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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5938 products of "GPCR/G-Protein"

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  • L 156903

    CAS:
    L 156903 is a bioactive chemical. It also inhibits the binding of neurotensin to brain tissue.
    Formula:C35H41N7O5S
    Color and Shape:Solid
    Molecular weight:671.81
  • 5-HT2A receptor agonist-7

    CAS:
    5-HT2A receptor agonist-7 (517) functions as a modulator of the 5-HT2A receptor, with an EC50 value of less than 100 nM.
    Formula:C12H11F2N3
    Molecular weight:235.233
  • SB 224289

    CAS:
    SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.
    Formula:C32H32N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.62
  • Zafirlukast metabolite M1

    CAS:
    <p>Zafirlukast metabolite M1 (compound 15) is an inhibitor used in the treatment of asthma and other allergic pulmonary conditions, effectively antagonizing leukotriene activity.</p>
    Formula:C25H25N3O4S
    Color and Shape:Solid
    Molecular weight:463.549
  • Ac-Atovaquone

    CAS:
    Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.
    Formula:C24H21ClO4
    Color and Shape:Solid
    Molecular weight:408.87
  • Leukotriene F4

    CAS:
    LTF4, made in vitro from LTE4 with enzymes, contracts vascular muscle weakly; potency is LTD4 > LTC4 > LTE4 >> LTF4.
    Formula:C28H44N2O8S
    Color and Shape:Solid
    Molecular weight:568.72
  • Aplaviroc hydrochloride

    CAS:
    Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.
    Formula:C33H44ClN3O6
    Color and Shape:Solid
    Molecular weight:614.17
  • NPRA agonist-11

    CAS:
    NPRA agonist-11 (Example 161) is an NPRA (NPR1) agonist with AC50 values of 1.681 μM and 0.989 μM for human and monkey, respectively. It is applicable in research on cardiovascular and other diseases.
    Formula:C37H52FN7O2
    Color and Shape:Solid
    Molecular weight:645.85
  • GPBAR1-IN-3

    CAS:
    GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].
    Formula:C21H23NO2
    Color and Shape:Solid
    Molecular weight:321.41
  • Neladenoson

    CAS:
    Neladenoson is an effective and selective agonist of the Adenosine A1 Receptor (A1R). EGFR-IN-162 shows potential for research in heart failure.
    Formula:C29H24ClN5O2S2
    Color and Shape:Solid
    Molecular weight:574.12
  • Alixorexton

    CAS:
    <p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>
    Formula:C21H30N2O5S
    Color and Shape:Solid
    Molecular weight:422.538
  • 8 Hydroxy PIPAT oxalate

    CAS:
    8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.
    Formula:C18H24INO5
    Color and Shape:Solid
    Molecular weight:461.29
  • PF-07258669

    CAS:
    PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
    Formula:C25H27FN6O2
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:462.52
  • BQ-788

    CAS:
    BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.
    Formula:C34H51N5O7
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:641.8
  • AZD-5672

    CAS:
    AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.
    Formula:C32H38F2N2O5S2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:632.78
  • SB-423562

    CAS:
    SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.
    Formula:C26H32N2O4
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:436.54
  • Treprostinil diethanolamine

    CAS:
    <p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>
    Formula:C27H45NO7
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:495.65
  • Vofopitant dihydrochloride

    CAS:
    Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.
    Formula:C21H25Cl2F3N6O
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:505.36
  • Vofopitant

    CAS:
    Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).
    Formula:C21H23F3N6O
    Purity:97.86%
    Color and Shape:Solid
    Molecular weight:432.44
  • SB-224289 hydrochloride

    CAS:
    SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.
    Formula:C32H33ClN4O3
    Purity:98.99% - 99.96%
    Color and Shape:Solid
    Molecular weight:557.08