GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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MRS2179 tetrasodium
CAS:competitive antagonist at P2Y1 receptorsFormula:C11H17N5Na4O9P2Purity:98%Color and Shape:SolidMolecular weight:517.19Trifluperidol HCl
CAS:Trifluperidol, a dopamine D2-receptor antagonist, is used to treat schizophrenia.Formula:C22H24ClF4NO2Color and Shape:SolidMolecular weight:445.88RBI-257 Maleate
CAS:RBI-257 Maleate is a highly potent selective ligand of dopamine D4 receptor.Formula:C25H32IN3O5Color and Shape:SolidMolecular weight:581.44Fenmetozole
CAS:Fenmetozole is an antagonist of the actions of ethanol.Formula:C10H10Cl2N2OColor and Shape:SolidMolecular weight:245.11SDZ NKT 343
CAS:human tachykinin NK1 receptor antagonistFormula:C33H33N5O5Purity:98%Color and Shape:SolidMolecular weight:579.65RB-005
CAS:RB-005 is a potent SK1 inhibitor with IC(50) of 3.6 μM, potentially treating proliferative diseases like hypertension and degrades SK1 in human cells.Formula:C21H35NOColor and Shape:SolidMolecular weight:317.51UCSF686
CAS:UCSF686, a UCSF678 analog, lacks 5-HT5A potency but keeps affinity for 5-HT1A, 5-HT2B, 5-HT7, and serves as a control.Formula:C14H19N3O2SColor and Shape:SolidMolecular weight:293.38Neladenoson dalanate HCl
CAS:Neladenoson dalanate HCl is a potent, selective, orally active partial agonist of adenosine A1 receptor (EC50: 0.1 nM).Formula:C35H35Cl2N7O4S2Purity:98%Color and Shape:SolidMolecular weight:752.73SSTR4 agonist 3
CAS:SSTR4 agonist 3 activates SSTR4 in the hippocampus and neocortex, aiding memory and learning, and shows potent pain relief in rodents.Formula:C18H24N4OSColor and Shape:SolidMolecular weight:344.47ATC0065 HCl
CAS:ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist.Formula:C25H31BrCl2F3N5OColor and Shape:SolidMolecular weight:625.35CL-184005
CAS:CL-184005 is a PAF inhibitor that blocks tumor necrosis factor synthesis and reduces spleen-associated TNF protein.Formula:C33H46NO7PSColor and Shape:SolidMolecular weight:631.76Clencyclohexerol
CAS:Clencyclohexerol, like clenbuterol, is a β-adrenoceptor agonist with potential in muscle disorders but poses cardiovascular risks at high doses.Formula:C14H20Cl2N2O2Color and Shape:SolidMolecular weight:319.23GLP-1R agonist 1
CAS:GLP-1R agonist 1, an imidazole derivative and potent GLP-1R activator, may aid diabetes research.Formula:C32H29ClFN3O5Color and Shape:SolidMolecular weight:590.04ML233
CAS:"ML233: potent apelin receptor agonist, EC50=3.7 μM, 21-fold selective over AT1 receptor."Formula:C19H21NO4SColor and Shape:SolidMolecular weight:359.44Ketotifen
CAS:Ketotifen: Oral H1 blocker & mast cell stabilizer, inhibits 6-phosphogluconate dehydrogenase, antiviral, for EAE & asthma prevention research.Formula:C19H19NOSColor and Shape:SolidMolecular weight:309.43CB1/2 agonist 2
CAS:CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.Formula:C26H43NO3Color and Shape:SolidMolecular weight:417.62MRS 1523
CAS:MRS 1523: selective adenosine A3 antagonist, Ki 18.9/113 nM (human/rat), blocks N-type Ca channels & inhibits action potentials in rat DRG neurons.Formula:C23H29NO3SPurity:98%Color and Shape:SolidMolecular weight:399.55JNJ-26070109
CAS:JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat.Formula:C23H17BrF2N4O3SPurity:98%Color and Shape:SolidMolecular weight:547.37Resomelagon
CAS:Resomelagon (AP1189), an oral melanocortin receptor agonist, triggers Ca2+ and ERK1/2 activation; useful in obesity and inflammation studies.Formula:C14H14N6O2Color and Shape:SolidMolecular weight:298.3ONO-2952
CAS:ONO-2952, a selective TSPO antagonist with Ki: 0.33-9.30 nM, may treat irritable bowel syndrome, reducing stress without causing amnesia.Formula:C22H20ClFN2O2Purity:98%Color and Shape:SolidMolecular weight:398.86Panamesine
CAS:Panamesine (EMD 57445) is a high affinity receptor ligand for sigma (IC50: 6 nM) with potential for atypical antipsychotic studies.Formula:C23H26N2O6Color and Shape:SolidMolecular weight:426.46(-)-S-Timolol
CAS:(-)-S-Timolol is an antagonist of the beta-Adrenergic .Formula:C13H26N4O4SColor and Shape:SolidMolecular weight:334.44Inupadenant
CAS:Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1].Formula:C25H26F2N8O4S2Color and Shape:SolidMolecular weight:604.65A3AR antagonist 1
CAS:A3AR antagonist 1 is a potent and selective human A3adenosine receptor (AR) antagonist (Ki: 4.63) and has no affinity for the rat A3AR.Formula:C32H24N4O4SColor and Shape:SolidMolecular weight:560.62FR260010
CAS:FR260010 is a novel potent serotonin 5-HT2C receptor antagonist.Formula:C22H19N5Color and Shape:SolidMolecular weight:353.42Trimazosin
