Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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β-Elemonic Acid
CAS:<p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>Formula:C30H46O3Purity:99.61% - 99.8%Color and Shape:SolidMolecular weight:454.68Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Formula:C21H20N4O3Purity:98% - 99.74%Color and Shape:SolidMolecular weight:376.41Ligustilide
CAS:<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Formula:C12H14O2Purity:96.03% - 98.14%Color and Shape:Yellow Brown PowderMolecular weight:190.24Onatasertib
CAS:<p>Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.</p>Formula:C21H27N5O3Purity:99.14% - 99.97%Color and Shape:SolidMolecular weight:397.47JIB-04
CAS:<p>JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor.</p>Formula:C17H13ClN4Purity:98.02% - 98.87%Color and Shape:SolidMolecular weight:308.76Tebufenozide
CAS:<p>Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.</p>Formula:C22H28N2O2Purity:98%Color and Shape:SolidMolecular weight:352.47PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Formula:C16H14BrN5O4S·HClPurity:97.82%Color and Shape:SolidMolecular weight:488.74MFCD01917484
CAS:<p>MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.</p>Formula:C14H15NO3SPurity:98.09%Color and Shape:SolidMolecular weight:277.345-Aminolevulinic acid hydrochloride
CAS:<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Formula:C5H10ClNO3Purity:98% - 99.97%Color and Shape:White To Pale Yellow Crystals OrMolecular weight:167.59Fludarabine Phosphate
CAS:<p>Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.</p>Formula:C10H13FN5O7PPurity:99.25% - 99.78%Color and Shape:SolidMolecular weight:365.21L-Theanine
CAS:<p>L-Theanine, a unique amino acid from Camellia sinensis tea, induces relaxation without drowsiness.</p>Formula:C7H14N2O3Purity:99.31% - 99.38%Color and Shape:White Crystals From Ethanol + Water White Crystalline SolidMolecular weight:174.2Carvacrol
CAS:<p>1.</p>Formula:C10H14OPurity:99.05%Color and Shape:Needles LiquidMolecular weight:150.22Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formula:C21H26N7Na4O17P3Purity:97.15% - >99.99%Color and Shape:SolidMolecular weight:833.35Glaucocalyxin A
CAS:<p>Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.</p>Formula:C20H28O4Purity:99.55% - 99.80%Color and Shape:SolidMolecular weight:332.43Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34Pyroxamide
CAS:<p>Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).</p>Formula:C13H19N3O3Purity:98.46%Color and Shape:SolidMolecular weight:265.31ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Formula:C29H25N3O4SPurity:98.08% - >99.99%Color and Shape:SolidMolecular weight:511.59Pinoresinol
CAS:<p>Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury</p>Formula:C20H22O6Purity:98.67%Color and Shape:SolidMolecular weight:358.391-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Formula:C21H13ClF3N3O2Purity:99.41%Color and Shape:SolidMolecular weight:431.82-Deoxy-D-glucose
CAS:<p>2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis.</p>Formula:C6H12O5Purity:99.31% - ≥98%Color and Shape:White PowderMolecular weight:164.16Supinoxin
CAS:<p>Supinoxin (RX-5902) is an oral anti-cancer drug targeting p68 RNA helicase, inducing apoptosis in TNBC cells (IC50: 10-20nM).</p>Formula:C22H24FN5O4Purity:99.83% - 99.95%Color and Shape:SolidMolecular weight:441.46GDC-0152
CAS:<p>GDC-0152 is a potent inhibitor of IAPs.</p>Formula:C25H34N6O3SPurity:97.18% - 99.32%Color and Shape:SolidMolecular weight:498.64CCT128930 hydrochloride
CAS:<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Formula:C18H21Cl2N5Purity:98.55%Color and Shape:SolidMolecular weight:378.3Lobaplatin
CAS:<p>Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.</p>Formula:C9H18N2O3PtPurity:98.00%Color and Shape:SolidMolecular weight:397.33Elesclomol
CAS:<p>Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier.</p>Formula:C19H20N4O2S2Purity:97.17% - 99.51%Color and Shape:SolidMolecular weight:400.52Rilmenidine Phosphate
CAS:<p>Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.</p>Formula:C10H19N2O5PPurity:99.87% - ≥95%Color and Shape:SolidMolecular weight:278.24Vandetanib
CAS:<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35CP-31398 dihydrochloride
CAS:<p>CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines.</p>Formula:C22H28Cl2N4OPurity:98.23%Color and Shape:SolidMolecular weight:435.4LRRK2-IN-1
CAS:<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Formula:C31H38N8O3Purity:98% - 98.82%Color and Shape:SolidMolecular weight:570.69kauran-16,17-diol
CAS:<p>Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7</p>Formula:C20H34O2Purity:99.93%Color and Shape:SolidMolecular weight:306.48Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14NSC 95397
CAS:<p>NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).</p>Formula:C14H14O4S2Purity:98.66%Color and Shape:SolidMolecular weight:310.39SKI II
CAS:<p>SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.</p>Formula:C15H11ClN2OSPurity:99.34% - 99.93%Color and Shape:SolidMolecular weight:302.78Lorlatinib
CAS:<p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>Formula:C21H19FN6O2Purity:99.77% - 99.95%Color and Shape:SolidMolecular weight:406.41STF-118804
CAS:<p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.</p>Formula:C25H23N3O4SPurity:98.66%Color and Shape:SolidMolecular weight:461.53GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formula:C43H46F3N7O7SPurity:98.78% - >99.99%Color and Shape:SolidMolecular weight:861.932-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formula:C15H12O2Purity:99.6%Color and Shape:SolidMolecular weight:224.25Phellamurin
CAS:<p>Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.</p>Formula:C26H30O11Purity:97.91%Color and Shape:SolidMolecular weight:518.51ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Formula:C22H29ClN4O3Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:432.94Astragalin
CAS:<p>Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.</p>Formula:C21H20O11Purity:98.8% - ≥95%Color and Shape:SolidMolecular weight:448.38ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formula:C42H45ClN6O5S2Purity:98.15% - >99.99%Color and Shape:SolidMolecular weight:813.43R-7050
CAS:<p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>Formula:C16H8ClF3N4SPurity:98.64% - 99.8%Color and Shape:SolidMolecular weight:380.77JX06
CAS:<p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>Formula:C10H16N2O2S4Purity:99.4%Color and Shape:SolidMolecular weight:324.51Etidronic acid
CAS:<p>Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.</p>Formula:C2H8O7P2Purity:99.93% - ≥95%Color and Shape:Liquid SyrupMolecular weight:206.03WYC-209
CAS:<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Formula:C20H20N2O3SPurity:99.77%Color and Shape:SolidMolecular weight:368.45Anisomycin
CAS:<p>Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.</p>Formula:C14H19NO4Purity:98.33% - 99.81%Color and Shape:White Crystalline SolidMolecular weight:265.3BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Formula:C20H18N6O3Purity:98.72%Color and Shape:SolidMolecular weight:390.4Diosgenin glucoside
CAS:<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Formula:C33H52O8Purity:97.17% - 99.44%Color and Shape:SolidMolecular weight:576.76Phenoxodiol
CAS:<p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>Formula:C15H12O3Purity:98.07%Color and Shape:SolidMolecular weight:240.25
