VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 268 products of "VEGFR"
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Anti-VEGFR2/KDR Antibody (5U735)
<p>Anti-VEGFR2/KDR Antibody (5U735) is a Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (5U735) can be used in ELISA,FCM.</p>Color and Shape:Odour LiquidVEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
<p>VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag.</p>Color and Shape:Lyophilized PowderMolecular weight:24.8 kDa (predicted)Anti-VEGFR2/KDR Antibody-PE (6M522)
<p>Anti-VEGFR2/KDR Antibody-PE (6M522) is a PE-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (6M522) can be used in FCM.</p>Color and Shape:Odour LiquidAnti-VEGFR2/KDR Antibody-APC (1T318)
<p>Anti-VEGFR2/KDR Antibody-APC (1T318) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (1T318) can be used in FCM.</p>Color and Shape:Odour LiquidSU 1498
CAS:Formula:C25H30N2O2Purity:>98.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:390.53Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805)
<p>Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805) is a Rabbit antibody targeting Phospho-VEGF Receptor 2 (Tyr1175). Anti-Phospho-VEGF Receptor 2 (Tyr1175) Antibody (7E805) can be used in WB.</p>Color and Shape:Odour LiquidAnti-VEGFR2/KDR Antibody (9T448)
<p>Anti-VEGFR2/KDR Antibody (9T448) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (9T448) can be used in ELISA.</p>Color and Shape:Odour LiquidVEGFR2/KDR Protein, Human, Recombinant (hFc)
<p>VEGFR2/KDR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:109 kDa (predicted); 150-160 kDa (reducing condition, due to glycosylation)VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
<p>VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:61.5 kDa (predicted)Anti-VEGFR2/KDR Antibody (6M522)
<p>Anti-VEGFR2/KDR Antibody (6M522) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (6M522) can be used in FCM.</p>Color and Shape:Odour LiquidAnti-VEGFR2/KDR Antibody (4D988)
<p>Anti-VEGFR2/KDR Antibody (4D988) is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody (4D988) can be used in ELISA.</p>Color and Shape:Odour LiquidAnti-VEGFR2/KDR Antibody-PE (4B612)
<p>Anti-VEGFR2/KDR Antibody-PE (4B612) is a PE-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-PE (4B612) can be used in FCM.</p>Color and Shape:Odour LiquidVEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
<p>VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:61.5 kDa (predicted)Anti-VEGFR2/KDR Antibody-FITC (4B612)
<p>Anti-VEGFR2/KDR Antibody-FITC (4B612) is a FITC-conjugated Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-FITC (4B612) can be used in FCM.</p>Color and Shape:Odour LiquidCediranib
CAS:Formula:C25H27FN4O3Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:450.51Anti-VEGFR2/KDR Antibody-APC (5U735)
<p>Anti-VEGFR2/KDR Antibody-APC (5U735) is a APC-conjugated Mouse antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Antibody-APC (5U735) can be used in FCM.</p>Color and Shape:Odour LiquidCZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34Regorafenib
CAS:<p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>Formula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82JNJ-38158471
CAS:<p>JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .</p>Formula:C15H17ClN6O3Purity:97.08%Color and Shape:SolidMolecular weight:364.79VEGFR-2-IN-5
CAS:<p>VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.</p>Formula:C19H24N8Purity:99.92%Color and Shape:SolidMolecular weight:364.45BMS-794833
CAS:<p>BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.</p>Formula:C23H15ClF2N4O3Purity:98% - 99.69%Color and Shape:SolidMolecular weight:468.84Gandotinib
CAS:<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94ZD-4190
CAS:<p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>Formula:C19H16BrFN6O2Purity:99.12%Color and Shape:SolidMolecular weight:459.27SKLB1002
CAS:<p>SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.</p>Formula:C13H12N4O2S2Purity:98.51% - >99.99%Color and Shape:SolidMolecular weight:320.39Lenvatinib mesylate
CAS:<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Formula:C22H23ClN4O7SPurity:99.03% - 99.79%Color and Shape:SolidMolecular weight:522.96PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83VEGFR2-IN-2
CAS:<p>VEGFR2-IN-2 has anti-inflammatory and analgesic activities.</p>Formula:C15H11BrN2OPurity:99.504%Color and Shape:SolidMolecular weight:315.16Ripretinib
