GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5964 products of "GPCR/G-Protein"
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Spizofurone
CAS:Spizofurone (Espizofurona) has anti-ulcer activity, protective effect on the gastric mucosa of rats and can increase alkaline secretion.Formula:C12H10O3Purity:>99.99%Color and Shape:SolidMolecular weight:202.21TC LPA5 4
CAS:TC LPA5 4 is a LPA5 receptor antagonist.Formula:C23H23ClN2O3Purity:99.93%Color and Shape:SolidMolecular weight:410.89Ref: TM-T23438
1mg49.00€5mg98.00€10mg157.00€25mg324.00€50mg485.00€100mg713.00€200mg982.00€1mL*10mM (DMSO)107.00€Ronacaleret HCl
CAS:Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.Formula:C25H32ClF2NO4Purity:99.97%Color and Shape:SolidMolecular weight:483.98SC 19220
CAS:SC 19220 is a prostaglandin E2 receptor EP1 antagonist that inhibits RANKL-induced osteoclastogenesis.Formula:C16H14ClN3O3Purity:98%Color and Shape:SolidMolecular weight:331.75Ref: TM-T23330
1mg43.00€5mg93.00€10mg152.00€25mg298.00€50mg440.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)92.00€CL 316243
CAS:CL316243 is a highly potent selective agonist of β3-adrenoceptor.Cost-effective and quality-assured.Formula:C20H18ClNNa2O7Purity:98.00% - 99.68%Color and Shape:SolidMolecular weight:465.79FPL 55712
CAS:FPL 55712 is a leukotriene receptor and SRS-A antagonist that inhibits bronchoconstriction and can be used in studies of asthma and coronary artery thrombosis.Formula:C27H30O9Purity:98.15% - 99.8%Color and Shape:SolidMolecular weight:498.52R 59-022 hydrochloride
CAS:R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formula:C27H27ClFN3OSPurity:97.7%Color and Shape:SolidMolecular weight:496.04GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Formula:C23H27N3O2Purity:99.75%Color and Shape:SolidMolecular weight:377.48Soquinolol
CAS:Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a longFormula:C17H26N2O3Purity:97.48% - 98.63%Color and Shape:SolidMolecular weight:306.4DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purity:99.91% - 99.99%Color and Shape:SolidMolecular weight:443.37Antihistamine-1
CAS:Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。Formula:C23H24FN5Purity:99.69%Color and Shape:SolidMolecular weight:389.47L 651896
CAS:L 651896 is an inhibitor of 5-lipoxygenase.Formula:C18H18O3Purity:96.06% - 99.85%Color and Shape:SolidMolecular weight:282.33RG 7152
CAS:RG 7152 is a leukotriene D4 antagonist with anti-asthmatic properties and can be used in the study of asthma.Formula:C20H19N5O2Purity:98.45%Color and Shape:SolidMolecular weight:361.4Isbogrel
CAS:Isbogrel (CV4151) is a TXA2 synthase inhibitor for researching arrhythmias, ischemic attacks, and thrombosis.Formula:C18H19NO2Purity:99.58%Color and Shape:SolidMolecular weight:281.35Fipamezole
CAS:Fipamezole is a potent alpha2 adrenergic receptor antagonist that may be useful for studying autonomic dysfunction in Parkinson's disease.Formula:C14H15FN2Purity:99.32% - 99.97%Color and Shape:SolidMolecular weight:230.28Edonentan
CAS:Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.Formula:C28H32N4O5SPurity:98.07% - 99.6%Color and Shape:SolidMolecular weight:536.64Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurity:98.77% - 99.67%Color and Shape:SolidMolecular weight:233.35Elinogrel
CAS:Elinogrel (PRT060128) is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 nM and exhibits potent antiplatelet effects.Formula:C20H15ClFN5O5S2Purity:98.78%Color and Shape:SolidMolecular weight:523.95Ref: TM-T11177
1mg37.00€5mg70.00€10mg97.00€25mg170.00€50mg235.00€100mg329.00€200mg472.00€1mL*10mM (DMSO)81.00€Remoxipride hydrochloride
CAS:Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-Formula:C16H24BrClN2O3Purity:99.88%Color and Shape:SolidMolecular weight:407.73SDZ-62-434
CAS:SDZ-62-434 is a platelet-activating factor inhibitor with antitumor activity and may be used in the study of leukemia.Formula:C23H27Cl2N3Purity:98.38%Color and Shape:SolidMolecular weight:416.39RO3244794
CAS:RO3244794 is a selective prostacyclin (IP) receptor antagonist that can be used to study liver injury.Formula:C25H19F2NO5Purity:99.36%Color and Shape:SolidMolecular weight:451.42Pirodomast
CAS:Pirodomast is a thromboxane A (TXA2) synthase inhibitor.Formula:C18H17N3O2Purity:99.14%Color and Shape:SolidMolecular weight:307.35Medifoxamine
CAS:Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.MedifoxamineFormula:C16H19NO2Purity:98.88%Color and Shape:SolidMolecular weight:257.33Ref: TM-T24444
1mg94.00€5mg222.00€10mg334.00€25mg602.00€50mg845.00€100mg1,099.00€1mL*10mM (DMSO)245.00€(Z)-Thiothixene
CAS:(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.
