GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5964 products of "GPCR/G-Protein"
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SBI-810
CAS:SBI-810 is a functional selective β-arrestin-biased allosteric modulator of the neurotensin receptor 1 (NTSR1). In the presence of the endogenous ligand neurotensin (NT), SBI-810 regulates NTSR1 signaling through a G protein-specific mechanism. It fully antagonizes NT-induced Gq activation and partially antagonizes NT-induced Gi1 activation, allowing NTSR1 to activate GoA and G12.Formula:C27H34N4O2Color and Shape:SolidMolecular weight:446.59Maceneolignan H
CAS:Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.Formula:C24H30O7Color and Shape:SolidMolecular weight:430.496-Fluoro-N,N-diethyltryptamine
CAS:6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formula:C14H19FN2Color and Shape:SolidMolecular weight:234.31(Des-Bromo)-Neuropeptide B (1-23) (human)
CAS:'(Des-Bromo)-Neuropeptide B (1-23) (human)' is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM forFormula:C107H162N30O30Color and Shape:SolidMolecular weight:2348.61BQ-123 TFA
BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.Formula:C33H43F3N6O9Color and Shape:SolidMolecular weight:724.72MRS 4062 triethylammonium salt
CAS:MRS 4062 triethylammonium salt is a selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively).Formula:C42H86N7O15P3Color and Shape:SolidMolecular weight:1022.105EP4-IN-1
CAS:EP4-IN-1: Potent EP4 receptor inhibitor with anti-tumor, anti-inflammatory, and analgesic properties.Formula:C27H24N2O4Purity:99.94%Color and Shape:SoildMolecular weight:440.495-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formula:C22H22Cl2FN3O3SColor and Shape:SolidMolecular weight:498.4B7-33
CAS:B7-33 is a single-chain relaxin analog and a selective agonist for relaxin receptor 1 (RXFP1). It binds to RXFP1 and preferentially activates the pERK pathway in cells expressing RXFP1, rather than cAMP. B7-33 serves as an antifibrotic agent and provides cardioprotective effects.Formula:C131H229N41O36SColor and Shape:SolidMolecular weight:2986.54Vortioxetine D8
CAS:Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Formula:C18H22N2SPurity:98%Color and Shape:SolidMolecular weight:306.5Phendioxan
CAS:Phendioxan is a biochemcial.Formula:C25H27NO5Color and Shape:SolidMolecular weight:421.4915(S)-15-methyl Prostaglandin E2
CAS:15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.Formula:C21H34O5Color and Shape:SolidMolecular weight:366.49ORG 2766
CAS:ORG 2766 is an ACTH 4-9 (H-Met(O)-Glu-His-Phe-D-Lys-Phe-OH) analog and neurotrophic peptide.Formula:C40H55N9O11SColor and Shape:SolidMolecular weight:869.99Onzigolide
CAS:Onzigolide (BIM-23A760) is a dual agonist for D2R and SSTR2 with strong dopamine and somatostatin properties.Formula:C86H116N16O12S4Color and Shape:SolidMolecular weight:1694.21Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Formula:C154H244N47F3O46S4Purity:98%Color and Shape:SolidMolecular weight:3675.12Synephrine hemitartrate
CAS:Synephrine hemitartrate, an alkaloid from Citrus aurantium, is a sympathomimetic for weight loss, with α and β-adrenergic action.Formula:C9H13NO2C4H6O6Color and Shape:SolidMolecular weight:242.26L-threo Lysosphingomyelin (d18:1)
CAS:L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).Formula:C23H49N2O5PColor and Shape:SolidMolecular weight:464.62Carbazochrome salicylate
CAS:Carbazochrome salicylate can be used as a coagulant.Formula:C17H18N4NaO6Color and Shape:White Crystalline PowderMolecular weight:397.343Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
CAS:Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.Formula:C129H207N45O41S3Purity:99.78%Color and Shape:SoildMolecular weight:3140.5Semaglutide, FITC labeled
Semaglutide (FITC-labeled Semaglutide) is a long-acting analog of human glucagon-like peptide-1, functioning as an agonist of the GLP-1 receptor. It shows potential for research related to type 2 diabetes.Formula:C209H304N46O63SMolecular weight:4498.17191
