Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(647 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,025 products)
- BACE(37 products)
- Beta Amyloid(230 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(602 products)
- Dopamine Receptor(445 products)
- GABA Receptor(373 products)
- Gamma-secretase(62 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
Show 12 more subcategories
Found 5639 products of "Neuroscience"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
(S)-4CPG
CAS:(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.Formula:C9H9NO4Purity:99.96%Color and Shape:SolidMolecular weight:195.17EasyStep Human EFNA1(Ephrin A1) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human EFNA1, and the Human EFNA1 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human EFNA1. After TMB substrate solution is added, only those wells that contain Human EFNA1 and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human EFNA1 in the samples is then determined by comparing the OD of the samples to the standard curve.Color and Shape:Colourless TransparentliquidMonepantel
CAS:Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.Formula:C20H13F6N3O2SPurity:99.83%Color and Shape:White PowderMolecular weight:473.39Ref: TM-T16126
1mg93.00€5mg236.00€1mL*10mM (DMSO)259.00€10mg340.00€25mg670.00€50mg964.00€100mg1,378.00€Citalopram-d6
CAS:Controlled ProductApplications Labelled Citalopram (C505000), an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.
References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001),Formula:C202H6H15FN2OColor and Shape:NeatMolecular weight:330.43ACT-462206
CAS:ACT-462206 is a Orexin 1/Orexin 2 receptor antagonist.ACT-462206 is highly potent and can be used to study sleep and anxiety.Formula:C20H24N2O4SPurity:99.45%Color and Shape:SolidMolecular weight:388.48Ref: TM-T26559
1mg42.00€1mL*10mM (DMSO)87.00€5mg88.00€10mg130.00€25mg264.00€50mg423.00€100mg670.00€500mg1,341.00€EasyStep Human PSA(ProstateSpecific Antigen) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PSA, and the Human PSA standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human PSA. After TMB substrate solution is added, only those wells that contain Human PSA and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human PSA in the samples is then determined by comparing the OD of the samples to the standard curve.Color and Shape:Colourless TransparentliquidPipecuronium bromide
CAS:Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.Formula:C35H62Br2N4O4Purity:>99.99%Color and Shape:PowderMolecular weight:762.7Jatrorrhizine chloride
CAS:Jatrorrhizine chloride (Neprotine chloride) is an alkaloid isolated from Rhizoma coptidis with neuroprotective, antimicrobial, and antiplasmodial activities.Formula:C20H20ClNO4Purity:99.79%Color and Shape:SolidMolecular weight:373.8Rizatriptan
CAS:Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.Formula:C15H19N5Purity:99.74%Color and Shape:SolidMolecular weight:269.35EasyStep Human BNP(Brain Natriuretic Peptide) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BNP, and the Human BNP standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human BNP. After TMB substrate solution is added, only those wells that contain Human BNP and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human BNP in the samples is then determined by comparing the OD of the samples to the standard curve.Color and Shape:Colourless TransparentliquidUCM 608
CAS:UCM 608 (2-Phenylmelatonin) is an antagonist of melatonin-induced contractile responses at low concentrations and induces an increase in GDP-GTP exchange.Formula:C19H20N2O2Purity:98.88%Color and Shape:SolidMolecular weight:308.37Citalopram
CAS:Citalopram (Lu 10-171), a serotonin and 5-HT reuptake inhibitor.Citalopram has antidepressant activity and may be used to study dementia.Formula:C20H21FN2OPurity:99.78% - 99.89%Color and Shape:SolidMolecular weight:324.393,4-Dihydroxyphenylacetic Acid-13C,18O2
CAS:Applications A labelled metabolite of Dopamine.
References Johnson, S., et al.: J. Physiol., 450, 455 (1992), Kolesnikov, Y., et al.: Eur. J. Pharmacol., 296, 17 (1996), Leshner, A., et al.: Science, 278, 45 (1997), Li, J., et al.: Acta Pharmacol. Sin., 20, 375 (1999), Gibson, D., et al.: Brain Res., 952, 71 (2002), Volpicelli, L., et al.: Pharmacol. Biochem. Behav., 64, 487 (1999),Wei, X., et al.: Eur. J. Pharmacol., 515, 99 (2005)Formula:C713CH8O218O2Color and Shape:NeatMolecular weight:173.14Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formula:C14H15F3N6OPurity:97.63%Color and Shape:SolidMolecular weight:340.3Donepezil-d5
CAS:Donepezil-d5 is a deuterated compound of Donepezil. Donepezil has a CAS number of 120014-06-4. Donepezil is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type.Formula:C24H24D5NO3Color and Shape:SolidMolecular weight:384.52Fenitrothion-d6 (O,O-dimethyl-d6)
CAS:Fenitrothion-d6 (O,O-dimethyl-d6) is a deuterated compound of Fenitrothion. Fenitrothion has a CAS number of 122-14-5. Fenitrothion is an organothiophosphate cholinesterase inhibitor. Fenitrothion is used as an insecticide.
