GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5964 products of "GPCR/G-Protein"
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Vilanterol
CAS:Vilanterol is a selective long-acting beta2-adrenergic agonist (LABA) used in the treatment of COPD and asthma.Formula:C24H33Cl2NO5Purity:97.47% - 99.46%Color and Shape:SolidMolecular weight:486.43Ref: TM-T2645
1mg42.00€5mg88.00€10mg120.00€25mg183.00€50mg240.00€100mg358.00€200mg532.00€1mL*10mM (DMSO)95.00€Nadolol
CAS:Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.Formula:C17H27NO4Purity:99.87% - 99.92%Color and Shape:White To Off-White Crystalline Powder SolidMolecular weight:309.40Esprolol
CAS:Esprolol (ACC-9369 free base) is a novel beta-adrenergic antagonist used to study exertional angina.Formula:C17H27NO4Purity:71.58% - 99.16%Color and Shape:SoildMolecular weight:309.4Ref: TM-T27286L
1mg80.00€2mg105.00€5mg172.00€10mg253.00€25mg414.00€50mg583.00€100mg783.00€200mg1,054.00€PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
PACAP (6-27) is an antagonist for PACAP receptors with varying IC50s; blocks cAMP in neuroblastoma and breast cancer cells.Color and Shape:LiquidPA-8
CAS:PA-8: Selective PAC1 antagonist, orally active, blocks CREB phosphorylation & cAMP increase (IC50=2nM), reduces pain & aversive response in vivo.Formula:C17H18N4O4Purity:97.54%Color and Shape:SolidMolecular weight:342.35PACAP (6-38), human, ovine, rat acetate
PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptorFormula:C184H303N55O48SPurity:99.84%Color and Shape:SoildMolecular weight:4085.84TAK-448 acetate
CAS:TAK-448 acetate (MVT-602 acetate) is a KISS1R agonist, a synthetic peptide similar to kisspeptin.Formula:C60H84N16O16Purity:99.88%Color and Shape:SolidMolecular weight:1285.41KSK94 FA
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.Formula:C26H28N4O3Purity:97.51%Color and Shape:SoildMolecular weight:444.53BAM (8-22) acetate
BAM (8-22) acetate, a proenkephalin A derivative, stimulates MrgprC11, hMrgprX1, and causes scratching in mice.Formula:C93H131N25O25SPurity:98.85%Color and Shape:SolidMolecular weight:2031.25Cholecystokinin (26-33) free acid
CAS:Cholecystokinin (26-33) free acid is part of CCK and induces mild taste aversion conditioning in rats.Formula:C49H61N9O14S2Purity:99.14%Color and Shape:SoildMolecular weight:1064.19Adatanserin hydrochloride
CAS:Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formula:C21H32ClN5OPurity:99.64%Color and Shape:SolidMolecular weight:405.96Binospirone
CAS:Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formula:C20H26N2O4Purity:97.57% - 98.96%Color and Shape:SoildMolecular weight:358.43Ref: TM-T71138L
1mg115.00€5mg275.00€10mg394.00€25mg615.00€50mg848.00€100mg1,121.00€200mg1,539.00€1mL*10mM (DMSO)34.00€Lanepitant 2HCl
CAS:Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist that can be used to study painful neuropathy-like disorders such as migraine.Formula:C33H47Cl2N5O3Purity:98.67%Color and Shape:SolidMolecular weight:632.66Org 13011
CAS:Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Formula:C18H25F3N4OPurity:98.02%Color and Shape:SoildMolecular weight:370.41Ref: TM-T28258L
1mg115.00€5mg275.00€10mg394.00€25mg615.00€50mg848.00€100mg1,121.00€200mg1,510.00€1mL*10mM (DMSO)281.00€KB-5492 FA
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS 번호128-52-56-8Formula:C24H32N2O8Purity:98.12%Color and Shape:SolidMolecular weight:476.52Pobilukast
CAS:Pobilukast (SKF 104353) is a cysteinyl leukotriene receptor antagonist that can be used to study limiting myocardial injury in MI/R rats.Formula:C26H34O5SPurity:99.65% - 99.84%Color and Shape:SolidMolecular weight:458.61BM213 acetate
BM213 acetate is a selective C5aR1 agonist with antitumor activity that induces C5aR1-mediated calcium mobilization and pERK1/2 signaling.
