GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5378 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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K-(D-1-Nal)-FwLL-NH2 TFA
K-(D-1-Nal)-FwLL-NH2 TFA: potent ghrelin inverse agonist; Ki=4.9 nM (COS7), 31 nM (HEK293T); blocks Gq/G13 signaling.
Formula:C₅₃H₆₈F₃N₉O₈
Color and Shape:Solid
Molecular weight:1016.16
Ref: TM-T75948
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IRL-1038
CAS:
- 144602-02-8
ETB endothelin receptor antagonist
Formula:C₆₈H₉₂N₁₄O₁₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1409.67
Ref: TM-TP2262
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KwFwLL-NH2
CAS:
- 942266-38-8
KwFwLL-NH2 is a hexapeptide that serves as a ligand for the ghrelin receptor (ghrelin receptor). This compound acts as a specific inverse agonist for the ghrelin receptor, exhibiting moderate potency (EC50=45.6 nM).
Formula:C₄₉H₆₆N₁₀O₆
Color and Shape:Solid
Molecular weight:891.11
Ref: TM-TP2863
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ALD1613
ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.
Color and Shape:Odour Liquid
Ref: TM-T9901A-967
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JNJ-10181457 (hydrochloride)
CAS:
- 544707-20-2
JNJ-10181457 (hydrochloride) is a non-imidazole H3 receptor antagonist that is brain-penetrating and selective, increasing NE and acetylcholine concentrations
Formula:C₂₀H₃₀Cl₂N₂O
Color and Shape:Solid
Molecular weight:385.37
Ref: TM-T37220
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Substance P (4-11)
CAS:
- 53749-60-3
Substance P (4-11), a C-terminal fragment of Substance P, acts as a highly selective agonist for NK1 receptors, demonstrating specificity in its interaction.
Formula:C₄₆H₆₇N₁₁O₁₀S
Color and Shape:Solid
Molecular weight:966.16
Ref: TM-T76455
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LP 12 hydrochloride
CAS:
- 1185136-22-4
LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).
Formula:C₃₂H₄₀ClN₃O
Color and Shape:Solid
Molecular weight:518.14
Ref: TM-T37073
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Prostaglandin F1α
CAS:
- 745-62-0
Prostaglandin F1α (PGF1α) is a lipid mediator and an endogenous metabolite of prostacyclin, regulate smooth muscle contraction.
Formula:C₂₀H₃₆O₅
Color and Shape:Solid
Molecular weight:356.5
Ref: TM-T37919
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TT-OAD2 free base
CAS:
- 1246826-07-2
TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.
Formula:C₅₀H₄₇Cl₂N₃O₆
Purity:98%
Color and Shape:Solid
Molecular weight:856.83
Ref: TM-T11406
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AZ7976
CAS:
- 2813866-27-0
AZ7976 (Compound 42), a potent and highly selective agonist for Relaxin Family Peptide Receptor 1 (RXFP1) with a pEC 50 value greater than 10.5, operates through an allosteric mechanism to enhance RXFP1's cAMP signaling, which physiologically elevates heart rate. This property makes AZ7976 a valuable tool in cardiovascular disease research [1].
Formula:C₃₀H₃₃F₇N₂O₆S
Color and Shape:Solid
Molecular weight:682.65
Ref: TM-T85783
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γ-1-Melanocyte Stimulating Hormone (MSH), amide
γ-1-Melanocyte Stimulating Hormone (MSH), amide, a peptide consisting of 11 amino acids, plays a critical role in regulating sodium (Na+) balance and blood
Formula:C₇₂H₉₇N₂₁O₁₄S
Color and Shape:Solid
Molecular weight:1512.9
Ref: TM-T75971
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FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.
Color and Shape:Solid
Molecular weight:3692.15
Ref: TM-T75859
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Guanylate cyclase-IN-1
CAS:
- 1361569-23-4
Guanylate cyclase-IN-1 (Example 46) is a specific inhibitor of guanylate cyclase, employed in research related to cardiovascular diseases.
Formula:C₂₀H₁₇FN₈O
Color and Shape:Solid
Molecular weight:404.409
Ref: TM-T38770
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REGN-7544
REGN-7544 is a humanised monoclonal antibody targeting NPR1, which blocks and inhibits NPR1 to increase blood pressure, hypotensione.
