
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,003 products)
- Adenosine Receptor(247 products)
- Adrenergic Receptor(3,010 products)
- Bombesin Receptor(33 products)
- Bradykinin Receptor(60 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(215 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(435 products)
- Endothelin Receptor(83 products)
- GNRH Receptor(82 products)
- GPCR19(33 products)
- GRK(32 products)
- GTPase(22 products)
- Glucagon Receptor(190 products)
- Hedgehog/Smoothened(48 products)
- Histamine Receptor(381 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(321 products)
- PAFR(13 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5838 products of "GPCR/G-Protein"
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Tilisolol HCl
CAS:Tilisolol, a nonselective beta-blocker, dilates dog coronary arteries via ATP-sensitive K(+) channels.Formula:C17H25ClN2O3Purity:98%Color and Shape:SolidMolecular weight:340.85LY 344864 S-enantiomer
CAS:LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42Bopindolol fumarate
CAS:<p>Bopindolol fumarate: non-selective β1/β2-adrenoceptor blocker, partial agonist, low β3 affinity, treats hypertension.</p>Formula:C27H32N2O7Color and Shape:SolidMolecular weight:496.56VNA-932
CAS:<p>VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).</p>Formula:C23H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:402.88I-SAP
CAS:<p>I-SAP: TP receptor blocker, alters platelet shape without causing clumping, EC50 9.7 nM, max binding pH 6.5-7.4, Kd 468-490 pM.</p>Formula:C22H30INO4SColor and Shape:SolidMolecular weight:531.45PD-89211
CAS:PD 89211 selectively blocks dopamine D4.2 receptor >800x vs. other subtypes; reverses quinpirole effect in vitro (IC50 = 2.1 nM).Formula:C19H21ClN4OPurity:98%Color and Shape:SolidMolecular weight:356.85MK-0249
CAS:<p>MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).</p>Formula:C23H24F3N3O2Purity:99.90%Color and Shape:SolidMolecular weight:431.455-HT6/5-HT2A receptor ligand-1
CAS:<p>Compound 33 is a dual 5-HT6/5-HT2A antagonist with Ki values of 2 nM and 11 nM, respectively, useful in neuro/psychiatric research.</p>Formula:C21H19FN2O2Color and Shape:SolidMolecular weight:350.39H3 receptor-MO-1
CAS:H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.Formula:C20H27N3O2Purity:99.11%Color and Shape:SolidMolecular weight:341.45Rocastine
CAS:<p>Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.</p>Formula:C13H19N3OSPurity:98.26%Color and Shape:SolidMolecular weight:265.37QF0301B
CAS:QF0301B is a potent α1-adrenergic receptor antagonist with inhibitory effects on α2-adrenergic receptors, 5-HT2A and histamine H1 receptors.Formula:C23H28N2O2Purity:>99.99%Color and Shape:SolidMolecular weight:364.48Tulopafant
CAS:Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.Formula:C25H19N3O2SPurity:99.38%Color and Shape:SolidMolecular weight:425.5CL-216303 HCl
CAS:CL-216303 HCl, a dopamine transporter inhibitor and a 5-HT inhibitor, is used potentially for the treatment of depression.Formula:C11H12Cl3NPurity:98%Color and Shape:SolidMolecular weight:264.58Oxiperomide
CAS:Oxiperomide is a dopamine D2 and muscarinic M1 receptor ligand. It also has putative antipsychotic and pro-cognitive potential.Formula:C20H23N3O2Purity:98%Color and Shape:SolidMolecular weight:337.42T-0509
CAS:<p>T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-</p>Formula:C18H23NO5Purity:97.52% - 98.43%Color and Shape:SolidMolecular weight:333.38Glucagon receptor antagonists-2
CAS:Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.Formula:C22H30FNO2Purity:98%Color and Shape:SolidMolecular weight:359.48JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFormula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.74Alimemazine
CAS:Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.Formula:C18H22N2SPurity:98%Color and Shape:Crystals SolidMolecular weight:298.45NGB 2904 hydrochloride
CAS:dopamine D3 receptor antagonistFormula:C28H30Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:530.92Isoproterenol-d7 HCl
CAS:Isoproterenol-d7: internal standard for GC/LC-MS. β1-/β2-AR agonist, not for β3. Lowers blood pressure, tackles bradydysrhythmias, asthma.Formula:C11H18ClNO3Molecular weight:254.76Aminopotentidine
CAS:H2 antagonistFormula:C26H35N7O2Purity:98%Color and Shape:SolidMolecular weight:477.6TC-C 14G
CAS:CB1 receptor inverse agonistFormula:C24H17Cl2F2NO4Purity:98%Color and Shape:SolidMolecular weight:492.3RS 64459-193
