Antibacterial

<p>Lansoprazole sulfide (AG-177) is an active metabolite of Lansoprazole .Lansoprazole is a proton pump inhibitor and antitubercular agents M.TB.</p>

<p>Chlorobutanol hemihydrate (Chlorbutol hemihydrate) is an antiseptic with antimicrobial activity, inhibiting Gram-positive and fungi.</p>

<p>3-Formyl rifamycin is a degradation product of Rifampicin, with antibacterial activity.</p>

<p>Metronidazole Benzoate, a salt of Metronidazole and benzoic acid, treats anaerobic infections with antibacterial and anti-parasitic properties.</p>

<p>Tiamulin fumarate (Thiamutilin fumarate) is an antibiotic with antimicrobial activity that inhibits protein synthesis and is used in the study of pneumocystitis</p>

<p>BC-7013, a pleuromutilin antibiotic, is ued potentially for the treatment of clostridial infection.</p>

<p>Stability Air Sensitive<br>Applications Levopimaric Acid is a major component of pine oleoresin. It is an abietane-type of diterpene resin acid and has antibacterial, cardiovascular, and antioxidant properties.<br>References Kersten, P. J., et al.: J. Chem. Ecol., 32(12), 2679-85 (2006)<br></p>

<p>Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.</p>

<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>

<p>Cetalkonium chloride, an ammonium preservative with anti-inflammatory properties, aids in aphthous ulcer research.</p>

<p>2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.</p>

<p>Tribromsalan (3,5,4'-Tribromosalicylanilide) is an inhibitor of Mycobacterium tuberculosis and abscess bacillus.</p>

<p>Cefuroxime (Cephuroxime) is a second-generation cephalosporin antibiotic with antimicrobial activity for the study of soft tissue infections.</p>

<p>Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells and can be used in the study of gastric ulcers.</p>

<p>5,6-Dihydroxyindole, a melanin precursor, exhibits wide antibacterial, antiviral, antifungal, and antiparasitic properties, and is cytotoxic to pathogens.</p>

<p>Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli and may be used to study infectious diseases.</p>

<p>Florfenicol amine hydrochloride is a veterinary antibiotic with antimicrobial activity that can be used to study diseases caused by Bartonella henselae.</p>

<p>Ionomycin is a calcium ionophore and a Ca2+ -binding antibiotic, increases intracellular Ca 2 + to induce cellular responses. High-Quality, Low-Cost!</p>

<p>Dermabond (2-Octyl cyanoacrylate) is a tissue adhesive commonly used for wound or surgical incision closure, with antibacterial properties.</p>

<p>Ceftolozane sulfate (FR-264205) is a cephalosporin antibiotic with broad-spectrum antimicrobial activity used in the study of pneumonia.</p>

<p>PF-04753299: potent LpxC inhibitor, kills gonococcus, fights E. coli/P. aeruginosa/K. pneumoniae; used in gram-negative bacteria research.</p>

<p>Golotimod (SCV 07) is an antimicrobial active dipeptide with immunomodulatory activity for the study of recurrent genital herpes simplex virus 2 infections.</p>

<p>Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.</p>

<p>Mtb ATP synthase-IN-1 is a potent, low-toxicity M. tuberculosis inhibitor with good oral bioavailability and metabolic stability.</p>

<p>Propiconazole (PRO) is an orally active brassinosteroid biosynthesis inhibitor and a triazole fungicide with antifungal activity.</p>

<p>Triclosan methyl-d3 (methoxy-d3) is a deuterated compound of Triclosan methyl. Triclosan methyl has a CAS number of 4640-01-1. Triclosan-methyl is a transformation product of triclosan. Triclosan is a bactericide in personal care products such as toothpaste, shampoos, and soaps. Triclosan is also a stabilizing agent in a multitude of detergents and cosmetics.</p>

<p>Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.</p>

<p>Norfloxacin-d8 is a deuterated compound of Norfloxacin. Norfloxacin has a CAS number of 70458-96-7. Norfloxacin(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.</p>

<p>Sulfasalazine-d4 is a deuterated compound of Sulfasalazine. Sulfasalazine has a CAS number of 599-79-1. Sulfasalazine is a synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug</p>

<p>Ethambutol-d8 is a deuterated compound of Ethambutol. Ethambutol has a CAS number of 74-55-5. Ethambutol is a bacteriostatic antimycobacterial agent obstructed the formation of cell wall by inhibiting arabinosyl transferases.</p>

<p>Penicillin V-d5 is a deuterated compound of Penicillin V. Penicillin V has a CAS number of 87-08-1.</p>

<p>Amoxicillin D4 (Amoxycillin D4) is a deuterium-labeled Amoxicillin. Amoxicillin is an antibiotic with broad-spectrum antimicrobial activity.</p>

<p>Oxacillin (Oxabel) is an antibiotic of the penicillin class, which exerts bactericidal effects by inhibiting bacterial cell wall synthesis.</p>