Purity:95%
Color and Shape:Odour Liquid
Ref: TM-T9901A-829
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GLP-1 receptor agonist 13
Compound (S)-9, a GLP-1 receptor agonist, exhibits an EC50 of 76 nM for the glucagon GLP-1 receptor [1].
Formula:C₂₅H₂₃ClF₂N₆O
Color and Shape:Solid
Molecular weight:496.94
Ref: TM-T79348
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Peptide YY (PYY) (3-36), porcine TFA
Peptide YY (PYY) (3-36), porcine TFA, functions as a gut hormone that serves as a Y2 receptor agonist, effectively reducing appetite [1].
Formula:C₁₇₆H₂₇₂N₅₂O₅₄·C₂HF₃O₂
Color and Shape:Solid
Molecular weight:4094.44
Ref: TM-T75773
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Atilmotin
CAS:
- 533927-56-9
Atilmotin is a gastrointestinal agent for treating motility disorders.
Formula:C₈₆H₁₃₅N₂₀O₁₉
Color and Shape:Solid
Molecular weight:1753.146
Ref: TM-T30199
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(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
CAS:
- 150646-45-0
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist known to counteract the inhibitory effects of IL-1a
Formula:C₁₅₉H₂₆₇N₄₉O₄₃
Color and Shape:Solid
Molecular weight:3553.12
Ref: TM-T76602
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Neuropeptide Y (2-36) (porcine)
CAS:
- 102961-52-4
Porcine Neuropeptide Y (2-36) is 97.14% similar to rat/human, an agonist for Y5, Y2, Y1 receptors, used in obesity research.
Formula:C₁₈₁H₂₇₈N₅₄O₅₅
Color and Shape:Solid
Molecular weight:4090.47
Ref: TM-T76356
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Pramlintide TFA
Pramlintide TFA, a polypeptide analogue of human amylin and an antidiabetic agent, exhibits antineoplastic properties in colorectal cancer [1].
Formula:C₁₇₃H₂₆₈N₅₁F₃O₅₅S₂
Color and Shape:Solid
Molecular weight:4063.4
Ref: TM-T75709
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Dexchlorpheniramine free base
CAS:
- 25523-97-1
Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
Formula:C₁₆H₁₉ClN₂
Purity:98%
Color and Shape:Oily Liquid Solid
Molecular weight:274.79
Ref: TM-T0785L
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[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
CAS:
- 68059-94-9
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a synthetic LHRH analog and a GnRH receptor antagonist.
Formula:C₆₇H₈₄N₁₆O₁₃
Color and Shape:Solid
Molecular weight:1321.48
Ref: TM-T76350
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NF546
CAS:
- 1006028-37-0
NF546 is a selective agonist of non-nucleotide P2Y11(pEC50 of 6.27).
Formula:C₄₇H₄₄N₆Na₄O₁₇P₄
Purity:98%
Color and Shape:Solid
Molecular weight:1180.74
Ref: TM-T12217
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Chemerin-9, Mouse
CAS:
- 686324-96-9
Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156.
Formula:C₅₁H₆₈N₁₀O₁₂
Color and Shape:Solid
Molecular weight:1013.163
Ref: TM-T37128
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Orforglipron hemicalcium hydrate
CAS:
- 3008544-96-2
Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) represents the hemicalcium hydrate form of the calcium salt of Orforglipron, an orally active agonist targeting the Glucagon-like peptide-1 receptor (GLP-1R). This compound has demonstrated efficacy in mitigating type 2 diabetes [1].
Formula:C₄₈H₄₈F₂N₁₀O₅Ca·H₂O
Color and Shape:Solid
Molecular weight:921.02
Ref: TM-T87071
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Angiopeptin TFA
CAS:
- 2478421-60-0
Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.
Formula:C₅₈H₇₃F₆N₁₁O₁₄S₂
Color and Shape:Solid
Molecular weight:1326.39
Ref: TM-T76042
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Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.
