GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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MAT2A-IN-1
CAS:MAT2A-IN-1 suppresses MAT2A, key for MTAP-deficient cancer cell growth; studied for gastric, colon, liver, pancreatic cancers.Formula:C29H28F2N6O4Color and Shape:SolidMolecular weight:562.57MRS2298
CAS:MRS2298, a potent antagonists of the P2Y 1 receptor, has antiaggregatory activity in human platelets.Formula:C10H16ClN5O8P2Purity:98%Color and Shape:SolidMolecular weight:431.66PF-4522654
CAS:PF-4522654 is a potent and selective 5-HT2C receptor agonist.Formula:C16H18F2N4Color and Shape:SolidMolecular weight:304.34BRL 44408 Maleate Salt
CAS:BRL 44408 Maleate is an α2A-adrenoceptor antagonist with antidepressant and analgesic activity.Formula:C17H21N3O4Purity:98.71%Color and Shape:SolidMolecular weight:331.37Cgp 52608
CAS:CGP 52608 is a selective ligand for RAR-associated orphan receptor alpha.Formula:C8H12N4OS2Color and Shape:SolidMolecular weight:244.34Ro 60-0175 fumarate
CAS:5-HT2 receptor agonistFormula:C15H16ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:342.75Carcinine
CAS:Carcinine ditrifluoroacetate is a H3 receptor antagonist.Formula:C8H14N4OPurity:98%Color and Shape:SolidMolecular weight:182.22PF-06412154 HCl
CAS:PF-06412154 HCl is a glucagon receptor antagonist.Formula:C24H28ClN3O3Color and Shape:SolidMolecular weight:441.96Thromboxane B2
CAS:Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces platelet aggregation and arterial contraction.Formula:C20H34O6Color and Shape:SolidMolecular weight:370.48L-Alprenolol
CAS:L-Alprenolol is a non-selective beta-blocker and a 5-HT1A and 5-HT1B receptor antagonist.Formula:C15H23NO2Purity:98%Color and Shape:SolidMolecular weight:249.35MRS1186
CAS:MRS1186 is an effective and selective antagonist of the human Adenosine A3 receptor (Ki: 7.66 nM).Formula:C16H12ClN5O2Purity:98%Color and Shape:SolidMolecular weight:341.75PF-4479745
CAS:PF-4479745 ia a potent and selective agonist of 5-HT2C receptor.Formula:C17H22N4Purity:98%Color and Shape:SolidMolecular weight:282.38Remoxipride
CAS:Remoxipride is an antipsychotic agent. Remoxipride is specific for dopamine D2 receptors.Formula:C16H23BrN2O3Purity:98%Color and Shape:SolidMolecular weight:371.27(RS)-Butyryltimolol
CAS:(RS)-Butyryltimolol, a racemic prodrug of Timolol, enhances its corneal absorption and acts as a β-adrenergic blocker.Formula:C17H30N4O4SPurity:98%Color and Shape:SolidMolecular weight:386.51Monatepil maleate
CAS:Monatepil maleate (AJ-2615 maleate) is a Ca2+-channel and α1-adrenergic receptor antagonist, and ACAT inhibitor with antihypertensive activity.Formula:C32H34FN3O5SPurity:97.90%Color and Shape:SolidMolecular weight:591.69Efpeglenatide
CAS:Efpeglenatide is a long-acting GLP-1 receptor agonist that improves insulin sensitivity, lowers blood glucose, delays weight gain, and supports metabolic disease research.Purity:100% - 100%Color and Shape:SolidBenzatropine
CAS:Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.Formula:C21H25NOPurity:98%Color and Shape:SolidMolecular weight:307.43γ-Linolenic acid ethyl ester
CAS:γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B 4 receptor 4 (LTB 4 ) antagonist which has a potential anti-inflammatory effect[1].Formula:C20H34O2Color and Shape:SolidMolecular weight:306.48Alaproclate (hydrochloride)
CAS:Alaproclate, an SSRI, enhances serotonin and SIRT1, hinders NMDA and K+ currents in neurons, and shows antidepressant-like effects in rats.Formula:C13H19Cl2NO2Color and Shape:SolidMolecular weight:292.2NR2F1 agonist 1
CAS:NR2F1 agonist 1 activates cancer cell dormancy, suppresses growth in HNSCC, and inhibits tumor growth in mice.Formula:C28H30N4OSColor and Shape:SolidMolecular weight:470.63Levemopamil HCl
CAS:Levemopamil HCl is used as a calcium channel blocker.Formula:C23H31ClN2Purity:98%Color and Shape:SolidMolecular weight:370.96SB 206553 hydrochloride
CAS:SB 206553 hydrochloride is a 5-HT2C inverse agonist and a 5-HT2C/5-HT2B receptor antagonist with anxiolytic activity, useful for studying neurological disordersFormula:C17H17ClN4OPurity:99.56%Color and Shape:SolidMolecular weight:328.8NVS-CRF38
CAS:NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1).Formula:C19H21N5O2Purity:98%Color and Shape:SolidMolecular weight:351.4AR-A 2
CAS:AR-A 2, a selective 5-HT1B antagonist; high guinea pig 5-HT1B/1D affinity (Ki: 0.24, 0.47 nM); 10x less for 5-HT1D (Ki: 5 nM).Formula:C27H36N4O2Purity:98%Color and Shape:SolidMolecular weight:448.6Amosulalol, (+)-
CAS:Amosulalol, (+)-, is an adrenergic agent.Formula:C18H24N2O5SColor and Shape:SolidMolecular weight:380.46BFE-55
