GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 19 more subcategories

Found 5838 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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Bradykinin (1-6)
CAS:
- 23815-88-5
Bradykinin (1-6) is a stable, CPY-cleaved metabolite that triggers pain, induces muscle contractions, and activates NO synthetase.
Formula:C₃₀H₄₅N₉O₈
Purity:98%
Color and Shape:Solid
Molecular weight:659.73
Ref: TM-TP1747
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(R)-V-0219 hydrochloride
(R)-V-0219 hydrochloride: Oral GLP-1R PAM, enantiomer of V-0219, triggers Ca2+ flux in hGLP-1R HEK cells.
Formula:C₂₀H₂₆ClF₃N₄O₂
Color and Shape:Solid
Molecular weight:446.89
Ref: TM-T74264
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MOR agonist-3
MOR agonist-3 (Compound 84) is a dual D3R/MOR antagonist with K i values of 382 nM and 55.2 nM, respectively.
Color and Shape:Odour Solid
Ref: TM-T81763
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CB1R agonist 1
CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.
Formula:C₂₀H₁₈F₃N₃O₃S
Color and Shape:Solid
Molecular weight:437.435
Ref: TM-T206337
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Cortistatin 14, human, rat acetate
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and
Formula:C₈₀H₁₁₂N₁₈O₁₉S₂
Purity:97.86%
Color and Shape:Solid
Molecular weight:1693.98
Ref: TM-TP1188L
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[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).
Formula:C₁₂₂H₂₁₀N₄₄O₃₇S
Purity:98.18%
Color and Shape:Solid
Molecular weight:2917.31
Ref: TM-TP1975L
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Synephrine hemitartrate
CAS:
- 16589-24-5
Synephrine hemitartrate, an alkaloid from Citrus aurantium, is a sympathomimetic for weight loss, with α and β-adrenergic action.
Formula:C₉H₁₃NO₂C₄H₆O₆
Color and Shape:Solid
Molecular weight:242.26
Ref: TM-T75425
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Surfagon
CAS:
- 52435-06-0
Surfagon is an effective LHRH agonist.
Formula:C₅₆H₇₈N₁₆O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1167.34
Ref: TM-T26239
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Antisauvagine-30 TFA
aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).
Formula:C₁₆₃H₂₇₅N₄₈F₃O₄₉S
Color and Shape:Solid
Molecular weight:3764.28
Ref: TM-T75805
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Amylin, amide, rat
CAS:
- 124447-81-0
Amylin: peptide, 50% similar to CGRP, found with somatostatin in stomach cells, reduces acid secretion in mice.
Formula:C₁₆₇H₂₇₂N₅₂O₅₃S₂
Purity:99.92%
Color and Shape:Solid
Molecular weight:3920.44
Ref: TM-TP1232
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GLP-1R agonist 4
CAS:
- 2401894-26-4
GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.
Formula:C₃₂H₃₀ClF₂N₃O₅
Color and Shape:Solid
Molecular weight:610.05
Ref: TM-T74323
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DSP-1053
CAS:
- 1176326-76-3
Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.
Formula:C₂₆H₃₂BrNO₄
Purity:98%
Color and Shape:Solid
Molecular weight:502.44
Ref: TM-T11107
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Preclamol hydrochloride
CAS:
- 88768-67-6
Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.
Formula:C₁₄H₂₂ClNO
Color and Shape:Solid
Molecular weight:255.78
Ref: TM-T73684
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LY86057
CAS:
- 148966-66-9
LY86057 is a bioactive chemical.
Formula:C₂₀H₂₆N₂O₃
Color and Shape:Solid
Molecular weight:342.439
Ref: TM-T33020
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15(S)-15-methyl Prostaglandin E2
CAS:
- 35700-27-7
15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.
Formula:C₂₁H₃₄O₅
Color and Shape:Solid
Molecular weight:366.49
Ref: TM-T36154
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AMI-193
CAS:
- 510-74-7
AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.
