GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5838 products of "GPCR/G-Protein"

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Spantide acetate
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
Formula:C₇₇H₁₁₂N₂₀O₁₅
Purity:98.9200%
Color and Shape:Solid
Molecular weight:1557.84
Ref: TM-T20413L
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Ghrelin receptor full agonist-2
CAS:
- 2602452-73-1
Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.
Formula:C₂₆H₂₈ClN₅O₅S
Color and Shape:Solid
Molecular weight:558.05
Ref: TM-T40234
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11-deoxy Prostaglandin E1
CAS:
- 37786-00-8
11-deoxy Prostaglandin E1 is a prostaglandin E1 analogue that has bronchodilator activity and can inhibit histamine-induced bronchoconstriction and cause
Formula:C₂₀H₃₄O₄
Color and Shape:Solid
Molecular weight:338.48
Ref: TM-T36770
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Galanin (1-16), mouse, porcine, rat TFA
Galanin (1-16) agonizes hippocampal receptors; Kd 3 nM. Active on locus coeruleus neurons in mice, pigs, rats.
Formula:C₈₀H₁₁₇F₃N₂₀O₂₃
Purity:98%
Color and Shape:Solid
Molecular weight:1783.9
Ref: TM-TP1317
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5-HT2C agonist-4
CAS:
- 2730085-33-1
Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.
Formula:C₂₄H₂₅N₅O
Color and Shape:Solid
Molecular weight:399.49
Ref: TM-T203570
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BQ-123 TFA
BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.
Formula:C₃₃H₄₃F₃N₆O₉
Color and Shape:Solid
Molecular weight:724.72
Ref: TM-T73877
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MI 1544
CAS:
- 87565-51-3
MI 1544 is a LHRH antagonist.
Formula:C₇₁H₉₄ClN₁₇O₁₃
Color and Shape:Solid
Molecular weight:1429.09
Ref: TM-T25808
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Benzquinamide
CAS:
- 63-12-7
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer
Formula:C₂₂H₃₂N₂O₅
Purity:94.86%
Color and Shape:Solid
Molecular weight:404.5
Ref: TM-T12343
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Sch 202596
CAS:
- 196615-89-1
Sch 202596 is a selective non-peptide antagonist of GAL-1 receptor.
Formula:C₂₅H₂₂Cl₂O₁₂
Color and Shape:Solid
Molecular weight:585.34
Ref: TM-T28705
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Fpl 14294
CAS:
- 154132-95-3
Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat.
Formula:C₄₅H₅₆N₈O₁₃S₃
Purity:98%
Color and Shape:Solid
Molecular weight:1013.17
Ref: TM-T25437
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Velmupressin acetate
CAS:
- 1647120-04-4
Potent, selective, short-acting peptidic V2R agonist; EC50: 0.07 nM (hV2R), 0.02 nM (rV2R).
Formula:C₄₄H₆₄ClN₁₁O₁₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1006.63
Ref: TM-TP1205
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Somatostatin 1-28 acetate
Somatostatin 1-28 acetate circulates in human plasma.
Purity:99.22%
Color and Shape:Soild
Ref: TM-TP2124L
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Human growth hormone-releasing factor
CAS:
- 83930-13-6
GHRH from the hypothalamus prompts the pituitary to produce/release GH by attaching to the GHRHR.
Formula:C₂₁₅H₃₅₈N₇₂O₆₆S
Purity:98%
Color and Shape:Solid
Molecular weight:5039.65
Ref: TM-TP1155
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K-(D-1-Nal)-FwLL-NH2
CAS:
- 1394288-22-2
Potent ghrelin receptor inverse agonist with Ki of 4.9/31 nM in COS7/HEK293T; blocks Gq/G13 signaling.
Formula:C₅₁H₆₇N₉O₆
Purity:98%
Color and Shape:Solid
Molecular weight:902.13
Ref: TM-TP1894
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Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA
Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist.
Formula:C₂₁₂H₃₁₆F₃N₅₇O₅₉S
Purity:98%
Color and Shape:Solid
Molecular weight:4696.18
Ref: TM-T10251
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L-797,591 hydrochloride
L-797,591 HCl activates SSTR1, boosts p-ERK5 with AG1478, and enhances p38 phosphorylation, reversible by AG1478.