CAS:Trimazosin, a quinazoline derivative and prazosin relative, lowers blood pressure by blocking alpha1-adrenoceptors.Formula:C20H29N5O6Color and Shape:SolidMolecular weight:435.47SMO-IN-3
CAS:SMO-IN-3: Strong SMO blocker, disrupts Hh pathway (IC50=34.09 nM), hinders Daoy cell growth, has anticancer properties.Formula:C27H25F4N3O2Color and Shape:SolidMolecular weight:499.5Monatepil maleate
CAS:Monatepil maleate (AJ-2615 maleate) is a Ca2+-channel and α1-adrenergic receptor antagonist, and ACAT inhibitor with antihypertensive activity.Formula:C32H34FN3O5SPurity:97.90%Color and Shape:SolidMolecular weight:591.69CAY10680
CAS:CAY10680 inhibits MAO-B (IC50=34.9 nM) & A2A receptors (Ki=39.5 nM), sparing other adenosine types & MAO-A, may treat Parkinson's.Formula:C18H16N2O2SColor and Shape:SolidMolecular weight:324.4FR-194921
CAS:FR-194921: potent oral adenosine A1 antagonist, improves cognition, reduces anxiety, similar efficacy in humans, rats, mice.Formula:C23H23N5OColor and Shape:SolidMolecular weight:385.46RP101442
CAS:RP101442: Ozanimod metabolite, selective S1PR1 agonist, EC50: 2.6 nM (S1PR1), 171 nM (S1PR5).Formula:C23H22N4O3Color and Shape:SolidMolecular weight:402.45ZM 169369
CAS:ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.Formula:C19H20N2SColor and Shape:SolidMolecular weight:308.44Prucalopride hydrochloride
CAS:Prucalopride hydrochloride is a selective agonist of the 5-HT4.Formula:C18H27Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:404.33CP 93129 dihydrochloride
CAS:5-HT1B agonist, potent and highly selectiveFormula:C12H14ClN3OPurity:98%Color and Shape:SolidMolecular weight:251.71CCG-2046
CAS:CCG-2046 is a chemical inhibitor targeting RGS4, demonstrating an inhibition concentration (IC50) of 4.3 μM for the interaction between RGS4 and Gαo signal.Formula:C11H10N4Color and Shape:SolidMolecular weight:198.22E-3620
CAS:E-3620 is a potent antagonist of the 5-HT3 receptor and can be used to study dyskinesia and gastrointestinal dysfunction.Formula:C20H27Cl2N3O2Purity:98.88% - 98.88%Color and Shape:SolidMolecular weight:412.35MRS2395
CAS:MRS2395, a dipivaloyl P2Y12 receptor blocker, inhibits ADP-induced platelet activation with a Ki of 3.6 μM and boosts TRAP-6-triggered dense granule release.Formula:C20H30ClN5O4Color and Shape:SolidMolecular weight:439.94PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.
Formula:C18H22ClF3N2O3SPurity:99.95%Color and Shape:SolidMolecular weight:438.89Oxyfedrine
CAS:Oxyfedrine: oral β-adrenoreceptor agonist, vasodilator for cardiovascular research.Formula:C19H23NO3Color and Shape:SolidMolecular weight:313.39GRK5-IN-3
CAS:GRK5-IN-3 is a covalent inhibitor of G protein-coupled receptor kinase 5 (GRK5).GRK5-IN-3 significantly inhibits GRK5 (IC50: 0.22 μM) and GRK6 (IC50: 0.41 μM).Formula:C23H21N7O3Color and Shape:SolidMolecular weight:443.46SSTR4 agonist 2
CAS:SSTR4 agonist 2, a potent SSTR4 subtype activator, may aid in researching nociceptive and inflammatory disorders.Formula:C18H24N4OColor and Shape:SolidMolecular weight:312.41Bag-1
CAS:Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.Formula:C22H27N3Color and Shape:SolidMolecular weight:333.47JNJ-17156516
CAS:JNJ-17156516 is a potent, and selective cholecystokinin 1 receptor antagonist.Formula:C26H22Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:481.37Adenosine receptor antagonist 2
CAS:Adenosine receptor antagonist 2 is an orally active A2a (IC50: 1 nM), A2b (IC50: 3 nM) adenosine receptor antagonist that exhibits antitumour effects.Formula:C23H21FN8OColor and Shape:SolidMolecular weight:444.46SKF-104557
CAS:N-Despropyl ropinirole, a ropinirole metabolite, enhances CHO cell acidification via D2/D3/D4 receptors; also a ropinirole impurity. EC50: 0.63-1.23 µM.Formula:C13H18N2OColor and Shape:SolidMolecular weight:218.29S-5751
CAS:S-5751, a prostanoid DP (DP1) antagonist, is used potentially for the treatment of bronchial asthma.Formula:C25H31NO4SColor and Shape:SolidMolecular weight:441.58Imiloxan hydrochloride
CAS:Imiloxan hydrochloride is an α2-adrenoceptor antagonist.Formula:C14H17ClN2O2Purity:98%Color and Shape:SolidMolecular weight:280.75Gastrazole disodium
CAS:Gastrazole, a CCK2 receptor antagonist, is used potentially for the treatment of pancreatic cancer.Formula:C34H34FN5Na2O7Color and Shape:SolidMolecular weight:689.652Methylcarbamyl PAF C-16
CAS:Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a PAF analog with PAF agonistic properties, activating inflammation in pregnancy tissues and promoting preterm birth.Formula:C26H55N2O7PColor and Shape:SolidMolecular weight:538.7SC 51089 free base
CAS:SC 51089 free base is a selective antagonist of the prostaglandin E2 EP1 receptor, demonstrating neuroprotective activity.Formula:C22H19ClN4O3Color and Shape:SolidMolecular weight:422.86
