GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5838 products of "GPCR/G-Protein"

Purity (%)

100

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ABT-702
CAS:
- 214697-26-4
ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.
Formula:C₂₂H₁₉BrN₆O
Purity:99.57%
Color and Shape:Soild
Molecular weight:463.33
Ref: TM-T4668L
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AMTG-DA1
AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.
Formula:C₁₀₁H₁₄₉IN₂₂O₂₅
Color and Shape:Solid
Molecular weight:2197.0109
Ref: TM-T207222
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GR 64349
CAS:
- 137593-52-3
Potent NK2 agonist, EC50=3.7 nM in rat colon; >1000x selectivity over NK1, >300x over NK3; effective in vivo.
Formula:C₄₂H₆₈N₁₀O₁₁S
Purity:98%
Color and Shape:Solid
Molecular weight:921.12
Ref: TM-TP2023
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ELA-21 (human)
CAS:
- 2245073-05-4
Apelin receptor agonist with high affinity for normal/PAH hearts (pKi 9.31/9.46). Blocks cAMP, promotes β-arrestin in vitro. Part of ELA-32.
Formula:C₁₁₂H₁₈₄N₄₀O₂₅S₃
Purity:98%
Color and Shape:Solid
Molecular weight:2587.12
Ref: TM-TP2096
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Nemifitide diTFA
CAS:
- 204992-09-6
Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.
Formula:C₃₇H₄₅F₇N₁₀O₁₀
Purity:99.78% - 99.84%
Color and Shape:Solid
Molecular weight:922.8
Ref: TM-TP1127
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Lintitript
CAS:
- 136381-85-6
Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.
Formula:C₂₀H₁₄ClN₃O₃S
Purity:99.28%
Color and Shape:Solid
Molecular weight:411.86
Ref: TM-T15759
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FSLLRY-NH2
CAS:
- 245329-02-6
PAR2 antagonist; counters taxol effects, PKC in mice; inhibits ERK, collagen in fibroblasts; lessens dermatophyte itch in mice.
Formula:C₃₉H₆₀N₁₀O₈
Purity:98%
Color and Shape:Solid
Molecular weight:796.97
Ref: TM-TP1904
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Haloperidol D4
CAS:
- 1189986-59-1
Haloperidol D4 is deuterium-labeled haloperidol.
Formula:C₂₁H₂₃ClFNO₂
Purity:98%
Color and Shape:Solid
Molecular weight:379.89
Ref: TM-T11535
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ELA-11(human)
CAS:
- 1784687-32-6
Apelin receptor agonist with high affinity (Ki = 14 nM). Blocks cAMP production and promotes β-arrestin activation; derived from ELA-32.
Formula:C₅₈H₉₀N₁₆O₁₃S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1283.57
Ref: TM-TP1922
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4-P-PDOT
CAS:
- 134865-74-0
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
Formula:C₁₉H₂₁NO
Purity:99.91%
Color and Shape:Solid
Molecular weight:279.38
Ref: TM-T14042
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PG106
CAS:
- 944111-22-2
Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.
Formula:C₅₁H₆₉N₁₃O₉
Purity:98%
Color and Shape:Solid
Molecular weight:1008.19
Ref: TM-TP1952
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Hydroxybupropion
CAS:
- 92264-81-8
Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).
Formula:C₁₃H₁₈ClNO₂
Purity:99.73%
Color and Shape:Off-White Solid
Molecular weight:255.74
Ref: TM-T11588
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Spantide acetate
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
Formula:C₇₇H₁₁₂N₂₀O₁₅
Purity:98.9200%
Color and Shape:Solid
Molecular weight:1557.84
Ref: TM-T20413L
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Crustacean Cardioactive Peptide (CCAP)
CAS:
- 309247-84-5
Crustacean Cardioactive Peptide (CCAP) is a conserved modified cyclic nonapeptide primary structure of PFCNAFTGC-NH2, a disulfide bridge between Cys3 and Cys9.
Formula:C₄₂H₅₈N₁₀O₁₂S₂
Purity:95.40%
Color and Shape:Solid
Molecular weight:959.1
Ref: TM-TP1413
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11-deoxy Prostaglandin E1
CAS:
- 37786-00-8
11-deoxy Prostaglandin E1 is a prostaglandin E1 analogue that has bronchodilator activity and can inhibit histamine-induced bronchoconstriction and cause
Formula:C₂₀H₃₄O₄
Color and Shape:Solid
Molecular weight:338.48
Ref: TM-T36770
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Xanthine amine congener trihydrochloride
CAS:
- 2459963-12-1
Xanthine amine congener trihydrochloride: potent adenosine antagonist, reverses effects of N6-cyclohexyladenosine on urine, sodium excretion, heart rate.
Formula:C₂₁H₂₉ClN₆O₄
Purity:98.81%
Color and Shape:Solid
Molecular weight:464.95
Ref: TM-T23535L
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Pal-Glu(OSu)-OH
CAS:
- 294855-91-7
Pal-Glu(OSu)-OH is a Liraglutide side chain, a GLP-1 agonist for type 2 diabetes study.
Formula:C₂₅H₄₂N₂O₇
Color and Shape:Solid
Molecular weight:482.618
Ref: TM-T40374
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Apelin-17(human, bovine)
CAS:
- 217082-57-0
Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).
Formula:C₉₆H₁₅₆N₃₄O₂₀S
Purity:98%
Color and Shape:Solid
Molecular weight:2138.56
Ref: TM-TP2092
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Sarafotoxin S6a
CAS:
- 126738-34-9
Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
Formula:C₁₀₅H₁₅₆N₂₈O₃₄S₅
Purity:98%
Color and Shape:Solid
Molecular weight:2514.85
Ref: TM-TP2119
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Secretin (28-54), human
CAS:
- 108153-74-8
Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.
Formula:C₁₃₀H₂₂₀N₄₄O₄₀
Purity:98%
Color and Shape:Powder
Molecular weight:3039.46
Ref: TM-TP1136