GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,017 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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GR 55562 dihydrochloride
CAS:5-HT1B (5-HT1Dβ) silent antagonistFormula:C23H27Cl2N3O2Purity:99.45%Color and Shape:SolidMolecular weight:448.39Nexopamil racemate
CAS:Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.Formula:C24H40N2O3Purity:98.61%Color and Shape:SolidMolecular weight:404.59(R)-SLV 319
CAS:(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.Formula:C23H20Cl2N4O2SColor and Shape:SolidMolecular weight:487.4GBR 13069 dihydrochloride
CAS:GBR 13069 dihydrochloride is a dopamine uptake inhibitor.Formula:C28H32Cl2F2N2OPurity:98%Color and Shape:SolidMolecular weight:521.47CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Formula:C20H16FN5O3SPurity:99.13%Color and Shape:SolidMolecular weight:425.44Ref: TM-T10710
1mg101.00€5mg241.00€10mg402.00€25mg727.00€50mg1,046.00€100mg1,525.00€1mL*10mM (DMSO)265.00€CB1/2 agonist 2
CAS:CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.Formula:C26H43NO3Color and Shape:SolidMolecular weight:417.62PNU-96391
CAS:PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.Formula:C15H23NO2SPurity:99.53%Color and Shape:SolidMolecular weight:281.41Ref: TM-T28435
1mg73.00€5mg146.00€10mg210.00€25mg319.00€50mg447.00€100mg600.00€200mg800.00€1mL*10mM (DMSO)138.00€YM022
CAS:YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.Formula:C32H28N4O3Purity:98%Color and Shape:SolidMolecular weight:516.59Afurolol Hydrochloride
CAS:Afurolol Hydrochloride (DL 071-IT) is a non-selective β-adrenergic receptor antagonist. DL 071 IT exhibits intrinsic sympathomimetic activity.Formula:C15H22ClNO4Purity:98.86%Color and Shape:SolidMolecular weight:315.79QCC-374
CAS:QCC-374 is a prostanoid agonist. It potentially for the treatment of pulmonary arterial hypertension.Formula:C28H33N3O2Purity:98%Color and Shape:SolidMolecular weight:443.58S 16924
CAS:S 16924 is a 5-HT 1A agonist with potential anxiolytic effects and may be useful in the study of neurologic disorders.Formula:C22H24FNO4Purity:99.35% - 99.6%Color and Shape:SolidMolecular weight:385.43UK 1745
CAS:UK 1745 is a novel drug of cardiotonic.Formula:C16H23ClN2O2Color and Shape:SolidMolecular weight:310.82CP-195543
CAS:CP-195543 is an effective leukotriene B4 antagonist for the treatment of inflammatory diseases.Formula:C24H19F3O4Color and Shape:SolidMolecular weight:428.4VNA-932
CAS:VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).Formula:C23H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:402.88Levobunolol hydrochloride
CAS:Levobunolol hydrochloride 是一种非选择性的 β-肾上腺素受体阻滞剂，可用于治疗青光眼和上斜肌肌障碍的研究。Formula:C17H26ClNO3Purity:98.49% - >99.99%Color and Shape:SolidMolecular weight:327.85WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurity:98%Color and Shape:SolidMolecular weight:519.52Tecalcet Hydrochloride
CAS:Tecalcet Hydrochloride, an allosteric CaSR modulator, enhances extracellular Ca2+ sensitivity.Formula:C18H23Cl2NOPurity:99.97%Color and Shape:SolidMolecular weight:340.29Ref: TM-T13918
2mg34.00€5mg47.00€10mg72.00€25mg146.00€50mg230.00€100mg335.00€200mgTo inquire1mL*10mM (DMSO)52.00€GR 128107
CAS:GR 128107 is an antagonist of melatonin receptor.Formula:C16H20N2O2Color and Shape:SolidMolecular weight:272.34C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Formula:C27H43Cl2N5O2Purity:98.67%Color and Shape:SolidMolecular weight:540.57ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formula:C20H23N3OSPurity:97.17%Color and Shape:SolidMolecular weight:353.48VUF-10497
CAS:VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).Formula:C18H20ClN5SPurity:98%Color and Shape:SolidMolecular weight:373.9CCR4 antagonist 3-1
CAS:CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.