Formula:C₁₂₈H₂₁₆F₃N₄₅O₃₆S
Color and Shape:Solid
Molecular weight:3050.42
Ref: TM-T75925
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[Tyr11]-Somatostatin
CAS:
- 59481-27-5
[Tyr11]-Somatostatin, a neuroactive peptide, aids proteomics research and modulates retinal function.
Formula:C₇₆H₁₀₄N₁₈O₂₀S₂
Molecular weight:1653.89
Ref: TM-T40680
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Donetidine
CAS:
- 99248-32-5
Donetidine is a histamine H2 receptor antagonist used to treat digestive disorders.
Formula:C₂₀H₂₅N₅O₃S
Purity:99.32%
Color and Shape:Solid
Molecular weight:415.51
Ref: TM-T68056
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[Des-Arg10]-HOE I40 TFA
[Des-Arg10]-HOE I40 TFA is a potent antagonist of the bradykinin B1 receptor.
Formula:C₅₃H₇₇N₁₅O₁₂S·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T207446
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Adenosine 2',5'-diphosphate sodium
CAS:
- 154146-84-6
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors.
Formula:C₁₀H₁₅N₅NaO₁₀P₂
Color and Shape:Solid
Molecular weight:450.192
Ref: TM-T39025
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Sar-[D-Phe8]-des-Arg9-Bradykinin
CAS:
- 126959-88-4
Potent bradykinin B1 agonist, EC50 = 9.02 nM, enzyme resistant, induces hypotension and angiogenesis.
Formula:C₄₇H₆₆N₁₂O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:975.11
Ref: TM-TP1917
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Naratriptan D3 Hydrochloride
CAS:
- 1190021-64-7
Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.
Formula:C₁₇H₂₆ClN₃O₂S
Purity:98%
Color and Shape:Solid
Molecular weight:374.94
Ref: TM-T12176
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Mini Gastrin I, human
CAS:
- 54405-27-5
Mini Gastrin I, human, is a truncated form of the human gastrin peptide, encompassing amino acids 5-17 of the original sequence.
Formula:C₇₄H₉₉N₁₅O₂₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1646.73
Ref: TM-TP1821
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Satoreotide
CAS:
- 1801415-23-5
Satoreotide (JR11) is an SSTR2 antagonist, typically conjugated with radiolabeled chelators for use in neuroendocrine tumor imaging [1].
Formula:C₅₈H₇₂ClN₁₅O₁₄S₂
Color and Shape:Solid
Molecular weight:1302.87
Ref: TM-TP2620
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Spantide I
CAS:
- 91224-37-2
Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist.
Formula:C₇₅H₁₀₈N₂₀O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1497.79
Ref: TM-T20413
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Satavaptan
CAS:
- 185913-78-4
Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.
Formula:C₃₃H₄₅N₃O₈S
Color and Shape:Solid
Molecular weight:643.79
Ref: TM-T28664
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SAE-14
CAS:
- 1241280-25-0
GPR183, a chemotactic receptor aiding B cell maturation, binds 7α,25-OHC; studied in IBD research.
Formula:C₁₉H₁₉F₃N₂O₂
Purity:99.85%
Color and Shape:Solid
Molecular weight:364.36
Ref: TM-T9975
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ELA-11(human) TFA
ELA-11(human) TFA: apelin receptor agonist, K i =14 nM, inhibits cAMP, stimulates β-arrestin, from ELA-32 fragment.
Formula:C₆₀H₉₁F₃N₁₆O₁₅S₂
Color and Shape:Solid
Molecular weight:1397.58
Ref: TM-T76053
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BA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.
Formula:C₅₉H₇₇F₃N₁₄O₁₃
Color and Shape:Solid
Molecular weight:1247.32
Ref: TM-T75945
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GLP-1R agonist 19
CAS:
- 2765065-09-4
GLP-1R agonist 19 (M3190) is a potent, selective GLP-1 receptor agonist that demonstrates excellent plasma and liver microsomal stability, along with low hERG toxicity [1].
Formula:C₉₄H₁₃₆FN₂₁O₂₅
Color and Shape:Solid
Molecular weight:1979.21
Ref: TM-T86507
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[Nle13]-Motilin
CAS:
- 55524-56-6
[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1] [2] .
