GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,028 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(61 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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γ-Linolenic acid ethyl ester
CAS:γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B 4 receptor 4 (LTB 4 ) antagonist which has a potential anti-inflammatory effect[1].Formula:C20H34O2Color and Shape:SolidMolecular weight:306.48MM-22
CAS:biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamideFormula:C36H60N4O5SPurity:98%Color and Shape:SolidMolecular weight:660.95Alaproclate (hydrochloride)
CAS:Alaproclate, an SSRI, enhances serotonin and SIRT1, hinders NMDA and K+ currents in neurons, and shows antidepressant-like effects in rats.Formula:C13H19Cl2NO2Color and Shape:SolidMolecular weight:292.2Zometapine
CAS:Zometapine (CI 716) is an antidepressant compound that is a derivative of pyrazole and diazepine.Formula:C14H15ClN4Purity:98.87%Color and Shape:SolidMolecular weight:274.75PRX933 hydrochloride
CAS:PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.Formula:C16H22ClN5O2Purity:99.51% - 99.89%Color and Shape:SolidMolecular weight:351.84Ref: TM-T12565
1mg338.00€5mg538.00€1mL*10mM (DMSO)618.00€10mg858.00€25mg1,269.00€50mg1,720.00€100mg2,305.00€Levemopamil HCl
CAS:Levemopamil HCl is used as a calcium channel blocker.Formula:C23H31ClN2Purity:98%Color and Shape:SolidMolecular weight:370.96(S)-Viloxazine Hydrochloride
CAS:(S)-Viloxazine Hydrochloride is an S-isomer and NRI used as an antidepressant.Formula:C13H20ClNO3Purity:99.95%Color and Shape:SolidMolecular weight:273.76Ref: TM-T22420
1mg34.00€5mg63.00€1mL*10mM (DMSO)65.00€10mg85.00€25mg117.00€50mg168.00€100mg239.00€500mg592.00€Octahydroisoindole
CAS:Octahydroisoindole is a natural product and a reference standard.Formula:C8H15NPurity:≥98%Color and Shape:SolidMolecular weight:125.21SB 206553 hydrochloride
CAS:SB 206553 hydrochloride is a 5-HT2C inverse agonist and a 5-HT2C/5-HT2B receptor antagonist with anxiolytic activity, useful for studying neurological disordersFormula:C17H17ClN4OPurity:99.56%Color and Shape:SolidMolecular weight:328.8NVS-CRF38
CAS:NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1).Formula:C19H21N5O2Purity:98%Color and Shape:SolidMolecular weight:351.4Tranterol hydrochloride
CAS:Tranterol, a β2-adrenergic receptor agonist, is used potentially for the treatment of asthma.Formula:C13H19Cl2F3N2OPurity:98%Color and Shape:SolidMolecular weight:347.2AR-A 2
CAS:AR-A 2, a selective 5-HT1B antagonist; high guinea pig 5-HT1B/1D affinity (Ki: 0.24, 0.47 nM); 10x less for 5-HT1D (Ki: 5 nM).Formula:C27H36N4O2Purity:98%Color and Shape:SolidMolecular weight:448.6BFE-55
CAS:BFE-55 is derivative of befunolol (a beta-adrenergic partial agonist). BFE-55 interacts with only the high affinity sites in beta-adrenoceptorsFormula:C14H19NO3Purity:98%Color and Shape:SolidMolecular weight:249.31(Rac)-Upacicalcet
CAS:(Rac)-Upacicalcet, a racemate, is an IV calcimimetic targeting parathyroid receptors to lower PTH, possibly treating SHPT.Formula:C11H14ClN3O6SColor and Shape:SolidMolecular weight:351.76Thioperamide
CAS:histamine H3 and H4 antagonist/inverse agonistFormula:C15H24N4SPurity:98%Color and Shape:White SolidMolecular weight:292.44Ro 22-9194
