GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,997 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(40 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5958 products of "GPCR/G-Protein"
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Prostaglandin E2-1-glyceryl ester
CAS:Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Formula:C23H38O7Color and Shape:SolidMolecular weight:426.55Tradipitant
CAS:Tradipitant (VLY-686) is an antagonist of neurokinin-1.Formula:C28H16ClF6N5OPurity:99.42%Color and Shape:SolidMolecular weight:587.9Ref: TM-T17156
1mg60.00€2mg85.00€5mg119.00€10mg187.00€25mg329.00€50mg490.00€100mg700.00€1mL*10mM (DMSO)157.00€(1S)-CCR2 antagonist 1
CAS:(1S)-CCR2 antagonist 1, a left-handed chiral form of CCR2 antagonist 1, exhibits high affinity and a long residence time as a CCR2 antagonist, with an inhibition constant (K i) of 2.4 nM [1].Formula:C28H32BrF3N2OColor and Shape:SolidMolecular weight:549.47UCB-35440
CAS:UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.Formula:C31H34ClN5O4Color and Shape:SolidMolecular weight:576.09URB447
CAS:URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].Formula:C25H21ClN2OColor and Shape:SolidMolecular weight:400.9FAUC-312
CAS:FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.Formula:C21H26N4Purity:98%Color and Shape:SolidMolecular weight:334.46Prostaglandin F2α 1,9-lactone
CAS:Prostaglandin F2α (PGF2α) 1,9-lactone, a lipid-soluble internal ester of PGF2α, demonstrates resistance to hydrolysis by human plasma esterases, maintaining its structure even after 20 hours of incubation under physiological conditions. Unlike PGF2α, this compound exhibits minimal antifertility and vasoactivity.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.5Cipralisant
CAS:Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.Formula:C14H20N2Purity:98%Color and Shape:SolidMolecular weight:216.32BMY-42393
CAS:BMY-42393 is an oral prostacyclin agonist and platelet aggregation inhibitor with IC50 of 0.3-2μM and stimulates adenylate cyclase (EC50 = 25nM).Formula:C25H21NO4Color and Shape:SolidMolecular weight:399.44GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Formula:C19H29FN4O8S2Purity:98%Color and Shape:SolidMolecular weight:524.58(15R)-Bimatoprost
CAS:"(15R)-Bimatoprost (15(R)-17-phenyl trinor PGF2α ethyl amide), an isomer of Bimatoprost characterized by an inverted (β) hydroxyl group on C-15 [1], is a prostaglandin analog employed in the treatment of glaucoma and ocular hypertension."Formula:C25H37NO4Color and Shape:SolidMolecular weight:415.57LM-1484
CAS:LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.Formula:C28H24N4O3Purity:98%Color and Shape:SolidMolecular weight:464.52BMS-870145
CAS:BMS-870145 is a potent and selective P2Y1 purinergic receptor antagonist..Formula:C30H24ClF4N3O3Color and Shape:SolidMolecular weight:585.98Amauromine
CAS:Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.Formula:C32H36N4O2Color and Shape:SolidMolecular weight:508.65SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Formula:C18H30N2O2SPurity:99.73%Color and Shape:SolidMolecular weight:338.51Ref: TM-T12855
2mg34.00€5mg52.00€10mg85.00€25mg155.00€50mg240.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)58.00€Prostaglandin E2 Ethanolamide
CAS:Prostaglandin E2 Ethanolamide (PGE 2 -EA), an analog of PGE2, is enzymatically synthesized through COX-2 oxygenation of endocannabinoids. It has the potential to modulate the production of the proinflammatory cytokine TNF-α in human blood and monocytic cells [1] [2].Formula:C22H37NO5Color and Shape:SolidMolecular weight:395.54RXFP1 receptor agonist-6
CAS:RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably expressFormula:C38H32F5N3O7Color and Shape:SolidMolecular weight:737.678-iso-15(R)-Prostaglandin F2α
CAS:8-iso-15(R)-Prostaglandin F2α (8-iso-15(R) PGF2α) is a chemically distinct member within a broad group of prostaglandin-like eicosanoids, produced through the free radical peroxidation of arachidonic acid contained in membrane phospholipids. It represents the C-15 epimer of 8-isoPGF2α, distinguished as the sole isoprostane isomer extensively examined across numerous biological systems.Formula:C20H34O5Color and Shape:SolidMolecular weight:354.5GPR3 agonist-2
CAS:GPR3 agonist-2 (compound 32) is a potent full agonist of the G protein-coupled receptor 3 (GPR3), exhibiting an IC50 value of 260 nM [1].Formula:C14H7F6IO4SColor and Shape:SolidMolecular weight:512.16Tianagliflozin
CAS:Tianagliflozin, a sodium/glucose cotransporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.Formula:C21H25ClO5Purity:98%Color and Shape:SolidMolecular weight:392.87
