Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6068 products of "Apoptosis"
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Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormula:C21H32O2Purity:99.59% - 99.92%Color and Shape:SolidMolecular weight:316.48Ref: TM-TN1465
1mg145.00€2mg215.00€5mg314.00€10mg474.00€25mg808.00€50mg1,111.00€100mg1,501.00€1mL*10mM (DMSO)324.00€Protosappanin B
CAS:Protosappanin B enhances cell survival, growth protein 43; degrades p53 via MDM2 ubiquitination.Formula:C16H16O6Purity:98% - 98.86%Color and Shape:SolidMolecular weight:304.29Piperacetazine
CAS:Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.Formula:C24H30N2O2SPurity:99.9% - 99.92%Color and Shape:SolidMolecular weight:410.57MK-2206
CAS:MK-2206: selective Akt inhibitor, oral, targets Akt1, Akt2, Akt3; effective in breast cancer, PIK3CA mutants, PTEN-deficient cells.Formula:C25H22ClN5OColor and Shape:SolidMolecular weight:443.94Citric acid monohydrate
CAS:Citric Acid Monohydrate: tricarboxylic, from citrus, antioxidant, stabilizes drugs, preservative.Formula:C6H10O8Purity:99.87%Color and Shape:White Solid CrystallineMolecular weight:210.14(E/Z)-Necrosulfonamide
CAS:(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.Formula:C18H15N5O6S2Purity:97.62% - 98%Color and Shape:SolidMolecular weight:461.47OTS964 hydrochloride
CAS:OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.Formula:C23H24N2O2S·HClPurity:96.5% - 98.03%Color and Shape:SolidMolecular weight:428.97Ref: TM-T4135
1mg46.00€2mg59.00€5mg93.00€10mg124.00€25mg197.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)97.00€PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purity:99.40%Color and Shape:SolidMolecular weight:557.56Ref: TM-T21635
1mg38.00€2mg52.00€5mg79.00€10mg126.00€25mg273.00€50mg454.00€100mg653.00€200mg938.00€500mg1,406.00€Atractylenolide II
CAS:Atractylenolide II inhibits STAT3, activates p38, deactivates ERK/Akt, and induces p53-dependent cytotoxicity against melanoma.Formula:C15H20O2Purity:99.89% - 99.93%Color and Shape:SolidMolecular weight:232.32Ref: TM-T5S0168
1mg39.00€5mg74.00€10mg96.00€25mg156.00€50mg220.00€100mg325.00€200mg472.00€1mL*10mM (DMSO)88.00€RIPGBM
CAS:RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).Formula:C26H21FN2O3Purity:99.45%Color and Shape:SolidMolecular weight:428.45Ref: TM-T16754
2mg38.00€5mg57.00€10mg87.00€25mg187.00€50mg335.00€100mg560.00€200mg715.00€1mL*10mM (DMSO)64.00€Pectolinarin
CAS:Pectolinarin is a Cirsium isolate with anti-inflammatory activity.Formula:C29H34O15Purity:98% - 99.79%Color and Shape:SolidMolecular weight:622.57PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.5Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62Ref: TM-T6311
1mg37.00€2mg52.00€5mg79.00€10mg103.00€25mg159.00€50mg188.00€100mg350.00€200mg455.00€1mL*10mM (DMSO)90.00€PHT-427
CAS:PHT-427 (CS-0223) is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).Formula:C20H31N3O2S2Purity:97.54% - >99.99%Color and Shape:SolidMolecular weight:409.61R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Formula:C18H21F2N5O4SPurity:90% - 99.64%Color and Shape:SolidMolecular weight:441.45Ref: TM-T6312
1mg50.00€5mg101.00€10mg147.00€25mg268.00€50mg515.00€100mg740.00€200mg1,026.00€1mL*10mM (DMSO)120.00€Arctigenin
CAS:(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formula:C21H24O6Purity:98% - 99.51%Color and Shape:SolidMolecular weight:372.41Avadomide