<p>Salinazid (Salicylaldehyde isonicotinoyl hydrazone) is a potent Cu(II) ionophore which preferentially kills HepG2 cells over HUVEC cells, and is superior to</p>

<p>Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.</p>

<p>β-Chloro-L-alanine (L-β-Chloroalanine), a bacteriostatic amino acid analog, inhibits a number of enzymes, including threonine deaminase and alanine racemase.</p>

<p>Gremubamab (MEDI3902) is a bivalent humanised monoclonal antibody, binds to PAPcrV protein and Psl extracellular polysaccharide, Pseudomonas aeruginosa.</p>

<p>1-O-(4-Hydroxybenzoyl)-glycerol is an antibacterial agent that inhibits the growth of Staphylococcus aureus, Escherichia coli, Saccharomyces cerevisiae, and Fusarium culmorum, achieving a maximum inhibition rate of 70% at 20 mM. It exhibits mild skin irritancy.</p>

<p>Cefaloridine: first-gen cephalosporin derivative, zwitterionic, treats pneumococcal pneumonia, effective against staph and strep.</p>

<p>NSC 31156 is a bioactive chemical.</p>

<p>Brobactam is a beta lactamase inhibitor with antibacterial activity.</p>

<p>Tosylchloramide sodium salt is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant.</p>

<p>Saccharin sodium is a type of artificial or nonnutritive sweetener. Saccharin sodium is used in the production of various foods and pharmaceutical products.</p>

<p>6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-, derived from 2,3-Bis(bromomethyl)quinoxaline, displays antibacterial properties.</p>

<p>Tosatoxumab (AR-301; KBSA301) is a fully human immunoglobulin-class monoclonal antibody that targets and neutralises S. aureus α-toxin antibiotic-adjuvant</p>

<p>Panobacumab (KBPA101) is a human IgM/κ monoclonal antibody targeting P. aeruginosa serotype O11 LPS O polysaccharide.</p>

<p>FOL7185 is an inhibitor of IspD and IspE enzymes isolated from bacteria.</p>

<p>Proflavine dihydrochloride is a topical antiseptic.</p>

<p>Dihydrostreptomycin is an antibiotic.</p>

<p>Acediasulfone is an antibiotic. It is used to treat ear infections.</p>

<p>Fibracillin is a penicillin antibiotic.</p>

<p>Pagibaximab, a chimeric IgG1, targets lipoteichoic acid to prevent staph sepsis from S. aureus/epidermidis.</p>

<p>Edetate Sodium (Trilon B, Na₄EDTA) is a metal chelating agent that binds to divalent and trivalent metal cations, antibacterial and anticoagulant.</p>

<p>the primary metabolite of ceftiofur</p>

<p>Omodenbamab (514-G3) is a humanised monoclonal antibody that neutralises SpA (Staphylococcus Protein A), on the cell wall of S. aureus.</p>

<p>Bezlotoxumab is a monoclonal antibody that binds Clostridium difficile toxin B, preventing epithelial damage, colitis, and infection recurrence.</p>

<p>Demecycline is an antibiotic.</p>

<p>Azlocillin is a semisynthetic ampicillin-derived penicillin belonging to acylureido.</p>

<p>Suvratoxumab (MEDI4893) is a long-lasting humanized IgG1κ monoclonal antibody targeting S. aureus α-toxin, enhancing survival in pneumonia.</p>

<p>"Sulfacytine, an oral short-acting sulfonamide antibiotic, treats infections by blocking bacterial folic acid synthesis."</p>

<p>NSC 31153 is a bioactive chemical.</p>

<p>Obiltoxaximab is a monoclonal antibody targeting the free protective antigen (PA) of Bacillus anthracis, inhalational anthrax</p>

<p>Methicillin: Narrow-spectrum beta-lactam, penicillin-type antibiotic for certain gram-positive bacterial infections.</p>

<p>Benzoxiquine (NSC 3951) is a cosmetic biocide that inhibits oral microbial growth and in vitro plaque formation.</p>

<p>Propylparaben-d4 is a deuterated compound of Propylparaben. Propylparaben has a CAS number of 94-13-3. Propylparaben is an antimicrobial agent, preservative, flavouring agent</p>

<p>Clavulanate potassium,β-Lactamase inhibitor with antibiotic activity.</p>

<p>Cortisol-1,2-d2 is a deuterated compound of Cortisol. Cortisol has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. Therapeutic Hydrocortisone is a synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects.</p>

<p>Ethyl parahydroxybenzoate-d4 is a deuterated compound of Ethyl parahydroxybenzoate. Ethyl parahydroxybenzoate has a CAS number of 120-47-8. Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.</p>

<p>Dodine: fungicide for scab in apples/pears/pecans, peach brown rot, foliar diseases in strawberries/cherries, and as biocide/preservative.</p>

