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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 6011 products of "GPCR/G-Protein"

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  • MD01-67

    CAS:
    MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.
    Formula:C37H58N8O8
    Color and Shape:Solid
    Molecular weight:742.91

    Ref: TM-TP2936

    10mg
    To inquire
    50mg
    To inquire
  • Plecanatide acetate

    CAS:
    Plecanatide acetate: GC-C receptor agonist, EC50=190 nM (T84 cells), anti-inflammatory in murine colitis.
    Formula:C67H108N18O28S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1741.94

    Ref: TM-T12501

    1mg
    200.00€
    5mg
    780.00€
    10mg
    1,251.00€
    25mg
    2,583.00€
  • Dipentylone hydrochloride

    CAS:
    Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.
    Formula:C14H20ClNO3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:285.77

    Ref: TM-T205977

    1mg
    175.00€
    5mg
    434.00€
    10mg
    622.00€
    25mg
    973.00€
    50mg
    1,341.00€
    100mg
    1,765.00€
  • MM 07

    CAS:
    Biased agonist for apelin/G protein pathway, enhances eNOS and cell growth, reduces apoptosis, improves heart function, and dilates vessels.
    Formula:C67H106N22O14S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1539.9

    Ref: TM-TP2000

    1mg
    140.00€
  • [Ala17]-MCH acetate


    [Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled).
    Formula:C99H159N29O28S4
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:2331.76

    Ref: TM-TP1997L

    1mg
    110.00€
    5mg
    264.00€
    10mg
    385.00€
    25mg
    587.00€
    50mg
    800.00€
    100mg
    1,063.00€
    200mg
    1,423.00€
  • Lanepitant

    CAS:
    Lanepitant (LY303870) is a non-peptide neurokinin-1 (NK-1) antagonist with analgesic activity for the prevention of migraine.
    Formula:C33H45N5O3
    Purity:97.71%
    Color and Shape:Solid
    Molecular weight:559.74

    Ref: TM-T25615

    1mg
    175.00€
    5mg
    434.00€
    50mg
    1,341.00€
  • Spantide I

    CAS:
    Spantide antagonizes both bombesin & substance P. It is also tachykinin receptor antagonist.
    Formula:C75H108N20O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1497.79

    Ref: TM-T20413

    25mg
    778.00€
  • MrgprX2 antagonist-4

    CAS:
    MrgprX2 antagonist-4, from patent US20210128561A1, inhibits MrgprX2 receptor; useful for skin inflammation studies.
    Formula:C16H19N3O
    Color and Shape:Solid
    Molecular weight:269.348

    Ref: TM-T40268

    5mg
    873.00€
  • SB656104

    CAS:
    SB656104 is a bioactive chemical.
    Formula:C25H30ClN3O3S
    Color and Shape:Solid
    Molecular weight:488.04

    Ref: TM-T34546

    25mg
    To inquire
    50mg
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    100mg
    To inquire
  • Heterobivalent ligand-1


    Heterobivalent ligand-1 targets A2A-D2 receptor heteromer with affinity: Kd for A2A=2.1 nM, D2=0.13 nM.
    Formula:C86H115FN16O21
    Color and Shape:Solid
    Molecular weight:1727.93

    Ref: TM-T74399

    5mg
    To inquire
    50mg
    To inquire
  • Samelisant

    CAS:
    Samelisant (SUVN-G3031), a selective H3 inverse agonist, Ki=8.7/9.8 nM in humans/rats, has anti-narcoleptic properties.
    Formula:C21H31N3O3
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:373.49

    Ref: TM-T9770

    1mg
    105.00€
    2mg
    158.00€
    5mg
    260.00€
    1mL*10mM (DMSO)
    268.00€
    10mg
    416.00€
    25mg
    687.00€
    50mg
    964.00€
    100mg
    1,288.00€
    500mg
    2,602.00€
  • (Hyp³)-Bradykinin acetate


    (Hyp³)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts.
    Formula:C52H77N15O14
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:1136.26

    Ref: TM-T36442L

    1mg
    49.00€
    5mg
    92.00€
    10mg
    142.00€
    25mg
    250.00€
    50mg
    366.00€
    100mg
    522.00€
  • G-Protein antagonist peptide acetate


    G-Protein antagonist peptide acetate is a truncated substance P-related peptide, competes with receptor for G protein binding.
    Formula:C59H68N12O11S
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:1153.33

    Ref: TM-TP1902L1

    1mg
    137.00€
    2mg
    221.00€
    5mg
    346.00€
    10mg
    552.00€
    25mg
    873.00€
    50mg
    1,188.00€
    100mg
    1,605.00€
  • A3AR modulator 1


    MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.
    Formula:C23H25IN4
    Color and Shape:Solid
    Molecular weight:484.38

    Ref: TM-T74993

    5mg
    To inquire
    50mg
    To inquire
  • IRL-1038

    CAS:
    ETB endothelin receptor antagonist
    Formula:C68H92N14O15S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1409.67

    Ref: TM-TP2262

    1mg
    To inquire
    100mg
    To inquire
    500mg
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  • Lobeline sulfate

    CAS:
    Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.
    Formula:C22H29NO6S
    Purity:98%
    Color and Shape:White Powder
    Molecular weight:435.54

    Ref: TM-T22357

    25mg
    1,369.00€
  • Ontazolast

    CAS:
    Ontazolast: a small-molecule LTB4R antagonist targeting asthma and immune disorders.
    Formula:C21H25N3O
    Purity:99.94%
    Color and Shape:Soild
    Molecular weight:335.44

    Ref: TM-T68119

    1mg
    56.00€
    5mg
    124.00€
    10mg
    177.00€
    25mg
    334.00€
    50mg
    444.00€
  • Imipramine N-oxide

    CAS:
    Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.
    Formula:C19H24N2O
    Purity:99.80%
    Color and Shape:Solid
    Molecular weight:296.41

    Ref: TM-T74205

    1mg
    72.00€
    5mg
    157.00€
    1mL*10mM (DMSO)
    167.00€
    10mg
    241.00€
    25mg
    409.00€
    50mg
    565.00€
    100mg
    794.00€
  • AC-264613

    CAS:
    AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5.
    Formula:C19H18BrN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.28

    Ref: TM-T4186

    1mg
    124.00€
    5mg
    379.00€
    10mg
    695.00€
    25mg
    1,575.00€
  • MLS1082

    CAS:
    MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.
    Formula:C24H23N3O2
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:385.46

    Ref: TM-T41014

    1mg
    72.00€
    5mg
    157.00€
    10mg
    241.00€
    25mg
    484.00€
    50mg
    762.00€
    100mg
    1,228.00€
    200mg
    1,607.00€