CAS:<p>Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.</p>Formula:C14H14N4O3Purity:99.56%Color and Shape:SolidMolecular weight:286.29PHA-793887
CAS:PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.Formula:C19H31N5O2Purity:98.02% - >99.99%Color and Shape:SolidMolecular weight:361.48Ref: TM-T2113
2mg35.00€5mg52.00€10mg80.00€25mg120.00€50mg195.00€100mg314.00€200mg469.00€1mL*10mM (DMSO)52.00€IITZ-01
CAS:IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Formula:C26H23FN8OPurity:99.31%Color and Shape:SolidMolecular weight:482.51Milademetan free base
CAS:Milademetan (DS-3032b) is a potent MDM2 inhibitor, potentially blocking cancer growth by targeting p53 protein.Formula:C37H42Cl2FN5O7SPurity:98%Color and Shape:SolidMolecular weight:790.73Licochalcone B
CAS:Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.Formula:C16H14O5Purity:99.33% - 99.9%Color and Shape:SolidMolecular weight:286.28Ref: TM-T4S0350
1mg52.00€5mg117.00€10mg188.00€25mg329.00€50mg490.00€100mg710.00€1mL*10mM (DMSO)140.00€PD-1/PD-L1-IN-10
CAS:PD-1/PD-L1-IN-10 is an orally available PD-1/PD-L1 inhibitor (IC50 value of 2.7 nM) that shows anti-tumor activity.Cost-effective and quality-assured.Formula:C33H31N3O7Purity:99.63%Color and Shape:SolidMolecular weight:581.62Omaveloxolone
CAS:Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.Formula:C33H44F2N2O3Purity:98.7% - 99.92%Color and Shape:SolidMolecular weight:554.71Ref: TM-T6919
1mg46.00€2mg59.00€5mg87.00€10mg119.00€25mg210.00€50mg354.00€100mg512.00€500mg1,093.00€1mL*10mM (DMSO)107.00€Panobinostat lactate
CAS:Panobinostat lactate: potent, non-selective, oral HDAC inhibitor; treats refractory multiple myeloma.Formula:C24H29N3O5Color and Shape:SolidMolecular weight:439.512BMS-1
CAS:<p>BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.</p>Formula:C29H33NO5Purity:99.40% - 99.81%Color and Shape:SolidMolecular weight:475.58PF-3758309
CAS:PF-3758309 (PF-03758309) (IC50=1.3 nM), a pyrrolopyrazole inhibitor of PAK4, has effective ATP-competition.Formula:C25H30N8OSPurity:97.70%Color and Shape:SolidMolecular weight:490.62Madecassoside
CAS:Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFormula:C48H78O20Purity:99.46% - 99.85%Color and Shape:White PowderMolecular weight:975.12Ref: TM-T2813
10mg52.00€25mg88.00€50mg127.00€100mg188.00€200mg305.00€500mg512.00€1mL*10mM (DMSO)51.00€SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formula:C24H28Cl2N2O4Purity:99.00% - ≥95%Color and Shape:SolidMolecular weight:479.4Karanjin
CAS:Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.Formula:C18H12O4Purity:99.01%Color and Shape:SolidMolecular weight:292.29Ref: TM-T2S0820
1mg48.00€5mg92.00€10mg154.00€25mg274.00€50mg406.00€100mg588.00€200mg833.00€1mL*10mM (DMSO)To inquireRaddeanin A
CAS:Raddeanin A is a natural triterpenoid saponin from Cyperus japonicus that inhibits histone deacetylase.Cost-effective and quality-assured.Formula:C47H76O16Purity:98% - 99.94%Color and Shape:SolidMolecular weight:897.10Ref: TM-T3878
1mg48.00€5mg87.00€10mg144.00€25mg235.00€50mg349.00€100mg494.00€200mg705.00€1mL*10mM (DMSO)143.00€Liensinine
CAS:1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.Formula:C37H42N2O6Purity:98.92% - 99.93%Color and Shape:White-Like PowderMolecular weight:610.74Jaceosidin