CAS:RS 64459-193 has a high affinity for the 5-HT1A binding site.Formula:C26H36Cl2N2O2Color and Shape:SolidMolecular weight:479.48CCK-A receptor inhibitor 1
CAS:<p>CCK-A receptor inhibitor 1 is a potent inhibitor of the cholecystokinin A (CCK-A) receptor (IC50: 340 nM).CCK-A receptor inhibitor 1 can be used for the study</p>Formula:C25H35NO6SPurity:99.47%Color and Shape:SolidMolecular weight:477.61Pamatolol
CAS:Pamatolol is a selective and potent beta-adrenoceptor antagonist that has not shown sympathomimetic activity in ex vivo experiments.Formula:C16H26N2O4Purity:>99.99%Color and Shape:SolidMolecular weight:310.39Cicloprolol hydrochloride
CAS:Cicloprolol hydrochloride is a new potent and selective beta 1-adrenoceptor antagonist with partial agonist activity for the study of coronary heart disease.Formula:C18H30ClNO4Purity:97.26%Color and Shape:SolidMolecular weight:359.89Bamirastine
CAS:Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 value of 17.3 nM.Bamirastine has an inhibitory effect onFormula:C31H37N5O3Purity:96.68%Color and Shape:SolidMolecular weight:527.66LEI-101
CAS:LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.Formula:C23H25FN4O4SPurity:98%Color and Shape:SolidMolecular weight:472.53(4E)-SUN9221
CAS:(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity inFormula:C25H31FN4O3Purity:97.79%Color and Shape:SolidMolecular weight:454.54L-771688
CAS:L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benignFormula:C28H33F2N5O5Purity:94.15%Color and Shape:SolidMolecular weight:557.59GSK-894490A
CAS:GSK-894490A is an agonist of ghrelin receptor. GSK-894490A crosses the blood/brain barrier and elicit pro-cognitive effects.Formula:C24H30ClN3O4SColor and Shape:SolidMolecular weight:492.03Zolantidine dimaleate
CAS:H2 receptor antagonistFormula:C26H31N3O5SPurity:98%Color and Shape:SolidMolecular weight:497.61ONO4057
CAS:ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM.Formula:C27H34O7Purity:>99.99%Color and Shape:SolidMolecular weight:470.55PAF-AN-1
CAS:<p>PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death.</p>Formula:C28H28N2O3Purity:98.06%Color and Shape:SolidMolecular weight:440.53L-803087
CAS:L-803087: potent sst4 receptor agonist, 0.7 nM Ki, 280x selectivity, boosts AMPA responses & seizures in mice.Formula:C25H29F2N5O3Purity:99.37%Color and Shape:SolidMolecular weight:485.53CP-66948
CAS:CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.Formula:C13H20N6SPurity:99.14%Color and Shape:SolidMolecular weight:292.4Indanidine
CAS:Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in theFormula:C11H13N5Purity:>99.99%Color and Shape:SolidMolecular weight:215.25RS-601
CAS:RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in aFormula:C22H23F6NO4SPurity:99.31%Color and Shape:SolidMolecular weight:511.48TD-5471 hydrochloride
CAS:TD-5471 hydrochloride is a selective and potent long-acting human β2-adrenergic receptor agonist for the treatment of chronic obstructive pulmonary disease (Formula:C32H32ClN3O4Purity:99.57%Color and Shape:SolidMolecular weight:558.07Masupirdine mesylate
CAS:Masupirdine mesylate (SUVN-502 mesylate) is a 5-HT6 receptor antagonist.Masupirdine mesylate is used to study neurological disorders such as Alzheimer's diseaseFormula:C23H32BrN3O9S3Purity:99.57%Color and Shape:SolidMolecular weight:670.61Odapipam
CAS:Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).Formula:C19H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:329.82SLM6031434 HCl
CAS:SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.Formula:C22H31ClF3N5O2Purity:98%Color and Shape:SolidMolecular weight:489.96p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H29Cl2FN4O2Purity:99.55%Color and Shape:SolidMolecular weight:507.43ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Formula:C22H22N2OPurity:99.94%Color and Shape:SolidMolecular weight:330.42PF-03654764
CAS:<p>PF-03654764, an oral H3 receptor blocker, Ki: human 1.2 nM, rat 7.9 nM, used with Fexofenadine for allergic rhinitis.</p>Formula:C20H28F2N2OPurity:>99.99%Color and Shape:SolidMolecular weight:350.45Napitane
CAS:<p>napitane (A 75200) is a novel catecholamine uptake inhibitor with inhibitory effects on α-adrenergic receptors and potential antidepressant activity for the</p>Formula:C22H25NO2Purity:99.77% - 99.89%Color and Shape:SolidMolecular weight:335.44Methdilazine Hydrochloride
