GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,023 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5986 products of "GPCR/G-Protein"
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Fenmetozole Tosylate
CAS:Fenmetozole Tosylate , acts as an antidepressant drug. is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor,Formula:C17H18Cl2N2O4SPurity:98%Color and Shape:SolidMolecular weight:417.31TH-162
CAS:TH-162 (R)-PIA is an A1 adenosine receptor agonist with ~100× higher affinity than its (+)-isomer.Formula:C19H23N5O4Color and Shape:SolidMolecular weight:385.42Agroclavine
CAS:Agroclavine is a clavine type of ergot alkaloid with D1 dopamine and a-adrenoceptor agonistic properties.Formula:C16H18N2Color and Shape:SolidMolecular weight:238.33RUSKI-201
CAS:RUSKI-201 is the first selective Hedgehog acyltransferase (Hhat) chemical probe in cells.Formula:C20H27N3OSColor and Shape:SolidMolecular weight:357.51RUSKI-201 dihydrochloride
CAS:RUSKI-201 dihydrochloride: potent Hhat inhibitor (IC50: 0.20 μM), blocks Hh signaling, and inhibits Hh palmitoylation.Formula:C20H29Cl2N3OSColor and Shape:SolidMolecular weight:430.43SKF 83959 hydrobromide
CAS:SKF 83959 hydrobromide is a Dopamine D1-like receptor partial agonist.Formula:C18H21BrClNO2Purity:98%Color and Shape:SolidMolecular weight:398.72R(+)-6-Bromo-APB HBr
CAS:R(+)-6-Bromo-APB HBr is used as a D1 Dopamine receptor agonist.Formula:C19H21Br2NO2Purity:98%Color and Shape:SolidMolecular weight:455.18SGS518 oxalate
CAS:SGS518 oxalate is a 5-HT6 antagonist.Formula:C23H24F2N2O7SPurity:98%Color and Shape:SolidMolecular weight:510.51LY 344864 S-enantiomer
CAS:LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42GLP-1R agonist 1
CAS:GLP-1R agonist 1, an imidazole derivative and potent GLP-1R activator, may aid diabetes research.Formula:C32H29ClFN3O5Color and Shape:SolidMolecular weight:590.04PGD2-IN-1
CAS:PGD2-IN-1 (PGD2-inhibitor) is an effective DP receptor antagonist (IC50:0.3 nM), a compound that can inhibit prostaglandin D2 (PGD2) signaling.Formula:C23H23Cl2N3O3Purity:98.21%Color and Shape:SolidMolecular weight:460.35Ref: TM-T4624
1mg66.00€5mg150.00€1mL*10mM (DMSO)159.00€10mg245.00€25mg414.00€50mg610.00€100mg867.00€500mg1,738.00€Felypressin acetate
CAS:Felypressin acetate (PLV-2) is an agonist of vasopressin 1 and acts on all arginine vasopressin receptors 1AS.Formula:C48H69N13O13S2Purity:97.06%Color and Shape:SolidMolecular weight:1100.27(Rac)-SEP-363856
CAS:(Rac)-SEP-363856 is the racemate of SEP-363856. SEP-363856 is an orally active and CNS active psychotropic agent with a uniqueFormula:C9H13NOSPurity:98%Color and Shape:SolidMolecular weight:183.27COR 170
CAS:inverse agonist of CB2 receptorsFormula:C31H36N2O2Purity:98%Color and Shape:SolidMolecular weight:468.63CB1/2 agonist 2
CAS:CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.Formula:C26H43NO3Color and Shape:SolidMolecular weight:417.62Pronethalol hydrochloride
CAS:β-adrenergic antagonistFormula:C15H20ClNOPurity:98%Color and Shape:SolidMolecular weight:265.78Naminterol
CAS:Naminterol is a phenethanolamine derivative is an agonist of β2 adrenoceptor with bronchodilatory properties, and used for treatment of asthma.Formula:C19H26N2O3Purity:98%Color and Shape:SolidMolecular weight:330.42MRS 1523
CAS:MRS 1523: selective adenosine A3 antagonist, Ki 18.9/113 nM (human/rat), blocks N-type Ca channels & inhibits action potentials in rat DRG neurons.Formula:C23H29NO3SPurity:98%Color and Shape:SolidMolecular weight:399.55JNJ-26070109
CAS:JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.Formula:C23H17BrF2N4O3SPurity:98%Color and Shape:SolidMolecular weight:547.37(Rac)-E1R
CAS:(Rac)-E1R is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric (Sig1R PAM) modulator of for the treatment of cognition/memory disorders.Formula:C13H16N2O2Purity:98%Color and Shape:SolidMolecular weight:232.28Bopindolol fumarate
CAS:Bopindolol fumarate: non-selective β1/β2-adrenoceptor blocker, partial agonist, low β3 affinity, treats hypertension.Formula:C27H32N2O7Color and Shape:SolidMolecular weight:496.56GSK 189254 HCl
CAS:GSK 189254A: histamine H3 antagonist, treats narcolepsy, may improve cognition and help with dementia, neuropathic pain.Formula:C21H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:387.9I-SAP
CAS:I-SAP: TP receptor blocker, alters platelet shape without causing clumping, EC50 9.7 nM, max binding pH 6.5-7.4, Kd 468-490 pM.Formula:C22H30INO4SColor and Shape:SolidMolecular weight:531.45SUN-C5174
CAS:"SUN-C5174 is a selective 5-HT2 antagonist with pA2=8.98; inhibits platelet aggregation and reduces thromboembolic death in mice at ≥0.3 mg/kg."Formula:C22H29FN4O2Purity:98%Color and Shape:SolidMolecular weight:400.49Tertatolol
CAS:Tertatolol is an effective antagonist of beta-adrenoceptor and 5-HT receptors.Formula:C16H25NO2SPurity:98%Color and Shape:SolidMolecular weight:295.44PD-89211
CAS:PD 89211 selectively blocks dopamine D4.2 receptor >800x vs. other subtypes; reverses quinpirole effect in vitro (IC50 = 2.1 nM).Formula:C19H21ClN4OPurity:98%Color and Shape:SolidMolecular weight:356.85Resomelagon
CAS:Resomelagon (AP1189), an oral melanocortin receptor agonist, triggers Ca2+ and ERK1/2 activation; useful in obesity and inflammation studies.Formula:C14H14N6O2Color and Shape:SolidMolecular weight:298.3ONO-2952
CAS:ONO-2952, a selective TSPO antagonist with Ki: 0.33-9.30 nM, may treat irritable bowel syndrome, reducing stress without causing amnesia.Formula:C22H20ClFN2O2Purity:98%Color and Shape:SolidMolecular weight:398.86S-3608
CAS:S-3608 is an atypical dopamine agonist.Formula:C16H20ClN3OSColor and Shape:SolidMolecular weight:337.87Ipsapirone
CAS:Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.
