
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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MD01-67
CAS:MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.Formula:C37H58N8O8Color and Shape:SolidMolecular weight:742.91Plecanatide acetate
CAS:Plecanatide acetate: GC-C receptor agonist, EC50=190 nM (T84 cells), anti-inflammatory in murine colitis.Formula:C67H108N18O28S4Purity:98%Color and Shape:SolidMolecular weight:1741.94Dipentylone hydrochloride
CAS:Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formula:C14H20ClNO3Purity:99.94%Color and Shape:SolidMolecular weight:285.77MM 07
CAS:Biased agonist for apelin/G protein pathway, enhances eNOS and cell growth, reduces apoptosis, improves heart function, and dilates vessels.Formula:C67H106N22O14S3Purity:98%Color and Shape:SolidMolecular weight:1539.9[Ala17]-MCH acetate
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled).Formula:C99H159N29O28S4Purity:98.92%Color and Shape:SolidMolecular weight:2331.76Lanepitant
CAS:Lanepitant (LY303870) is a non-peptide neurokinin-1 (NK-1) antagonist with analgesic activity for the prevention of migraine.Formula:C33H45N5O3Purity:97.71%Color and Shape:SolidMolecular weight:559.74Spantide I
CAS:Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist.Formula:C75H108N20O13Purity:98%Color and Shape:SolidMolecular weight:1497.79MrgprX2 antagonist-4
CAS:MrgprX2 antagonist-4, from patent US20210128561A1, inhibits MrgprX2 receptor; useful for skin inflammation studies.Formula:C16H19N3OColor and Shape:SolidMolecular weight:269.348SB656104
CAS:SB656104 is a bioactive chemical.Formula:C25H30ClN3O3SColor and Shape:SolidMolecular weight:488.04Heterobivalent ligand-1
Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.Formula:C86H115FN16O21Color and Shape:SolidMolecular weight:1727.93Samelisant
CAS:Samelisant (SUVN-G3031), a selective H3 inverse agonist, Ki=8.7/9.8 nM in humans/rats, has anti-narcoleptic properties.Formula:C21H31N3O3Purity:99.59%Color and Shape:SolidMolecular weight:373.49Ref: TM-T9770
1mg105.00€2mg158.00€5mg260.00€1mL*10mM (DMSO)268.00€10mg416.00€25mg687.00€50mg964.00€100mg1,288.00€500mg2,602.00€(Hyp³)-Bradykinin acetate
(Hyp³)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts.Formula:C52H77N15O14Purity:99.46%Color and Shape:SolidMolecular weight:1136.26G-Protein antagonist peptide acetate
G-Protein antagonist peptide acetate is a truncated substance P-related peptide, competes with receptor for G protein binding.Formula:C59H68N12O11SPurity:98.06%Color and Shape:SolidMolecular weight:1153.33A3AR modulator 1
MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.Formula:C23H25IN4Color and Shape:SolidMolecular weight:484.38IRL-1038
CAS:ETB endothelin receptor antagonistFormula:C68H92N14O15S2Purity:98%Color and Shape:SolidMolecular weight:1409.67Lobeline sulfate
CAS:Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.Formula:C22H29NO6SPurity:98%Color and Shape:White PowderMolecular weight:435.54Ontazolast
CAS:Ontazolast: a small-molecule LTB4R antagonist targeting asthma and immune disorders.Formula:C21H25N3OPurity:99.94%Color and Shape:SoildMolecular weight:335.44Imipramine N-oxide
CAS:Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.Formula:C19H24N2OPurity:99.80%Color and Shape:SolidMolecular weight:296.41Ref: TM-T74205
1mg72.00€5mg157.00€1mL*10mM (DMSO)167.00€10mg241.00€25mg409.00€50mg565.00€100mg794.00€AC-264613
CAS:AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5.Formula:C19H18BrN3O2Purity:98%Color and Shape:SolidMolecular weight:400.28MLS1082
CAS:MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.Formula:C24H23N3O2Purity:99.53%Color and Shape:SolidMolecular weight:385.46