CAS:<p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>Formula:C24H21BrFN5O2Purity:99.07% - 99.38%Color and Shape:SolidMolecular weight:510.36XL092
CAS:<p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>Formula:C29H25FN4O5Purity:98.60%Color and Shape:SolidMolecular weight:528.53TAK-659 hydrochloride
CAS:<p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>Formula:C17H22ClFN6OPurity:99.28% - 99.82%Color and Shape:SolidMolecular weight:380.85CP-673451
CAS:<p>CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other</p>Formula:C24H27N5O2Purity:99.62% - 99.88%Color and Shape:SolidMolecular weight:417.5(Z)-Guggulsterone
CAS:<p>(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.</p>Formula:C21H28O2Purity:98.93% - 99.72%Color and Shape:SolidMolecular weight:312.45Tanshinone IIA
CAS:<p>Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.</p>Formula:C19H18O3Purity:99.04% - >99.99%Color and Shape:Cherry CrystalMolecular weight:294.34Dovitinib lactate hydrate
CAS:<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Takeda-6d
CAS:<p>Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.</p>Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99AZD4547
CAS:<p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>Formula:C26H33N5O3Purity:99.37% - 99.88%Color and Shape:SolidMolecular weight:463.57Vandetanib
CAS:<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35PD173074
CAS:<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Formula:C28H41N7O3Purity:98.15% - 98.21%Color and Shape:Yellow SolidMolecular weight:523.67Pamufetinib mesylate
CAS:<p>Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.</p>Formula:C28H27FN4O7S2Purity:98.91%Color and Shape:SolidMolecular weight:614.67TAK-593
CAS:<p>TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).</p>Formula:C23H23N7O3Purity:99.37%Color and Shape:SolidMolecular weight:445.47Bevacizumab
CAS:<p>Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.</p>Purity:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Color and Shape:LiquidMolecular weight:146.53 kDaIsolinderalactone
CAS:<p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>Formula:C15H16O3Purity:99.62%Color and Shape:SolidMolecular weight:244.29PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Formula:C17H17N7Purity:98.45% - 99.67%Color and Shape:SolidMolecular weight:319.36SU4312
CAS:<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Formula:C17H16N2OPurity:>99.99%Color and Shape:SolidMolecular weight:264.32Semaxinib
CAS:<p>Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.</p>Formula:C15H14N2OPurity:99.84%Color and Shape:Yellow To Yellow OrangeMolecular weight:238.28ZM 306416
CAS:<p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).</p>Formula:C16H13ClFN3O2Purity:99.37% - ≥95%Color and Shape:SolidMolecular weight:333.74Vatalanib free base
CAS:<p>Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).</p>Formula:C20H15ClN4Purity:99.52%Color and Shape:SolidMolecular weight:346.81Sodium taurocholate
CAS:<p>Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.</p>Formula:C26H44NO7S·NaPurity:95% - 99.64%Color and Shape:White PowderMolecular weight:537.69Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64SU14813
CAS:<p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>Formula:C23H27FN4O4Purity:98.13%Color and Shape:SolidMolecular weight:442.48MGCD-265 analog
CAS:<p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>Formula:C26H20FN5O2S2Purity:98.06% - 98.68%Color and Shape:SolidMolecular weight:517.6R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Formula:C18H14ClFN4OPurity:98.422%Color and Shape:SolidMolecular weight:356.78Ribociclib
CAS:<p>Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).</p>Formula:C23H30N8OPurity:97.91% - >99.99%Color and Shape:SolidMolecular weight:434.54SAR131675
CAS:<p>SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.</p>Formula:C18H22N4O4Purity:99.74%Color and Shape:SolidMolecular weight:358.39Nintedanib esylate
CAS:<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>Formula:C31H33N5O4·C2H6O3SPurity:99.43% - 99.96%Color and Shape:SolidMolecular weight:649.76Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Formula:C24H24N4O5SPurity:98.97% - 99.88%Color and Shape:SolidMolecular weight:480.54Tyrphostin A9
CAS:<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Formula:C18H22N2OPurity:98.21% - 99.87%Color and Shape:Yellow SolidMolecular weight:282.38LY2874455
