
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
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Metadoxine
CAS:<p>Metadoxine (Metadoxil) is a neurotransmitter stimulant.</p>Formula:C8H11NO3·C5H7NO3Purity:99.19%Color and Shape:Off-White PowderMolecular weight:298.29Talnetant hydrochloride
CAS:<p>Talnetant (SB 223412) hydrochloride, an NK3 antagonist, selectively binds hNK-3 at 1.4 nM, much less to hNK-2, none to hNK-1 at 100 μM.</p>Formula:C25H23ClN2O2Color and Shape:SolidMolecular weight:418.92PD 117519
CAS:<p>PD 117519 (CI947) is an agonist of adenosine receptor</p>Formula:C19H21N5O4Purity:99.98%Color and Shape:SolidMolecular weight:383.4Poloxamer 407
CAS:<p>Poloxamer 407 is a nonionic surfactant.</p>Purity:98%Color and Shape:White Crystalline PowderMolecular weight:7700(Average)Decynium 22
CAS:<p>Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor</p>Formula:C23H23IN2Purity:99.92%Color and Shape:Dark Red CrystalsMolecular weight:454.35Aripiprazole monohydrate
CAS:<p>Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.</p>Formula:C23H29Cl2N3O3Color and Shape:SolidMolecular weight:466.4Tandospirone hydrochloride
CAS:<p>Tandospirone (SM-3997) HCl: potent 5-HT1A partial agonist; Ki: 27 nM; anxiolytic, antidepressant, for CNS disorder research.</p>Formula:C21H30ClN5O2Color and Shape:SolidMolecular weight:419.95Clozapine HCl
CAS:<p>Clozapine HCl, an atypical antipsychotic, binds CNS receptors, targets 5-HT2A/2C, has weaker D2 antagonism. Risk: Agranulocytosis.</p>Formula:C18H20Cl2N4Color and Shape:SolidMolecular weight:363.29ML-191
CAS:<p>ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.</p>Formula:C24H25N3O3Purity:99.58%Color and Shape:SolidMolecular weight:403.47Bavisant dihydrochloride hydrate
CAS:Bavisant dihydrochloride (JNJ31001074AAC) is an oral H3 receptor antagonist for ADHD treatment. Phase 2 trials show no significant benefits at 10 mg/day.Formula:C19H31Cl2N3O3Color and Shape:SolidMolecular weight:420.38Quipazine
CAS:<p>Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.</p>Formula:C13H15N3Color and Shape:SolidMolecular weight:213.28Brefonalol
CAS:<p>Brefonalol is a vasodilating beta-adrenergic receptor blocker.</p>Formula:C22H28N2O2Color and Shape:SolidMolecular weight:352.47Raclopride tartrate
CAS:<p>Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM).</p>Formula:C19H26Cl2N2O9Color and Shape:SolidMolecular weight:497.32RU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formula:C18H22N2O5Color and Shape:SolidMolecular weight:346.38Midaglizole
CAS:<p>Midaglizole, an α2-adrenoceptor blocker, raises blood pressure and lowers glucose.</p>Formula:C16H17N3Color and Shape:SolidMolecular weight:251.33Cangrelor free acid
CAS:<p>Cangrelor, a reversible P2Y12 inhibitor for IV use, was approved in June 2015; it rapidly blocks ADP-induced platelet aggregation.</p>Formula:C17H25Cl2F3N5O12P3S2Color and Shape:SolidMolecular weight:776.36Eltoprazine dihydrochloride
CAS:<p>Eltoprazine dihydrochloride, a drug developed for aggression, is now studied for L-DOPA-induced dyskinesia in Parkinson's.</p>Formula:C12H18Cl2N2O2Purity:99.64%Color and Shape:SolidMolecular weight:293.194-Methylhistamine hydrochloride
CAS:<p>Compound with imidazole ring & amine group; inhibits copper enzymes, affects gene expression.</p>Formula:C6H12ClN3Purity:95%Color and Shape:SolidMolecular weight:161.633Butyrophenone
CAS:<p>Butyrophenone (NSC-8463) is a chemical compound. Some of its derivatives are used to treat various psychiatric disorders.</p>Formula:C10H12OPurity:99.84%Color and Shape:Colourless To Yellow LiquidMolecular weight:148.2BCTC
CAS:<p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>Formula:C20H25ClN4OPurity:99.21%Color and Shape:SolidMolecular weight:372.89