Formula:C₂₂H₂₆FN₃O₂
Purity:99.65%
Color and Shape:Solid
Molecular weight:383.46
Ref: TM-T21855
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Pirepemat
CAS:
- 1227638-29-0
Pirepemat (IRL752) is a cortical-preferring catecholamine agent that enhances cognition. It is utilized in the investigation of Parkinson's disease.
Formula:C₁₁H₁₃F₂NO
Color and Shape:Solid
Molecular weight:213.22
Ref: TM-T38610
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PF-232798
CAS:
- 849753-15-7
PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.
Formula:C₂₉H₄₀FN₅O₂
Color and Shape:Solid
Molecular weight:509.66
Ref: TM-T28381
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Tienoxolol FA
Tienoxolol FA, a beta-blocker for treating heart disease, hypertension, and ischemia.
Formula:C₂₂H₃₀N₂O₇S
Purity:97.05% - 98.53%
Color and Shape:Soild
Molecular weight:466.55
Ref: TM-T68161L
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(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.
Formula:C₂₉H₂₃F₆N₅O₃
Color and Shape:Solid
Molecular weight:603.52
Ref: TM-T73703
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S 16474
CAS:
- 149250-10-2
S 16474 is an antagonist of Neurokinin-1 Receptor.
Formula:C₄₄H₄₈N₆NaO₈
Purity:98%
Color and Shape:Solid
Molecular weight:811.892
Ref: TM-T26169
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GRL018-21
GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].
Color and Shape:Odour Solid
Ref: TM-T82258
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Prepro-ANF (56-92), human
CAS:
- 112199-06-1
Human prepro-ANF (56-92) activates renal guanylate cyclase and boosts its activity.
Formula:C₁₇₃H₂₇₀N₄₄O₅₇
Color and Shape:Solid
Molecular weight:3878.26
Ref: TM-T76389
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Histamine H4 receptor antagonist-1
CAS:
- 1246207-84-0
Histamine H4 receptor antagonist-1 is a potent antagonist of the histamine H4 receptor.
Formula:C₃₀H₃₈N₈O₂
Color and Shape:Solid
Molecular weight:542.68
Ref: TM-T38634
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INCB 3284 dimesylate
CAS:
- 887401-93-6
INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.
Formula:C₂₈H₃₉F₃N₄O₁₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:712.76
Ref: TM-T11647
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Linaclotide acetate
CAS:
- 851199-60-5
Linaclotide acetate, an oral guanylate cyclase C agonist with 14 amino acids, treats constipation-predominant IBS and chronic constipation.
Formula:C₆₁H₈₃N₁₅O₂₃S₆
Purity:98%
Color and Shape:Solid
Molecular weight:1586.79
Ref: TM-T11852L
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Imelciment
CAS:
- 2845128-03-0
Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.
Purity:95%
Color and Shape:Soild
Ref: TM-T9901A-366
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Protease-Activated Receptor-1 antagonist 2
CAS:
- 1454588-34-1
Orally active PAR-1 antagonist with 7 nM IC50; potential for CVD research.
Formula:C₂₄H₂₃F₂N₃O₂
Color and Shape:Solid
Molecular weight:423.46
Ref: TM-T74266
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Sufotidine
CAS:
- 80343-63-1
Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.
Formula:C₂₀H₃₁N₅O₃S
Purity:99.03% - 99.92%
Color and Shape:Solid
Molecular weight:421.56
Ref: TM-T68146
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Prolactin Releasing Peptide (1-31), human acetate
Prolactin Releasing Peptide (1-31), human (acetate), is a potent GPR10 ligand with high affinity, eliciting prolactin secretion.
Formula:C₁₆₂H₂₆N₅₆O₄₄S
Molecular weight:3724.17
Ref: TM-T78006
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PSB 0777 ammonium salt
CAS:
- 2122196-16-9
adenosine A2A receptor full agonist
Formula:C₁₈H₂₄N₆O₇S₂
Purity:98%
Color and Shape:Solid
Molecular weight:500.55
Ref: TM-T23196
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Cannabidiolic acid methyl ester
CAS:
- 55658-71-4
Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.
