Polycyclic Compounds

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<p>2-Hydroxyquinoline-4-carboxylic acid is a carboxylate that is structurally classified as a multidrug. It has been shown to inhibit bacterial efflux pumps and target enzymes, such as cancer cells and multidrug resistant bacteria. 2-Hydroxyquinoline-4-carboxylic acid also has potent antibacterial activity against Streptococcus faecalis, an opportunistic pathogen that causes infections in the urinary tract and on skin wounds. The fluorescence properties of this compound can be used for fluorescent labeling of biomolecules or for sensing applications.</p>

<p>Please enquire for more information about (1-Chloroisoquinolin-4-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Bromo-2-methylquinoline is a naphthalene derivative that has an oxidant function. It can be used as a solvent for chlorobenzene and as a catalyst for the production of bipyridines and piperazine. 8-Bromo-2-methylquinoline is also used as a ligand in the preparation of metal complexes. This compound reacts with methyl groups, chlorine, and halides to form methyl quinolines and dichloromethanes. 8-Bromo-2-methylquinoline may react with fatty acids to form polyunsaturated acid esters or with polyunsaturated fatty acids to form polyethers.</p>

<p>1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline is a chemical compound that has been used as an intermediate in the synthesis of pharmaceuticals. It is also a useful building block for the production of other chemicals. This compound is soluble in water. 1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline has shown to be a versatile and high quality reagent with many research applications.</p>

<p>Boc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid is a synthetic opioid that is chemically related to morphine. It binds to the δ opioid receptor and has a clinical development in the treatment of pain. The drug has been shown to inhibit the binding of gtpγs, which leads to the suppression of neuronal activity. Boc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylic acid also has low molecular weight and low toxicity.</p>

<p>Tetrahydroquinoline-3-carboxylic acid is a crystalline, water-soluble compound. It is an intermediate in the synthesis of l-phenylalanine, paraformaldehyde and formaldehyde. Tetrahydroquinoline-3-carboxylic acid can be hydrolyzed to produce formic acid and hydrogen chloride. This product is also optically active and can be used as an indicator for hydroiodic acid.</p>

<p>1,4-Diazabicyclo[2.2.2]octane is an organic compound that belongs to the group of coordination compounds and has antimicrobial activity. It is a colorless solid with a melting point of -117°C and a boiling point of 245°C. The molecular geometry is planar, which means that all bonds are linear. The compound can be found in water vapor or as colloidal gold sols in reaction with water vapor. It can also be obtained by reacting triethylenediamine with hydrochloric acid at 100°C under vacuum conditions. 1,4-Diazabicyclo[2.2.2]octane has been shown to have antibiotic properties and is able to inhibit the growth of bacteria through coordination geometry and phase transition temperature effects on the bacterial cell membrane.</p>

<p>Please enquire for more information about Quinoline-6-sulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1H-Cyclopenta[l]phenanthrene is a five-membered cyclic hydrocarbon that binds to phosphine and is used in the synthesis of ferrocenes. It is also unsymmetrical and anion-forming. 1H-Cyclopenta[l]phenanthrene can be protonated at carbon, which makes it a good ligand. 1H-Cyclopenta[l]phenanthrene has been shown to react with carbonyls, imines, and ethylene to form organometallic complexes.</p>

<p>Please enquire for more information about 4-Chloroquinoline-6-carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-(3-Carboxypropyl)-3,7-dimethylxanthine is a drug that belongs to a class of drugs called multidrugs. It has been shown to inhibit the growth of endothelial cells by blocking the binding of tnf-α to its receptor on these cells. 1-(3-Carboxypropyl)-3,7-dimethylxanthine also inhibits cancer cell proliferation and has been shown to be effective in some human cancer models. This drug interacts with other molecules (e.g., proton) and can have significant effects on magnetic resonance spectroscopy assays as well as in humans.</p>

<p>Please enquire for more information about 4-(Methoxycarbonyl)bicyclo[2.1.1]hexane-1-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>7-Methoxy-8-hydroxy-4-phenylcoumarin is a coumarin derivative, a type of organic compound characterized by a benzopyrone structure. This compound is typically derived from natural plant sources or synthesized in laboratory settings. Its structural features, such as the methoxy and hydroxy groups, are integral to its potential biological activity.</p>