Formula:C45H74N12O12Purity:99.88%Color and Shape:SolidMolecular weight:975.14MRGPRX4 modulator-2
CAS:MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM. Its notable applications include research on autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson's Syndrome, and various chronic itch conditions [1].Formula:C15H9ClF4O3Purity:99.24%Color and Shape:SolidMolecular weight:348.68Acrivastine D7
CAS:Acrivastine D7 is a deuterium labeled Acrivastine. Acrivastine is a short acting antagonist of histamine 1 receptor.Formula:C22H24N2O2Purity:98%Color and Shape:SolidMolecular weight:355.48Etofylline clofibrate
CAS:Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.Formula:C19H21ClN4O5Color and Shape:SolidMolecular weight:420.854-(4-Chlorobenzyl)phthalazin-1(2H)-one
CAS:4-(4-Chlorobenzyl)phthalazin-1(2H)-one is a useful organic compound for research related to life sciences. The catalog number is T67610 and the CAS number is 53242-88-9.Formula:C15H11ClN2OColor and Shape:SolidMolecular weight:270.72Quetiapine-d8 Hemifumarate
CAS:Quetiapine-d8 Hemifumarate is a deuterated compound of Quetiapine Hemifumarate. Quetiapine Hemifumarate has a CAS number of 111974-72-2. Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.Formula:C25H21D8N3O6SColor and Shape:SolidMolecular weight:507.63Ramelteon-d5
CAS:Ramelteon-d5 is a deuterated compound of Ramelteon.Formula:C16H16D5NO2Color and Shape:SolidMolecular weight:264.37Pramipexole dihydrochloride
CAS:Pramipexole dihydrochloride could be used to treat Parkinson disease.Formula:C10H18ClN3SPurity:98%Color and Shape:White Crystalline PowderMolecular weight:247.79Agomelatine (L(+)-Tartaric acid)
CAS:Agomelatine (L(+)-Tartaric acid) is an MT1/MT2 agonist and selective 5-HT2C antagonist, supporting melatonergic and serotonergic signaling studies in neuroscience.Formula:C19H23NO8Purity:99.79%Color and Shape:SolidMolecular weight:393.393-Hydroxy agomelatine
CAS:3-Hydroxy agomelatine (3-Hydroxyagomelatine) is a 5-HT2C receptor antagonist used in the study of neurological disorders.Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3Asenapine
CAS:Asenapine (Org 5222) is a 5-HT receptor, adrenergic receptor, and histamine receptor antagonist with antipsychotic properties for the treatment of schizophreniaFormula:C17H16ClNOPurity:99.64%Color and Shape:CoaMolecular weight:285.77SYL-4
CAS:SYL-4 is a potential P2Y12 receptor antagonist with a Ki value of 7.35 ± 1.72 for use in synthetic dyes.Formula:C20H15N3O5SPurity:95.76%Color and Shape:SoildMolecular weight:409.42rac-Propranolol-d7
CAS:Rac-Propranolol-d7 is the deuterated form of Rac-Propranolol. Propranolol is a β-adrenergic receptor antagonist that inhibits β1AR.Formula:C16H14D7NO2Color and Shape:SolidMolecular weight:266.39PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Formula:C32H36N6O5Purity:99.00%Color and Shape:SolidMolecular weight:584.67TP-16
CAS:TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
Formula:C24H22FNO4SPurity:98.53% - 99.15%Color and Shape:SolidMolecular weight:439.5BMS-986224
CAS:BMS-986224 is an orally active, potent and selective APJ receptor agonist.BMS-986224 is a candidate compound for the treatment of heart failure.