Formula:C₂₃H₃₂O₄
Color and Shape:Solid
Molecular weight:372.5
Ref: TM-T203571
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CB2R probe 1
CAS:
- 2634714-79-5
CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of
Formula:C₃₆H₄₂N₄O₄
Color and Shape:Solid
Molecular weight:594.74
Ref: TM-T74604
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GLP-2(1-33)(human)
CAS:
- 223460-79-5
GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.
Formula:C₁₆₅H₂₅₄N₄₄O₅₅S
Purity:98%
Color and Shape:Solid
Molecular weight:3766.19
Ref: TM-TP1157
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L-threo Lysosphingomyelin (d18:1)
CAS:
- 105615-55-2
L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).
Formula:C₂₃H₄₉N₂O₅P
Color and Shape:Solid
Molecular weight:464.62
Ref: TM-T38452
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12(S)-HpEPE
CAS:
- 103239-14-1
12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.
Formula:C₂₀H₃₀O₄
Color and Shape:Solid
Molecular weight:334.456
Ref: TM-T37968
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Poly-D-lysine hydrobromide (MW 1000-5000)
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.
Color and Shape:Odour Solid
Ref: TM-TCL-01108
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Tamuzimod
CAS:
- 2097854-81-2
Tamuzimod, an effective immunomodulator, exhibits modulatory activity on S1P Receptors with EC50 values below 1 μM [1] [2].
Formula:C₂₁H₁₃Cl₃F₃N₅O₃
Color and Shape:Solid
Molecular weight:546.71
Ref: TM-T74747
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Cloprostenol isopropyl ester
CAS:
- 157283-66-4
(+)-Chloprostol is a PGF2α agonist, mimics prostaglandin F2α, induces luteal dissolution in mares without side effects or stress.
Formula:C₂₅H₃₅ClO₆
Color and Shape:Solid
Molecular weight:466.99
Ref: TM-T29246
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5-HT2A receptor agonist-5
CAS:
- 2957888-63-8
5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.
Formula:C₂₃H₂₉N₃O
Color and Shape:Solid
Molecular weight:363.5
Ref: TM-T203649
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D5R agonist 1
D5R Agonist 1 (Compound 5j) is a selective, orally active partial agonist of the D5 receptor that can penetrate the blood-brain barrier (EC50: 269.7 nM). It has been demonstrated to enhance cognitive abilities in a scopolamine-induced amnesia model.
Color and Shape:Odour Solid
Ref: TM-T200501
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Haloperidol D4
CAS:
- 1189986-59-1
Haloperidol D4 is deuterium-labeled haloperidol.
Formula:C₂₁H₂₃ClFNO₂
Purity:98%
Color and Shape:Solid
Molecular weight:379.89
Ref: TM-T11535
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K-(D-1-Nal)-FwLL-NH2 TFA
K-(D-1-Nal)-FwLL-NH2 TFA: potent ghrelin inverse agonist; Ki=4.9 nM (COS7), 31 nM (HEK293T); blocks Gq/G13 signaling.
Formula:C₅₃H₆₈F₃N₉O₈
Color and Shape:Solid
Molecular weight:1016.16
Ref: TM-T75948
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Efranarelaxin alfa
CAS:
- 2969217-22-7
Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.
Color and Shape:Liquid
Ref: TM-T9901A-865
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HPP-9
HPP-9, a Proteolysis-Targeting Chimera (PROTAC) derived from Hedgehog Pathway Inhibitor-1 (HPI-1) with a pIC50 value of 6.71, is designed to degrade BET
Formula:C₄₉H₅₂N₆O₁₁
Color and Shape:Solid
Molecular weight:900.97
Ref: TM-T79907
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Val9-Oxytocin
CAS:
- 1021701-88-1
Val9-Oxytocin, an Oxytocin analog where Gly9 is substituted with Val9 [1], functions as a complete antagonist of the vasopressin (V1a) receptor.
Formula:C₄₆H₇₂N₁₂O₁₂S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1049.27
Ref: TM-T80136
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Nocistatin(human)
CAS:
- 212609-11-5
Blocker of nociceptin-induced allodynia and hyperalgesia
Formula:C₁₄₉H₂₃₈N₄₂O₅₃S₃
Purity:98%
Color and Shape:Solid
Molecular weight:3561.93
Ref: TM-TP2277
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6α-Prostaglandin I1
CAS:
- 62777-90-6
6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.