Formula:C9H6D6NO5PSColor and Shape:SolidMolecular weight:283.27Acephate-d3 (acetyl-d3)
CAS:Acephate-d3 (acetyl-d3) is a deuterated compound of Acephate. Acephate has a CAS number of 30560-19-1. Acephate is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.Formula:C4H7D3NO3PSColor and Shape:SolidMolecular weight:186.18Chlorpyrifos (diethyl-d10)
CAS:Chlorpyrifos (diethyl-d10) is a deuterated compound of Chlorpyrifos. Chlorpyrifos has a CAS number of 2921-88-2. Chlorpyrifos is an organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.Formula:C9H1D10Cl3NO3PSColor and Shape:SolidMolecular weight:360.65Pyridostigmine-d6 bromide
CAS:Pyridostigmine D6 bromide is the deuterium labeled Pyridostigmine, which is a parasympathomimetic and a reversible inhibitor of cholinesterase.Formula:C9H13BrN2O2Purity:98%Color and Shape:SolidMolecular weight:267.15Sulindac EP Impurity C-d3
CAS:Sulindac EP Impurity C-d3 is a deuterated compound of Sulindac EP Impurity C. Sulindac EP Impurity C has a CAS number of 32004-67-4. (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease [1].Formula:C20H14D3FO2SColor and Shape:SolidMolecular weight:343.43Varenicline
CAS:Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26Ref: TM-T4246L
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg75.00€25mg137.00€50mg200.00€100mg313.00€200mg464.00€R 59-022
CAS:R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formula:C27H26FN3OSPurity:98.55%Color and Shape:SolidMolecular weight:459.58Ref: TM-T16709
1mg35.00€5mg74.00€1mL*10mM (DMSO)75.00€10mg119.00€25mg269.00€50mg447.00€100mg733.00€200mg973.00€Cyproheptadine hydrochloride
CAS:Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.Formula:C21H21N·HClPurity:99.88% - 99.97%Color and Shape:SolidMolecular weight:323.86Rocatinlimab
CAS:Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated IgG1 anti-OX40 monoclonal antibody indicated for atopic dermatitis (AD) research [1].Color and Shape:LiquidBChE-IN-25
CAS:BChE-IN-25 (compound 4I) acts as a selective inhibitor of BChE, demonstrating an IC 50 of 3.77μM and exhibiting 22-fold greater selectivity towards BChE over AChE [1].Formula:C17H23NO2Color and Shape:SolidMolecular weight:273.37Benmoxin
CAS:Benmoxin is a monoamine oxidase inhibitor (MAOI) that is irreversible and nonselective.Formula:C15H16N2OPurity:98%Color and Shape:SolidMolecular weight:240.30N-Methyl amisulpride
CAS:N-Methyl amisulpride (Amisulpride impurity H) is a 5-HT7 receptor, D2 receptor, and D3 receptor antagonist used in the study of acute schizophrenia.Formula:C18H29N3O4SColor and Shape:SolidMolecular weight:383.51eeAChE/eqBuChE-IN-1
CAS:eeAChE/eqBuChE-IN-1 (compound 3F) serves as a reversible dual inhibitor of eeAChE/eqBuChE, exhibiting IC50 values of 1.3 μM and 0.81 μM, respectively. In addition, this compound demonstrates anti-inflammatory properties and provides neuroprotective effects against Aβ25-35-induced injury in PC12 cells [1].Formula:C14H16N2O2Color and Shape:SolidMolecular weight:244.29Keto Ziprasidone
CAS:Ziprasidone, an antipsychotic agent, functions as a dual antagonist of 5-HT (serotonin) and dopamine receptors.Formula:C21H19ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:426.92Escitalopram
CAS:Escitalopram (Seroplex), a serotonin inhibitor for depression, curbs alcohol intake and is favored over tricyclics for tardive dyskinesia.Formula:C20H21FN2OPurity:99.82%Color and Shape:White Or White Crystalline PowderMolecular weight:324.39Dilpacimab
CAS:Dilpacimab (ABT165) is a dual-variable antibody that targets DLL4 and VEGF pathways, showing potential in cancer research by blocking angiogenesis and Notch.Purity:95% - 97.7% (SDS-PAGE); 95.6% (SEC-HPLC)Color and Shape:LiquidAChE-IN-65
CAS:AChE-IN-65 (Compound DABA_1) serves as a mixed inhibitor of acetylcholinesterase (AChE), exhibiting a Ki of 556.4 μM against Electrophorus electricus AChE.Formula:C15H8N2O6Color and Shape:SolidMolecular weight:312.23Arazasetron HCl