Formula:C23H29N3O2S2Purity:99.21%Color and Shape:Yellow To Yellow With A Tan Cast PowderMolecular weight:443.63Egis-11150
CAS:Egis-11150 is a potent inhibitor of adrenergic alpha1, alpha2c, 5-HT2a, 5HT7 receptors.Formula:C19H21ClFN5O2Purity:97.49% - >99.99%Color and Shape:SolidMolecular weight:405.85Ticalopride
CAS:Ticalopride: 5-HT3 agonist for digestive, orofacial, ENT disorders, and bulimia, GERD, IBS research.Formula:C14H20ClN3O3Purity:99.51%Color and Shape:SolidMolecular weight:313.78APNEA
CAS:APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) is a non-selective agonist of adenosine A3 receptor.Formula:C18H22N6O4Purity:99.88%Color and Shape:SolidMolecular weight:386.41Cianopramine
CAS:Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.Formula:C20H23N3Purity:99.92% - 99.92%Color and Shape:SolidMolecular weight:305.42ASP-4058
CAS:ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.Formula:C19H12F6N4O2Purity:99.92% - 99.96%Color and Shape:SolidMolecular weight:442.31Lensiprazine
CAS:Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder andFormula:C24H27FN4O2Purity:97.86%Color and Shape:SolidMolecular weight:422.5PD 168568 dihydrochloride
CAS:PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).Formula:C22H29Cl2N3OPurity:99.71%Color and Shape:SolidMolecular weight:422.39Ref: TM-T12383
5mg46.00€10mg55.00€25mg111.00€50mg166.00€100mg235.00€200mg329.00€1mL*10mM (DMSO)57.00€BMS 182874
CAS:BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.Formula:C17H19N3O3SPurity:99.73%Color and Shape:SolidMolecular weight:345.425-HT2 antagonist 1
CAS:5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.Formula:C22H29FN4O2Purity:99.76%Color and Shape:SolidMolecular weight:400.49Ref: TM-T12597
1mg642.00€5mg1,288.00€10mg1,738.00€25mg2,583.00€50mg3,484.00€100mg4,708.00€1mL*10mM (DMSO)1,521.00€Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Formula:C28H37BrN4O3Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:557.533Proxyfan
CAS:Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.Formula:C13H16N2OPurity:99.68%Color and Shape:SolidMolecular weight:216.28Camonagrel
CAS:Camonagrel is a compound that has inhibitory effects on Prostaglandin E2.Formula:C15H16N2O3Purity:98.71% - 99.25%Color and Shape:SolidMolecular weight:272.3CB2R PAM
CAS:CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.Formula:C21H24BrFN2O2Purity:99.09%Color and Shape:SolidMolecular weight:435.33E6801
CAS:E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.Formula:C17H18ClN5O2S2Purity:96.32% - 97.24%Color and Shape:SolidMolecular weight:423.94JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Formula:C22H20ClN5OPurity:99.82%Color and Shape:SolidMolecular weight:405.88Cilansetron
CAS:Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.Formula:C20H21N3OPurity:99.82% - 99.98%Color and Shape:SolidMolecular weight:319.4Upacicalcet
CAS:Upacicalcet (AJT-240) is a calcium mimetic for SHPT in dialysis, reducing PTH by targeting parathyroid receptors.Formula:C11H14ClN3O6SPurity:99.88%Color and Shape:SolidMolecular weight:351.76Ex26
CAS:Ex26 (S1P1-IN-Ex26) is an S1P1 antagonist used in experimental autoimmune encephalomyelitis, atherosclerosis, and gastric cancer.Formula:C28H28ClFN2O3Purity:99.62%Color and Shape:SolidMolecular weight:494.99Sonedenoson
CAS:Sonedenoson (MRE0094) is an adenosine A(2A) receptor agonist and potential inhibitor potentially targeting SARS-CoV-2 coronavirus 2;-O-ribose methyltransferase.Formula:C18H20ClN5O5Purity:99.79%Color and Shape:SolidMolecular weight:421.84Pirmagrel
CAS:pirmagrel is a potent thromboxane synthase inhibitor.Formula:C13H16N2O2Purity:98.02%Color and Shape:SolidMolecular weight:232.28Clemastine
CAS:Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.Formula:C21H26ClNOPurity:99.21%Color and Shape:SolidMolecular weight:343.89Linetastine
CAS:Linetastine (TMK-688) inhibits 5-LOX, blocks leukotrienes, counters histamine; researched for asthma, atherosclerosis, ulcers.Formula:C35H40N2O6Purity:99.99%Color and Shape:SolidMolecular weight:584.7Sarizotan HCl
CAS:Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.Formula:C22H22ClFN2OPurity:96%Color and Shape:SolidMolecular weight:384.87MLS1547
CAS:MLS1547 is a potent D2 receptor G protein-biased agonist (Ki=1.2 μM, EC50=0.37 μM in Ca2+ assay).Formula:C19H19ClN4OPurity:99.64%Color and Shape:SolidMolecular weight:354.83Enerisant hydrochloride
CAS:Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteinsFormula:C22H31ClN4O3Purity:99.95%Color and Shape:SolidMolecular weight:434.96(R)-ZINC-3573
CAS:ZINC-3573: Potent, selective MRGPRX2 activator; triggers mast cell degranulation and calcium release.
Formula:C18H21N5Purity:99.75%Color and Shape:SolidMolecular weight:307.39