Formula:C₃₈H₅₀ClN₅O₂
Purity:98.65% - >99.99%
Color and Shape:Soild
Molecular weight:644.30
Ref: TM-T27787L
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1-39-Corticotropin (human)(TFA)
ACTH (1-39) human (TFA) is a melanocortin agonist that boosts adrenal CS production and affects the CNS and immune system.
Formula:C₂₀₇H₃₀₈N₅₆O₅₈S·C₂HF₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:4655.16
Ref: TM-TP1242
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Levocarnitine propionate hydrochloride
CAS:
- 119793-66-7
Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, and other diseases.
Formula:C₁₀H₂₀ClNO₄
Purity:90% - 99.77%
Color and Shape:Solid
Molecular weight:253.72
Ref: TM-T1182
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Physalaemin
CAS:
- 2507-24-6
Physalaemin is a non-mammalian tachykinin.
Formula:C₅₈H₈₄N₁₄O₁₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1265.45
Ref: TM-T19518
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α-Bulnesene
CAS:
- 3691-11-0
α-Bulnesene, a novel PAF (platelet-activating factor) receptor antagonist, exhibits an IC50 of 17.62 μM. It can be isolated from patchouli. α-Bulnesene inhibits both PAF and arachidonic acid-induced aggregation of rabbit platelets.
Formula:C₁₅H₂₄
Color and Shape:Solid
Molecular weight:204.35
Ref: TM-TN8025
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Cetirizine methyl ester
CAS:
- 83881-46-3
Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.
Formula:C₂₂H₂₇ClN₂O₃
Color and Shape:Solid
Molecular weight:402.91
Ref: TM-T73933
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Xenopus orexin B
CAS:
- 254757-78-3
Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].
Formula:C₁₃₀H₂₁₉N₄₅O₄₀S₂
Color and Shape:Solid
Molecular weight:3116.54
Ref: TM-TP2641
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GLP-1 (9-36) amide
CAS:
- 161748-29-4
GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor.
Formula:C₁₄₀H₂₁₄N₃₆O₄₃
Purity:97%
Color and Shape:Solid
Molecular weight:3089.41
Ref: TM-TP2252
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T-10430
T-10430 is a potent and orally active agonist of the leukotriene B4 receptor 2 (BLT2). It shows potential for use in psoriasis research.
Formula:C₁₇H₂₂N₆O
Color and Shape:Solid
Molecular weight:326.396
Ref: TM-T204318
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Substance P(1-7)
CAS:
- 68060-49-1
Substance P(1-7) is a bioactive metabolite of tachykinin SP with anti-inflammatory and analgesic properties.
Formula:C₄₁H₆₅N₁₃O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:900.04
Ref: TM-T7396
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Secretoneurin, rat
CAS:
- 149146-12-3
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII).
Formula:C₁₅₉H₂₅₂N₄₀O₅₈
Purity:98%
Color and Shape:Solid
Molecular weight:3651.95
Ref: TM-TP1597
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16,16-dimethyl Prostaglandin F2α
CAS:
- 39746-23-1
16,16-dimethyl Prostaglandin F2α can be used in related research in the field of life sciences. Its product number is T37993 and CAS number is 39746-23-1.
Formula:C₂₂H₃₈O₅
Color and Shape:Solid
Molecular weight:382.541
Ref: TM-T37993
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PAR 4 (1-6) (TFA)
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.
Formula:C₂₈H₄₁N₇O₉·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T75904
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[Nle11]-Substance P
CAS:
- 57462-42-7
'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formula:C₆₄H₁₀₀N₁₈O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1329.59
Ref: TM-TP1831
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Dexchlorpheniramine free base
CAS:
- 25523-97-1
Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
Formula:C₁₆H₁₉ClN₂
Purity:98%
Color and Shape:Oily Liquid Solid
Molecular weight:274.79
Ref: TM-T0785L
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Mitemcinal fumarate
CAS:
- 154802-96-7
Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.