<p>Fraxetin is a chemical compound known as a coumarin derivative, which is a natural product primarily sourced from various plant species. As a member of the coumarin family, fraxetin is often extracted from the roots, bark, and leaves of plant sources like Fraxinus species and other related flora. The compound operates through an array of biochemical pathways, prominently exhibiting antioxidant and anti-inflammatory properties. It acts by scavenging free radicals and modulating oxidative stress-related pathways, while also influencing the expression of various inflammatory cytokines.</p>

<p>Methyl (1R,2S,3S)-8-(3-Fluoropropyl)-3-(4-Iodophenyl)-8-Azabicyclo[3.2.1]Octane-2-Carboxylate is a potent dopamine receptor agonist with a high affinity for the D2 and D3 receptors in the brain. It has been shown to have antiparkinsonian effects in animal models of Parkinson's disease by increasing dopamine levels in the prefrontal cortex and striatum. This drug has also been shown to be effective in clinical studies for the diagnosis of Parkinson's disease. Methyl (1R,2S,3S)-8-(3-Fluoropropyl)-3-(4-Iodophenyl)-8-Azabicyclo[3.2.1]Octane-2-Carboxylate binds to both dopamine and serotonin receptors, which may account for its therapeutic effects on Parkinson</p>

<p>Please enquire for more information about 5-Amino-3,7-dimethylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Azaspiro[4.4]nonane hydrochloride is a versatile building block that is also used in research, as a reagent, and as a speciality chemical. It has been shown to be an excellent building block for complex compounds, with wide applications in the pharmaceutical industry. 1-Azaspiro[4.4]nonane hydrochloride has a CAS No. of 1417567-64-6 and can be found under the trade name Azapropynalene Hydrochloride (AP). It is soluble in water, alcohols, ethers and acetone but insoluble in most other solvents. 1-Azaspiro[4.4]nonane hydrochloride has been shown to have high quality and stability when stored under appropriate conditions; it is also resistant to degradation by light or air.</p>

<p>5-Amino-8-hydroxyquinoline dihydrochloride (5-AQDH) is an anticancer drug that inhibits the activity of survivin, a protein that is overexpressed in cancer cells. It has been shown to be effective in vivo against melanoma tumor growth. 5-AQDH binds to the unpaired cysteine residues of the survivin molecule and inhibits its function by binding to the active site, blocking access to ATP and preventing DNA synthesis. The efficacy of 5-AQDH has been confirmed in vitro by studying the effect on cell viability and DNA synthesis, as well as by measuring plasma mass spectrometry data from melanoma patients. This drug is currently being investigated for its potential use as an anticancer agent.</p>

<p>2,3,3-Trimethyl 5-methoxy indolenine (TMMI) is a fluorescent probe that has been used in photodynamic therapy. TMMI is chemically stable and has an unsymmetrical heterocycle with optical properties that allow it to be excited by green light at wavelengths of 540 nm. TMMI can be used to image hypoxic regions of the brain. This molecule has also been used as an enhancement agent for neovascularization and angiography. TMMI can be synthesized using mesoporous silica nanoparticles and halogens such as chlorine or bromine.</p>

<p>5,7-Dichloro-8-hydroxyquinoline (5,7-DC8HQ) is a mitochondrial drug that inhibits mitochondrial functions by binding to the ATP synthase. It has been shown to be effective against bacteria resistant to antimicrobial agents in vivo and also showed genotoxic activity in vitro. 5,7-DC8HQ binds to the magnesium site of the ATP synthase protein and prevents the formation of an intramolecular hydrogen bond, which leads to inhibition of ATP synthesis. This drug has also been shown to cause membrane potential depolarization in mitochondria.</p>

<p>Please enquire for more information about Methyl 1,5-dimethyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benazeprilat is a prodrug that is metabolized to enalaprilat, its active form. It is an inhibitor of angiotensin-converting enzyme (ACE) and has been shown to be effective in the treatment of heart failure. It has also been shown to inhibit ACE activity in vitro and in experimental models of congestive heart failure. Benazeprilat binds to the active site on the ACE molecule and inhibits the conversion of angiotensin I into angiotensin II, which causes vasoconstriction and stimulates aldosterone release from the adrenal cortex. This drug also has effects on energy metabolism by stimulating beta oxidation, which leads to increased levels of ketone bodies in blood plasma.</p>