Formula:C₁₂₁H₁₉₀N₃₄O₃₅
Color and Shape:Solid
Molecular weight:2681.01
Ref: TM-T76359
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Cagrilintide acetate
.Cagrilintide is a long-acting amylin analog,treat diabetes and obesity by reducing appetite through activation of the AMY3R and calcitonin receptor.
Formula:C₁₉₆H₃₁₆N₅₄O₆₁S₂
Purity:99.88%
Color and Shape:Solid
Molecular weight:4469.06
Ref: TM-T76262L
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Rhazimine
CAS:
- 93772-08-8
Rhazimine is an indole alkaloid. It is a dual inhibitor of arachidonic acid metabolism and platelet activating factor-induced platelet aggregation.
Formula:C₂₁H₂₂N₂O₃
Color and Shape:Solid
Molecular weight:350.418
Ref: TM-T26072
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MM 07
CAS:
- 1876450-21-3
Biased agonist for apelin/G protein pathway, enhances eNOS and cell growth, reduces apoptosis, improves heart function, and dilates vessels.
Formula:C₆₇H₁₀₆N₂₂O₁₄S₃
Purity:98%
Color and Shape:Solid
Molecular weight:1539.9
Ref: TM-TP2000
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M1145
CAS:
- 1172089-00-7
Potent GAL2 agonist with EC50 = 38 nM; Ki: 6.55 nM (GAL2), 497 nM (GAL3), 587 nM (GAL1); enhances galanin signaling.
Formula:C₁₂₈H₂₀₅N₃₇O₃₂
Purity:98%
Color and Shape:Solid
Molecular weight:2774.26
Ref: TM-TP1991
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15(S)-HpEPE
CAS:
- 125992-60-1
15(S)-HpEPE, a monohydroperoxy fatty acid, forms when 15-lipoxygenase acts on EPA, with expected biological activities akin to 15(S)-HpETE.
Formula:C₂₀H₃₀O₄
Color and Shape:Solid
Molecular weight:334.456
Ref: TM-T37402
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CAY10606
CAS:
- 1159576-98-3
CAY10606 has a wide range of applications in life science related research.
Formula:C₂₂H₁₈ClNO₃
Color and Shape:Solid
Molecular weight:379.84
Ref: TM-T37353
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Adrenomedullin (AM) (22-52), human TFA
Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.
Formula:C₁₆₁H₂₅₃N₄₆F₃O₅₀
Purity:98%
Color and Shape:Solid
Molecular weight:3690.06
Ref: TM-TP1256
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Israpafant
CAS:
- 117279-73-9
Israpafant: PAF receptor blocker, IC50 0.84nM, hinders platelet aggregation, eosinophil activation, boosts calcium transit, anti-nephrotoxic.
Formula:C₂₈H₂₉ClN₄S
Color and Shape:Solid
Molecular weight:489.07
Ref: TM-T27638
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Pasireotide pamoate
CAS:
- 396091-79-5
Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.
Formula:C₈₁H₈₂N₁₀O₁₅
Purity:98%
Color and Shape:Solid
Molecular weight:1435.58
Ref: TM-T12369
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Neurokinin B (TFA)
CAS:
- 101536-55-4
Neurokinin B TFA, a tachykinin, targets NK1R, NK2R, nk3r GPCRs, modulating effects.
Formula:C₅₉H₈₁F₆N₁₃O₁₈S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1438.47
Ref: TM-TP1279
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BAY-747
CAS:
- 1609342-18-8
BAY-747: oral, brain-penetrant sGC stimulator; improves rat memory, cognition, lowers blood pressure, aids Duchenne muscular dystrophy.
Formula:C₂₂H₂₆F₂N₄O₂
Color and Shape:Solid
Molecular weight:416.46
Ref: TM-T75137
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PACAP (1-27), human, ovine, rat
CAS:
- 127317-03-7
PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
Formula:C₁₄₂H₂₂₄N₄₀O₃₉S
Purity:98%
Color and Shape:Solid
Molecular weight:3147.66
Ref: TM-TP1070
+ Info
Labradimil
CAS:
- 159768-75-9
Labradimil, a bradykinin B2 agonist, boosts brain drug delivery and tumor survival rates.
