GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5745 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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NCGC00135472
CAS:
- 862811-76-5
NCGC00135472: DRV1 agonist with pro-catabolic effects, activates DRV1/GPR32, EC50: 0.37 uM (beta-blocker), 0.05 uM (cAMP), enhances phagocytosis.
Formula:C₂₀H₁₄F₂N₄O
Purity:99.41% - 99.48%
Color and Shape:Solid
Molecular weight:364.35
Ref: TM-T33613
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R 59-022 hydrochloride
CAS:
- 93076-98-3
R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formula:C₂₇H₂₇ClFN₃OS
Purity:97.7%
Color and Shape:Solid
Molecular weight:496.04
Ref: TM-T72322
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N-[(4-Aminophenyl)methyl]adenosine
CAS:
- 95523-13-0
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).
Formula:C₁₇H₂₀N₆O₄
Purity:98.75%
Color and Shape:Solid
Molecular weight:372.38
Ref: TM-T16166
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ADR-851 free base
CAS:
- 138559-56-5
ADR-851 free base is an antagonist of the HT3 receptor.
Formula:C₁₄H₁₈ClN₃O₂
Purity:97.88% - 98.39%
Color and Shape:Solid
Molecular weight:295.77
Ref: TM-T23642
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RS 67333 hydrochloride
CAS:
- 168986-60-5
RS 67333 hydrochloride is a selective 5-HT4R partial agonist (pKi=8.7) with neuroprotective properties for Alzheimer's research.
Formula:C₁₉H₃₀Cl₂N₂O₂
Purity:98.78%
Color and Shape:Solid
Molecular weight:389.36
Ref: TM-T23265
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Compound C108
CAS:
- 15533-09-2
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).
Formula:C₁₅H₁₄N₂O₃
Purity:99.77%
Color and Shape:Solid
Molecular weight:270.28
Ref: TM-T38387
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5HT6-ligand-1
CAS:
- 1038988-11-2
5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).
Formula:C₂₀H₂₂BrN₃O₂S
Purity:99.24% - 99.93%
Color and Shape:Solid
Molecular weight:448.38
Ref: TM-T10053
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GP2-114
CAS:
- 130783-39-0
GP2-114 is a catecholamine motility mimetic that produces current-dependent cardiovascular effects.Cost-effective and quality-assured.
Formula:C₁₉H₂₄N₂O₄
Purity:99.32%
Color and Shape:Solid
Molecular weight:344.4
Ref: TM-T19345
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PF-00217830
CAS:
- 846032-02-8
PF-00217830: agonist at serotonin 1A & dopamine D2, antagonist at serotonin 2A, potential schizophrenia study drug.
Formula:C₂₆H₃₀N₄O₂
Purity:98.72%
Color and Shape:Solid
Molecular weight:430.54
Ref: TM-T24613
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SC 19220
CAS:
- 19395-87-0
SC 19220 is a prostaglandin E2 receptor EP1 antagonist that inhibits RANKL-induced osteoclastogenesis.
Formula:C₁₆H₁₄ClN₃O₃
Purity:98%
Color and Shape:Solid
Molecular weight:331.75
Ref: TM-T23330
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AZ-1355
CAS:
- 75451-07-9
AZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties.
Formula:C₁₇H₁₇NO₄
Purity:99.81%
Color and Shape:Solid
Molecular weight:299.32
Ref: TM-T13563
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Runcaciguat
CAS:
- 1402936-61-1
Runcaciguat, a soluble guanylate cyclase stimulator, aids in cardiovascular and renal research.
Formula:C₂₃H₂₂Cl₂F₃NO₃
Purity:99.17%
Color and Shape:Solid
Molecular weight:488.33
Ref: TM-T16808
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Masilukast
CAS:
- 136564-68-6
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation.
Formula:C₃₁H₃₂F₃N₃O₅S
Purity:99.23% - 99.62%
Color and Shape:Solid
Molecular weight:615.66
Ref: TM-T27979
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Proxyfan
CAS:
- 177708-09-7
Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.
Formula:C₁₃H₁₆N₂O
Purity:99.68%
Color and Shape:Solid
Molecular weight:216.28
Ref: TM-T23190
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Felcisetrag
CAS:
- 916075-84-8
Felcisetrag (TD-8954), an oral 5-HT4 agonist with GI prokinetic effects, has a high affinity (pKi 9.4) for h5-HT4(c) receptors.
Formula:C₂₅H₃₇N₅O₃
Purity:99.99%
Color and Shape:Solid
Molecular weight:455.59
Ref: TM-T28934
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MRS1220
CAS:
- 183721-15-5
MRS1220, a selective and potent antagonist for the human A3 adenosine receptor (hA3AR) with a dissociation constant (Ki) of 0.59 nM, exhibits therapeutic
Formula:C₂₁H₁₄ClN₅O₂
Purity:98.43%
Color and Shape:Solid
Molecular weight:403.82
Ref: TM-T23016
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PNU-282987 free base
CAS:
- 711085-63-1
PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.
Formula:C₁₄H₁₇ClN₂O
Purity:99.64%
Color and Shape:Solid
Molecular weight:264.75
Ref: TM-T60437
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Abt-288
CAS:
- 948845-91-8
ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.
Formula:C₂₃H₂₄N₄O
Purity:98.17% - 98.49%
Color and Shape:Solid
Molecular weight:372.46
Ref: TM-T26526
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APNEA
CAS:
- 89705-21-5
APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) is a non-selective agonist of adenosine A3 receptor.
Formula:C₁₈H₂₂N₆O₄
Purity:99.88%
Color and Shape:Solid
Molecular weight:386.41
Ref: TM-T12159
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Agomelatine hydrochloride
CAS:
- 1176316-99-6
Agomelatine HCl is a MT1/MT2 receptor agonist (Ki: 0.1-0.27 nM) and a 5-HT2C antagonist (pKi: 6.2-6.4).
Formula:C₁₅H₁₈ClNO₂
Purity:99.57%
Color and Shape:Solid
Molecular weight:279.76
Ref: TM-T60523