CAS 42835-25-6: Flumequine
Description:Flumequine is a synthetic fluoroquinolone antibiotic primarily used in veterinary medicine for the treatment of bacterial infections in livestock and aquaculture. It exhibits broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. Flumequine is typically administered orally or via injection, and its pharmacokinetics can vary based on the species treated. The substance is characterized by its relatively low solubility in water, which can influence its bioavailability and distribution in biological systems. Additionally, flumequine has been studied for its potential environmental impact, as residues can persist in animal waste and aquatic environments, raising concerns about antibiotic resistance and ecological effects. Safety assessments indicate that, while effective, flumequine should be used judiciously to minimize the risk of developing resistant bacterial strains. Overall, flumequine serves as an important tool in veterinary medicine, but its use must be managed carefully to ensure both animal health and environmental safety.
Formula:C14H12FNO3
InChI:InChI=1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
InChI key:InChIKey=DPSPPJIUMHPXMA-UHFFFAOYSA-N
SMILES:O=C(O)C1=CN2C=3C(=CC(F)=CC3CCC2C)C1=O
- Synonyms:
- 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-
- 9-Fluoro-6,7-Dihydro-5-Methyl-1-Oxo-1H,5H-Benzo[Ij]Quinolizine-2-Carboxylic Acid
- 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
- Apurone
- Fantacin
- Firestop
- Flumequine solution
- Flumigal
- Flumiquil
- Flumisol
- See more synonyms
- Flumix
- Imequyl
- R 802
- R 802 (bactericide)
- Flumequine