Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1424 products of "Autophagy"
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Reserpine
CAS:<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formula:C33H40N2O9Purity:98.85% - 99.81%Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Molecular weight:608.68Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Formula:C24H25FNNaO4Purity:98.54% - 99.56%Color and Shape:Light Yellow Solid PowderMolecular weight:433.45Pterostilbene
CAS:<p>Pterostilbene is extracted from Pterocarpus indicus.</p>Formula:C16H16O3Purity:99.20%Color and Shape:Off-White Crystalline PowderMolecular weight:256.33,3'-Diindolylmethane
CAS:<p>3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.</p>Formula:C17H14N2Purity:99.09%Color and Shape:SolidMolecular weight:246.31Raloxifene hydrochloride
CAS:<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Formula:C28H28ClNO4SPurity:98% - 99.97%Color and Shape:Light Yellow SolidMolecular weight:510.044Berberine chloride
CAS:<p>Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.</p>Formula:C20H18ClNO4Purity:99.47% - 99.93%Color and Shape:Yellow Crystalline PowderMolecular weight:371.8Indazole
CAS:<p>Indazole, a heterocyclic compound, offers diverse biological activities.</p>Formula:C7H6N2Purity:99.59% - 99.85%Color and Shape:White Or Beige Crystalline PowderMolecular weight:118.14Vinorelbine
CAS:<p>Vinorelbine, a semisynthetic vinca alkaloid, inhibits tubulin, blocking mitotic spindle formation and tumor growth.</p>Formula:C45H54N4O8Purity:98.62% - 99.99%Color and Shape:SolidMolecular weight:778.93Metyrapone
CAS:<p>Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.</p>Formula:C14H14N2OPurity:99.03% - ≥95%Color and Shape:Crystals From Ether & Pentane SolidMolecular weight:226.27Telmisartan
CAS:<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Formula:C33H30N4O2Purity:99.88% - 99.97%Color and Shape:White Or Off White Crystalline PowderMolecular weight:514.62Retinoic acid
CAS:<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44Myricetin
CAS:<p>Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.</p>Formula:C15H10O8Purity:97.92% - 99.85%Color and Shape:Yellow Needles From Dilute Alcohol SolidMolecular weight:318.24Dexamethasone
CAS:<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Formula:C22H29FO5Purity:98% - 99.91%Color and Shape:Crystals From Ether (Ntp 1992)Molecular weight:392.46Phenformin hydrochloride
CAS:<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formula:C10H16ClN5Purity:97.11% - 99.80%Color and Shape:Lactic AcidosisMolecular weight:241.72Mevastatin
CAS:<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formula:C23H34O5Purity:99.12%Color and Shape:White-Yellowish To Yellow Powder Solid PowderMolecular weight:390.51Cytarabine
CAS:<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Formula:C9H13N3O5Purity:99.83% - 99.93%Color and Shape:Fine Off-White Crystalline PowderMolecular weight:243.22Erlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Sophocarpine monohydrate
CAS:<p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formula:C15H22N2OPurity:99.55%Color and Shape:SolidMolecular weight:246.35AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Formula:C27H30FN5O3Purity:98.82%Color and Shape:SolidMolecular weight:491.56Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formula:C8H14N2O4PtPurity:97% - 99.93%Color and Shape:SolidMolecular weight:397.29Thalidomide
CAS:<p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>Formula:C13H10N2O4Purity:98.88% - 99.88%Color and Shape:White SolidMolecular weight:258.23Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46Doxazosin mesylate
CAS:<p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>Formula:C24H29N5O8SPurity:99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:547.58Vancomycin hydrochloride
CAS:<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Formula:C66H76Cl3N9O24Purity:97.20% - 99.19%Color and Shape:Off White PowderMolecular weight:1485.71ZX-29
CAS:<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Formula:C23H28ClN7O3SPurity:98.32%Color and Shape:SolidMolecular weight:518.03LG-100064
CAS:<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Formula:C23H26O3Purity:98.65%Color and Shape:SolidMolecular weight:350.45Pictilisib dimethanesulfonate
CAS:<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Formula:C25H35N7O9S4Purity:99.63%Color and Shape:SolidMolecular weight:705.85Sulfadoxine
CAS:<p>Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial</p>Formula:C12H14N4O4SPurity:99.67%Color and Shape:White Or White Crystalline PowderMolecular weight:310.33Lomustine
CAS:<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Formula:C9H16ClN3O2Purity:98.36% - 99.44%Color and Shape:Solid SolidMolecular weight:233.7Trimetazidine dihydrochloride
CAS:<p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>Formula:C14H24Cl2N2O3Purity:99.58%Color and Shape:Crystalline SolidMolecular weight:339.258Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formula:C27H44O7Purity:99.06% - 99.67%Color and Shape:Canary Yellow Fine PowderMolecular weight:480.63Vitamin B3-d4
CAS:<p>Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.</p>Formula:C6HD4NO2Purity:99.86%Color and Shape:SolidMolecular weight:127.13Doxorubicin hydrochloride
CAS:<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Formula:C27H29NO11·HClPurity:98% - 99.52%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.99Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purity:98.22% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09NBDHEX
CAS:<p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>Formula:C12H15N3O4SPurity:97.38%Color and Shape:SolidMolecular weight:297.33Silmitasertib sodium salt
CAS:<p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>Formula:C19H11ClN3NaO2Purity:99.49% - 99.62%Color and Shape:SolidMolecular weight:371.75Irinotecan Hydrochloride
CAS:<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow Crystalline PowderMolecular weight:623.14Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Paclitaxel
CAS:<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formula:C47H51NO14Purity:98% - 99.92%Color and Shape:White PowderMolecular weight:853.91Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00Deferoxamine Mesylate
CAS:<p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>Formula:C26H52N6O11SPurity:94.68% - 99.8%Color and Shape:SolidMolecular weight:656.79Rhein
CAS:<p>Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.</p>Formula:C15H8O6Purity:99.04%Color and Shape:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)Molecular weight:284.22MLi-2
CAS:<p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>Formula:C21H25N5O2Purity:98.96%Color and Shape:SolidMolecular weight:379.46Spironolactone
CAS:<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57BIX 02565
CAS:<p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>Formula:C26H30N6O2Purity:97.44% - 99.7%Color and Shape:SolidMolecular weight:458.56Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formula:C24H40O4Purity:99.70% - 99.93%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Salicylic acid
CAS:<p>Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.</p>Formula:C7H6O3Purity:98.04% - 98.83%Color and Shape:White Solid PowderMolecular weight:138.12Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Formula:C21H16ClF3N4O3·C7H8O3SPurity:99.24% - 99.94%Color and Shape:White To Off-White Crystalline PowderMolecular weight:637.03Trifluoperazine dihydrochloride
CAS:<p>Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.</p>Formula:C21H26Cl2F3N3SPurity:99.57% - 99.96%Color and Shape:Cream Fine PowderMolecular weight:480.43