CAS:BFE-55 is derivative of befunolol (a beta-adrenergic partial agonist). BFE-55 interacts with only the high affinity sites in beta-adrenoceptorsFormula:C14H19NO3Purity:98%Color and Shape:SolidMolecular weight:249.31(Rac)-Upacicalcet
CAS:(Rac)-Upacicalcet, a racemate, is an IV calcimimetic targeting parathyroid receptors to lower PTH, possibly treating SHPT.Formula:C11H14ClN3O6SColor and Shape:SolidMolecular weight:351.76CP-122721
CAS:CP-122721: NK1 receptor blocker, has antidepressant, anti-anxiety, antiemetic effects, and selectively inhibits substance P receptors.Formula:C20H23F3N2O2Color and Shape:SolidMolecular weight:380.4Thioperamide
CAS:histamine H3 and H4 antagonist/inverse agonistFormula:C15H24N4SPurity:98%Color and Shape:White SolidMolecular weight:292.44Z-335 sodium
CAS:Z-335 Salt, a thromboxane A2 receptor antagonist, is used potentially for the treatment of arterial occlusive disease.Formula:C18H18ClNNaO4SColor and Shape:SolidMolecular weight:402.84Ro 22-9194
CAS:Ro 22-9194, a class I antiarrhythmic, reduces upstroke velocity and shortens action potential in guinea-pig hearts at ≥10 μM.Formula:C19H27Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:384.35A2A receptor antagonist 3
CAS:A2A receptor antagonist 3 (Example 92) is an adenosine A2a receptor antagonist (Ki: 0.4 nM). receptor (Ki: 1467 nM).Formula:C26H26N6O2Color and Shape:SolidMolecular weight:454.52YM-430
CAS:YM-430: β1 blocker & Ca²⁺ channel antagonist; antianginal & antihypertensive; IC50: 59.2 nM (rhythmic contractions), 36.6 mg/kg in rats (ST depression).Formula:C29H35N3O8Purity:98%Color and Shape:SolidMolecular weight:553.6N,N-Dimethylsphingosine
CAS:N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.Formula:C20H41NO2Purity:98%Color and Shape:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderMolecular weight:327.55VPC12249
CAS:VPC12249, a lysophosphatidic acid receptor type 1 (LPA1) antagonist, plays a functional role in osteoclast differentiation and bone resorption activity.Formula:C34H52NO6PColor and Shape:SolidMolecular weight:601.75Pirepemat fumarate
CAS:Pirepemat fumarate (IRL752), aids Parkinson's research, boosts cognition and cortical catecholamine transmission.Formula:C15H17F2NO5Color and Shape:SolidMolecular weight:329.3L-670,596
CAS:L-670,596 is a thromboxane A2/prostaglandin endoperoxide receptor antagonist.Formula:C22H21F2NO4SPurity:98%Color and Shape:SolidMolecular weight:433.47T 82
CAS:T 82 is an antagonist of 5-HT3 and inhibitor of acetylcholinesterase (AChE) and used for the treatment of Alzheimer's Disease.Formula:C56H62N6O8Purity:98%Color and Shape:SolidMolecular weight:947.146Medroxalol hydrochloride
CAS:Medroxalol hydrochloride is an antihypertensive agent that possesses both alpha and beta-adrenergic antagonistic properties.Formula:C20H25ClN2O5Color and Shape:SolidMolecular weight:408.88Amosulalol, (-)-
CAS:Amosulalol, (-)-, is an adrenergic agent.Formula:C18H24N2O5SColor and Shape:SolidMolecular weight:380.46NGD 98-2
CAS:NGD 98-2 is a new generation, topology 2 selective orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.Formula:C19H24F3N3O3Color and Shape:SolidMolecular weight:399.41Trimazosin hydrochloride
CAS:Trimazosin hydrochloride is used in the treatment of hypertensive patients failing to respond to thiazides.Formula:C20H32ClN5O7Color and Shape:SolidMolecular weight:489.95Lexipafant
CAS:Lexipafant is a platelet-activating factor (PAF) receptor antagonist.Formula:C23H30N4O4SColor and Shape:SolidMolecular weight:458.57mCPBG
CAS:mCPBG is a potent high affinity agonist of 5-HT3 receptor.Formula:C8H10ClN5Color and Shape:SolidMolecular weight:211.65ChemR23-IN-2
CAS:ChemR23-IN-2 is a potent, orally active inhibitor of ChemR23 (IC50: 3.2 nM).Formula:C29H26N4O5Color and Shape:SolidMolecular weight:510.54RX821002
CAS:RX821002: potent α2-adrenoceptor antagonist, selective for α2D (pKd 9.7) over α2A (pKd 8.2), low affinity for imidazoline.Formula:C12H14N2O3Purity:98%Color and Shape:SolidMolecular weight:234.25Todralazine
CAS:Todralazine is an anti-hypertensive agent and acts as a β2AR blocker. It also has an antioxidant and free radical scavenging activity.Formula:C11H12N4O2Purity:98%Color and Shape:SolidMolecular weight:232.24Etrasimod arginine
CAS:Etrasimod arginine is used in the Treatment of Autoimmune and Inflammatory Diseases.Formula:C32H40F3N5O5Color and Shape:SolidMolecular weight:631.69EA-230
CAS:Ea-230 is an immunomodulator that may be used in the treatment of renal failure.Formula:C15H27N5O6Color and Shape:SolidMolecular weight:373.4Lu AA41063
CAS:Lu AA41063 is a potent and selective antagonist of the hA2A receptor.Formula:C16H17F2N3O2SColor and Shape:SolidMolecular weight:353.39