CAS:Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27.Formula:C17H20ClN3O3Purity:98%Color and Shape:SolidMolecular weight:349.81Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.Formula:C22H28N2O14Purity:98%Color and Shape:SolidMolecular weight:544.46Unasnemab
CAS:Unasnemab (MT-3921) binds RGMa, promoting neuroregeneration and locomotor function, showing potential for spinal cord injury and regenerative research.Purity:95% - 97.4% (SDS-PAGE); 98.3% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.90 kDaRisperidone Mesylate
CAS:Risperidone Mesylate is a selective serotonin 5-HT2 receptor and dopamine D2 receptor blocker.Formula:C24H31FN4O5SPurity:98%Color and Shape:SolidMolecular weight:506.59Atropine hydrobromide
CAS:Atropine hydrobromide is a biochemical.Formula:C17H24BrNO3Color and Shape:SolidMolecular weight:370.28Remternetug
CAS:Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, Alzheimer's disease.Purity:95% - 97.6% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.87 kDaDezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Purity:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.82 kDa(+)-Tomoxetine hydrochloride
CAS:(+)-Tomoxetine hydrochloride is a bioactive chemical.Formula:C17H22ClNOPurity:98%Color and Shape:SolidMolecular weight:291.82Tarextumab
CAS:Tarextumab is an anti-Notch2/3 mAb, a promising candidate for breast, lung, ovarian, and pancreatic cancers.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaMonoamine Oxidase B inhibitor 4
CAS:Monoamine Oxidase B Inhibitor 4 (compound 1l), with a potent IC50 value of 8.3 nM, is a selective human monoamine oxidase-B (hMAO-B) inhibitor. This compound demonstrates anti-neuroinflammatory properties and exhibits low neurotoxicity. It effectively inhibits the release of NO, TNF-α, and IL-1β induced by LPS and Aβ1-42, and additionally mitigates the cytotoxic effects triggered by Aβ(1-42) .Formula:C15H11Cl2NO3Color and Shape:SolidMolecular weight:324.16Bapineuzumab
CAS:Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Purity:95%Color and Shape:LiquidMolecular weight:145.86 kDaSerotonin Creatinine Sulfate Monohydrate
CAS:Formula:C14H19N5O2·H2SO4·H2OPurity:>98.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:405.43Tyrphostin AG 494
CAS:Formula:C16H12N2O3Purity:>98.0%(HPLC)(N)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:280.28KB-R 7943
CAS:Formula:C16H17N3O3S·CH4O3SPurity:>98.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:427.49Tomatine from Tomato
CAS:Formula:C50H83NO21Purity:>80.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:1,034.20Medroxyprogesterone
CAS:Formula:C22H32O3Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:344.50Ruthenium(II) Nitrosyl Chloride
CAS:Formula:RuCl3NOPurity:>97.0%(T)Color and Shape:Yellow to Amber to Dark red powder to crystalMolecular weight:255.45Hyodeoxycholic Acid
CAS:Formula:C24H40O4Purity:>98.0%(T)Color and Shape:White to Orange to Green powder to crystalMolecular weight:392.58Gestrinone
CAS:Formula:C21H24O2Purity:>98.0%(T)Color and Shape:Light yellow to Yellow powder to crystalMolecular weight:308.424,5,6,7-Tetrabromobenzotriazole
CAS:Formula:C6HBr4N3Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:434.71Prostaglandin F2α
CAS:Formula:C20H34O5Purity:>95.0%(T)Color and Shape:White or Colorless to Almost white or Almost colorless powder to lump to clear liquidMolecular weight:354.49Lubiprostone
CAS:Formula:C20H32F2O5Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:390.47Tetrasodium 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetate
CAS:Formula:C22H20N2Na4O10Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:564.37(-)-Deguelin
CAS:Formula:C23H22O6Purity:>95.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:394.42Pipamperone
CAS:Formula:C21H30FN3O2Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:375.491,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt
CAS:Formula:C34H66NaO10PPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:688.86Amitriptyline-d6 Hydrochloride
