
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,998 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(40 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5959 products of "GPCR/G-Protein"
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Plecanatide
CAS:Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.Formula:C65H104N18O26S4Purity:97.51%Color and Shape:SolidMolecular weight:1681.89Etrasimod
CAS:Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).Formula:C26H26F3NO3Purity:98.52% - 99.73%Color and Shape:SolidMolecular weight:457.48Ref: TM-TQ0227
1mg50.00€5mg105.00€10mg170.00€25mg230.00€50mg289.00€100mg401.00€1mL*10mM (DMSO)107.00€Vanoxerine dihydrochloride
CAS:Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)Formula:C28H34Cl2F2N2OPurity:98.16% - 98.35%Color and Shape:White SolidMolecular weight:523.49CCG215022
CAS:CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.Formula:C26H22FN7O3Purity:97.63% - 99.69%Color and Shape:SolidMolecular weight:499.5Ref: TM-T3498
1mg56.00€5mg114.00€10mg178.00€25mg394.00€50mg655.00€100mg1,035.00€1mL*10mM (DMSO)127.00€Clemizole hydrochloride
CAS:Clemizole hydrochloride blocks H1 histamine receptors and inhibits HCV replication and NS4B RNA binding.Formula:C19H21Cl2N3Purity:>99.99%Color and Shape:SolidMolecular weight:362.3Hemopressin (rat) acetate(568588-77-2 free base)
Hemopressin is a nonapeptide, CB2 agonist, derived from rat hemoglobin, with antinociceptive properties.Formula:C5H81N13O14Purity:99.37%Color and Shape:SolidMolecular weight:1148.31LY 78335
CAS:LY 78335 (1-(2,3-Dichlorophenyl)ethanamine hydrochloride) is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.Formula:C8H10Cl3NPurity:99.30% - 99.81%Color and Shape:SolidMolecular weight:226.53Norepinephrine bitartrate salt
CAS:Norepinephrine bitartrate salt is an adrenergic neurotransmitter.Formula:C12H17NO9Purity:97.32% - 99.97%Color and Shape:SolidMolecular weight:319.27BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Formula:C25H40N8O2Purity:99.66% - 99.79%Color and Shape:SolidMolecular weight:484.64Ref: TM-T4584
1mg63.00€5mg137.00€10mg187.00€25mg341.00€50mg567.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)145.00€4i
CAS:4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.Formula:C16H12ClN3OPurity:99.49%Color and Shape:SolidMolecular weight:297.74Mecamylamine
CAS:Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.Formula:C11H21NColor and Shape:SolidMolecular weight:167.29CRF (6-33) acetate(120066-38-8 free base)
CRFBP inhibitor peptide; reduces weight gain, boosts activity in obese rats.Formula:C143H235N41O45SPurity:97.12%Color and Shape:SolidMolecular weight:3280.76Bepotastine Besilate
CAS:Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).Formula:C21H25ClN2O3·C6H6O3SPurity:99.83% - 99.9%Color and Shape:Brown Viscous LiquidMolecular weight:547.06BAY 41-8543
CAS:BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
Formula:C21H21FN8OPurity:99.86%Color and Shape:SolidMolecular weight:420.44Zacopride hydrochloride
CAS:Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.Formula:C15H20ClN3O2·HClPurity:98.32%Color and Shape:SolidMolecular weight:346.26Ref: TM-T5336
1mg34.00€5mg71.00€10mg99.00€25mg212.00€50mg385.00€100mg618.00€200mg859.00€1mL*10mM (DMSO)79.00€RO1138452
CAS:RO1138452 (CAY10441) blocks prostacyclin receptor; orally active, high affinity (Ki: 1.5 nM), analgesic in rats (2-20 mg/kg).Formula:C19H23N3OPurity:97.01% - 99.34%Color and Shape:SolidMolecular weight:309.41Ref: TM-T4436
1mg49.00€2mg65.00€5mg90.00€10mg144.00€25mg313.00€50mg537.00€100mg767.00€1mL*10mM (DMSO)90.00€TNCA
CAS:TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.Formula:C12H12N2O2Purity:97.33% - 97.73%Color and Shape:SolidMolecular weight:216.24Clobenpropit 2HBr
CAS:Clobenpropit 2HBr is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain.Formula:C14H17ClN4SColor and Shape:SolidMolecular weight:308.83BRL-15572 dihydrochloride
CAS:BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.Formula:C25H27ClN2O·2HClPurity:99.74%Color and Shape:SolidMolecular weight:479.87Xaliproden hydrochloride
CAS:Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.Formula:C24H23ClF3NPurity:99.99%Color and Shape:SolidMolecular weight:417.89Ref: TM-T9272
1mg38.00€5mg80.00€10mg114.00€25mg222.00€50mg356.00€100mg512.00€200mg735.00€1mL*10mM (DMSO)92.00€