Formula:C₂₀H₃₄O₅
Color and Shape:Solid
Molecular weight:354.487
Ref: TM-T36238
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Xylamidine
CAS:
- 6443-50-1
Xylamidine is a biochemical.
Formula:C₁₉H₂₄N₂O₂
Color and Shape:Solid
Molecular weight:312.41
Ref: TM-T35195
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26Rfa, Hypothalamic Peptide, human
CAS:
- 600171-68-4
26RFa, a human neuropeptide, stimulates appetite and possibly regulates feeding and the gonadotropic axis, with ≈80% identity across human, rat, and frog.
Formula:C₁₂₇H₁₉₅N₃₇O₃₇
Purity:98%
Color and Shape:Solid
Molecular weight:2832.13
Ref: TM-TP1542
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PSA1 (141-150)
CAS:
- 160215-60-1
This Prostate Specific Antigen 1 peptide was used in the immunotherapy of cancer experiments.
Formula:C₅₅H₉₃N₁₃O₁₃S
Purity:98%
Color and Shape:Solid
Molecular weight:1176.47
Ref: TM-TP1493
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Galanin (1-19), human
CAS:
- 136005-51-1
Galanin (1-19), human: a fragment of GAL neuropeptide influencing hormone release, pain response, and eating behavior.
Formula:C₈₉H₁₃₀N₂₆O₂₅
Purity:98%
Color and Shape:Solid
Molecular weight:1964.14
Ref: TM-TP1529
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isomer-Cilansetron
CAS:
- 120635-77-0
isomer-Cilansetron is an isomer of Cilansetron.
Formula:C₂₀H₂₁N₃O
Purity:99.92% - 99.96%
Color and Shape:Soild
Molecular weight:319.4
Ref: TM-T27020L
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16,16-dimethyl Prostaglandin F2α
CAS:
- 39746-23-1
16,16-dimethyl Prostaglandin F2α can be used in related research in the field of life sciences. Its product number is T37993 and CAS number is 39746-23-1.
Formula:C₂₂H₃₈O₅
Color and Shape:Solid
Molecular weight:382.541
Ref: TM-T37993
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Mirtazapine N-oxide
CAS:
- 155172-12-6
Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.
Formula:C₁₇H₁₉N₃O
Color and Shape:Solid
Molecular weight:281.359
Ref: TM-T37430
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Mitemcinal fumarate
CAS:
- 154802-96-7
Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.
Formula:C₈₄H₁₄₂N₂O₂₈
Color and Shape:Solid
Molecular weight:1628.02
Ref: TM-T33402
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Neuronostatin-13 (human)
CAS:
- 1096485-24-3
Neuronostatin-13: human-conserved, 13-amino-acid peptide with amidated C-terminus.
Formula:C₆₄H₁₁₀N₂₀O₁₆
Purity:98%
Color and Shape:Solid
Molecular weight:1415.68
Ref: TM-TP1827
+ Info
1-Octadecyl Lysophosphatidic Acid
CAS:
- 52977-29-4
1-Octadecyl LPA, an LPA analog with stearic acid at sn-1, has strong platelet aggregation (EC50=9 nM) via G protein receptors.
Formula:C₂₁H₄₅O₆P
Color and Shape:Solid
Molecular weight:424.559
Ref: TM-T36768
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DOTA-EB-TATE
DOTA-EB-TATE is formed by combining the SST peptide derivative DOTA-octreotate with an Evans blue analog (EB). This peptide drug conjugate (PDC) enhances the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. Additionally, DOTA-EB-TATE serves in the synthesis/research of radiopharmaceutical conjugates (RDC).