<p>Please enquire for more information about 5-Bromo-3-[2-(1-pyrrolidinyl)ethyl]-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Xanthoxyletin is a coumarin, which is a type of natural organic compound commonly found in plants, particularly in the Rutaceae family. It is sourced from various plant species, including Zanthoxylum, known for their ethnobotanical uses. Xanthoxyletin functions primarily through its biochemical activity, including the inhibition of certain enzymes and modulation of cellular pathways that influence its pharmacological effects.</p>

<p>Please enquire for more information about 4,7-Diazaspiro[2.5]octane dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone is a crystalline organic base. It is used as an intermediate in the synthesis of piperazine derivatives. 3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone can be used to acetylate phenols and amines. This compound also has been shown to be useful in the industrial production of carbostyril and other pharmaceuticals. 3,4-Dihydro-7-(4-chlorobutoxy)-2(1H)-Quinolinone is also a high yield coupling agent for the production of heterocyclic compounds such as 1,5,6,8-tetrahydropyrimidines and benzimidazoles.</p>

<p>Poly(1,2-dihydro-2,2,4-trimethylquinoline) is a high molecular weight polymeric quinoline. It is an intramolecular hydrogen bond donor. The nitrogen atoms in the polymers are bound to hydrogen and form a ring with two amino groups. Poly(1,2-dihydro-2,2,4-trimethylquinoline) has been shown to be resistant to many chemical agents such as hydrogen fluoride and glycoside derivatives. It also has a carcinogenic potential and can induce liver lesions. The carcinogenesis studies of poly(1,2-dihydro-2,2,4-trimethylquinoline) have shown that it may cause cancer in animals via diazonium salt and methyl ethyl hydrochloric acid</p>

<p>Timapiprant is an amide that acts as a selective inhibitor of the prostanoid receptor CRTH2, which is involved in regulating the inflammatory response. Timapiprant inhibits skin eosinophilia, which is associated with inflammatory skin diseases such as atopic dermatitis and psoriasis. It has been shown to be safe in clinical trials and has a good safety profile. The drug's mechanism of action may be due to its ability to inhibit the production of IL-4 and IL-13 by Th2 cells and its ability to inhibit lung function. Timapiprant has shown efficacy in treating allergic rhinitis, asthma, chronic obstructive pulmonary disease, erythema multiforme, pyoderma gangrenosum, and other types of inflammatory skin diseases.</p>

<p>5-Nitrosoquinolin-8-ol is a chemical inhibitor that can be used in the study of enzyme function. It reacts with the active site of the enzymes and prevents them from carrying out their normal functions. 5-Nitrosoquinolin-8-ol has been shown to inhibit the growth of cancer cells and to have antiinflammatory properties. 5-Nitrosoquinolin-8-ol has been shown to bind to sephadex G-100 and potassium dichromate, which are both types of ion exchangers. The redox potential for this compound is -0.84 V. This means it will not react easily with other compounds, which makes it a good candidate for use as an inhibitor in biochemical studies. The nitrogen atoms in this compound are reactive, which means they can form covalent bonds with other molecules in a reaction called nitrosation. Structural biology is a branch of science that deals with studying the three dimensional structure of biological mac</p>

<p>Indole-3-acetyl-L-glutamic acid is an endogenous substance that is found in plants. It is the conjugated form of indole-3-acetaldehyde and L-glutamic acid. Indole-3-acetylglutamic acid has shown to have antioxidant potential and can be used to regulate plant growth, as well as protect against environmental stresses. Indole-3-acetylglutamic acid also has a role in regulating the production of other hormones, such as ethylene and auxin, which are involved in plant growth regulation.</p>

<p>Please enquire for more information about (S)-5,6,6a,7-Tetrahydro-6-methyl- 4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Methyl-1H-imidazole-5-carboxylic acid is a molecule that belongs to the class of antibiotics. It has been shown to be an effective inhibitor of lipases and other enzymes, which is due to its carboxylate group. The immobilization of this molecule has been studied by X-ray crystallography. The oxygen atoms in the molecule are covalently immobilized on a silica surface via a linker chain, which prevents the loss of these atoms. Dichroism spectroscopy was used to study the effects of different solvents on this molecule's ability to rotate light. 2-Methyl-1H-imidazole-5-carboxylic acid was also successfully immobilized using an enzyme called lipase, with residue carboxylate groups positioned at the bottom of the binding cavity.</p>