CAS:Methdilazine Hydrochloride (Bristaline) is a histamine H1 receptor antagonist for dermatologic conditions and relief of itching by allergies or rhinitis.Formula:C18H21ClN2SColor and Shape:Light-Tan Crystalline Powder 4 8-6 (Ntp 1992)Molecular weight:332.89GB83
CAS:GB83 is a selective human protease activated receptor 2 (PAR2) antagonist.Formula:C32H44N4O4Purity:98%Color and Shape:SolidMolecular weight:548.72WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurity:98%Color and Shape:SolidMolecular weight:519.52Norfenefrine HCl
CAS:<p>Norfenefrine HCl is an α1-adrenergic receptor agonist, an endogenous neurotransmitter and sympathomimetic drug for hypotension,glycerol adipose.</p>Formula:C8H12ClNO2Purity:99.44%Color and Shape:SolidMolecular weight:189.64Arvanil
CAS:Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.Formula:C28H41NO3Purity:99.49%Color and Shape:SolidMolecular weight:439.63PGN-9856
CAS:PGN-9856 is an EP2 receptor ligand and EP2 receptor agonist with anti-inflammatory and intraocular pressure-lowering properties, useful for glaucoma research.Formula:C21H15F2NO4Purity:99.27%Color and Shape:SolidMolecular weight:383.35CCK-B Receptor Antagonist 1
CAS:CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor agonist and has the potential of reducing the secretion of gastric acid.Formula:C28H30N6O3Purity:98%Color and Shape:SolidMolecular weight:498.58Propiomazine HCl
CAS:Propiomazine HCl is an analgesia adjunct.Formula:C20H25ClN2OSColor and Shape:SolidMolecular weight:376.94RP73870
CAS:RP73870 is a gastrin/cholecystokinin-B receptor antagonist and H2 receptor antagonist with potent anti-ulcer activity.Formula:C27H30N4O7SPurity:98%Color and Shape:SolidMolecular weight:554.61Trimopam
CAS:Trimopam is a dopamine receptor agonist of the benzazepine group.Formula:C19H23NO2Color and Shape:SolidMolecular weight:297.39Daledalin tosylate
CAS:Daledalin tosylate is an antidepressant.Formula:C26H32N2O3SColor and Shape:SolidMolecular weight:452.61PD 118717
CAS:PD 118717: a piperazinyl benzopyranone dopamine agonist with potential antipsychotic properties and no neurological side effects in tests.Formula:C20H22N4O3Purity:98%Color and Shape:SolidMolecular weight:366.41Bucumarol (HCl)
CAS:Bucumarol is a beta-adrenergic blocking agent.Formula:C17H24ClNO4Color and Shape:SolidMolecular weight:341.83MHP 133
CAS:<p>MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).</p>Formula:C17H20ClN5O3Purity:98%Color and Shape:SolidMolecular weight:377.83SKF-80723 HBr
CAS:SKF-80723 HBr is a potent D1 agonist enhancing quinpirole-induced circling in 6-OHDA lesioned rats.Formula:C16H16BrNO2Purity:98%Color and Shape:SolidMolecular weight:334.21Trebenzomine
CAS:Trebenzomine is apsychotropic agent with potential as an antidepressant and an antipsychotic.Formula:C12H17NOPurity:98%Color and Shape:SolidMolecular weight:191.27VK-II-86
CAS:VK-II-86 is a non-β-blocking carvedilol analog. It prevents ouabain-Induced cardiotoxicityFormula:C25H28N2O4Purity:98%Color and Shape:SolidMolecular weight:420.5LPA2 antagonist 1
CAS:LPA2 antagonist 1 is a potent LPA2 antagonist.Formula:C20H23Cl2N5O2S2Purity:99.85%Color and Shape:SolidMolecular weight:500.47(R)-Viloxazine Hydrochloride
CAS:(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine.Formula:C13H20ClNO3Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:273.76Ro 363
CAS:RO 363: Potent β1-adrenoceptor agonist, boosts heart contractility, lowers diastolic pressure.Formula:C19H25NO6Purity:98%Color and Shape:SolidMolecular weight:363.4A1AR antagonist 3
CAS:Compound 13: selective A1AR antagonist, Ki human A1: 9.69 nM, rat A1: 0.529 nM, useful for neurological research.Formula:C25H20N2O3SColor and Shape:SolidMolecular weight:428.5Argiprestocin
CAS:Argiprestocin: antidiuretic, regulates osmolality, neurohypophysial hormone, vasoconstrictor.Formula:C43H67N15O12S2Purity:99.34%Color and Shape:SolidMolecular weight:1050.22RWJ 52353
CAS:α2D adrenergic receptor agonistFormula:C11H10N2SPurity:98%Color and Shape:SolidMolecular weight:202.28AF40431
CAS:AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin.Formula:C17H21NO5Color and Shape:SolidMolecular weight:319.35VL-0395
CAS:VL-0395 is an antagonist of CCK1 receptor.Formula:C25H21N3O4Purity:98%Color and Shape:SolidMolecular weight:427.45Iloperidone hydrochloride