Formula:C₁₀₅H₁₃₃N₂₁O₃₀S₅
Molecular weight:2329.63
Ref: TM-TP2996
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Prolactin-Releasing Peptide (12-31), rat
CAS:
- 222988-10-5
Prolactin-Releasing Peptide (12-31), rat, a fragment of PrRP, exhibits high affinity for GPR10 receptors and stimulates calcium mobilization in CHOK1 cells
Formula:C₁₀₄H₁₅₈N₃₂O₂₆
Molecular weight:2272.57
Ref: TM-T81391
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Neuropeptide Y (1-24) (human)
CAS:
- 131448-51-6
Neuropeptide Y (1-24) inhibits rat vas deferens twitch and activates NMDA-induced neurons in rat hippocampus.
Formula:C₁₁₆H₁₇₀N₃₀O₄₀S
Molecular weight:2656.83
Ref: TM-T76358
+ Info
Onvitrelin ucalontide
CAS:
- 1174415-90-7
Onvitrelin ucalontide is a LHRH analogue with anticancer effect; halts breast, ovarian, and prostate tumors in mice.
Formula:C₁₆₃H₂₄₃N₄₃O₃₂
Molecular weight:3316.94
Ref: TM-T76558
+ Info
Lintitript
CAS:
- 136381-85-6
Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.
Formula:C₂₀H₁₄ClN₃O₃S
Purity:99.28%
Color and Shape:Solid
Molecular weight:411.86
Ref: TM-T15759
+ Info
Sulamserod
CAS:
- 219757-90-1
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related
Formula:C₁₉H₂₈ClN₃O₅S
Purity:98.76%
Color and Shape:Solid
Molecular weight:445.96
Ref: TM-T13021
+ Info
(Iso)-Landipirdine
CAS:
- 1000308-09-7
(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.
Formula:C₁₈H₁₉FN₂O₃S
Purity:98.50%
Color and Shape:Soild
Molecular weight:362.42
Ref: TM-T27795L
+ Info
Petrelintide acetate
Petrelintide (ZP8396) acetate is an amylin analog with potential for weight reduction, suitable for diabetes research.
Formula:C₁₈₅H₃₀₅N₄₉O₆₁·xC₂H₄O₂
Color and Shape:Solid
Molecular weight:4191.69 (free base)
Ref: TM-TP3039
+ Info
CRSP-1
CAS:
- 697327-12-1
Central CT receptor agonist, 350x stronger than CT, no CGRP or adrenomedullin action, inhibits osteoclasts, affects rat feeding, body temp, and calcium.
Formula:C₁₇₅H₂₉₄N₅₄O₄₉S₅
Purity:98%
Color and Shape:Solid
Molecular weight:4098.88
Ref: TM-TP2049
+ Info
CHS-114
CHS-114 (SRF-114) is a fully human IgG1 antibody targeting the (CCR8) receptor. It shows potential for research in head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can be referred to as HumanIgG1kappa, Isotype Control.
Color and Shape:Odour Liquid
Ref: TM-T9901A-769
+ Info
3-hydroxy Desloratidine
CAS:
- 119410-08-1
3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.
Formula:C₁₉H₁₉ClN₂O
Color and Shape:Solid
Molecular weight:326.82
Ref: TM-T36119
+ Info
Glucagon Receptor Antagonist Inactive Control
CAS:
- 362482-00-6
Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences.
Formula:C₂₁H₂₃BrN₂OS
Color and Shape:Solid
Molecular weight:431.39
Ref: TM-T36580
+ Info
TE-8105
TE-8105 is a GLP-1 receptor agonist that demonstrates prolonged and enhanced efficacy in models of diabetes, obesity, and non-alcoholic steatohepatitis (NASH).
Color and Shape:Odour Solid
Ref: TM-TP3839
+ Info
APC 366 TFA
CAS:
- 2421110-28-1
APC 366 (TFA) is a potent irreversible inhibitor of mast cell tryptase. It is particularly useful in studies related to allergic diseases.
Formula:C₂₄H₂₉F₃N₆O₆
Color and Shape:Solid
Molecular weight:554.527
Ref: TM-T40081
+ Info
ALD1910
ALD1910 is a humanized monoclonal antibody targeting PACAP38 and PACAP27. It inhibits PACAP signaling through pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a non-linear epitope within PACAP and prevents its binding to cell surfaces. It is useful for studying PACAP-mediated migraines.