<p>Anhydrobyankangelicin is a coumarin derivative, which is a specialized type of organic compound commonly found in the plant family Apiaceae. This compound is biosynthetically sourced from the roots of plants such as Angelica species, where it is observed in varying concentrations. Anhydrobyankangelicin operates through interactions with several biological pathways, including modulating calcium channels and inhibiting certain enzymes involved in oxidative stress. This mechanism of action contributes to its efficacy in providing neuroprotective effects.</p>

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<p>Ethyl 1,2-dimethyl-5-hydroxyindole-3-carboxylate (EDMC) is an implantable drug that is used to treat hypertension. It is a diuretic that can be taken orally or injected. EDMC works by reducing the amount of urea nitrogen in the blood and increasing the amount of chlorine atom in the urine. This leads to an increase in active substances such as malonic acid and a decrease in arthropoda. EDMC has been shown to have antihypertensive activity due to its ability to lower diastolic and systolic pressure. The molecule also contains hydroxyl group and aldehyde groups that are analyzed by analytical chemistry.</p>

<p>4-Hydroxy-7-methoxyquinoline is an anti-malarial drug that belongs to the class of trimethyl, trifluoromethyl group. It is a cyclic compound and its synthesis starts with cyclization of the methyl derivative, which forms a ring. This product is used in clinical practice as an inhibitor of malarial protozoa and has been shown to have mechanistic effects on the cytochrome bc1 complex containing red blood cells. 4-Hydroxy-7-methoxyquinoline also inhibits the growth of bacteria by binding to the enzyme methionine synthase, which is involved in the biosynthesis of methionine from homocysteine. The product also has an inhibitory effect on DNA synthesis and protein synthesis.</p>

<p>7,8-Methylenedioxycoumarin is a furanocoumarin compound, which is a type of organic molecule characterized by a coumarin core with an additional methylenedioxy group. It is primarily sourced from various plant species, particularly those in the Rutaceae family, where it is found in essential oils and extracts. The mode of action of 7,8-Methylenedioxycoumarin involves its natural fluorescing properties, making it highly valuable for use in various biochemical assays where visualization is key. Due to its unique chemical structure, it efficiently absorbs ultraviolet light and emits visible fluorescence, which is exploited in photochemistry and as a biological marker. Its applications extend to the fields of pharmaceuticals and environmental sciences, where it serves in drug development studies and as a tool for tracking organic pollutants in ecosystems. Researchers continue to explore its potential uses due to its distinctive chemical behavior and natural origin.</p>

<p>7,8-Dihydroxy-4-methylcoumarin is a bioactive compound, specifically a derivative of coumarin. This compound is naturally derived from plant sources, where it acts as a metabolite in various biochemical pathways. Its chemical structure is characterized by the presence of two hydroxyl groups at the 7 and 8 positions, along with a methyl group at the 4 position of the coumarin core, contributing to its unique pharmacological profile.</p>

<p>1,2-Dihydrobenzene (1,2-DH) is a molecule that has the chemical formula C6H6. It is a colorless liquid with boiling point of 147°C and melting point of -11°C. 1,2-DH has been shown to form hydrogen bonds with water molecules. This compound is also insoluble in water, which may be due to its dehydrating properties. When catalyzed by an acid or base, 1,2-DH undergoes dehydration reactions. Acidic or basic conditions are required for this reaction to occur and the resulting product can be determined by x-ray diffraction studies. 1,2-DH has been shown to form coordination complexes with metal ions such as copper (Cu) and zinc (Zn). These complexes have been shown to have ligand binding properties that lead to supramolecular structures. Intermolecular hydrogen bonding interactions between 1,2-DH molecules have also been observed during</p>

<p>Please enquire for more information about 6-Benzyloxy-5-methoxyindole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Methylquinoline is an organic compound that can be used to synthesize antimalarial drugs. It is a quinoline derivative with a methyl group at the 7th position. The structure of 7-methylquinoline contains a nitrogen atom and hydrogen atoms, which are bonded to fluorine, chlorine, and bromine atoms. This molecule has been shown to be stable in the presence of Friedel-Crafts catalysts and chloride ions. The reaction mechanism for 7-methylquinoline is intramolecular hydrogen transfer from the chloroform molecule to the quinoline ring system. The formation rate for this compound is slow because it requires two steps: nucleophilic substitution and electrophilic addition reactions.</p>