CAS:Iloperidone hydrochloride is a D(2)/5-HT(2) receptor antagonist. It is also an atypical antipsychotic for the treatment of schizophrenia symptoms.Formula:C24H28ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:462.95A1AR antagonist 5
CAS:<p>A1AR antagonist 5 (compound 20) is a potent and selective antagonist of A1 adenosine receptor (A1AR) with a pKi of 6.11 and a pIC 50 of 5.83 [1].</p>Formula:C17H15ClN4OColor and Shape:SolidMolecular weight:326.78SB-269970
CAS:SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49Mabuterol, (S)-
CAS:Mabuterol, a β2 adrenoreceptor agonist, lowers rat blood pressure and boosts guinea pig heart rate/force, not affecting other receptors.Formula:C13H18ClF3N2OColor and Shape:SolidMolecular weight:310.74MRS1097
CAS:MRS1097 is a selective antagonist A3 adenosine receptor.Formula:C26H27NO4Purity:98%Color and Shape:SolidMolecular weight:417.5CBK289001
CAS:<p>CBK289001 inhibits TRAP 5b MV, 5b OX & 5a OX with IC50s: 125μM, 4.21μM, 14.2μM.</p>Formula:C19H20N6O4Color and Shape:SolidMolecular weight:396.4SB 258719 hydrochloride
CAS:Selective 5-HT7 receptor antagonistFormula:C18H31ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:374.97Colterol HCl
CAS:Colterol HCl, a β2-adrenoceptor agonist salt, is used for bronchospasm in asthma and COPD.Formula:C12H20ClNO3Color and Shape:SolidMolecular weight:261.75Dacemazine
CAS:Dacemazine is used to treat depression.Formula:C16H16N2OSColor and Shape:SolidMolecular weight:284.38Fulimetibant
CAS:Fulimetibant is a bradykinin receptor antagonist.Formula:C25H21F4N3O3Color and Shape:SolidMolecular weight:487.45TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purity:98%Color and Shape:SolidMolecular weight:447.53Ambenoxan hydrochloride
CAS:Ambenoxan hydrochloride is a centrally acting skeletal muscle relaxant.Formula:C14H22ClNO4Color and Shape:SolidMolecular weight:303.78Ambucetamide
CAS:Ambucetamide is an antispasmodic, it may inhibit or diminish the spontaneous rhythmical activity of the human myometrium.Formula:C17H28N2O2Color and Shape:SolidMolecular weight:292.42BAY-386
CAS:BAY-386 is a PAR1 receptor inhibitor which suppresses activation of thrombin and platelet activity.Formula:C22H25F3N4O5SColor and Shape:SolidMolecular weight:514.52Ranitidine bismuth citrate
CAS:Ranitidine bismuth citrate, oral H2 blocker, IC50 3.3 µM, targets SARS-CoV-2 cells, treats H. pylori; MIC90 16 ng/L.Formula:C19H27BiN4O10SColor and Shape:SolidMolecular weight:712.48F-15599 tosylate
CAS:F-15599 tosylate is a selective 5-HT(1A) agonist.Formula:C26H29ClF2N4O4SColor and Shape:SolidMolecular weight:567.05VUF14738
CAS:VUF14738 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Formula:C25H32N4O2Color and Shape:SolidMolecular weight:420.55OPC-14523 free base
CAS:OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.Formula:C23H28ClN3O2Purity:98%Color and Shape:SolidMolecular weight:413.94LY320135
CAS:CB1 receptor antagonist/inverse agonistFormula:C24H17NO4Purity:98%Color and Shape:SolidMolecular weight:383.4Cyclazosin HCl
CAS:Cyclazosin HCl is an α-adrenergic receptor antagonist that can be used to study non-arteritic ischemic optic neuropathy.Formula:C23H28ClN5O4Purity:99.10%Color and Shape:SolidMolecular weight:473.95Albuterol adipate
CAS:Albuterol adipate, a β2-AR agonist salt, treats asthma/COPD, with high selectivity for pulmonary over cardiac receptors.Formula:C32H52N2O10Color and Shape:SolidMolecular weight:624.77Levomepromazine Maleate
CAS:Levomepromazine Maleate: TCA and SNRI with antihistamine, antiadrenergic, and anticholinergic properties.Formula:C23H28N2O5SColor and Shape:SolidMolecular weight:444.546ZD7114 free base
CAS:ZD7114 (ICI-D7114) selectively activates brown fat, boosts thermogenesis, and aids in obesity and metabolic disorders.Formula:C22H30N2O6Color and Shape:SolidMolecular weight:418.48L-694,247
CAS:L-694,247 is a 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.Formula:C20H21N5O3SPurity:98.36%Color and Shape:White SolidMolecular weight:411.48Aceprometazine
CAS:Aceprometazine (1664CB) is an antipsychotic which is orally active. Aceprometazine can be used in psychiatric disorders research, for example, depression [1].Formula:C19H22N2OSColor and Shape:SolidMolecular weight:326.46Ricinelaidic Acid
CAS:Ricinelaidic acid blocks LTB4 receptors; hampers human neutrophil responses; reduces rat bronchoconstriction by 46% at 1 mg/kg i.v.Formula:C18H34O3Color and Shape:SolidMolecular weight:298.46Darbufelone