Formula:C19H23N5O3SPurity:99.51%Color and Shape:SolidMolecular weight:401.48Panamesine
CAS:Panamesine (EMD 57445) is a high affinity receptor ligand for sigma (IC50: 6 nM) with potential for atypical antipsychotic studies.Formula:C23H26N2O6Color and Shape:SolidMolecular weight:426.46PGN36
CAS:PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).Formula:C21H23N3O3Color and Shape:SolidMolecular weight:365.43Methapyrilene
CAS:Methapyrilene is a histamine H1 antagonist with sedative action.Formula:C14H19N3SColor and Shape:Liquid Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:261.39Repirinast
CAS:Repirinast is a mediator release inhibitor. It is used to treat asthma.Formula:C20H21NO5Color and Shape:SolidMolecular weight:355.38R 121919 hydrochloride
CAS:CRF1 antagonist with Ki=3.5 nM, lowers stress-induced ACTH, has anxiolytic and antidepressant effects, orally bioavailable.Formula:C22H33ClN6Color and Shape:SolidMolecular weight:417.0L 760735
CAS:L 760735 is a NK1 receptor antagonist.Formula:C26H29ClF7N5O2Purity:98%Color and Shape:SolidMolecular weight:611.98FR260010
CAS:FR260010 is a novel potent serotonin 5-HT2C receptor antagonist.Formula:C22H19N5Color and Shape:SolidMolecular weight:353.42ADRA1D receptor antagonist 1 HCl
CAS:ADRA1D receptor antagonist 1 HCl is a selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity.Formula:C15H14Cl2N4OPurity:98.13%Color and Shape:SolidMolecular weight:337.2Trimazosin
CAS:Trimazosin, a quinazoline derivative and prazosin relative, lowers blood pressure by blocking alpha1-adrenoceptors.Formula:C20H29N5O6Color and Shape:SolidMolecular weight:435.47SMO-IN-3
CAS:SMO-IN-3: Strong SMO blocker, disrupts Hh pathway (IC50=34.09 nM), hinders Daoy cell growth, has anticancer properties.Formula:C27H25F4N3O2Color and Shape:SolidMolecular weight:499.55-HT6/5-HT2A receptor ligand-1
CAS:Compound 33 is a dual 5-HT6/5-HT2A antagonist with Ki values of 2 nM and 11 nM, respectively, useful in neuro/psychiatric research.Formula:C21H19FN2O2Color and Shape:SolidMolecular weight:350.39CM572
CAS:CM572 is a selective putative sigma-2 antagonist.Formula:C22H23FN4O2SColor and Shape:SolidMolecular weight:426.51Alaproclate
CAS:Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia.Formula:C13H18ClNO2Purity:98.29% - 98.64%Color and Shape:SolidMolecular weight:255.74CAY10680
CAS:CAY10680 inhibits MAO-B (IC50=34.9 nM) & A2A receptors (Ki=39.5 nM), sparing other adenosine types & MAO-A, may treat Parkinson's.Formula:C18H16N2O2SColor and Shape:SolidMolecular weight:324.4Immepip
CAS:Immepip, a H3 agonist, has been shown to attenuate cortical histamine release and is utilized in the research of neurological diseases.Formula:C9H15N3Color and Shape:SolidMolecular weight:165.24Phenyltoloxamine
CAS:Phenyltoloxamine (Bistrimin): antihistamine with sedative, analgesic properties, and Sigma-1 receptor affinity (Ki=160 nM).Formula:C17H21NOColor and Shape:SolidMolecular weight:255.35Prucalopride hydrochloride
CAS:Prucalopride hydrochloride is a selective agonist of the 5-HT4.Formula:C18H27Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:404.33(S)-SLV 319
CAS:Ibipinabant (SLV319), a potent CB1 antagonist, K i = 7.8 nM, >1000x selective over CB2, for obesity and diabetic research.Formula:C23H20Cl2N4O2SColor and Shape:SolidMolecular weight:487.4Primidolol
CAS:Primidolol is a beta adrenergic receptor antagonist and antihypertensive agent.Formula:C17H23N3O4Purity:98%Color and Shape:SolidMolecular weight:333.38CP 93129 dihydrochloride
CAS:5-HT1B agonist, potent and highly selectiveFormula:C12H14ClN3OPurity:98%Color and Shape:SolidMolecular weight:251.71