<p>Please enquire for more information about 1-Allyl-3,7-dimethyl-8-phenylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tomenin is a systemic insecticidal compound, which is synthetically derived with a unique dual mode of action. This product is designed to efficiently target nematodes, plant-parasitic organisms that cause significant agricultural damage. The molecular formulation of Tomenin involves binding to specific nematode receptors, disrupting their neuromuscular functions and metabolic pathways. This dual action results in paralysis and eventual death of the nematodes, ensuring effective control over populations that threaten crop yield and quality.</p>

<p>1,3-Dipropyl-7-methylxanthine is a xanthine compound that is structurally related to caffeine. It has been shown to have an inhibitory effect on the production of reactive oxygen species and cytosolic calcium levels in primary cells, as well as a nonselective adenosine receptor antagonist activity. It has also been shown to antagonize the effects of adenosine receptors, p2 receptors, and p2y receptors. This drug is used for the treatment of basophilic leukemia.</p>

<p>cis-Khellactone is a naturally occurring organic compound, which is a type of coumarin derivative sourced predominantly from the roots of Peucedanum and Angelica species, plants native to various regions. These botanical sources are known for yielding secondary metabolites with diverse biological properties.</p>

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<p>Trans-decahydroquinoline is a chiral compound that can be synthesized by an asymmetric synthesis. It is an amide with a carbonyl group and a dialkylamino group. Trans-decahydroquinoline can be used to synthesize different compounds, such as enantiopure drugs, pharmaceuticals, and agrochemicals. The synthesis of trans-decahydroquinoline can be accomplished through the aldol cyclization or the addition of an acid to the carbonyl group. The magnetic resonance spectroscopy (NMR) and molecular modeling techniques have been used to study its structure and properties.</p>

<p>(S)-1,2,3,4,5,6,7,8-Octahydro-1-[(4-methoxyphenyl)methyl]isoquinoline (acetate salt ) is a diphosphine that can be used as a catalyst to produce formic acid from methanol and carbon monoxide. This product is an enantiomer of picric acid and has been shown to be an effective additive in the crystallization of picric acid. The acetate salt is also optically pure.</p>

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<p>Please enquire for more information about 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ostruthin is a naturally occurring coumarin derivative, which is isolated from plants such as *Peucedanum ostruthium* and other species within the Apiaceae family. It functions as an enzyme inhibitor, acting primarily through its interference with various cellular processes, including the inhibition of specific enzyme pathways that contribute to its bioactivity. Ostruthin exhibits a range of biological activities, making it of significant interest in pharmacological research.</p>

<p>4-Hydroxy-3-nitro-2(1H)-quinolinone is a quinoline derivative that has been shown to have anticancer activity against cancer cells. It can be used for the treatment of various types of cancer, including lung cancer, breast cancer, and colon cancer. This drug inhibits the growth of cancer cells by blocking the cycle at the G1 phase and inducing apoptosis. It also disrupts mitochondrial membrane potential, leading to an increase in reactive oxygen species and DNA damage. 4-Hydroxy-3-nitro-2(1H)-quinolinone is an epidermal growth factor receptor (EGFR) antagonist and blocks epidermal growth factor signaling through its inhibition of EGFR tyrosine kinase activity. It also downregulates TNFα expression in tumor cells by inhibiting NFκB activation.</p>

<p>Please enquire for more information about Peuarin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Geranyloxycoumarin is a naturally occurring coumarin derivative, which is primarily sourced from plant species in the Rutaceae family. It is a bioactive compound known for its presence in various essential oils and its contribution to the properties of these plant extracts. The mode of action of 7-Geranyloxycoumarin involves interactions at the cellular level, including enzyme inhibition and modulation of signal transduction pathways, which can lead to diverse pharmacological effects.</p>

<p>5,7-Dihydroxycoumarin is a natural product isolated from the dichloromethane extract of the inflorescences of Macaranga triloba.</p>

<p>8-Benzyloxy-5-((R)-2-bromo-1-hydroxyethyl)-1H-quinolinone is a potassium channel blocker. It binds to the central cavity of the channel pore and blocks potassium ion flux, inhibiting the function of potassium channels. 8-Benzyloxy-5-(2-(R)-bromo-1,3-dihydroxypropyl)quinolinone has been shown to inhibit voltage gated channels in a number of different tissues, including cardiomyocytes from rat hearts.</p>