CAS:Ro 22-9194, a class I antiarrhythmic, reduces upstroke velocity and shortens action potential in guinea-pig hearts at ≥10 μM.Formula:C19H27Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:384.35S(-)-8-Hydroxy-DPAT hydrobromide
CAS:S(-)-8-Hydroxy-DPAT hydrobromide is an agonist of 5-HT1A serotonin receptor.Formula:C16H26BrNOPurity:98%Color and Shape:SolidMolecular weight:328.29A2A receptor antagonist 3
CAS:A2A receptor antagonist 3 (Example 92) is an adenosine A2a receptor antagonist (Ki: 0.4 nM). receptor (Ki: 1467 nM).Formula:C26H26N6O2Color and Shape:SolidMolecular weight:454.52PD 118440
CAS:PD 118440 is a Dopamine antagonist. PD 118440 is an orally active dopamine (DA) agonists with pronounced central nervous system effects.Formula:C11H17N3SPurity:98%Color and Shape:SolidMolecular weight:223.34L-670,596
CAS:L-670,596 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist.Formula:C22H21F2NO4SPurity:98%Color and Shape:SolidMolecular weight:433.47SB 272183
CAS:SB 272183 is a highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drug.Formula:C29H28ClN5OPurity:98%Color and Shape:SolidMolecular weight:498.02Sch 24518
CAS:Sc h24518 is an antagonist of D1 receptor.Formula:C16H17BrClNOPurity:98%Color and Shape:SolidMolecular weight:354.67Iferanserin
CAS:Iferanserin (S-MPEC) is a selective antagonist of the 5-HT receptor (serotonin receptor) with an affinity for 5-HT2A receptors.Formula:C23H28N2OColor and Shape:SolidMolecular weight:348.48Tilisolol HCl
CAS:Tilisolol, a nonselective beta-blocker, dilates dog coronary arteries via ATP-sensitive K(+) channels.Formula:C17H25ClN2O3Purity:98%Color and Shape:SolidMolecular weight:340.85T 82
CAS:T 82 is an antagonist of 5-HT3 and inhibitor of acetylcholinesterase (AChE) and used for the treatment of Alzheimer's Disease.Formula:C56H62N6O8Purity:98%Color and Shape:SolidMolecular weight:947.146Lexipafant
CAS:Lexipafant is a platelet-activating factor (PAF) receptor antagonist.Formula:C23H30N4O4SColor and Shape:SolidMolecular weight:458.57MK-0249
CAS:MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).
Formula:C23H24F3N3O2Purity:99.90%Color and Shape:SolidMolecular weight:431.45Tulopafant
CAS:Tulopafant (RP 59227) is a potent platelet-activating factor (PAF) antagonist that increases capillary patency and prolongs allograft heart survival.Formula:C25H19N3O2SPurity:99.38%Color and Shape:SolidMolecular weight:425.5Todralazine
CAS:Todralazine is an anti-hypertensive agent and acts as a β2AR blocker. It also has an antioxidant and free radical scavenging activity.Formula:C11H12N4O2Purity:98%Color and Shape:SolidMolecular weight:232.24Lu AA41063
CAS:Lu AA41063 is a potent and selective antagonist of the hA2A receptor.Formula:C16H17F2N3O2SColor and Shape:SolidMolecular weight:353.39SKF-83566 hydrobromide
CAS:D1-like dopamine receptor antagonistFormula:C17H19BrClNOPurity:98%Color and Shape:SolidMolecular weight:368.7A1AR antagonist 6
CAS:A1AR antagonist 6 (compound 15) is a potent and selective antagonist of A1 adenosine receptor(A1AR) with a pKi of 7.13 and a pIC 50 of 6.38[1].Formula:C17H15N3O2Color and Shape:SolidMolecular weight:293.32SB 235375
CAS:SB 235375 is a potent and selective antagonist of neurokinin-3 receptor with a low central nervous system-penetrant.Formula:C27H24N2O4Purity:98%Color and Shape:SolidMolecular weight:440.49N-Salicyloyltryptamine