Formula:C₈₄H₁₄₂N₂O₂₈
Color and Shape:Solid
Molecular weight:1628.02
Ref: TM-T33402
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AGN 191976
CAS:
- 159359-94-1
AGN 191976 is a novel thromboxane A2-mimetic.
Formula:C₂₁H₃₂O₆
Color and Shape:Solid
Molecular weight:380.481
Ref: TM-T29722
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Endothelin-3, human, mouse, rabbit, rat
CAS:
- 117399-93-6
Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.
Formula:C₁₂₁H₁₆₈N₂₆O₃₃S₄
Purity:98%
Color and Shape:Solid
Molecular weight:2643.04
Ref: TM-TP1175
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ACTH (11-24)
CAS:
- 4237-93-8
ACTH (11-24) is an adrenocorticotrophin fragment, stimulates cortisol, and antagonizes ACTH (1-39)/(1-10) in adrenal cells.
Formula:C₇₇H₁₃₄N₂₄O₁₆
Purity:98%
Color and Shape:Solid
Molecular weight:1652.04
Ref: TM-TP1248
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Sorbinicate
CAS:
- 6184-06-1
Sorbinicate is an antihypercholesterolaemic and vasodilating nicotinic acid ester.
Formula:C₄₂H₃₂N₆O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:812.74
Ref: TM-T26201
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[Pro34]Neuropeptide Y, porcine
CAS:
- 128768-54-7
[Pro34]Neuropeptide Y, porcine functions as a selective agonist for the NPY (Y1) receptor and induces vasoconstriction in the guinea pig's caval vein [1].
Formula:C₁₉₀H₂₈₆N₅₄O₅₆
Color and Shape:Solid
Molecular weight:4222.63
Ref: TM-TP2523
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Vortioxetine D8
CAS:
- 2140316-62-5
Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).
Formula:C₁₈H₂₂N₂S
Purity:98%
Color and Shape:Solid
Molecular weight:306.5
Ref: TM-T13308
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Brexpiprazole S-oxide D8
CAS:
- 2748605-29-8
Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.
Formula:C₂₅H₁₉D₈N₃O₃S
Purity:98%
Color and Shape:Solid
Molecular weight:457.61
Ref: TM-T10611
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Suntinorexton
CAS:
- 2274802-89-8
Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.
Formula:C₂₃H₂₈F₂N₂O₄S
Purity:99.89%
Color and Shape:Solid
Molecular weight:466.54
Ref: TM-T39807
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NESS 0327
CAS:
- 494844-07-4
NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.
Formula:C₂₄H₂₃Cl₃N₄O
Purity:99.78%
Color and Shape:Solid
Molecular weight:489.82
Ref: TM-T22114
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15(S)-15-methyl Prostaglandin E2
CAS:
- 35700-27-7
15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.
Formula:C₂₁H₃₄O₅
Color and Shape:Solid
Molecular weight:366.49
Ref: TM-T36154
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Thromboxane B1
CAS:
- 64626-32-0
Thromboxane B1 (TXB1) is a lipid eicosanoid, part of the TXB family, involved in blood clotting.
Formula:C₂₀H₃₆O₆
Color and Shape:Solid
Molecular weight:372.5
Ref: TM-T73855
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Corynanthine
CAS:
- 483-10-3
Corynanthe is a plant alkaloid. Corynanthe also has an alpha-2-adrenergic blocking activity.
Formula:C₂₁H₂₆N₂O₃
Purity:98%
Color and Shape:Solid
Molecular weight:354.44
Ref: TM-T19910
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4-fluoro MBZP
CAS:
- 144734-44-1
4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.
Formula:C₁₂H₁₇FN₂
Color and Shape:Solid
Molecular weight:208.28
Ref: TM-T203276
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LP 12 hydrochloride
CAS:
- 1185136-22-4
LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).
Formula:C₃₂H₄₀ClN₃O
Color and Shape:Solid
Molecular weight:518.14
Ref: TM-T37073
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[Des-Arg9]-Bradykinin acetate
CAS:
- 23827-91-0
[Des-Arg9]-Bradykinin acetate is a selective agonist of Bradykinin B1 receptor.