<p>Please enquire for more information about 1-Boc-4-aminoindole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Chloro-6,7-dimethoxyquinoline (4C6DMQ) is a potent inhibitor of the growth of prostate cancer cells. 4C6DMQ is an analog of chloropropyl chloride, which inhibits the growth of epidermal growth factor receptor (EGFR). The binding site for 4C6DMQ on EGFR is the same as that for chloropropyl chloride. 4C6DMQ inhibits EGFR by preventing the activation of downstream signaling cascades, leading to a decrease in cell proliferation and tumor size. The IC50 values for 4C6DMQ are approximately 10 times higher than those for chloropropyl chloride. This drug has been shown to be more potent than other inhibitors of EGFR such as erlotinib and gefitinib.</p>

<p>Indole-3-acetic-L-alanine is a plant hormone that regulates root formation and transport. It is found in all plants, but the concentration varies depending on the plant, tissue type, and growth conditions. It has been shown to regulate root formation in triticum aestivum by inhibiting auxin transport to the roots. Indole-3-acetic acid also inhibits auxin transport to the shoot apex, leading to increased branching in triticum aestivum. This compound is hydrolyzed by root cell enzymes into indole-3-acetate and L-alanine. Genetic mechanisms underlying this phenomenon are not well understood at this time.</p>

<p>6-Chloro-2-fluoropurine is an analytical reagent with a monoclonal antibody that binds to the nucleic acid of HL-60 cells and can be used for optical analysis. 6-Chloro-2-fluoropurine has been shown to have significant cytotoxicity against HL-60 cells, which may be due to its ability to bind to intracellular targets. 6-Chloro-2-fluoropurine has also been shown to inhibit the growth of HL-60 cells in a fluorescein angiography study and is used as a diagnostic agent for diagnosis of cancer.</p>

<p>Marmesinin is a furanocoumarin compound, which is a type of phytochemical derived from certain plant species. It is specifically obtained from the plant Aegle marmelos, commonly known as the bael tree. Marmesinin acts primarily through mechanisms that are characteristic of coumarins, such as influencing biochemical pathways involved in cellular growth and immune response modulation.</p>

<p>5-Chloro-8-hydroxyquinoline (5-CQ) is a quinoline derivative that has been used as an anticancer agent. It binds to DNA and inhibits the synthesis of RNA and proteins, leading to cell death. 5-CQ has been shown to be cytotoxic against skin cells in vitro by inhibiting mitochondrial oxidative phosphorylation and decreasing the mitochondrial membrane potential. This compound also has genotoxic effects on cultured choroidal neovascularization cells through the inhibition of DNA synthesis.<br>5-CQ binds to DNA via hydrogen bonds with nitrogen atoms in the purine ring of nucleobases. The overall geometry is that of a distorted octahedron with two faces, each containing six nitrogens in square planar coordination geometry. The binding constants are low for purines but high for pyrimidines, which is why 5-CQ preferentially targets purine rich regions of the genome.</p>

<p>Please enquire for more information about 5-Fmoc-amino-10,11-dihydro-5H-dibenzo[a,d]-cycloheptenyl-2-oxyacetyl-DL-Nle-4- methyl-benzhydrylamide resin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Peucedanol methyl ether is a bioactive natural compound, which is derived from certain species of the Peucedanum genus, commonly found in various geographic regions. This compound is predominantly obtained from natural extracts through advanced chromatographic techniques. Its molecular structure is characterized by its functional groups, which contribute to its biological activities.</p>

<p>7-Bromo-1H-indazole is a brominated indazole with an unusual amino acid sequence. It can be used as a building block for the synthesis of new compounds that have potential as medicines. 7-Bromo-1H-indazole has been investigated in cancer cell lines, and it has been shown to inhibit the growth of these cells by inhibiting the production of chloride ions. The molecular modeling of this compound has also shown that it may bind to the chloride channel on cancer cells, preventing chloride ions from entering or leaving the cell. The X-ray crystal structures show that 7-bromoindazole binds with hydrogen bonds to azobisisobutyronitrile (AIBN) and ruthenium complex, which are both potential anticancer drugs.</p>