CAS:N-Salicyloyltryptamine (STP): a tryptamine with anticonvulsant, anti-inflammatory, analgesic effects; inhibits Na+, Ca2+, K+ channels (IC50 34.6 μM).Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32CAY10535
CAS:CAY10535 is a selective TPβ antagonist (IC50 = 99 nM for TPβ vs 1970 nM for TPα), weakly affects platelets (IC50 = 985 nM).Formula:C18H21N3O7SColor and Shape:SolidMolecular weight:423.44Isoproterenol-d7 HCl
CAS:Isoproterenol-d7: internal standard for GC/LC-MS. β1-/β2-AR agonist, not for β3. Lowers blood pressure, tackles bradydysrhythmias, asthma.Formula:C11H18ClNO3Color and Shape:SolidMolecular weight:254.76MS 245 oxalate
CAS:MS 245 oxalate is a 5-HT6 antagonist.Formula:C21H24N2O7SPurity:98%Color and Shape:SolidMolecular weight:448.49CCK-A receptor inhibitor 1
CAS:CCK-A receptor inhibitor 1 is a potent inhibitor of the cholecystokinin A (CCK-A) receptor (IC50: 340 nM).CCK-A receptor inhibitor 1 can be used for the studyFormula:C25H35NO6SPurity:99.47%Color and Shape:SolidMolecular weight:477.61Pamatolol
CAS:Pamatolol is a selective and potent beta-adrenoceptor antagonist that has not shown sympathomimetic activity in ex vivo experiments.Formula:C16H26N2O4Purity:>99.99%Color and Shape:SolidMolecular weight:310.39(4E)-SUN9221
CAS:(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity inFormula:C25H31FN4O3Purity:97.79%Color and Shape:SolidMolecular weight:454.54L-771688
CAS:L-771688 (SNAP 6383) is a novel potent and selective α1A-adrenoceptor antagonist with a Ki value of 0.43±0.02 nM.L-771688 KE is used for the treatment of benignFormula:C28H33F2N5O5Purity:94.15%Color and Shape:SolidMolecular weight:557.59PAF-AN-1
CAS:PAF-AN-1 is a novel potent platelet-activating factor receptor (PAF) antagonist involved in the study of anaphylactic death.Formula:C28H28N2O3Purity:98.06%Color and Shape:SolidMolecular weight:440.53TD-5471 hydrochloride
CAS:TD-5471 hydrochloride is a selective and potent long-acting human β2-adrenergic receptor agonist for the treatment of chronic obstructive pulmonary disease (Formula:C32H32ClN3O4Purity:99.57%Color and Shape:SolidMolecular weight:558.07Odapipam
CAS:Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).Formula:C19H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:329.82Napitane
CAS:napitane (A 75200) is a novel catecholamine uptake inhibitor with inhibitory effects on α-adrenergic receptors and potential antidepressant activity for the
Formula:C22H25NO2Purity:99.77% - 99.89%Color and Shape:SolidMolecular weight:335.44LY 225910
CAS:LY 225910 is a CCK2 receptor antagonist.Formula:C27H24BrN3O2Purity:98%Color and Shape:SolidMolecular weight:502.4Methdilazine Hydrochloride
CAS:Methdilazine Hydrochloride (Bristaline) is a histamine H1 receptor antagonist for dermatologic conditions and relief of itching by allergies or rhinitis.Formula:C18H21ClN2SColor and Shape:Light-Tan Crystalline Powder 4 8-6 (Ntp 1992)Molecular weight:332.89A68930
CAS:A 68930 is a dopamine D-1 receptor antagonist. A 68930 inhibits NLRP3 inflammasome activity.Formula:C16H17NO3Color and Shape:SolidMolecular weight:271.31DH97
CAS:MT2 melatonin receptor antagonistFormula:C22H26N2OPurity:98%Color and Shape:SolidMolecular weight:334.45RP73870
CAS:RP73870 is a gastrin/cholecystokinin-B receptor antagonist and H2 receptor antagonist with potent anti-ulcer activity.Formula:C27H30N4O7SPurity:98%Color and Shape:SolidMolecular weight:554.61
