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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

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  • Metadoxine

    CAS:
    <p>Metadoxine (Metadoxil) is a neurotransmitter stimulant.</p>
    Formula:C8H11NO3·C5H7NO3
    Purity:99.19%
    Color and Shape:Off-White Powder
    Molecular weight:298.29
  • Talnetant hydrochloride

    CAS:
    <p>Talnetant (SB 223412) hydrochloride, an NK3 antagonist, selectively binds hNK-3 at 1.4 nM, much less to hNK-2, none to hNK-1 at 100 μM.</p>
    Formula:C25H23ClN2O2
    Color and Shape:Solid
    Molecular weight:418.92
  • PD 117519

    CAS:
    <p>PD 117519 (CI947) is an agonist of adenosine receptor</p>
    Formula:C19H21N5O4
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:383.4
  • Poloxamer 407

    CAS:
    <p>Poloxamer 407 is a nonionic surfactant.</p>
    Purity:98%
    Color and Shape:White Crystalline Powder
    Molecular weight:7700(Average)
  • Decynium 22

    CAS:
    <p>Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor</p>
    Formula:C23H23IN2
    Purity:99.92%
    Color and Shape:Dark Red Crystals
    Molecular weight:454.35
  • Aripiprazole monohydrate

    CAS:
    <p>Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.</p>
    Formula:C23H29Cl2N3O3
    Color and Shape:Solid
    Molecular weight:466.4
  • Tandospirone hydrochloride

    CAS:
    <p>Tandospirone (SM-3997) HCl: potent 5-HT1A partial agonist; Ki: 27 nM; anxiolytic, antidepressant, for CNS disorder research.</p>
    Formula:C21H30ClN5O2
    Color and Shape:Solid
    Molecular weight:419.95
  • Clozapine HCl

    CAS:
    <p>Clozapine HCl, an atypical antipsychotic, binds CNS receptors, targets 5-HT2A/2C, has weaker D2 antagonism. Risk: Agranulocytosis.</p>
    Formula:C18H20Cl2N4
    Color and Shape:Solid
    Molecular weight:363.29
  • ML-191

    CAS:
    <p>ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.</p>
    Formula:C24H25N3O3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:403.47
  • Bavisant dihydrochloride hydrate

    CAS:
    Bavisant dihydrochloride (JNJ31001074AAC) is an oral H3 receptor antagonist for ADHD treatment. Phase 2 trials show no significant benefits at 10 mg/day.
    Formula:C19H31Cl2N3O3
    Color and Shape:Solid
    Molecular weight:420.38
  • Quipazine

    CAS:
    <p>Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.</p>
    Formula:C13H15N3
    Color and Shape:Solid
    Molecular weight:213.28
  • Brefonalol

    CAS:
    <p>Brefonalol is a vasodilating beta-adrenergic receptor blocker.</p>
    Formula:C22H28N2O2
    Color and Shape:Solid
    Molecular weight:352.47
  • Raclopride tartrate

    CAS:
    <p>Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM).</p>
    Formula:C19H26Cl2N2O9
    Color and Shape:Solid
    Molecular weight:497.32
  • RU 24969 succinate

    CAS:
    <p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>
    Formula:C18H22N2O5
    Color and Shape:Solid
    Molecular weight:346.38
  • Midaglizole

    CAS:
    <p>Midaglizole, an α2-adrenoceptor blocker, raises blood pressure and lowers glucose.</p>
    Formula:C16H17N3
    Color and Shape:Solid
    Molecular weight:251.33
  • Cangrelor free acid

    CAS:
    <p>Cangrelor, a reversible P2Y12 inhibitor for IV use, was approved in June 2015; it rapidly blocks ADP-induced platelet aggregation.</p>
    Formula:C17H25Cl2F3N5O12P3S2
    Color and Shape:Solid
    Molecular weight:776.36
  • Eltoprazine dihydrochloride

    CAS:
    <p>Eltoprazine dihydrochloride, a drug developed for aggression, is now studied for L-DOPA-induced dyskinesia in Parkinson's.</p>
    Formula:C12H18Cl2N2O2
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:293.19
  • 4-Methylhistamine hydrochloride

    CAS:
    <p>Compound with imidazole ring &amp; amine group; inhibits copper enzymes, affects gene expression.</p>
    Formula:C6H12ClN3
    Purity:95%
    Color and Shape:Solid
    Molecular weight:161.633
  • Butyrophenone

    CAS:
    <p>Butyrophenone (NSC-8463) is a chemical compound. Some of its derivatives are used to treat various psychiatric disorders.</p>
    Formula:C10H12O
    Purity:99.84%
    Color and Shape:Colourless To Yellow Liquid
    Molecular weight:148.2
  • BCTC

    CAS:
    <p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>
    Formula:C20H25ClN4O
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:372.89