CAS:<p>Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF2α and LTB4.</p>Formula:C18H24N2O2SPurity:99.72%Color and Shape:SolidMolecular weight:332.46GBR-12935 maleate
CAS:GBR-12935: dopamine reuptake inhibitor, used in research for Parkinson's and brain's dopamine pathways.Formula:C32H38N2O5Color and Shape:SolidMolecular weight:530.6656-Chloromelatonin
CAS:6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.Formula:C13H15ClN2O2Purity:97.26% - 99.25%Color and Shape:SolidMolecular weight:266.72(R)-Mequitazine
CAS:<p>(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.</p>Formula:C20H22N2SColor and Shape:SolidMolecular weight:322.47VRX 03011 Potassium salt
CAS:VRX 03011, a 5-HT4 partial agonist, is used potentially for the treatment of Alzheimer's disease.Formula:C19H27KN3O3SPurity:98%Color and Shape:SolidMolecular weight:416.6Quinpirole
CAS:Quinpirole is a dopamine D2/D3 receptor agonist.Formula:C13H21N3Color and Shape:SolidMolecular weight:219.33KUL-7211 racemate
CAS:KUL 7211, a selective β-adrenoceptor agonist, exists as a racemate, referred to as KUL 7211 racemate, which is the mixture of its enantiomers.Formula:C19H23NO5Purity:98%Color and Shape:SolidMolecular weight:345.39Thiothixene hydrochloride
CAS:Thiothixene hydrochloride is an antipsychotic agent that can be used in the study of schizophrenia and bipolar mania.Formula:C23H30ClN3O2S2Color and Shape:SolidMolecular weight:480.08Isoetharine hydrochloride
CAS:Isoetharine HCl, a selective, short-acting oral β-agonist, is used as a bronchodilator for inhalation therapy.Formula:C13H22ClNO3Color and Shape:SolidMolecular weight:275.77A-304121
CAS:A-304121 is a histamine H(3) receptor.Formula:C20H29N3O3Color and Shape:SolidMolecular weight:359.46Trimethaphan camsylate
CAS:Trimethaphan camsylate is a nicotinic antagonist that has been used as a ganglionic blocker in hypertension.Formula:C32H40N2O5S2Color and Shape:SolidMolecular weight:596.801Ro 23-3423
CAS:Ro 23-3423 is a specific inhibitor of thromboxane synthetase.Formula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45Glucagon receptor antagonists-5
CAS:Oral indazole-based glucagon antagonist, Ki: 32 nM, may treat type 2 diabetes.Formula:C30H29ClF3N3O3Purity:98%Color and Shape:SolidMolecular weight:572.02Proxodolol hydrochloride
CAS:Proxodolol, a β-adrenergic receptor antagonist, is used potentially for the treatment of glaucoma, hypertension and angina.Formula:C17H26ClN3O4Color and Shape:SolidMolecular weight:371.86Opaganib HCl
CAS:ABC294640 (Opaganib) is an SK2 inhibitor with potential anti-cancer effects; it blocks S1P production to induce apoptosis.Formula:C23H26Cl2N2OColor and Shape:SolidMolecular weight:417.37GSK466317A
CAS:GSK466317A is a GRK2 inhibitor.Formula:C21H16ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:448.83Dicentrine HCl
CAS:Dicentrine HCl is the salt form of Dicentrine, an alpha 1-adrenoceptor antagonist effective against human hyperplastic prostates.Formula:C20H22ClNO4Color and Shape:SolidMolecular weight:375.85Org-12962 hydrochloride
CAS:Org-12962 hydrochloride is a 5-HT2C receptor agonist.Formula:C10H12Cl2F3N3Purity:98%Color and Shape:SolidMolecular weight:302.12DH-97
CAS:DH-97 is a potent MT2 melatonin receptor antagonist (pKi value = 8.03).Formula:C22H26N2OColor and Shape:SolidMolecular weight:334.45Esreboxetine
CAS:Esreboxetine( PNU-165442, (S,S) -reboxetine) is a selective inhibitor of norepinephrine reuptake.Formula:C19H23NO3Color and Shape:SolidMolecular weight:313.39CGP 25454A
CAS:CGP 25454A is a novel and selective antagonist of the presynaptic dopamine autoreceptor.Formula:C15H21Cl2N3O2Color and Shape:SolidMolecular weight:346.25Bitolterol
CAS:Bitolterol is a new beta 2-adrenergic agonist and classified as a pro-drug.Formula:C28H31NO5Color and Shape:SolidMolecular weight:461.55R-SKF-38393A HCl
CAS:R(+)-SKF-38393A is a D1 dopamine receptor agonist and also is a more active enantiomer of (±)-SKF-38393A.Formula:C16H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:291.77A1AR antagonist 4
CAS:Compound 22: A1AR antagonist, pIC50 5.51, pKi 6.29, potent and selective.Formula:C23H25N3O2Color and Shape:SolidMolecular weight:375.465-Methylurapidil
CAS:<p>5-Methylurapidil is an alpha1A-adrenoceptor antagonist.</p>Formula:C21H31N5O3Purity:98%Color and Shape:SolidMolecular weight:401.55-HT4 antagonist 1
CAS:5-HT4 antagonist 1 is an antagonist of 5-HT4 (pKi = 9.6).Formula:C23H36N4O5SPurity:99.75%Color and Shape:SolidMolecular weight:480.62Glucagon Receptor Antagonist I