Formula:C₄₆H₆₅N₁₁O₁₂
Purity:99.05%
Color and Shape:Solid
Molecular weight:964.07
Ref: TM-TP1445
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Tryptamine hydrochloride
CAS:
- 343-94-2
Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.
Formula:C₁₀H₁₃ClN₂
Purity:99.89%
Color and Shape:Solid
Molecular weight:196.68
Ref: TM-T124997
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Guanylin TFA (mouse,rat)
Guanylin (mouse, rat) TFA is a peptide composed of 15 amino acids and acts as an activator of intestinal guanylate cyclase. This compound is utilized in research related to diarrhea.
Formula:C₆₀H₉₀N₁₆O₂₂S₄·xC₂HF₃O₂
Color and Shape:Solid
Molecular weight:1515.71 (free base)
Ref: TM-TP2847
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15-keto-17-phenyl trinor Prostaglandin F2α
CAS:
- 949564-89-0
Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
Formula:C₂₃H₃₀O₅
Color and Shape:Solid
Molecular weight:386.488
Ref: TM-T37934
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PACAP (6-38), human, ovine, rat TFA
PACAP (6-38) is a PACAP receptor blocker with IC50s of 30, 600, 40 nM for type I, VIP1, and VIP2 receptors.
Formula:C₁₈₄H₃₀₁N₅₆FO₄₇S
Purity:98%
Color and Shape:Solid
Molecular weight:4138.76
Ref: TM-TP1438
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Bremelanotide
CAS:
- 189691-06-3
Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.
Formula:C₅₀H₆₈N₁₄O₁₀
Purity:98%
Color and Shape:White Powder
Molecular weight:1025.16
Ref: TM-T20467
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Amitraz
CAS:
- 33089-61-1
Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.
Formula:C₁₉H₂₃N₃
Purity:99.88%
Color and Shape:White/Pale Yellow Crystalline Solid
Molecular weight:293.41
Ref: TM-T1632
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Pentagastrin meglumine
CAS:
- 57448-84-7
Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.
Formula:C₄₄H₆₆N₈O₁₄S
Color and Shape:Solid
Molecular weight:963.11
Ref: TM-T33916
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(D-Ala2)-GRF (1-29) amide (human)
CAS:
- 89453-59-8
(D-Ala2)-GRF (1-29) amide (human) is a potent superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating an exceptionally high Growth Hormone (GH)-
Formula:C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular weight:3357.88
Ref: TM-T83549
+ Info
AdTx1
Selective non-competitive α1A adrenoceptor antagonist with Ki of 0.35 nM; inactive on other GPCRs; affects phenylephrine actions.
Formula:C₃₁₀H₄₈₁N₈₇O₁₀₀S₈
Purity:98%
Color and Shape:Solid
Molecular weight:7283.22
Ref: TM-TP2086
+ Info
Taspoglutide
CAS:
- 275371-94-3
Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes
Formula:C₁₅₂H₂₃₂N₄₀O₄₅
Purity:98%
Color and Shape:Solid
Molecular weight:3339.763
Ref: TM-T13091
+ Info
KwFwLL-NH2
CAS:
- 942266-38-8
KwFwLL-NH2 is a hexapeptide that serves as a ligand for the ghrelin receptor (ghrelin receptor). This compound acts as a specific inverse agonist for the ghrelin receptor, exhibiting moderate potency (EC50=45.6 nM).
Formula:C₄₉H₆₆N₁₀O₆
Color and Shape:Solid
Molecular weight:891.11
Ref: TM-TP2863
+ Info
Lys-[Des-Arg9]Bradykinin TFA
CAS:
- 2763588-90-3
Lys-[Des-Arg9]Bradykinin TFA: natural kinin, selective B1 agonist; Ki: 0.12 nM (human), 1.7 nM (mouse), 0.23 nM (rabbit); weak on B2 receptors.
Formula:C₅₄H₇₅F₆N₁₃O₁₅
Color and Shape:Solid
Molecular weight:1260.24
Ref: TM-T73646
+ Info
[Des-Arg10]-HOE I40 TFA
[Des-Arg10]-HOE I40 TFA is a potent antagonist of the bradykinin B1 receptor.