Formula:C24H23ClN4O6Purity:98.61% - 99.67%Color and Shape:SolidMolecular weight:498.92cis-(Z)-Flupentixol dihydrochloride
CAS:cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.Formula:C23H27Cl2F3N2OSPurity:98.07%Color and Shape:SolidMolecular weight:507.44Omidenepag
CAS:Omidenepag (UR-7276) is an EP2 agonist and a novel topical ocular hypotensive agent.Omidenepag can be used to study glaucoma and hypertension.Formula:C23H22N6O4SPurity:99.67% - 99.77%Color and Shape:SolidMolecular weight:478.52Furprofen
CAS:Furprofen, an NSAID, inhibits PGE synthesis, offers analgesic effects, and is orally taken for pain relief.Formula:C14H12O4Purity:98.62% - 99.25%Color and Shape:SolidMolecular weight:244.24Asenapine hydrochloride
CAS:Asenapine hydrochloride (Org 5222 hydrochloride) is an antagonist of 5-hydroxytryptamine, adrenergic, dopamine, and histamine receptors with antipsychotic effects.Formula:C17H17Cl2NOColor and Shape:SolidMolecular weight:322.23V-0219
CAS:V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.Formula:C20H25F3N4O2Purity:99.91%Color and Shape:SoildMolecular weight:410.43Tegaserod
CAS:Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).Formula:C16H23N5OPurity:99.20% - 99.89%Color and Shape:SolidMolecular weight:301.39Argipressin
CAS:Argipressin is a vasoconstrictive and antidiuretic hormone, binding to V1 receptors with Kd ~1.4 nM in rat heart and aortic cells.Formula:C46H65N15O12S2Purity:98%Color and Shape:White PowderMolecular weight:1084.23Sumanirole maleate
CAS:Sumanirole maleate (PNU-95666E) is a D2 receptor full agonist with high selectivity that plays a vital role in Parkinson's disease and restless leg syndrome.Formula:C15H17N3O5Purity:98%Color and Shape:SolidMolecular weight:319.31L-798106
CAS:L-798106 (CM9) is an EP3 receptor antagonist that inhibits EP4, EP1, and EP2 receptors and attenuates PGE2-induced cough.Formula:C27H22BrNO4SPurity:98.97%Color and Shape:SolidMolecular weight:536.44Lanreotide
CAS:Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours.Formula:C54H69N11O10S2Color and Shape:SolidMolecular weight:1096.32Clothiapine
CAS:Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.Formula:C18H18ClN3SPurity:99.93%Color and Shape:SolidMolecular weight:343.87Zilpaterol-d7
CAS:Zilpaterol-d7 (trans-(±)-Zilpaterol-d7) is a deuterium-labeled version of Zilpaterol, a β-adrenergic receptor agonist.Formula:C14H12D7N3O2Color and Shape:SolidMolecular weight:268.36Docosahexaenoic acid ethyl ester
CAS:Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina or neurons.Formula:C24H36O2Purity:98.35%Color and Shape:SolidMolecular weight:356.54MRS-3777 hemioxalate
CAS:MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.
Formula:C17H19N5OC2H2O4Purity:97.10%Color and Shape:SolidMolecular weight:354.39GRK2 Inhibitor
CAS:GRK2 Inhibitor is an inhibitor of β-Adrenergic Receptor Kinase 1 (β ARK1).Formula:C12H9NO6Color and Shape:SolidMolecular weight:263.2Granisetron
CAS:Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
Formula:C18H24N4OColor and Shape:SolidMolecular weight:312.41Taranabant racemate
CAS:Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.Formula:C27H25ClF3N3O2Purity:98%Color and Shape:SolidMolecular weight:515.95UCSF924
CAS:UCSF924 is a potent and specific agonist of dopamine D4 receptor (DRD4) partial (EC50: 4.2 nM, Ki: 3 nM).Formula:C20H22N2O2Purity:98%Color and Shape:SolidMolecular weight:322.4
