GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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Dolcanatide
CAS:Dolcanatide: oral GC-C agonist with laxative, pain-relief, and anti-inflammatory properties for IBD research.Formula:C65H104N18O26S4Color and Shape:SolidMolecular weight:1681.89P4pal10 TFA
P4pal10 TFA, the TFA salt form of P4pal10, serves as an antagonist of the protease-activated receptor 4 (PAR4). This compound inhibits platelet aggregation and thrombin generation induced by tissue factor (TF), exhibiting anticoagulant and antithrombotic activities. Additionally, P4pal10 TFA alleviates carrageenan-induced edema and neutrophil infiltration, and ameliorates damage in rat myocardial ischemia/reperfusion (I/R) models.Color and Shape:Odour SolidLys-[Des-Arg9]Bradykinin TFA
CAS:Lys-[Des-Arg9]Bradykinin TFA: natural kinin, selective B1 agonist; Ki: 0.12 nM (human), 1.7 nM (mouse), 0.23 nM (rabbit); weak on B2 receptors.Formula:C54H75F6N13O15Color and Shape:SolidMolecular weight:1260.24[8-L-arginine] deaminovasopressin
CAS:[8-L-arginine] deaminovasopressin (dAVP) is a vasopressin analog [1] .Formula:C46H64N14O13S2Color and Shape:SolidMolecular weight:1085.22YFLLRNP
CAS:YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.Formula:C45H67N11O10Color and Shape:SolidMolecular weight:922.08Methionyl-Lysyl-Bradykinin
CAS:Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin analogue, is a kinin [1] [2] .Formula:C61H94N18O13SColor and Shape:SolidMolecular weight:1319.58TRAP-6 amide
CAS:TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.Formula:C34H57N11O8Color and Shape:SolidMolecular weight:747.899PACAP (6-38), human, ovine, rat acetate
PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptorFormula:C184H303N55O48SPurity:99.84%Color and Shape:SoildMolecular weight:4085.84Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Formula:C152H243N47O44S4Purity:98%Color and Shape:SolidMolecular weight:3561.1EP3 antagonist 4
CAS:EP3 antagonist 4: hEP inhibitor, Ki = 2 nM, low clearance, high oral AUC, good bioavailability in rats, potential for diabetes research.Formula:C22H20Cl3FN4O3S2Purity:98%Color and Shape:SoildMolecular weight:577.91Kisspeptin-54(human)
CAS:Endogenous ligand for KISS1 receptor; Ki values: rat 1.80 nM, human 1.45 nM. Inhibits tumor spread, stimulates gonadotropin release.Formula:C258H401N79O78Purity:98%Color and Shape:SolidMolecular weight:5857.49PA-8
CAS:PA-8: Selective PAC1 antagonist, orally active, blocks CREB phosphorylation & cAMP increase (IC50=2nM), reduces pain & aversive response in vivo.Formula:C17H18N4O4Purity:97.54%Color and Shape:SolidMolecular weight:342.35Ivabradine-d3 hydrochloride
CAS:Ivabradine HCl: novel If blocker, IC50 2.9 μM, slows heart rate; D3 version is deuterium labeled.Formula:C27H37ClN2O5Purity:98%Color and Shape:SolidMolecular weight:508.07Sigma-1 receptor antagonist 4
Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine's analgesic effects and reverses morphine-inducedFormula:C22H26N2OColor and Shape:SolidMolecular weight:334.45NXT-10796
NXT-10796 is an orally active, intestinally restricted agonist of the EP4 receptor [1].Formula:C23H31N3O6Purity:98%Color and Shape:SolidMolecular weight:445.514-Methylhistamine
CAS:4-Methylhistamine serves as a potent agonist for the histamine 4 receptor (H4R), holding promise for research into immune-related diseases, including cancer andFormula:C6H11N3Purity:98%Color and Shape:SolidMolecular weight:125.17AZP-531
CAS:Azp-531 is a disacylated ghrelin used to improve blood sugar control and weight loss.Formula:C40H63N15O13Purity:98%Color and Shape:SolidMolecular weight:962.02Conopeptide rho-TIA
CAS:Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human α1B-Adrenergic Receptor and as a competitiveFormula:C105H160N36O21S4Purity:98%Color and Shape:SolidMolecular weight:2390.88Atrial natriuretic peptide (3-28) (human)
CAS:Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation ofFormula:C118H187N43O36S3Purity:98%Color and Shape:SolidMolecular weight:2880.21Guanylate cyclase-IN-1
CAS:Guanylate cyclase-IN-1 (Example 46) is a specific inhibitor of guanylate cyclase, employed in research related to cardiovascular diseases.Formula:C20H17FN8OColor and Shape:SolidMolecular weight:404.409
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