Formula:C₅₃H₇₇N₁₅O₁₂S·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T207446
+ Info
β-CGRP (mouse)
β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.
Formula:C₁₆₅H₂₆₅N₄₉O₅₅S₂
Color and Shape:Solid
Molecular weight:3879.29
Ref: TM-TP2859
+ Info
Mosapride citrate dihydrate
CAS:
- 636582-62-2
Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.
Formula:C₂₇H₃₅ClFN₃O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:632.04
Ref: TM-T6597L
+ Info
Neurokinin B (TFA)
CAS:
- 101536-55-4
Neurokinin B TFA, a tachykinin, targets NK1R, NK2R, nk3r GPCRs, modulating effects.
Formula:C₅₉H₈₁F₆N₁₃O₁₈S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1438.47
Ref: TM-TP1279
+ Info
(Iso)-Landipirdine
CAS:
- 1000308-09-7
(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.
Formula:C₁₈H₁₉FN₂O₃S
Purity:98.50%
Color and Shape:Soild
Molecular weight:362.42
Ref: TM-T27795L
+ Info
Adenosine receptor agonist 1
Compound 6m, an A3 adenosine receptor (AR) partial agonist, exhibits a K i value of 6.7 nM as an adenosine receptor agonist.
Formula:C₁₂H₁₄ClN₅O₂Se
Color and Shape:Solid
Molecular weight:374.68
Ref: TM-T89890
+ Info
PAMP-12(human, porcine)
CAS:
- 196305-05-2
Potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.
Formula:C₇₇H₁₁₉N₂₅O₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:1618.95
Ref: TM-TP1880
+ Info
Y1 receptor antagonist 1 formic
H 409-22 isomer formic, a formate salt of Y1 receptor antagonist 1, is an antagonist of the neuropeptide Y1 receptor (neuropeptide Y1 receptor). This compound effectively blocks the actions of the receptor, playing a crucial role in modulating physiological responses.
Formula:C₂₉H₃₅N₅O₅
Color and Shape:Solid
Molecular weight:533.62
Ref: TM-T200259
+ Info
Adrenomedullin (1-50), rat
CAS:
- 159964-38-2
Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.
Formula:C₂₄₈H₃₈₁N₇₇O₇₅S₅
Purity:98%
Color and Shape:Solid
Molecular weight:5729.5
Ref: TM-TP1764
+ Info
[8-L-arginine] deaminovasopressin
CAS:
- 25255-33-8
[8-L-arginine] deaminovasopressin (dAVP) is a vasopressin analog [1] .
Formula:C₄₆H₆₄N₁₄O₁₃S₂
Color and Shape:Solid
Molecular weight:1085.22
Ref: TM-T76573
+ Info
SAE-14
CAS:
- 1241280-25-0
GPR183, a chemotactic receptor aiding B cell maturation, binds 7α,25-OHC; studied in IBD research.
Formula:C₁₉H₁₉F₃N₂O₂
Purity:99.85%
Color and Shape:Solid
Molecular weight:364.36
Ref: TM-T9975
+ Info
LSN3160440
CAS:
- 2765539-59-9
LSN3160440 is a GLP-1R allosteric modulator and PPI stabilizer aiding inactive GLP-1 attachment.
Formula:C₂₇H₂₇Cl₂N₃O
Color and Shape:Solid
Molecular weight:480.43
Ref: TM-T75112
+ Info
Adrogolide HCl
CAS:
- 166591-11-3
Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.
Formula:C₂₂H₂₆ClNO₄S
Color and Shape:Solid
Molecular weight:435.96
Ref: TM-T29674
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Antisauvagine-30 TFA
aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).
Formula:C₁₆₃H₂₇₅N₄₈F₃O₄₉S
Color and Shape:Solid
Molecular weight:3764.28
Ref: TM-T75805
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Asenapine citrate
CAS:
- 1411867-74-7
Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).
Formula:C₂₃H₂₄ClNO₈
Color and Shape:Solid
Molecular weight:477.89
Ref: TM-T63129
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MMC(TMZ)-TOC TFA
MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.
