Metabolismo

Boc-D-His(trt)-OH is an amino acid derivative and has a wide range of applications in life science related research.

MRS2802 is a P2Y14 receptor agonist, its EC50 value for P2Y14 receptor is 63 nM.

8-Bromo-AMP, also known as 8-Bromoadenosine 5'-monophosphate, is a membrane permeable cAMP analogue. It enhances cardiac recovery from ischemia and reperfusion by elevating ATP, ADP, and total adenine nucleotide concentrations.

Antibiotic K 4 is an inhibitor of angiotensin I converting enzyme produced by Actinomadura spiculosospora.

(S)-3-Hydroxyisobutyric acid is an important interorgan metabolite.

3,5-Dibromotyrosine is a useful organic compound for research related to life sciences. The catalog number is T65914 and the CAS number is 300-38-9.

5-FAM-Alkyne is a highly selective and sensitive fluorescent biosensor designed for detecting alkaline phosphatase (ALP).

LEO-32731 is a bioactive chemical.

Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS) utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.

Valiolamine is a useful organic compound for research related to life sciences. The catalog number is T65494 and the CAS number is 83465-22-9.

<p>Neuraminic acid: acidic amino sugar, 9 carbon chain, from pyruvic acid + D-mannosamine, in active mucoproteins.</p>

DSR-141562 is a new compound that can be taken orally and has a specific ability to inhibit phosphodiesterase 1 (PDE1) in the brain. This compound exhibits a preference for inhibiting human PDE1B, with an IC50 value of 43.9 nM. It also shows moderate inhibition of human PDE1A (IC50 = 97.6 nM) and PDE1C (IC50 = 431.8 nM). DSR-141562 is particularly useful in the study of positive symptoms, negative symptoms, and cognitive impairments associated with schizophrenia.

CGC-11047 free base is a second generation polyamine analogue of N1, N12-bisethylspermine (BESpm).

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran .

<p>Elamipretide TFA (RX-31 TFA) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide[1].</p>

WAY-339495 may have anti-tumor, anti-inflammatory and analgesic activity and can be used to study obesity, cardiovascular disease, diabetes, neurodegenerative diseases, Alzheimer's disease and stroke.

MY33-3 is a powerful and specific inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, demonstrating an IC50 value of approximately 0.1 μM. Moreover, MY33-3 exhibits inhibitory activity against PTP-1B with an IC50 value of about 0.7 μM. Additionally, MY33-3 has been shown to effectively decrease ethanol consumption and alleviate neuroinflammation and cognitive dysfunction induced by Sevoflurane.

(R)-Linezolid, an impurity of Linezolid, inhibits the initiation of bacterial protein synthesis.

Epiquinidine, an analogue of quinine, serves as an agonist for ggTas2r1, exhibiting activation at concentrations of 10 μM or higher.

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to TGF-β1. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for TGF-β1. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain TGF-β1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of TGF-β1. You can calculate the concentration of TGF-β1 in the samples by comparing the OD of the samples to the standard curve.