GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,018 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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Samelisant
CAS:Samelisant (SUVN-G3031), a selective H3 inverse agonist, Ki=8.7/9.8 nM in humans/rats, has anti-narcoleptic properties.Formula:C21H31N3O3Purity:99.59%Color and Shape:SolidMolecular weight:373.49Ref: TM-T9770
1mg105.00€2mg158.00€5mg260.00€10mg416.00€25mg687.00€50mg964.00€100mg1,288.00€500mg2,602.00€1mL*10mM (DMSO)268.00€PF-4348235 HCl
PF-4348235 HCl (β2AR/M-receptor agonist-2 HCl) is a muscarinic M3 receptor antagonist (Ki: 0.73 nM) and β2 adrenergic receptor agonist (MABA, EC50: 3.7 nM). PF-4348235 HCl is also a bronchial BM213 acetate is a bronchodilator used to study cardiovascular and respiratory diseases such as chronic obstructive pulmonary disease (COPD).
Formula:C36H50Cl2N4O7SPurity:98.81%Color and Shape:SolidMolecular weight:753.78α-Helical CRF(9-41) TFA
α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM.Formula:C168H275F3N46O55S2Color and Shape:SolidMolecular weight:3940.42Corazonin
CAS:Corazonin, a neuropeptide in insects, regulates caste identity and behavior, mainly in workers/foragers.Formula:C62H83N17O19Color and Shape:SolidMolecular weight:1370.42β-CGRP, human
CAS:β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascularFormula:C162H267N51O48S3Purity:98%Color and Shape:SolidMolecular weight:3793.41PG106 TFA
PG106 TFA is a potent hMC3 antagonist (IC50=210 nM), inactive at hMC4 (EC50=9900 nM) and hMC5 receptors.Formula:C53H70F3N13O11Color and Shape:SolidMolecular weight:1122.2Cortistatin-14 acetate
Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5).
Formula:C83H118N20O20S2Purity:98.24% - 99.63%Color and Shape:SoildMolecular weight:1780.08Human growth hormone-releasing factor TFA
Human growth hormone-releasing factor TFA is a hypothalamic peptide that promotes GH secretion by targeting pituitary GHRHR.Formula:C217H359F3N72O68SColor and Shape:SolidMolecular weight:5153.67K-(D-1-Nal)-FwLL-NH2 TFA
K-(D-1-Nal)-FwLL-NH2 TFA: potent ghrelin inverse agonist; Ki=4.9 nM (COS7), 31 nM (HEK293T); blocks Gq/G13 signaling.Formula:C53H68F3N9O8Color and Shape:SolidMolecular weight:1016.16(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
CAS:Analog of LHRH, stimulates LH and FSH release, controls reproduction.Formula:C59H84N18O14Color and Shape:SolidMolecular weight:1269.41CCZ01048 TFA
CCZ01048 TFA, α-MSH analog, binds MC1R with 0.31 nM affinity, internalizes in melanoma cells, and is stable for melanoma PET imaging.Formula:C73H106F3N21O18Color and Shape:SolidMolecular weight:1622.75RXFP3/4 agonist 1
CAS:RXFP3/4 agonist 1 is a relaxin family peptide 3/4 receptor (RXFP3/4) agonist(EC50s of 82/2 nM, respectivley).Formula:C20H22ClN5OPurity:98%Color and Shape:SolidMolecular weight:383.88SAR441255
SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptorsColor and Shape:Odour SolidPramlintide
CAS:Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer.Color and Shape:SolidNF157
CAS:NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.Formula:C49H28F2N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1437.1Octodrine
CAS:Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.Formula:C8H19NPurity:99.98%Color and Shape:Clear Colorless To Light Yellow LiquidMolecular weight:129.24Relamorelin TFA
CAS:Relamorelin (RM-131) TFA: ghrelin analog, GHSR agonist, 0.42 nM affinity, boosts growth hormone, enhances gastric emptying, potential in motility disorders.Formula:C45H51F3N8O7SColor and Shape:SolidMolecular weight:905Neuropeptide SF(mouse,rat) TFA
Neuropeptide SF TFA is a potent agonist for NPFF1 (Ki=48.4 nM) and NPFF2 (Ki=12.1 nM) and enhances ASIC3 current.Formula:C42H66F3N13O12Color and Shape:SolidMolecular weight:1002.05Bombinakinin M
CAS:Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.Formula:C100H159N31O24Purity:98%Color and Shape:SolidMolecular weight:2179.55Sar-[D-Phe8]-des-Arg9-Bradykinin
CAS:Potent bradykinin B1 agonist, EC50 = 9.02 nM, enzyme resistant, induces hypotension and angiogenesis.Formula:C47H66N12O11Purity:98%Color and Shape:SolidMolecular weight:975.11
![Sar-[D-Phe8]-des-Arg9-Bradykinin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1917.webp&w=3840&q=75)