GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,018 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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K-(D-1-Nal)-FwLL-NH2
CAS:Potent ghrelin receptor inverse agonist with Ki of 4.9/31 nM in COS7/HEK293T; blocks Gq/G13 signaling.Formula:C51H67N9O6Purity:98%Color and Shape:SolidMolecular weight:902.13(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS:(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formula:C11H21NO4Purity:98%Color and Shape:SolidMolecular weight:231.29Cortistatin 29
Cortistatin 29: neuropeptide, relieves neuropathic pain, binds SS receptors (IC50: 2.8-13.7 nM), anti-fibrotic.Formula:C161H242N46O41S2Color and Shape:SolidMolecular weight:3539.77Mabuterol free base
CAS:Mabuterol: selective β2 agonist, inhibits isoprenaline, affects rat uterus and rabbit jejunum, alters intestinal propulsion.Formula:C13H18ClF3N2OPurity:98%Color and Shape:SolidMolecular weight:310.747-Methyl DMT
CAS:7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3CACPD2011a-0001278239
CAS:CACPD2011a-0001278239 is a β2AR hybrid agonist with high affinity binding to both the wild-type and T164I β2AR variants. It exhibits neither cytotoxicity nor mutagenicity, making it suitable for asthma research.Formula:C21H22N4O4Color and Shape:SolidMolecular weight:394.42PSB-SB-1203
CAS:PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.Formula:C25H30O4Color and Shape:SolidMolecular weight:394.5Afubiata
CAS:ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.Formula:C27H29FN2OColor and Shape:SolidMolecular weight:416.534-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColor and Shape:SolidMolecular weight:232.32Emoghrelin
CAS:Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].Formula:C24H22O13Purity:98%Color and Shape:SolidMolecular weight:518.42Invopressin
CAS:Invopressin (Compound 42), a vasopressin V1A receptor partial agonist (EC50: 1.0 nM), is utilized in research related to cirrhosis conditions such as bacterialFormula:C110H161N31O27S2Purity:98%Color and Shape:SolidMolecular weight:2413.78Antisauvagine-30
CAS:CRF2 receptor antagonist; Kd 1.4 nM (mCRF2β), 153.6 nM (rCRF1). Blocks sauvagine-induced cAMP in cells & stress-related responses in mice.Formula:C161H274N48O46SPurity:98%Color and Shape:SolidMolecular weight:3650.29(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
CAS:(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].Formula:C52H76N14O11S2Purity:98%Color and Shape:SolidMolecular weight:1137.38Neuropeptide Y (22-36)
CAS:Neuropeptide Y (22-36) is a 15-amino acid fragment of NPY, which is abundant in the mammalian brain and involved in multiple physiological functions.Formula:C85H139N29O21Purity:98%Color and Shape:SolidMolecular weight:1903.19[18F]-Labeled L-dopa precursor
CAS:[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa[1].Formula:C35H36N2O7Color and Shape:SolidMolecular weight:596.67ACTH (1-17)
CAS:ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.Formula:C95H145N29O23SPurity:98%Color and Shape:SolidMolecular weight:2093.41BQ-3020 ammonium
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2Formula:C96H140N20O25S·xNH3Purity:98%Color and Shape:SolidMolecular weight:2006.32 (free base)(R)-Citalopram oxalate
CAS:(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant
Formula:C22H23FN2O5Purity:99.76%Color and Shape:White SolidMolecular weight:414.43L-threo Lysosphingomyelin (d18:1)
CAS:L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).Formula:C23H49N2O5PColor and Shape:SolidMolecular weight:464.62
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