<p>Trimosulfa is a combination of trimethoprim and sulfamethoxazole, an antibiotic combination. Sulfamethoxazole inhibits dihydropteroate synthase, while trimethoprim inhibits dihydrofolate reductase (dihydrofolate reductase), making it effective for mild to moderate bacterial infections against many Gram-negative and Gram-positive bacteria.</p>

<p>Golotimod TFA (SCV 07 TFA) is a dipeptide exhibiting immunomodulatory and antibacterial activity, alleviates radiation-induced oral mucositis.</p>

<p>Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.</p>

<p>Sulisatin, a laxative, becomes BHMI in the large intestine, causing its effect.</p>

<p>Saccharin sodium salt hydrate, a sweetener for foods and diabetic diets, has been probed for carcinogenicity.</p>

<p>Ro 20-0657/000 is a metabolite of Trimethoprim, a dihydrofolate reductase inhibitor used as an antibacterial in medicine.</p>

<p>DprE1-IN-10 (hit 2), an inhibitor of Decaprenylphosphoryl-β-D-ribose-2′-epimerase (DprE1), holds potential for the study of tuberculosis.</p>

<p>Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.</p>

<p>Olanexidine gluconate is an antiseptic/disinfectant compound with potent bactericidal activity against Gram-negative and Gram-positive bacteria.</p>

<p>Chloramphenicol palmitate is a broad-spectrum antibiotic effective against various bacteria and used for bacterial selection in gene studies.</p>

<p>Benzoylacetone (AI3 10572) exhibits antibacterial activity.</p>

<p>N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone has antibacterial activity.</p>

<p>Cephradine monohydrate is a β-lactam cephalosporin antibiotic exhibiting broad-spectrum activity against Gram-positive and Gram-negative pathogens.</p>

<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>

<p>Lapyrium, a biocide/antistatic cationic surfactant in personal care, also treats waste-water/corrosion as chloride salt.</p>

<p>C18G, a synthetic α-helical peptide derived from human platelet factor IV, exhibits biological activity with pronounced antibacterial properties against</p>

<p>Sulfiram is an ectoparasiticide and is a drug applied topically to treat scabies.</p>

<p>Sulfathiazole Sodium is an organosulfur compound. It also has been used as a short-acting sulfa drug.</p>

<p>BB2-50F is a potent, multi-targeting bioenergetic bactericidal inhibitor of M. tuberculosis that sterilizes both replicating and non-replicating M. tuberculosis. It inhibits succinate oxidation, decreases the activity of the tricarboxylic acid (TCA) cycle, and results in succinate secretion from M. tuberculosis. [1]</p>

<p>21272541 is a potent FabI protein inhibitor that significantly reduces infections caused by Gram-negative organisms [1].</p>

<p>PPM1A-IN-1 (Compound IV-4) is an inhibitor of the PP2C Ser/Thr protein phosphatase Mg2+/Mn2+-dependent 1A. It exhibits antibacterial activity against Mycobacterium tuberculosis.</p>

<p>cis-Nerolidol, a sesquiterpene alcohol present in numerous plants, exhibits antioxidant and antibacterial properties.</p>

<p>Bacampicillin is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.</p>

<p>GWP-042 is an effective inhibitor of Mycobacterium alanine dehydrogenase (Ald) Rv2780, with an IC50 of 0.21 μM. It exhibits antibacterial activity against Mycobacterium tuberculosis (M. tuberculosis) infections in vivo.</p>

<p>Stearyldiethanolamine (2,2'-(Octadecylazanediyl)diethanol) can be used in studies about antibacterial nonwoven fabric and antibacterial freshness-keeping film.</p>

<p>Ceftezole: alpha-glucosidase inhibitor, anti-diabetic, broad-spectrum antibiotic for gram-positive/negative bacteria.</p>

<p>Applications Protected Kanamycin A (K137500). Antibiotic complex produced by Streptomyces kanamyceticus Okami &amp; Umezawa from Japanese soil. Comprised of three components, kanamycin A, the major component, and kanamycins B and C, two minor congeners. Antibacterial.<br>References Ito, et al.: J. Antibiot., 17, 189 (1964), Toda, S., et al.: J. Antibiot., 30, 1002 (1977), Claes, P.J., et al.: Anal. Profiles Drug. Subs., 6, 259 (1977),<br></p>

<p>Norvancomycin hydrochloride (Desmethyl-vancomycin hydrochloride) is used as a treatment for endocarditis, osteomyelitis, pneumonia, sepsis, or soft tissue</p>

<p>Polyquaternium-1: a mild eye-safe preservative that inhibits microbes in multi-dose ophthalmic meds.</p>

<p>DHDPS-IN-1 (compound 8), a DHDPS inhibitor with 39 μM IC50, has potential in antibacterial and herbicidal applications.</p>

<p>4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor and a potential anti-tuberculosis (TB) agent [1].</p>

<p>MMV676584 has anti-tuberculosis avtivity. MMV676584 is a novel drug candidate for eumycetoma .</p>