CAS:Glucagon antagonist I blocks the GCGR (IC50=181 nM), stops glucagon-induced glycogenolysis, and lowers glucose in glucagon-treated humanized mice.Formula:C20H30N2OSColor and Shape:SolidMolecular weight:346.53Sch 44643
CAS:Sch 44643 is an antagonist of platelet activating factor with oral activity.Formula:C25H22ClN3O2Color and Shape:SolidMolecular weight:431.91A2AR-agonist-1
CAS:<p>A2AR-agonist-1 targets A2A Receptor/ENT1 for neuroprotection; potent with Ki of 4.39 (A2AR), 3.47 (ENT1).</p>Formula:C20H22N6O4Purity:99.9%Color and Shape:SolidMolecular weight:410.43DR4485 hydrochloride
CAS:5-HT7 antagonistFormula:C26H29Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:491.88Iferanserin HCl
CAS:Iferanserin HCl is a selective serotonin receptor antagonist.Formula:C23H29ClN2OColor and Shape:SolidMolecular weight:384.95GYKI-13380
CAS:GYKI-13380, also known as LS-79445, is a small molecule with potent bioactivity. Detail information has not been published yet.Formula:C16H22N2O3Color and Shape:SolidMolecular weight:290.36Ksg 504
CAS:Ksg 504 has superior selectivity and affinity to CCK-A receptors and derived from proglumide.Formula:C31H49N5O8SColor and Shape:SolidMolecular weight:651.81VER-3323
CAS:VER-3323 is a selective agonist for the 5-HT2B and 5-HT2C serotonin receptor with potent anorectic effects in animal studies.Formula:C11H15BrN2Purity:98%Color and Shape:SolidMolecular weight:255.15Reproterol hydrochloride
CAS:Reproterol hydrochloride, a β2 adrenoreceptor agonist, is used to treat asthma and chronic obstructive pulmonary disease (COPD).Formula:C18H24ClN5O5Purity:98%Color and Shape:SolidMolecular weight:425.87XCC
CAS:XCC is an Adenosine receptor antagonist.Formula:C19H22N4O5Purity:98%Color and Shape:SolidMolecular weight:386.4U 101958
CAS:U 101958 is a putative antipsychotic agent It is also a highly selective dopamine D4 receptor antagonist.Formula:C20H27N3OColor and Shape:SolidMolecular weight:325.45ZCZ011
CAS:ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.Formula:C21H18N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.44Fonazine hydrochloride
CAS:Fonazine hydrochloride is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.Formula:C19H26ClN3O2S2Color and Shape:SolidMolecular weight:428.01S1P1 Agonist III
CAS:S1P1 Agonist III is an orally active S1P1 receptor agonist (EC₅₀ = 18 nM) with applications in inflammation, immunology, and receptor signaling studies.Formula:C21H16F3N3O3Purity:99.08%Color and Shape:SolidMolecular weight:415.37HEAT hydrochloride
CAS:HEAT hydrochloride is an α1-adrenoceptor antagonist.Formula:C19H22ClNO2Purity:98%Color and Shape:SolidMolecular weight:331.84Sch 40120
CAS:Sch 40120 is an inhibitor of 5-lipoxygenase.Formula:C18H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:310.78CAD031
CAS:<p>CAD031, a more active derivative of the Alzheimer's disease (AD) targeting agent J147, exhibits neuroprotective and memory-enhancing properties.</p>Formula:C18H14F6N2O2Color and Shape:SolidMolecular weight:404.31Denopamine
CAS:Denopamine is an agonist of 1-Adrenoceptor.Formula:C18H23NO4Color and Shape:SolidMolecular weight:317.38MRS2690
CAS:MRS2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.Formula:C15H24N2O16P2SColor and Shape:SolidMolecular weight:582.37SEP-363856
CAS:<p>SEP-363856, a non-D2/5-HT2A, orally active CNS psychotropic may treat schizophrenia.</p>Formula:C9H13NOSPurity:98%Color and Shape:SolidMolecular weight:183.275-trans-Prostaglandin E2
CAS:5-trans-PGE2 speeds up fibrinolysis, boosts tissue-PA mediated plasminogen activation, and blocks platelet clumping in human PRP.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.47Toreforant
CAS:Toreforant is an effective and selective histamine H4 receptor antagonist (Ki at the human receptor: 8.4 nM).Formula:C23H32N6Purity:98%Color and Shape:SolidMolecular weight:392.54TISCH
CAS:TISCH is a potent and selective iodinated ligand for CNS D1 dopamine receptor.Formula:C17H17ClINOColor and Shape:SolidMolecular weight:413.68JTC-017
CAS:JTC-017 is an antagonist of Corticotropin-releasing hormone receptor 1.Formula:C20H25Cl2N3O5SColor and Shape:SolidMolecular weight:490.4Fonazine mesylate
CAS:Fonazine mesylate is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.Formula:C20H29N3O5S3Color and Shape:SolidMolecular weight:487.65Flerobuterol HCl