Color and Shape:Odour Liquid
Ref: TM-T9901A-1636
+ Info
Cannabigerorcinic Acid
CAS:
- 69734-83-4
Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.
Formula:C₁₈H₂₄O₄
Color and Shape:Solid
Molecular weight:304.386
Ref: TM-TN7556
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Selank
CAS:
- 129954-34-3
Selank is a synthetic analog of tuftsin.
Formula:C₃₃H₅₇N₁₁O₉
Purity:98%
Color and Shape:Solid
Molecular weight:751.87
Ref: TM-T20515
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Ethoxyquin Dimer
CAS:
- 74681-77-9
Ethoxyquin dimer is an antioxidant, metabolite of ethoxyquin, that protects fish meal/oil fats but can cause liver damage in mice.
Formula:C₂₈H₃₆N₂O₂
Color and Shape:Solid
Molecular weight:432.608
Ref: TM-T35620
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(±)5-iPF2α-VI
CAS:
- 179094-11-2
Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation.
Formula:C₂₀H₃₄O₅
Color and Shape:Solid
Molecular weight:354.487
Ref: TM-T36605
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mPGES-1/sEH-IN-1
mPGES-1/sEH-IN-1 (compound 1f) is an sEH inhibitor with an IC50 value of 5 μM. It also exhibits antitumor activity by inhibiting mPGES-1, with an IC50 value of 25 µM.
Formula:C₂₀H₁₆F₃N₃O₂
Color and Shape:Solid
Molecular weight:387.355
Ref: TM-T204923
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U92016A
CAS:
- 136924-88-4
U92016A is a highly potent and selective agonist of 5-HT1A receptor.
Formula:C₁₉H₂₅N₃
Purity:98%
Color and Shape:Solid
Molecular weight:295.42
Ref: TM-T29035
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Biotin-Gastrin Releasing Peptide, human TFA
Biotin-Gastrin Releasing Peptide, human TFA, is a biotinylated form of the gastrin-releasing peptide (GRP). GRP is a neuropeptide known for its growth-stimulating and tumorigenic properties.
Color and Shape:Odour Solid
Ref: TM-TP3746
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Bimatoprost cyclohexyl amide
Bimatoprostcyclohexyl amide (N-Cyclohexyl-desamethyl bimatoprost; 17-Phenyl trinor prostaglandin F2α cyclohexyl amide) is an analogue of Bimatoprost. This compound acts as an agonist of the prostaglandin F2α receptor (FP receptor) and can be utilized for research in lowering intraocular pressure and in studies of glaucoma.
Color and Shape:Odour Solid
Ref: TM-T211826
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Dabelotine, (R)-
CAS:
- 152886-02-7
Dabelotine, (R)- is the R-isomer of Dabelotine. Dabelotine is an adrenergic agonist used in the study of dementia.
Formula:C₁₅H₂₂N₂O₂
Color and Shape:Solid
Molecular weight:262.35
Ref: TM-T31176
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16-phenoxy tetranor Prostaglandin F2α
CAS:
- 51705-19-2
16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.
Formula:C₂₂H₃₀O₆
Color and Shape:Solid
Molecular weight:390.47
Ref: TM-T37995
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Msh (11-13)
CAS:
- 67727-97-3
Msh (11-13) is a bioactive chemical.
Formula:C₁₆H₃₀N₄O₄
Color and Shape:Solid
Molecular weight:342.43
Ref: TM-T33515
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HGS101
HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.
Color and Shape:Odour Liquid
Ref: TM-T9901A-1812
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CCK (26-31) (non-sulfated)
CAS:
- 89911-64-8
CCK (26-31) is a digestive, satiety-inducing, anxiety-related peptide fragment from CCK hormone in the brain and gut.
Formula:C₃₈H₅₀N₈O₁₀S₂
Molecular weight:842.98
Ref: TM-T37204
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Canine KP-10
Canine KP-10 is a potent kisspeptin that induces a significant gonadotropin and estradiol response in female dogs during estrus.