Formula:C₇₄H₉₉F₃N₂₀O₂₁S₂
Color and Shape:Solid
Molecular weight:1725.82
Ref: TM-T204151
+ Info
SDV-Exendin-3/4
SDV-Exendin-3/4 is a 32-amino acid peptide.
Formula:NA
Purity:98%
Color and Shape:Solid
Molecular weight:3443.87
Ref: TM-TP1461
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SFNGGP-NH2
CAS:
- 261521-21-5
SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor.
Formula:C₂₅H₃₆N₈O₈
Color and Shape:Solid
Molecular weight:576.6
Ref: TM-T80234
+ Info
Septide
CAS:
- 79775-19-2
Septide is an NK1 receptor agonist acting at a site distinct from substance P.
Formula:C₃₉H₅₃N₇O₇S
Purity:98%
Color and Shape:Solid
Molecular weight:763.95
Ref: TM-TP2352
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Secretin (28-54), human TFA
Secretin (28-54), human TFA is a 27-amino acid peptide that works on the human Secretin receptor.
Formula:C₁₃₂H₂₂₁N₄₄F₃O₄₂
Purity:98%
Color and Shape:Solid
Molecular weight:3153.48
Ref: TM-TP1135
+ Info
DOTA-LM3 TFA
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist with the molecular structure p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2.
Formula:C₇₁H₉₄ClF₃N₁₆O₂₁S₂
Color and Shape:Solid
Molecular weight:1664.18
Ref: TM-T78110
+ Info
CHS-114
CHS-114 (SRF-114) is a fully human IgG1 antibody targeting the (CCR8) receptor. It shows potential for research in head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can be referred to as HumanIgG1kappa, Isotype Control.
Color and Shape:Odour Liquid
Ref: TM-T9901A-769
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APJ receptor agonist 4
CAS:
- 2135515-67-0
Potent, orally active APJ receptor agonist 4; EC50: 0.06 nM, Ki: 0.07 nM; good pharmacokinetics in rodent HF model; safe in studies; boosts cardiac function.
Formula:C₂₈H₂₈ClFN₆O₃
Color and Shape:Solid
Molecular weight:551.02
Ref: TM-T39587
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Desglymidodrine
CAS:
- 3600-87-1
Desglymidodrine (ST 1059) is an α1-adrenoceptor agonist and vasoconstrictor, used in cardiovascular research and neurocardiogenic syncope studies.
Formula:C₁₀H₁₅NO₃
Purity:99.56%
Color and Shape:Solid
Molecular weight:197.23
Ref: TM-T31388L
+ Info
CCR6 antagonist 2
CCR6 antagonist2 (Compound 20c) acts as a CCR6 antagonist with a Ki of 1.1 nM. It inhibits CCL20-induced calcium influx with an IC50 of 4.9 nM and suppresses the chemotactic migration of CCR6+ T cells with an IC50 of 190 nM.
Formula:C₁₉H₂₄N₄O₄
Color and Shape:Solid
Molecular weight:372.42
Ref: TM-T205072
+ Info
MrgprX2 antagonist-5
CAS:
- 2527815-74-1
MrgprX2 antagonist-5 from patent WO2020223255A1 inhibits MrgprX2, useful for inflammatory skin disorder studies.
Formula:C₁₉H₁₃ClF₂N₄O₂S
Color and Shape:Solid
Molecular weight:434.85
Ref: TM-T40176
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d[Cha4]-AVP
CAS:
- 500170-27-4
Potent human V1B vasopressin receptor agonist; Ki: V1B=1.2 nM; increases ACTH, corticosterone; low vasopressor effect.
Formula:C₅₀H₇₁N₁₃O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1094.31
Ref: TM-TP2082
+ Info
PAR 4 (1-6)
CAS:
- 225779-44-2
PAR 4 (1-6) can be used for relevant research in the life sciences. Its product number is T36293 and CAS number is 225779-44-2.
Formula:C₂₈H₄₁N₇O₉
Color and Shape:Solid
Molecular weight:619.676
Ref: TM-T36293
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CB1R antagonist 2
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.
Formula:C₂₄H₂₆N₄O
Color and Shape:Solid
Molecular weight:386.49
Ref: TM-T205110
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Scyliorhinin II
CAS:
- 112748-19-3
Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.