CAS:"Flerobuterol, a β adrenergic agonist, may treat depression by boosting serotonin synthesis and Trp in the brain."Formula:C12H19ClFNOPurity:98%Color and Shape:SolidMolecular weight:247.74Zimelidine
CAS:Zimelidine, a withdrawn antidepressant, posed Guillain-Barre risk.Formula:C16H17BrN2Purity:98%Color and Shape:SolidMolecular weight:317.22RP-72540
CAS:RP-72540: CCKB receptor blocker, 200x more selective for CCKA, binds to stomach gastrin, limits [3H]pCCK-8 in mouse brain, <0.01% reaches forebrain.Formula:C28H30N4O6Purity:98%Color and Shape:SolidMolecular weight:518.56hBChE-IN-2
CAS:<p>hBChE-IN-2 is a BChE inhibitor and CB2R agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.</p>Formula:C27H36N4O3Purity:99.60% - 99.83%Color and Shape:SoildMolecular weight:464.6Usmarapride free base
CAS:Usmarapride free base (SUVN-D4010 free base) is a partial agonist of 5-HT4 receptors, used in Alzheimer's disease research.Formula:C21H29N5O2Purity:99.91% - 99.91%Color and Shape:SolidMolecular weight:383.49Sulfisoxazole diethanolamine
CAS:Sulfisoxazole diethanolamine: a sulfonamide antibacterial, endothelin receptors A and B antagonist, inhibits breast cancer exosomes.Formula:C15H24N4O5SColor and Shape:SolidMolecular weight:372.44A-971432
CAS:A-971432: selective S1P5 agonist, IC50 = 0.006 µM. Enhances blood-brain barrier, reduces Huntington’s symptoms in mice at 0.1 mg/kg.Formula:C18H17Cl2NO3Color and Shape:SolidMolecular weight:366.24Brl 22321
CAS:Brl 22321 is a mast cell stabilizer.Formula:C12H9N3O2Color and Shape:SolidMolecular weight:227.22Isoetharine
CAS:Isoetharine is a selective agonist of β2-adrenergic receptor used as a bronchodilator for emphysema, bronchitis, and asthma.Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.31Imnopitant
CAS:Imnopitant is an antagonist of the NK1 receptor [1].Formula:C28H28F6N4OColor and Shape:SolidMolecular weight:550.54(R)-Bambuterol
CAS:Bambuterol is a β2-agonist prodrug for asthma and COPD, taken daily, with a good safety profile and reduces plasma LDL-C and cholesterol.Formula:C18H29N3O5Color and Shape:SolidMolecular weight:367.44AZD-2207
CAS:AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes mellitus and obesity.Formula:C25H25Cl2F3N4O4SColor and Shape:SolidMolecular weight:605.46Cannabicitran
CAS:Cannabicitran is a cannabinoid that can decrease rabbits intraocular pressure [1] [2].Formula:C21H30O2Color and Shape:SolidMolecular weight:314.46FR-171113
CAS:Protease-activated receptor 1 antagonistFormula:C19H11Cl3N2O4SPurity:98%Color and Shape:SolidMolecular weight:469.73Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Formula:C29H39ClN2O6Purity:99.75%Color and Shape:SolidMolecular weight:547.08ADR-851 HCl
CAS:ADR-851 HCl is an HT3 receptor antagonist. It works against mechanical, acute thermal, and formalin-induced inflammatory pain.Formula:C14H19Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:332.23VUF8504
CAS:VUF8504 is a novel ligand of adenosine A3 receptor.Formula:C22H17N3O2Color and Shape:SolidMolecular weight:355.39E2508
CAS:E2508 is a selective antagonist of corticotropin-releasing factor 1 receptor.Formula:C36H47N3O7SPurity:98%Color and Shape:SolidMolecular weight:665.84Trimipramine
CAS:Trimipramine is an antidepressant with an anxiety-reducing sedative component to its action.Formula:C20H26N2Purity:98%Color and Shape:SolidMolecular weight:294.43BL 6341A
CAS:BL 6341A is related to Tumor data and H2-antagonists or anti-histaminsFormula:C9H14N8OS3Color and Shape:SolidMolecular weight:346.46FR 139317
CAS:highly potent and selective ETA endothelin receptor antagonistFormula:C33H44N6O5Purity:98%Color and Shape:SolidMolecular weight:604.74Carbuterol hydrochloride
CAS:Carbuterol hydrochloride is a short-acting β2 adrenoreceptor agonist.Formula:C13H22ClN3O3Color and Shape:SolidMolecular weight:303.79S-22153
CAS:<p>S22153 is an antagonist of melatonin receptor.</p>Formula:C14H17NOSColor and Shape:SolidMolecular weight:247.36GR 128107
CAS:GR 128107 is an antagonist of melatonin receptor.Formula:C16H20N2O2Color and Shape:SolidMolecular weight:272.34Cgp 52608
CAS:CGP 52608 is a selective ligand for RAR-associated orphan receptor alpha.Formula:C8H12N4OS2Color and Shape:SolidMolecular weight:244.34HAMI 3379
CAS:HAMI 3379 (HAMI3379) is a CysLT2 antagonist that attenuates brain damage and inhibits microglia inflammation following focal cerebral ischemia in rats.Formula:C34H45NO8Purity:99.75%Color and Shape:SolidMolecular weight:595.72PF-06412154 HCl