CAS:Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.Formula:C17H14O7Purity:98.23% - 99.28%Color and Shape:SolidMolecular weight:330.29Costunolide
CAS:Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.Formula:C15H20O2Purity:97.19% - >99.99%Color and Shape:SolidMolecular weight:232.32Ref: TM-T2902
2mg35.00€5mg49.00€10mg74.00€25mg119.00€50mg172.00€100mg250.00€200mg371.00€1mL*10mM (DMSO)52.00€Prexasertib dihydrochloride
CAS:Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.Formula:C18H21Cl2N7O2Purity:98.46% - 99.82%Color and Shape:SolidMolecular weight:438.31Ref: TM-T4327
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg274.00€50mg427.00€100mg630.00€500mg1,320.00€1mL*10mM (DMSO)92.00€AP-III-a4
CAS:AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.Formula:C31H43FN8O3Purity:98.24% - 99.90%Color and Shape:SolidMolecular weight:594.72Ref: TM-T6759
1mg51.00€2mg78.00€5mg120.00€10mg188.00€25mg369.00€50mg588.00€100mg938.00€200mg1,378.00€1mL*10mM (DMSO)157.00€KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81Ref: TM-T8756
1mg60.00€2mg86.00€5mg119.00€10mg188.00€25mg354.00€50mg512.00€100mg655.00€1mL*10mM (DMSO)143.00€Pomalidomide
CAS:Pomalidomide (CC-4047) is an anti-angiogenic and immunomodulatory agent. Pomalidomide is a ligand for CRBN. Cost-effective and quality-assured.Formula:C13H11N3O4Purity:98.8% - >99.99%Color and Shape:SolidMolecular weight:273.24Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98.02% - 98.59%Color and Shape:SolidMolecular weight:292.35Ref: TM-T4048
1mg48.00€5mg78.00€10mg97.00€25mg188.00€50mg311.00€100mg502.00€500mg1,074.00€1mL*10mM (DMSO)87.00€MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Formula:C16H13F3N6OPurity:99.76%Color and Shape:SolidMolecular weight:362.31Ref: TM-T33514
1mg84.00€2mg97.00€5mg158.00€10mg240.00€25mg393.00€50mg560.00€100mg753.00€200mg1,035.00€CHS-828
CAS:CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formula:C19H22ClN5OPurity:98% - 99.9%Color and Shape:SolidMolecular weight:371.86Torin 2
CAS:Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.Formula:C24H15F3N4OPurity:98.31% - 99.32%Color and Shape:SolidMolecular weight:432.4NVP-ADW742
CAS:NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-AblFormula:C28H31N5OPurity:96.14% - 98.70%Color and Shape:SolidMolecular weight:453.58LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Ref: TM-T3494
2mg47.00€5mg69.00€10mg89.00€25mg183.00€50mg298.00€100mg449.00€500mg938.00€1mL*10mM (DMSO)69.00€Isosorbide Mononitrate
CAS:Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.Formula:C6H9NO6Purity:98.16%Color and Shape:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMolecular weight:191.14Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurity:99.94%Color and Shape:SolidMolecular weight:653.21iCRT3
CAS:iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.Formula:C23H26N2O2SPurity:98.32% - 98.47%Color and Shape:SolidMolecular weight:394.53Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Formula:C2H7NS·HClPurity:99.34% - 99.87%Color and Shape:White Crystalline Powder With A Strong And Disagreeable SmellMolecular weight:113.61Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Formula:C21H19ClN4O2Purity:93.468% - 99.31%Color and Shape:SolidMolecular weight:394.85Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Formula:C20H21N3O2·HClPurity:97.24% - 99.15%Color and Shape:SolidMolecular weight:371.86
