulant rodenticide, blocks the formation of prothrombin and inhibits blood coagulation causing internal haemorrhage.</p>
    Fórmula:C19H15ClO4
    Cor e Forma:Solid
    Peso molecular:342.77
  • Octachlorodibenzo-p-dioxin

    CAS:
    <p>Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant with no acute toxicity when administered. In rats, the systemic elimination half-life of Octachlorodibenzo-p-dioxin (50 μg/kg intravenously or 50-5000 μg/kg orally) is 3-5 months. It can accumulate and concentrate in the liver and adipose tissue after low-dose, repeated exposure. Repeated dosing of Octachlorodibenzo-p-dioxin leads to increased activity of 7-ethoxyresorufin-O-deethylase (7-EROD) and elevated total cytochrome P-450 levels.</p>
    Fórmula:C12Cl8O2
    Cor e Forma:Solid
    Peso molecular:459.75
  • WWL123

    CAS:
    <p>WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM).</p>
    Fórmula:C28H24N2O3
    Pureza:99.62%
    Cor e Forma:Solid
    Peso molecular:436.5
  • L,L-Dityrosine

    CAS:
    <p>L,L-Dityrosine, a component found in the acid hydrolysates of various biological materials, such as insect cuticular resilin, plays a significant role in</p>
    Fórmula:C18H20N2O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:360.36
  • Betulin ditosylate

    CAS:
    <p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>
    Fórmula:C44H62O6S2
    Cor e Forma:Solid
    Peso molecular:751.09
  • Isariin C

    CAS:
    <p>Isariin C is a flavonoid glucoside derived from the Epimedium plant genus. It stimulates angiogenesis and exhibits antioxidant activity.</p>
    Fórmula:C28H49N5O7
    Cor e Forma:Solid
    Peso molecular:567.72
  • Phenylpyropene A

    CAS:
    <p>Phenylpyropene A, a P. griseofulvum fungus product, blocks ACAT (IC50=0.8μM) and DGAT, kills M. persicae at 5ppm.</p>
    Fórmula:C32H38O10
    Cor e Forma:Solid
    Peso molecular:582.64
  • GQ-16

    CAS:
    <p>GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.</p>
    Fórmula:C19H16BrNO3S
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:418.3
  • Acetate kinase (ACK)

    CAS:
    <p>ACK, found in bacteria/archaea, phosphorylates acetate with ATP and cations, yielding acetyl-CoA; used in biochemistry.</p>
    Cor e Forma:Solid
  • Malonyl CoA

    CAS:
    <p>Malonyl CoA: needed for fat creation, stops fat breakdown, reversibly inhibits CPT1 in mitochondria.</p>
    Fórmula:C24H38N7O19P3S
    Cor e Forma:Solid
    Peso molecular:853.58
  • PKM2 inhibitor G

    CAS:
    <p>PKM2 inhibitor G is a inhibitor of pyruvate kinase.</p>
    Fórmula:C16H15NO3S
    Pureza:99.89%
    Cor e Forma:Soild
    Peso molecular:301.36
  • 5-Methoxyresorcinol

    CAS:
    <p>5-Methoxyresorcinol (Flamenol) is a chemical intermediate.</p>
    Fórmula:C7H8O3
    Pureza:95.16%
    Cor e Forma:Solid
    Peso molecular:140.14
  • Linoleoyl-L-carnitine (chloride)

    CAS:
    <p>Linoleoyl-L-carnitine, a natural acylcarnitine, rises in mouse liver post high-dose isoniazid (200 mg/kg).</p>
    Fórmula:C25H46ClNO4
    Cor e Forma:Solid
    Peso molecular:460.1