Formula:C₄₉H₇₅N₁₅O₁₂S
Purity:98%
Color and Shape:Solid
Molecular weight:1098.29
Ref: TM-T27790
+ Info
Kisspeptin 13
CAS:
- 374675-18-0
Kisspeptin 13 activates GPR54 & GnRH receptors, boosts memory, and aids in Alzheimer's research.
Formula:C₇₈H₁₀₇N₂₁O₁₈
Color and Shape:Solid
Molecular weight:1626.81
Ref: TM-T76339
+ Info
MRS2500 tetraammonium
CAS:
- 630103-23-0
Highly potent and selective antagonist of the platelet P2Y1 receptor
Formula:C₁₃H₂₁IN₆O₈P₂
Purity:98%
Color and Shape:Solid
Molecular weight:578.19
Ref: TM-T23023
+ Info
ECPLA
CAS:
- 2349367-50-4
ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.
Formula:C₂₁H₂₅N₃O
Color and Shape:Solid
Molecular weight:335.44
Ref: TM-T203569
+ Info
Upidosin
CAS:
- 152735-23-4
Upidosin (SB-216469), a uroselective α1 blocker: Ki α1a=0.34 nM, α1b=3.9 nM, α1d=1.5 nM, α2=33.3 nM.
Formula:C₃₁H₃₃N₃O₄
Purity:99.66%
Color and Shape:Solid
Molecular weight:511.61
Ref: TM-T9762
+ Info
YFLLRNP
CAS:
- 149440-16-4
YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.
Formula:C₄₅H₆₇N₁₁O₁₀
Color and Shape:Solid
Molecular weight:922.08
Ref: TM-T80235
+ Info
Orexin A (human, rat, mouse)
CAS:
- 205640-90-0
Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.
Formula:C₁₅₂H₂₄₃N₄₇O₄₄S₄
Purity:98%
Color and Shape:Solid
Molecular weight:3561.1
Ref: TM-TP1301
+ Info
PEN (rat)
CAS:
- 569364-13-2
PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
Formula:C₁₀₂H₁₆₉N₂₇O₃₃
Purity:98%
Color and Shape:Solid
Molecular weight:2301.62
Ref: TM-TP1951
+ Info
A3AR modulator 1
MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.
Formula:C₂₃H₂₅IN₄
Color and Shape:Solid
Molecular weight:484.38
Ref: TM-T74993
+ Info
TRAP-6 amide TFA
CAS:
- 1426807-16-0
TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.
Formula:C₃₆H₅₈F₃N₁₁O₁₀
Color and Shape:Solid
Molecular weight:861.922
Ref: TM-T38887
+ Info
LysoPalloT-NH-amide-C3-ph-m-O-C11
CAS:
- 1778686-61-5
LysoPalloT-NH-amide-C3-ph-m-O-C11 is an agonist of the GPR174 receptor with an EC50 value of 34 nM.
Formula:C₂₇H₄₇N₂O₉P
Color and Shape:Solid
Molecular weight:574.64
Ref: TM-T203412
+ Info
Motilin, canine
CAS:
- 85490-53-5
Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.
Formula:C₁₂₀H₁₉₄N₃₆O₃₄
Purity:98%
Color and Shape:Solid
Molecular weight:2685.05
Ref: TM-TP1098
+ Info
Tocrifluor T1117
CAS:
- 1186195-59-4
Fluorescent form of AM 251, CB1 receptor antagonist
Formula:C₅₆H₅₃Cl₂N₇O₅
Purity:98%
Color and Shape:Solid
Molecular weight:974.97
Ref: TM-T23464
+ Info
GIP/GLP-1 dual receptor agonist-1
CAS:
- 2807481-02-1
Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.
Color and Shape:Solid
Ref: TM-T75150
+ Info
Neuropeptide Y (13-36), amide, human
CAS:
- 122341-40-6
Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.
Formula:C₁₃₄H₂₀₇N₄₁O₃₆S
Purity:98%
Color and Shape:Solid
Molecular weight:3000.4
Ref: TM-TP1081
+ Info
ALEPH hydrochloride
CAS:
- 61638-08-2
ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.
