GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,029 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(61 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6012 products of "GPCR/G-Protein"
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CGRP antagonist 7
CAS:CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.Formula:C30H32FN5O3Color and Shape:SolidMolecular weight:529.61NK1 receptor antagonist 2
CAS:NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.Formula:C31H35F7N4O2Color and Shape:SolidMolecular weight:628.62BW A868C
CAS:BW A868C is a potent, selective PGD2 antagonist and a BW245C analogue, inert to other prostaglandin receptors.Formula:C25H37N3O5Color and Shape:SolidMolecular weight:459.58Quinagolide Free Base
CAS:Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.Formula:C20H33N3O3SColor and Shape:SolidMolecular weight:395.56SPL-IN-1
CAS:SPL-IN-1 (compound C17) acts as a dual species inhibitor of sphingosine-1-phosphate lyase [1].Formula:C31H42N2O6S2Color and Shape:SolidMolecular weight:602.8(S)-Bucindolol
CAS:(S)-Bucindolol is an enantiomer of bucindolol, specifically a β1-adrenergic receptor antagonist. It is primarily utilized in research related to heart failure.Formula:C22H25N3O2Color and Shape:SolidMolecular weight:363.45Dopamine D4 receptor ligand 3
CAS:Dopamine D4 receptor ligand 3 (Compound 16) functions as a dopamine D4 receptor (D4R) antagonist with a pKi of 8.86. In HEK-293T cells, it shows pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and βArr2 sensors, respectively. This compound inhibits the activity of human glioma cell lines U87 MG, T98G, and U251 MG, and it induces ROS production and mitochondrial dysfunction in these glioma cells.Formula:C28H31N3O5Color and Shape:SolidMolecular weight:489.56NK-1 Antagonist 1
CAS:NK-1 Antagonist 1 is a NK-1 receptor antagonist.Formula:C25H23F6N5O2Purity:98%Color and Shape:SolidMolecular weight:539.47MDMB-FUBICA
CAS:MDMB-FUBICA is a potent agonist of the cannabinoid receptors and exhibits psychoactive properties. It can be utilized in e-cigarettes.Formula:C23H25FN2O3Color and Shape:SolidMolecular weight:396.455AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formula:C25H33NO3Color and Shape:SolidMolecular weight:395.53SphK2-IN-2
SphK2-IN-2 (21g) is a potent and selective inhibitor of SphK2 (IC50: 0.23 μM).Formula:C21H25ClN10OColor and Shape:SolidMolecular weight:468.94CP-608039
CAS:CP-608039 is a selective adenosine A3 receptor agonist for both human A3 and human A1 receptors.Formula:C23H25ClN8O5Color and Shape:SolidMolecular weight:528.95Alixorexton
CAS:Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.Formula:C21H30N2O5SColor and Shape:SolidMolecular weight:422.538(S)-Butaprost free acid
CAS:(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].Formula:C23H38O5Color and Shape:SolidMolecular weight:394.54PSB-KK1415
CAS:PSB-KK1415 is a selective agonist for the human orphan G protein-coupled receptor GPR18, with an EC50 of 19.1 nM.Formula:C24H23ClN6O2Molecular weight:462.93HU-308
CAS:HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.
Formula:C27H42O3Color and Shape:SolidMolecular weight:414.62Histamine H3 antagonist-1
CAS:Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].
Formula:C24H28F3N3O2Color and Shape:SolidMolecular weight:447.49Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:Formula:C27H29N5OColor and Shape:SolidMolecular weight:439.55Osanetant HCl
CAS:Osanetant HCl is the (R)-enantiomer; neurokinin-3 receptor antagonistFormula:C35H42Cl3N3O2Color and Shape:SolidMolecular weight:643.09U91356
CAS:U91356 is an agonist of the dopamine receptors.Formula:C13H17N3OPurity:98%Color and Shape:SolidMolecular weight:231.29
