GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,030 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(196 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(58 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5982 products of "GPCR/G-Protein"
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SRA880 free base
CAS:SRA880: sst1-receptor antagonist, low affinity for other somatostatin receptors, binds to dopamine D4, may enhance antidepressant effects.Formula:C26H32N4O4Color and Shape:SolidMolecular weight:464.565-MeO-MET
CAS:5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32L803
CAS:L803 is a selective somatostatin receptor type 4 (SST4) agonist that can inhibit L-type calcium channel currents (ICa). It holds potential for research into degenerative diseases of retinal ganglion cells (RGC), such as glaucoma.Formula:C50H80N13O19PColor and Shape:SolidMolecular weight:1198.22Amylin (8-37) (human)
CAS:Amylin (8-37) (human) is a fragment of human IAPP with a hairpin structure.Formula:C138H215N41O46Color and Shape:SolidMolecular weight:3184.439-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
CAS:Meteneprost is a strong, long-lasting Prostaglandin E2 analog effective in ending early monkey pregnancies without causing fever or GI issues.Formula:C23H38O4Color and Shape:SolidMolecular weight:378.55325N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Color and Shape:SolidMolecular weight:382.84APP-FUBINACA
CAS:APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.Formula:C24H21FN4O2Color and Shape:SolidMolecular weight:416.45AM-0466
CAS:AM-0466 has a wide range of applications in life science related research.Formula:C27H19F3N4O4SColor and Shape:SolidMolecular weight:552.52ALD1910
ALD1910 is a humanized monoclonal antibody targeting PACAP38 and PACAP27. It inhibits PACAP signaling through pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a non-linear epitope within PACAP and prevents its binding to cell surfaces. It is useful for studying PACAP-mediated migraines.Color and Shape:Odour LiquidPF-4363467
CAS:PF-4363467 is a dopamine D3/D2 receptor antagonist that reduces opioid-seeking behavior without the side effects associated with D2 receptors. It has a Ki value of 3.1 nM for D3R and 692 nM for D2R.Formula:C22H30N2O3SColor and Shape:SolidMolecular weight:402.55BAY-6672
CAS:BAY-6672 is, a selective,oral, highly potent human prostaglandin F (FP) receptor antagonist, exerts antifibrotic effects by inhibiting PGF₂α activity.Formula:C26H27BrClN3O3Purity:99.51%Color and Shape:SolidMolecular weight:544.87PAF C-18
CAS:PAF C-18 is a natural phospholipid molecule belonging to the platelet-activating factor (PAF) family,, involved in hemostasis and thrombosis by binding to PAFR.Formula:C28H58NO7PPurity:>99.99%Color and Shape:SolidMolecular weight:551.74AD353
AD353 is a selective sigma-1 receptor ligand. It demonstrates high efficacy in models of capsaicin-induced allodynia and PGE2-induced mechanical hyperalgesia. Additionally, AD353 exhibits favorable pharmacokinetic properties.Formula:C23H30N2O2Color and Shape:SolidMolecular weight:366.517-TFM-PGF1α
CAS:17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.Formula:C24H35F3O5Color and Shape:SolidMolecular weight:460.53HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65Calcitonin Gene Related Peptide (CGRP) II, rat
CAS:CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.Formula:C163H267N51O50S2Purity:98%Color and Shape:SolidMolecular weight:3805.31Beraprost
CAS:Beraprost is a stable prostacyclin analog.Formula:C24H30O5Color and Shape:SolidMolecular weight:398.49Prepro VIP (81-122), human
CAS:Prepro VIP (81-122), human is a prepro-vasoactive intestinal polypeptide (VIP) derived peptide, corresponding to residues 81-122.Formula:C202H325N53O64SPurity:98%Color and Shape:SolidMolecular weight:4552.13Atilmotin
CAS:Atilmotin is a gastrointestinal agent for treating motility disorders.Formula:C86H135N20O19Color and Shape:SolidMolecular weight:1753.1463-hydroxy Desloratidine
CAS:3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.Formula:C19H19ClN2OColor and Shape:SolidMolecular weight:326.82