Formula:C₁₂H₂₀ClNO₂S
Color and Shape:Solid
Molecular weight:277.81
Ref: TM-T203157
+ Info
Icatibant
CAS:
- 130308-48-4
Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively).
Formula:C₅₉H₈₉N₁₉O₁₃S
Purity:98%
Color and Shape:White Solid
Molecular weight:1304.52
Ref: TM-T15547
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Neuropeptide Y (22-36)
CAS:
- 119019-65-7
Neuropeptide Y (22-36) is a 15-amino acid fragment of NPY, which is abundant in the mammalian brain and involved in multiple physiological functions.
Formula:C₈₅H₁₃₉N₂₉O₂₁
Purity:98%
Color and Shape:Solid
Molecular weight:1903.19
Ref: TM-TP1681
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VU0453379 hydrochloride
VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.
Formula:C₂₆H₃₅ClN₄O₂
Color and Shape:Solid
Molecular weight:471.03
Ref: TM-T73840
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PF-4348235 HCl
PF-4348235 HCl (β2AR/M-receptor agonist-2 HCl) is a muscarinic M3 receptor antagonist (Ki: 0.73 nM) and β2 adrenergic receptor agonist (MABA, EC50: 3.7 nM). PF-4348235 HCl is also a bronchial BM213 acetate is a bronchodilator used to study cardiovascular and respiratory diseases such as chronic obstructive pulmonary disease (COPD).
Formula:C₃₆H₅₀Cl₂N₄O₇S
Purity:98.81%
Color and Shape:Solid
Molecular weight:753.78
Ref: TM-T72226L
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α-Helical CRF(9-41)
CAS:
- 90880-23-2
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
Formula:C₁₆₆H₂₇₄N₄₆O₅₃S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3827
Ref: TM-TP2048
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Peptide C105Y TFA
Peptide C105Y TFA is a cell-penetrating peptide synthesized based on the amino acid sequence of residues 359-374 of α1-antitrypsin. It enhances the gene expression of DNA nanoparticles.
Formula:C₉₇H₁₄₈N₂₀O₂₃S·xC₂HF₃O₂
Ref: TM-TP3340
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L-770644
CAS:
- 173901-95-6
L-770644 is an agonist of B3 adrenergic receptor.
Formula:C₃₀H₃₇N₇O₄S
Color and Shape:Solid
Molecular weight:591.72
Ref: TM-T24377
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ACTH (1-17)
CAS:
- 7266-47-9
ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.
Formula:C₉₅H₁₄₅N₂₉O₂₃S
Purity:98%
Color and Shape:Solid
Molecular weight:2093.41
Ref: TM-TP1011
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MCUF-651
CAS:
- 2747162-85-0
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
Formula:C₁₇H₂₂F₂N₄OS
Purity:99.83%
Color and Shape:Soild
Molecular weight:368.44
Ref: TM-T67734
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Myristoylated ARF6 (2-13)
Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.
Formula:C₇₄H₁₂₈N₁₆O₁₈
Molecular weight:1528.95925
Ref: TM-TP3490
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SGLT1/2-IN-2
CAS:
- 2387812-73-7
SGLT1/2-IN-2 is a chemical compound with robust dual inhibitory properties, exhibiting potent activities against SGLT1 (IC50 = 96 nM) and SGLT2 (IC50 = 1.3 nM).
Formula:C₂₃H₂₆F₂O₇
Color and Shape:Solid
Molecular weight:452.451
Ref: TM-T39966
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MK-0493 HCl
CAS:
- 455957-71-8
MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).
Formula:C₃₀H₃₉Cl₂F₂N₃O₂
Color and Shape:Solid
Molecular weight:582.55
Ref: TM-T33419
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Carazolol-d7
CAS:
- 1173021-02-7
Carazolol-d7 is the deuterium-labeled isotope of Carazolol, commonly used in pharmacokinetic studies to investigate the metabolic pathways of Carazolol.
Formula:C₁₈H₂₂N₂O₂
Color and Shape:Solid
Molecular weight:305.42
Ref: TM-T203713
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Leukotriene B5
CAS:
- 80445-66-5
LTB5, an eicosapentaenoic acid metabolite via 5-LO, has varied bioactivities and enhances bullfrog lung strip contraction.