CAS:Amitriptyline-d6 Hydrochloride is a deuterated compound of Amitriptyline Hydrochloride. Amitriptyline Hydrochloride has a CAS number of 549-18-8. Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.Formula:C20H18D6ClNColor and Shape:SolidMolecular weight:319.90Milnacipran-d10 Hydrochloride
CAS:Milnacipran-d10 Hydrochloride is a deuterated compound of Milnacipran Hydrochloride. Milnacipran Hydrochloride has a CAS number of 101152-94-7. Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Levomilnacipran is an enantiomer of milnacipran, which is used to treat fibromyalgia. Levomilnacipran and milnacipran have been associated with a low rate of transient elevations in serum aminotransferase levels during treatment and with rare instances of clinically apparent acute liver injury with jaundice.Formula:C15H13D10ClN2OColor and Shape:SolidMolecular weight:292.87Brexpiprazole-d8
CAS:Brexpiprazole D8 is a deuterium-modified partial agonist of 5-HT1A and dopamine receptors, with Ki values of 0.12 nM and 0.3 nM respectively.Formula:C25H27N3O2SPurity:98%Color and Shape:SolidMolecular weight:441.62Mirtazapine D3
CAS:Mirtazapine D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .Formula:C17H19N3Purity:98%Color and Shape:SolidMolecular weight:268.37Homotaurine-d6
CAS:Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Formula:C3D6H3NO3SColor and Shape:SolidMolecular weight:145.21Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formula:C3H8O6S2Color and Shape:SolidMolecular weight:204.22VU0477886
CAS:VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.Formula:C20H13ClN4O3Purity:98%Color and Shape:SolidMolecular weight:392.807-Desmethyl-3-hydroxyagomelatine
CAS:7-Desmethyl-3-hydroxyagomelatine, less active than parent drug Agomelatine, is a melatonergic agonist and 5-HT2C antagonist.Formula:C14H15NO3Purity:98%Color and Shape:SolidMolecular weight:245.27MCI-225 dehydratase
CAS:MCI-225 dehydratase is an oral, selective inhibitor of noradrenaline reuptake, and functions as a 5-HT3 antagonist, exhibiting antidepressant effects in vivo .Formula:C17H18ClFN4SColor and Shape:SolidMolecular weight:364.87VU0029767
CAS:VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.
Formula:C21H21N3O3Color and Shape:SolidMolecular weight:363.41Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Formula:C26H27N3O6Color and Shape:SolidMolecular weight:477.51Aprofene
CAS:Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.Formula:C21H27NO2Color and Shape:SolidMolecular weight:325.44Diclofensine
CAS:Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine.Formula:C17H17Cl2NOPurity:97.01% - 98.13%Color and Shape:SolidMolecular weight:322.237-Acetoxy-1-methylquinolinium iodide
CAS:7-Acetoxy-1-methylquinolinium iodide (AMQI) is a cholinesterase substrate for inhibitor detection with 320 nm Ex and 410 nm Em.Formula:C12H12INO2Color and Shape:SolidMolecular weight:329.13Dianicline dihydrochloride
CAS:Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.Formula:C13H16N2OPurity:98%Color and Shape:SolidMolecular weight:216.286-hydroxy Buspirone
CAS:6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4.Formula:C21H31N5O3Color and Shape:SolidMolecular weight:401.50Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formula:C19H26N6OColor and Shape:SolidMolecular weight:354.45Pardoprunox
CAS:Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.Formula:C12H15N3O2Purity:98%Color and Shape:SolidMolecular weight:233.27Biperiden lactate
CAS:Biperiden lactate is a biochemical.Formula:C24H35NO4Color and Shape:SolidMolecular weight:401.544-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:319.22Aβ1-42 aggregation inhibitor 1
CAS:Aβ1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), demonstrating IC50 values of 2.64 μM and 1.29Formula:C29H32N4SColor and Shape:SolidMolecular weight:468.66N-Biotinyl p-aminophenyl arsenic acid
CAS:N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that binds to streptavidin and disulfide compounds. It diminishes the binding sites of rbungarotoxin on reduced nicotinic receptors with an IC50 ranging from 10-300 nM, thus shielding the receptors from irreversible alkylation by bromoacetylcholine.Formula:C16H22AsN3O4SColor and Shape:SolidMolecular weight:427.35SB 271046 hydrochloride