Formula:C14H12N2SPurity:99.53%Color and Shape:SolidMolecular weight:240.32SB-269970
CAS:SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49SMANT hydrochloride
CAS:SMANT hydrochloride (N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride) is an antagonist of Smoothened accumulation.Formula:C16H24BrClN2OPurity:99.81%Color and Shape:SolidMolecular weight:375.73Guanethidine
CAS:Guanethidine sulphate, made in 1959, lowers blood pressure by disrupting neurotransmitters in sympathetic nerves.Formula:C10H22N4Color and Shape:SolidMolecular weight:198.31EP4 receptor antagonist 4
CAS:EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1].Formula:C19H14N2OSColor and Shape:SolidMolecular weight:318.395-HT3 antagonist 2
CAS:5-HT3 antagonist 2 is an antagonist of 5-HT3 receptor.Formula:C18H21N3OPurity:98%Color and Shape:SolidMolecular weight:295.38(R)-V-0219
(R)-V-0219: GLP-1R PAM, orally active, triggers Ca++ flux in HEK-hGLP-1R cells.Formula:C20H25F3N4O2Color and Shape:SolidMolecular weight:410.43NGB 2904 hydrochloride
CAS:dopamine D3 receptor antagonistFormula:C28H30Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:530.92Ono 1301
CAS:Ono 1301 mimics prostaglandin I2, inhibits thromboxane A2 synthase, reduces pancreatic fibrosis, and boosts cAMP via IP receptor.Formula:C26H24N2O4Color and Shape:SolidMolecular weight:428.48CVT-2759
CAS:CVT-2759, potential A(1)-ADOR partial agonist, could slow ventricular rate without severe cardiac side effects.Formula:C17H24N6O6Color and Shape:SolidMolecular weight:408.41Bepotastine tosylate
CAS:Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.Formula:C28H33ClN2O6SColor and Shape:SolidMolecular weight:561.09Monatepil maleate
CAS:Monatepil maleate (AJ-2615 maleate) is a Ca2+-channel and α1-adrenergic receptor antagonist, and ACAT inhibitor with antihypertensive activity.Formula:C32H34FN3O5SPurity:97.90%Color and Shape:SolidMolecular weight:591.69CCX777
CAS:CCX777 is a partial agonist recruited to ACKR3 by β-arrestin-2 and is used in cancer research.Formula:C31H43N7O3SPurity:98.73%Color and Shape:SolidMolecular weight:593.78A2AR-agonist-1
CAS:A2AR-agonist-1 targets A2A Receptor/ENT1 for neuroprotection; potent with Ki of 4.39 (A2AR), 3.47 (ENT1).Formula:C20H22N6O4Purity:99.9%Color and Shape:SolidMolecular weight:410.43Ref: TM-T10212
1mg90.00€2mg127.00€5mg178.00€10mg269.00€25mg427.00€50mg610.00€100mg820.00€500mg1,603.00€1mL*10mM (DMSO)207.00€Argtide
CAS:Argtide is an luteinizing hormone releasing hormone (LHRH) antagonist.Formula:C80H104ClN21O14Color and Shape:SolidMolecular weight:1619.27L-365260
CAS:L-365260 is a nonpeptide gastrin and cerebral cholecystokinin receptor (CCK-B) antagonist used in the study of neurologic ojibwa and endocrine diseases.Formula:C24H22N4O2Purity:99.75%Color and Shape:SolidMolecular weight:398.46SCH-23390 maleate
CAS:SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,Formula:C21H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:403.86Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Formula:C29H39ClN2O6Purity:99.75%Color and Shape:SolidMolecular weight:547.08GALNON
CAS:Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue propertiesFormula:C40H46N4O6Purity:98%Color and Shape:SolidMolecular weight:678.822-Methylthioadenosine diphosphate trisodium
CAS:2-Methylthioadenosine diphosphate trisodium(2-MeS-ADP) is a purinergic P2Y receptor agonist that agonizes P2Y13 and P2Y12, induces platelet aggregation.Formula:C11H14N5Na3O10P2SColor and Shape:SolidMolecular weight:539.24L-692585
CAS:ghrelin receptor (GHS-R1a) agonistFormula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.68A 55453
CAS:A 55453 is a radiated ionophore used as a reversibl, high-affinity alpha 1-adrenergic receptor probe.Formula:C25H32N6O3Color and Shape:SolidMolecular weight:464.56Sigma-LIGAND-1
CAS:Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively.Formula:C27H33NO4Purity:99.89%Color and Shape:SolidMolecular weight:435.56Ref: TM-T13510
1mg46.00€5mg99.00€10mg147.00€25mg222.00€50mg299.00€100mg411.00€200mg553.00€1mL*10mM (DMSO)113.00€Belaperidone
CAS:Belaperidone, an antipsychotic, resembles clozapine, binds D(4) and 5-HT(2A) receptors, minimally extends Q-T without causing arrhythmias.Formula:C22H22FN3O2Color and Shape:SolidMolecular weight:379.43Dicarbine
CAS:Double carbene blocks dopamine receptors, aiding schizophrenia and alcoholism research; it maintains defense reflexes despite mid-brain stimulation.Formula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3LRH-1 Inhibitor-3
CAS:LRH-1 Inhibitor-3 is an antagonist that inhibits LRH-1 transcriptional activity, reducing SHP, cyclin E1 (CCNE1), and G0S2,antiproliferation anticancer.Formula:C23H25N3O2Purity:98%Color and Shape:SolidMolecular weight:375.46Isamoltane hemifumarate
CAS:5-HT1B antagonistFormula:C16H22N202C4H404Purity:98%Color and Shape:SolidMolecular weight:332.4Aganepag
CAS:Aganepag: Potent EP2 agonist, EC50 0.19 nM, inactive at EP4, used in wound healing and scar/wrinkle treatment research.Formula:C24H31NO4SPurity:98%Color and Shape:SolidMolecular weight:429.57PF-03654746 Tosylate
CAS:PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration.Formula:C25H32F2N2O4SPurity:98%Color and Shape:SolidMolecular weight:494.6