Formula:C₂₀H₃₀O₄
Color and Shape:Solid
Molecular weight:334.456
Ref: TM-T36423
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Hemopressin(rat)
CAS:
- 568588-77-2
Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.
Formula:C₅₃H₇₇N₁₃O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1088.27
Ref: TM-TP1901
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Osanetant
CAS:
- 160492-56-8
Osanetant produces anxiolytic- and antidepressant-like effects. Osanetant is a selective NK3 receptor antagonist. It is researched for schizophrenia.
Formula:C₃₅H₄₁Cl₂N₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:606.62
Ref: TM-T16408
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Neuromedin N
CAS:
- 92169-45-4
Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
Formula:C₃₈H₆₃N₇O₈
Purity:98%
Color and Shape:Solid
Molecular weight:745.95
Ref: TM-TP1085
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Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.
Formula:C₁₉H₃₈ClN₅O₂S
Color and Shape:Solid
Molecular weight:436.06
Ref: TM-T75003
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MMC(TMZ)-TOC TFA
MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.
Formula:C₇₄H₉₉F₃N₂₀O₂₁S₂
Color and Shape:Solid
Molecular weight:1725.82
Ref: TM-T204151
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NI-203
NI-203 is a monoclonal antibody inhibitor that targets amylin and shows potential for research in type 2 diabetes.
Color and Shape:Odour Liquid
Ref: TM-T9901A-993
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Antisauvagine-30 TFA
aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).
Formula:C₁₆₃H₂₇₅N₄₈F₃O₄₉S
Color and Shape:Solid
Molecular weight:3764.28
Ref: TM-T75805
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Nolomirole
CAS:
- 90060-42-7
Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.
Formula:C₁₉H₂₇NO₄
Color and Shape:Solid
Molecular weight:333.42
Ref: TM-T33711
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Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.
Formula:C₂₂H₂₆FN₅O
Color and Shape:Solid
Molecular weight:395.47
Ref: TM-T74798
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Paynantheine
CAS:
- 4697-66-9
Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.
Formula:C₂₃H₂₈N₂O₄
Color and Shape:Solid
Molecular weight:396.48
Ref: TM-T203202
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FSLLRY-NH2
CAS:
- 245329-02-6
PAR2 antagonist; counters taxol effects, PKC in mice; inhibits ERK, collagen in fibroblasts; lessens dermatophyte itch in mice.
Formula:C₃₉H₆₀N₁₀O₈
Purity:98%
Color and Shape:Solid
Molecular weight:796.97
Ref: TM-TP1904
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L-803087 TFA
CAS:
- 1786412-46-1
L-803087 TFA: potent sst4 agonist, Ki=0.7 nM, >280x selective vs other somatostatin receptors; boosts AMPA, heightens seizures.
Formula:C₂₇H₃₀F₅N₅O₅
Color and Shape:Solid
Molecular weight:599.55
Ref: TM-T39207
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[Sar9] Substance P
CAS:
- 77128-75-7
[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
Formula:C₆₄H₁₀₀N₁₈O₁₃S
Purity:98%
Color and Shape:Solid
Molecular weight:1361.66
Ref: TM-TP1862
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Adrogolide HCl
CAS:
- 166591-11-3
Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.
Formula:C₂₂H₂₆ClNO₄S
Color and Shape:Solid
Molecular weight:435.96
Ref: TM-T29674
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[D-Trp34]-Neuropeptide Y
CAS:
- 153549-84-9
Potent NPY Y5 receptor agonist (pEC50 = 7.82); highly selective; induces hyperphagia, body weight gain; orally active.
Formula:C₁₉₆H₂₈₉N₅₅O₅₆
Purity:98%
Color and Shape:Solid
Molecular weight:4311.77
Ref: TM-TP1984
+ Info
GW-328267
CAS:
- 210237-78-8
GW-328267 is an agonist of the adenosine A2 receptor.
Formula:C₂₁H₂₆N₁₀O₄
Color and Shape:Solid
Molecular weight:482.5
Ref: TM-T24120