CAS:<p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>Formula:C21H19Cl2N5O2Purity:97.22% - 99.46%Color and Shape:SolidMolecular weight:444.31Telatinib
CAS:<p>Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.</p>Formula:C20H16ClN5O3Purity:97.61% - 99.81%Color and Shape:SolidMolecular weight:409.83Altiratinib
CAS:<p>Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,</p>Formula:C26H21F3N4O4Purity:99.67% - 99.75%Color and Shape:SolidMolecular weight:510.46SU5408
CAS:<p>SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.</p>Formula:C18H18N2O3Purity:99.35%Color and Shape:SolidMolecular weight:310.35Gamabufotalin
CAS:<p>Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.</p>Formula:C24H34O5Purity:99.18% - 99.51%Color and Shape:SolidMolecular weight:402.52WHI-P180
CAS:<p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>Formula:C16H15N3O3Purity:99.21%Color and Shape:SolidMolecular weight:297.31SU 5402
CAS:<p>SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.</p>Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32SKLB 610
CAS:<p>SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,</p>Formula:C21H16F3N3O3Purity:99.33% - 99.83%Color and Shape:SolidMolecular weight:415.37SU5204
CAS:<p>SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and</p>Formula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31Tivozanib
CAS:<p>Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.</p>Formula:C22H19ClN4O5Purity:98.08% - 99.67%Color and Shape:SolidMolecular weight:454.86MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38AZD2932
CAS:<p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Xanthatin
CAS:<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Formula:C15H18O3Purity:98.48% - 99.96%Color and Shape:SolidMolecular weight:246.3Dovitinib lactate
CAS:<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51AAL-993
CAS:<p>AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.</p>Formula:C20H16F3N3OPurity:99.65%Color and Shape:SolidMolecular weight:371.36RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41NVP-BAW2881
CAS:<p>NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.</p>Formula:C22H15F3N4O2Purity:98.19% - 99.97%Color and Shape:SolidMolecular weight:424.38SU5205
CAS:<p>SU5205 is a VEGFR2 inhibitor.</p>Formula:C15H10FNOPurity:99.62% - 99.67%Color and Shape:SolidMolecular weight:239.24Foretinib
CAS:<p>Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.</p>Formula:C34H34F2N4O6Purity:98.07% - 99.68%Color and Shape:SolidMolecular weight:632.65Vorolanib
CAS:<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Fruquintinib
CAS:<p>Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-</p>Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35AG-13958
CAS:<p>AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.</p>Formula:C26H22FN7OPurity:99.4%Color and Shape:SolidMolecular weight:467.5Motesanib
CAS:<p>Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.</p>Formula:C22H23N5OPurity:98% - 99.09%Color and Shape:SolidMolecular weight:373.45KRN-633
CAS:<p>KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.</p>Formula:C20H21ClN4O4Purity:99.53% - 99.73%Color and Shape:SolidMolecular weight:416.86JI-101
CAS:<p>JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.</p>Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51SCR-1481B1
CAS:<p>SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor</p>Formula:C32H40ClF2N6O13PPurity:98.07%Color and Shape:SolidMolecular weight:821.12Oglufanide
CAS:<p>Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).</p>Formula:C16H19N3O5Purity:99.80%Color and Shape:SolidMolecular weight:333.34EOC317
CAS:<p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>Formula:C27H26F5N7O3Purity:98.00% - 99.26%Color and Shape:SolidMolecular weight:591.53SU5208
CAS:<p>SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).</p>Formula:C13H9NOSPurity:99.62%Color and Shape:SolidMolecular weight:227.28Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98KI8751
CAS:<p>KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.</p>Formula:C24H18F3N3O4Purity:99.22% - 99.9%Color and Shape:SolidMolecular weight:469.41Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46Golvatinib
CAS:<p>Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor</p>Formula:C33H37F2N7O4Purity:98.24% - ≥95%Color and Shape:SolidMolecular weight:633.69Ningetinib Tosylate
CAS:<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Formula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56
