CymitQuimica logo
GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 19 more subcategories

Found 5938 products of "GPCR/G-Protein"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • 16(R)-Iloprost
    Targetmol
    + Info

    16(R)-Iloprost

    CAS:
    Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).
    Formula:C22H32O4
    Color and Shape:Solid
    Molecular weight:360.49

    Ref: TM-T36211

  • F 14679
    Targetmol
    + Info

    F 14679

    CAS:
    <p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>
    Formula:C21H25ClF2N4O
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:422.9

    Ref: TM-T62269

  • BRD50837
    Targetmol
    + Info

    BRD50837

    CAS:
    BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
    Formula:C26H32ClN3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:550.07

    Ref: TM-T26899

  • CymitQuimica logo
    Targetmol
    + Info

    SB 258741 hydrochloride

    SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].
    Formula:C19H31ClN2O2S
    Color and Shape:Solid
    Molecular weight:386.98

    Ref: TM-T61724

  • BRL-37344
    Targetmol
    + Info

    BRL-37344

    CAS:
    <p>BRL-37344 is a selective β3-adrenergic receptor agonist. It significantly reduces the body weight of obese mice.</p>
    Formula:C19H22ClNO4
    Color and Shape:Solid
    Molecular weight:363.84

    Ref: TM-T88348

  • SGLT1/2-IN-1
    Targetmol
    + Info

    SGLT1/2-IN-1

    CAS:
    SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.
    Formula:C25H28O8
    Color and Shape:Solid
    Molecular weight:456.48

    Ref: TM-T62830

  • Udifitimod
    Targetmol
    + Info

    Udifitimod

    CAS:
    Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.
    Formula:C25H33NO2
    Color and Shape:Solid
    Molecular weight:379.54

    Ref: TM-T73092

  • MRS2279 diammonium
    Targetmol
    + Info

    MRS2279 diammonium

    CAS:
    MRS2279 diammonium, a P2Y1 antagonist with K i 2.5 nM, IC 50 51.6 nM, blocks ADP-induced platelet aggregation, pK b 8.05.
    Formula:C13H24ClN7O8P2
    Color and Shape:Solid
    Molecular weight:503.77

    Ref: TM-T72514

  • 5-HT7R antagonist 3
    Targetmol
    + Info

    5-HT7R antagonist 3

    CAS:
    Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.
    Formula:C30H33FN4O3
    Color and Shape:Solid
    Molecular weight:516.61

    Ref: TM-T201849

  • ASP-2205
    Targetmol
    + Info

    ASP-2205

    CAS:
    ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.
    Formula:C19H28N2O
    Color and Shape:Solid
    Molecular weight:300.44

    Ref: TM-T201450

  • Etoperidone
    Targetmol
    + Info

    Etoperidone

    CAS:
    Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).
    Formula:C19H28ClN5O
    Color and Shape:Solid
    Molecular weight:377.91

    Ref: TM-T201838

  • UMB24
    Targetmol
    + Info

    UMB24

    CAS:
    UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of 170 nM for the σ2 receptor and 322 nM for the σ1 receptor. This compound mitigates cocaine-induced convulsions and hyperactivity without causing mortality.
    Formula:C17H21N3
    Color and Shape:Solid
    Molecular weight:267.37

    Ref: TM-T201855

  • FDU-PB-22
    Targetmol
    + Info

    FDU-PB-22

    CAS:
    FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.
    Formula:C26H18FNO2
    Color and Shape:Solid
    Molecular weight:395.43

    Ref: TM-T201691

  • Nolpitantium besilate
    Targetmol
    + Info

    Nolpitantium besilate

    CAS:
    Nolpitantium besilate is a neurokinin-1 receptor antagonist.
    Formula:C43H50Cl2N2O5S
    Color and Shape:Solid
    Molecular weight:777.84

    Ref: TM-T70455

  • O-1269
    Targetmol
    + Info

    O-1269

    CAS:
    O-1269 acts as a partial agonist for the cannabinoid receptor 1 (CB1R), with a binding affinity (Ki) of 32 nM. Additionally, it exhibits analgesic properties.
    Formula:C22H22Cl3N3O
    Color and Shape:Solid
    Molecular weight:450.79

    Ref: TM-T201557

  • RBM10-8
    Targetmol
    + Info

    RBM10-8

    CAS:
    RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.
    Formula:C17H36NO5P
    Color and Shape:Solid
    Molecular weight:365.45

    Ref: TM-T61406

  • AB-FUBINACA 3-fluorobenzyl isomer
    Targetmol
    + Info

    AB-FUBINACA 3-fluorobenzyl isomer

    CAS:
    AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.
    Formula:C20H21FN4O2
    Color and Shape:Solid
    Molecular weight:368.41

    Ref: TM-T201486

  • Dinoxyline
    Targetmol
    + Info

    Dinoxyline

    CAS:
    Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.
    Formula:C15H13NO3
    Color and Shape:Solid
    Molecular weight:255.27

    Ref: TM-T201856

  • CymitQuimica logo
    Targetmol
    + Info

    25C-NBF hydrochloride

    CAS:
    25C-NBF hydrochloride is an agonist of 5-HT receptors, specifically activating 5-HT2A and 5-HT2C receptors, with an EC50 of approximately 0.3 μM.
    Formula:C17H20Cl2FNO2
    Molecular weight:360.251

    Ref: TM-T204576

  • Elzasonan hydrochloride
    Targetmol
    + Info

    Elzasonan hydrochloride

    CAS:
    Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.
    Formula:C22H24Cl3N3OS
    Color and Shape:Solid
    Molecular weight:484.87

    Ref: TM-T201763