Color and Shape:Odour Solid
Ref: TM-TP3851
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GEP44
GEP44 is a peptide-biased triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), neuropeptide Y1 receptor (Y1-R), and neuropeptide Y2 receptor (Y2-R). It induces GLP-1R-dependent insulin secretion in rat and human islets by offsetting the actions of Y1-R and GLP-1R agonism, controlled by Y1-R antagonists. Additionally, GEP44 enhances glucose uptake in muscle tissue through Y1-R mediation independent of insulin and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 is utilized in studies related to obesity and type 2 diabetes.
Color and Shape:Odour Solid
Ref: TM-TP3915
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Vedaprofen
CAS:
- 71109-09-6
Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.
Formula:C₁₉H₂₂O₂
Purity:99.24% - 99.70%
Color and Shape:Solid
Molecular weight:282.38
Ref: TM-T36683
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GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.
Molecular weight:3850.31
Ref: TM-T75860
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TNP-ATP tetrasodium
TNP-ATP is an antagonist of purinergic P2Y1, P2X3, and P2X2/3 receptors, exhibiting IC50 values of 6, 0.9, and 7 nM, respectively, in HEK293 cells expressing human receptors. It reduces acetic acid-induced calcium flux in 1321N1 cells expressing P2X3 and P2X2/3 receptors with IC50 values of 100 and 62 nM, respectively. TNP-ATP also dose-dependently alleviates acetic acid-induced writhing responses in a visceral pain model in mice, with an ED50 of 6.35 µmol/kg.
Color and Shape:Odour Solid
Ref: TM-T211383
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Galanin (2-29) (rat)
CAS:
- 141696-11-9
Peptide agonist for galanin receptors
Formula:C₁₃₉H₂₀₈N₄₂O₄₀
Purity:98%
Color and Shape:Solid
Molecular weight:3107.4
Ref: TM-TP2251
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CB2 receptor antagonist 2
Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM.
Color and Shape:Odour Solid
Ref: TM-T82772
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Phendioxan
CAS:
- 130905-04-3
Phendioxan is a biochemcial.
Formula:C₂₅H₂₇NO₅
Color and Shape:Solid
Molecular weight:421.49
Ref: TM-T33971
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Somatostatin-25
CAS:
- 76461-17-1
Somatostatin: a brain/pancreas hormone binding receptors, with anxiolytic, antiepileptic, and appetite-suppressing effects.
Formula:C₁₂₇H₁₉₁N₃₇O₃₄S₃
Purity:98%
Color and Shape:Solid
Molecular weight:2876.3
Ref: TM-TP1810
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[D-p-Cl-Phe6,Leu17]-VIP
CAS:
- 102805-45-8
Selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors.
Formula:C₁₄₈H₂₃₉ClN₄₄O₄₂
Purity:98%
Color and Shape:Solid
Molecular weight:3342.24
Ref: TM-TP2103
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O-Desmethyl-N-deschlorobenzoyl Indomethacin
CAS:
- 50995-53-4
O-Desmethyl-N-deschlorobenzoyl indomethacin, a metabolite of indomethacin, reduces HL-60 cell viability and aids in synthesizing PGD2 receptor antagonists.
Formula:C₁₁H₁₁NO₃
Color and Shape:Solid
Molecular weight:205.213
Ref: TM-T36418
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15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
CAS:
- 1163135-96-3
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has
Formula:C₂₅H₃₅NO₄
Color and Shape:Solid
Molecular weight:413.558
Ref: TM-T35944
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Pemvidutide TFA
Pemvidutide (TFA), a GLP-1R/GCGR dual agonist, effectively reduces body weight, liver fat, and serum lipid levels, and is utilized in research on non-alcoholic
Formula:C₁₈₂H₂₇₅N₃₉O₅₄·xC₂HF₃O₂
Color and Shape:Solid
Molecular weight:3873.35 (free base)
Ref: TM-T78658
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(±)-4-hydroxy Propranolol β-D-Glucuronide
CAS:
- 94731-13-2
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol , which is a metabolite of propranolol.
Formula:C₂₂H₂₉NO₉
Color and Shape:Solid
Molecular weight:451.47
Ref: TM-T35402