CAS:PF-06412154 HCl is a glucagon receptor antagonist.Formula:C24H28ClN3O3Color and Shape:SolidMolecular weight:441.96Thromboxane B2
CAS:Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces platelet aggregation and arterial contraction.Formula:C20H34O6Color and Shape:SolidMolecular weight:370.48Benzamide Derivative 1
CAS:Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Formula:C22H34ClN3O3Purity:>99.99%Color and Shape:SolidMolecular weight:423.98Clenproperol
CAS:Clenproperol is a β2-adrenergic agonist.Formula:C11H16Cl2N2OColor and Shape:SolidMolecular weight:263.16PF-04628935
CAS:PF-04628935: potent GHS-R1a antagonist/inverse agonist, IC50=4.6 nM, orally bioavailable, brain penetrant.Formula:C24H26ClN7OSPurity:98%Color and Shape:SolidMolecular weight:496.03OUP-186
CAS:OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.Formula:C19H30ClN3SColor and Shape:SolidMolecular weight:367.98(2R,3R)-E1R
CAS:(2R,3R)-E1R is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.Formula:C13H16N2O2Purity:98%Color and Shape:SolidMolecular weight:232.28Prostaglandin D2
CAS:<p>Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.</p>Formula:C20H32O5Purity:>99.99%Color and Shape:SolidMolecular weight:352.47Amosulalol, (+)-
CAS:Amosulalol, (+)-, is an adrenergic agent.Formula:C18H24N2O5SColor and Shape:SolidMolecular weight:380.46CP-122721
CAS:CP-122721: NK1 receptor blocker, has antidepressant, anti-anxiety, antiemetic effects, and selectively inhibits substance P receptors.Formula:C20H23F3N2O2Color and Shape:SolidMolecular weight:380.4Zinterol
CAS:<p>Zinterol is a potent and selective agonist of β2-adrenoceptor. Zinterol increases ICa in a concentration-dependent manner(EC50 of 2.2 nM).</p>Formula:C19H26N2O4SPurity:98%Color and Shape:SolidMolecular weight:378.49Z-335 sodium
CAS:Z-335 Salt, a thromboxane A2 receptor antagonist, is used potentially for the treatment of arterial occlusive disease.Formula:C18H18ClNNaO4SColor and Shape:SolidMolecular weight:402.84YM-430
CAS:YM-430: β1 blocker & Ca²⁺ channel antagonist; antianginal & antihypertensive; IC50: 59.2 nM (rhythmic contractions), 36.6 mg/kg in rats (ST depression).Formula:C29H35N3O8Purity:98%Color and Shape:SolidMolecular weight:553.6Pirepemat fumarate
CAS:Pirepemat fumarate (IRL752), aids Parkinson's research, boosts cognition and cortical catecholamine transmission.Formula:C15H17F2NO5Color and Shape:SolidMolecular weight:329.3U-101958 Maleate
CAS:U-101958 Maleate binds to dopamine D4 and sigma1 receptors with high affinity in neuroblastoma cells and human cerebellum.Formula:C25H33N3O5Purity:98%Color and Shape:SolidMolecular weight:455.55NGD 98-2
CAS:NGD 98-2 is a new generation, topology 2 selective orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.Formula:C19H24F3N3O3Color and Shape:SolidMolecular weight:399.41Trimazosin hydrochloride
CAS:Trimazosin hydrochloride is used in the treatment of hypertensive patients failing to respond to thiazides.Formula:C20H32ClN5O7Color and Shape:SolidMolecular weight:489.95mCPBG
CAS:mCPBG is a potent high affinity agonist of 5-HT3 receptor.Formula:C8H10ClN5Color and Shape:SolidMolecular weight:211.65ChemR23-IN-2
CAS:ChemR23-IN-2 is a potent, orally active inhibitor of ChemR23 (IC50: 3.2 nM).Formula:C29H26N4O5Color and Shape:SolidMolecular weight:510.54RX821002
CAS:RX821002: potent α2-adrenoceptor antagonist, selective for α2D (pKd 9.7) over α2A (pKd 8.2), low affinity for imidazoline.Formula:C12H14N2O3Purity:98%Color and Shape:SolidMolecular weight:234.25GTS-21
CAS:GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.Formula:C19H20N2O2Purity:98%Color and Shape:SolidMolecular weight:308.37(R)-Azelastine
CAS:(R)-Azelastine, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.Formula:C22H24ClN3OColor and Shape:SolidMolecular weight:381.9TP-680
CAS:TP-680 is a antagonist of cholecystokininA receptor.Formula:C35H33N5O4SPurity:98%Color and Shape:SolidMolecular weight:619.73Eptapirone fumarate
CAS:Eptapirone (F11440) is a strong 5HT1A agonist with high anxiolytic and antidepressant effects, more potent than buspirone and flesinoxan.Formula:C20H27N7O6Color and Shape:SolidMolecular weight:461.479Abanoquil
CAS:Abanoquil is an antagonist of alpha-1 adrenoceptor.Formula:C22H25N3O4Color and Shape:SolidMolecular weight:395.45Metitepine
CAS:Metitepine is a serotonin receptor antagonist in the CNS used as an antipsychotic.Formula:C20H24N2S2Color and Shape:SolidMolecular weight:356.55