Formula:C₇₇H₁₁₉N₂₁O₂₆S₃
Purity:98%
Color and Shape:Solid
Molecular weight:1851.09
Ref: TM-TP1851
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Neuropeptide AF (cattle)
CAS:
- 99588-52-0
Neuropeptide AF (cattle) is an RFamide that acts on MrgprA4 (~60 nM), MrgprC11 (~300 nM), NPFF1 (~25-325 nM), NPFF2 (~1-5 nM), and modulates pain.
Formula:C₈₉H₁₃₀N₂₄O₂₄
Color and Shape:Solid
Molecular weight:1920.13
Ref: TM-T76423
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Phoenixin-14 TFA
Phoenixin-14 TFA (PNX-14 TFA) is an endogenous neuropeptide that can modulate GnRH receptor expression and exerts anxiolytic effects.
Formula:C₇₅H₁₁₀N₁₈O₂₀·xC₂HF₃O₂
Purity:99.11%
Color and Shape:Solid
Molecular weight:1583.78 (free base)
Ref: TM-T81485
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Neuromedin N
CAS:
- 92169-45-4
Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
Formula:C₃₈H₆₃N₇O₈
Purity:98%
Color and Shape:Solid
Molecular weight:745.95
Ref: TM-TP1085
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Thioperamide maleate
CAS:
- 148440-81-7
Thioperamide maleate (MR-12842 maleate) is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31
Formula:C₁₉H₂₈N₄O₄S
Purity:98.48%
Color and Shape:Solid
Molecular weight:408.52
Ref: TM-T41247
+ Info
Hemopressin(rat)
CAS:
- 568588-77-2
Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.
Formula:C₅₃H₇₇N₁₃O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1088.27
Ref: TM-TP1901
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NR2E3 agonist 1
CAS:
- 911211-69-3
NR2E3 agonist 1 is an NR2E3 agonist with antitumor activity and can be used to study diseases caused by NR2E3 abnormalities.
Formula:C₂₄H₁₉ClN₄O₂
Purity:98.88%
Color and Shape:Soild
Molecular weight:430.89
Ref: TM-T84349
+ Info
NF546
CAS:
- 1006028-37-0
NF546 is a selective agonist of non-nucleotide P2Y11(pEC50 of 6.27).
Formula:C₄₇H₄₄N₆Na₄O₁₇P₄
Purity:98%
Color and Shape:Solid
Molecular weight:1180.74
Ref: TM-T12217
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Glucagon-like peptide 1 (1-37), human
CAS:
- 87805-34-3
Human GLP-1 (1-37) is a potent GLP-1 receptor agonist without impact on rat food intake or insulin secretion.
Formula:C₁₈₆H₂₇₅N₅₁O₅₉
Purity:98%
Color and Shape:Solid
Molecular weight:4169.48
Ref: TM-TP1148
+ Info
O-Desmethyl Mebeverine alcohol
CAS:
- 155172-67-1
Mebeverine metabolite O-desmethyl alcohol inhibits α1 receptors, relaxing the gut.
Formula:C₁₅H₂₅NO₂
Purity:98%
Color and Shape:Solid
Molecular weight:251.36
Ref: TM-T11989
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GLP-1(7-36), amide acetate
CAS:
- 1119517-19-9
GLP-1(7-36), amide acetate is a derivative of GLP-1 peptide , activate the GLP-1 receptor, promote insulin secretion,Type 2 diabetes mellitus and obesity.
Formula:C₁₅₁H₂₃₀N₄₀O₄₇
Purity:99.89%
Color and Shape:Solid
Molecular weight:3357.68
Ref: TM-TP1141
+ Info
JNJ-39933673
CAS:
- 1404307-42-1
JNJ-39933673 is a bio-active chemical.
Formula:C₄₈H₅₄F₂N₂O₁₁
Color and Shape:Solid
Molecular weight:872.96
Ref: TM-T32305
+ Info
Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].
Formula:C₁₉₃H₃₃₁F₃N₆₄O₅₅S₃
Color and Shape:Solid
Molecular weight:4581.28
Ref: TM-T75873