CAS:SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist and is > 200-fold selective over 55 other receptors, enzymes and ion channels.Formula:C20H22ClN3O3S2·HClPurity:99.77%Color and Shape:SolidMolecular weight:488.45Hydroxy ziprasidone
CAS:Hydroxy ziprasidone is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a 5-HT and dopamine receptor antagonist.Formula:C21H21ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:428.94Ketanserinol
CAS:Ketanserinol is a metabolite of the antihypertensive drug ketanserin, which blocks 5-HT2 receptors to treat protamine-induced pulmonary hypertension.Formula:C22H24FN3O3Color and Shape:SolidMolecular weight:397.44AN317
CAS:AN317 is a selective agonist for the nicotinic acetylcholine receptor (nAChR) containing α6β2, with dissociation constants (Ki) of 6.2 nM and 4.1 nM for the α6/α3β2β3 and α4β2 receptor subtypes, respectively. It induces dopamine release in rat striatal synaptosomes, enhances the activity of dopaminergic neurons in the substantia nigra, and exhibits protective effects against the dopaminergic neurotoxin MPP+ in rat neurons. AN317 also demonstrates favorable pharmacokinetic properties in rats and permeability across the blood-brain barrier (BB).Formula:C13H19N3Color and Shape:SolidMolecular weight:217.31Catestatin
CAS:Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.Formula:C107H173N37O26SPurity:98%Color and Shape:SolidMolecular weight:2425.84Phenglutarimide hydrochloride
CAS:Phenglutarimide hydrochloride is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H25ClN2O2Color and Shape:SolidMolecular weight:324.855-Methyltryptamine hydrochloride
CAS:5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.Formula:C11H15ClN2Purity:99.45%Color and Shape:SolidMolecular weight:210.703Penbutolol sulfate
CAS:Penbutolol sulfate ((-)-Terbuclomine) is able to bind to both β2-adrenergic receptor and β1-adrenergic receptor, thus making it a non-selective β blocker.Formula:C18H29NO2H2O4SPurity:99.95%Color and Shape:SolidMolecular weight:340.472-(4-Chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride
CAS:Controlled ProductFormula:C13H17Cl2NOColor and Shape:NeatMolecular weight:274.19(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid
CAS:Controlled ProductApplications (4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid (CAS# 53587-33-0) is a useful isotopically labeled research compound.
Formula:C9H8D2O4Color and Shape:NeatMolecular weight:184.192-(3-Chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride
CAS:Controlled ProductFormula:C13H17Cl2NOColor and Shape:NeatMolecular weight:274.196S-Nalfurafine
CAS:Controlled ProductApplications 6S-Nalfurafine is a stereoisomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)Formula:C28H32N2O5Color and Shape:NeatMolecular weight:476.562Z-Nalfurafine
CAS:Controlled ProductApplications 2Z-Nalfurafine is a geometric isomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)Formula:C28H32N2O5Color and Shape:NeatMolecular weight:476.56LY 344864
CAS:LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42Dolasetron Mesylate
CAS:Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea followingFormula:C20H24N2O6SPurity:99.05%Color and Shape:White PowderMolecular weight:420.48Paroxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Formula:C38H44Cl2F2N2O7Purity:99.949%Color and Shape:SolidMolecular weight:749.67YM 114
CAS:YM 114 is an anatagonist of 5-HT(3) receptor.Formula:C16H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:303.79(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Formula:C10H11NO4Purity:98.72%Color and Shape:SolidMolecular weight:209.20HexylHIBO
CAS:HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.Formula:C12H20N2O4Purity:99.55%Color and Shape:SolidMolecular weight:256.3Tilapertin
CAS:Tilapertin is an oral glycine transporter type-1 inhibitor.Formula:C20H21F3N2O2Purity:98%Color and Shape:SolidMolecular weight:378.39