<p>2-Aminoimidazole sulfate is a chemical compound that is used as a transfection reagent. It has been shown to have high transfection efficiency with low cytotoxicity. The diameter of the molecule is in the range of 2 - 3 nm, which allows it to be taken up by cells and thus be active in them. This chemical can be dehydrogenated to form imidazole-2-sulfonic acid, which may interact with other molecules. There have been many advances in this area, including modifications and gaseous forms of the molecule. Research into the interactions of this compound with other chemicals and their effects on cellular uptake are ongoing.</p>

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<p>4,10-Dioxatricyclo[5.2.1.02.6]dec-8-ene-3,5-dione (DTDE) is a hypoglycemic agent that inhibits the synthesis of fatty acids in the liver and reduces blood sugar levels by inhibiting the enzyme diacylglycerol acyltransferase 2 (DGAT2). DTDE has been shown to have antitumour activity against a human cell line and inhibits the replication of DNA and RNA by binding to amines in nucleic acid bases.</p>

<p>4,4'-Dimethyl-2,2'-bipyridine is a molecule that belongs to the group of p2 metal complexes. It has been shown to have synergistic effects with ruthenium complexes in analytical chemistry and electrochemical studies. Theoretical calculations have been performed for 4,4'-dimethyl-2,2'-bipyridine and its derivatives. These calculations show that the molecule is planar and that it can be considered as a diazonium salt. The photochemical properties of 4,4'-dimethyl-2,2'-bipyridine have also been studied in detail. This substance emits light when excited by ultraviolet light or visible light, which makes it an excellent candidate for use as a luminescent material in optical displays.</p>

<p>(+)-Peucedanol is a sesquiterpene compound, which is a type of natural organic compound composed of three isoprene units resulting in a 15-carbon backbone. It is derived from various species within the plant genus Peucedanum, known for their rich content of bioactive compounds. The stereoisomerism indicated by the "(+)" suggests a specific three-dimensional configuration that may influence its biological activity.</p>

<p>1-Acetylindoline is an endogenous compound that has been shown to have antioxidative activity. It is also a precursor of indole-3-acetic acid and has been shown to reduce the production of proinflammatory cytokines in vitro. 1-Acetylindoline has been found to have hypoglycemic effects in rats, which may be due to its ability to inhibit the release of insulin from pancreatic beta cells. This substance also possesses peptide hormone activities, being a potent inhibitor of prolactin release in vitro. 1-Acetylindoline has also been shown to have antihyperproliferative effects on prostate cancer cells by inducing cell cycle arrest and apoptosis.</p>

<p>H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl is a monoclinic crystalline compound. It has a molecular weight of 607.14 and contains the dipeptide Tyr-Lys in its structure. H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl crystallizes in the P21/c space group and has an asymmetric unit cell with dimensions a=8.851 Å, b=7.965 Å and c=5.98 Å. This compound has been shown to have antibacterial properties against methicillin resistant Staphylococcus aureus (MRSA) isolates and Clostridium perfringens strains by inhibiting bacterial protein synthesis through inhibition of peptidyl transferase activity.</p>

<p>1,5,7-Triazabicyclo[4.4.0]dec-5-ene is a model system for the reaction mechanism of protonated amines and nucleophilic addition reactions. It has been used as a solid catalyst for the synthesis of crystalline polymorphs of azabenzene from trifluoroacetic acid. The crystal structures of 1,5,7-triazabicyclo[4.4.0]dec-5-ene have been studied by X-ray diffraction data and nitrogen atoms were identified in the molecule. This molecule is stable in a wide range of conditions and can be handled without special precautions because it does not react with atmospheric moisture or oxygen.</p>

<p>6,7-Dihydro-5H-quinolin-8-one is a quinoline derivative that can be used to treat cancer. It is an inhibitor of topoisomerase II, which is an enzyme that catalyzes the formation of single stranded breaks in DNA and then reseals them. The inhibition of topoisomerase II leads to the accumulation of single strand breaks, which causes cell death. 6,7-Dihydro-5H-quinolin-8-one has been shown to have inhibitory activity against cancer cells in laboratory tests and also inhibits the growth of breast cancer cells in mice. This compound also has a number of other biological effects including being a ligand for some receptors and amine oxidases as well as having antihistamine properties.</p>

<p>Please enquire for more information about Oxindole-4-boronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about [4,4'-Di-t-butyl-2,2'-bipyridine][bis[5-(t-butyl)-2-[4-(t-butyl)-2-pyridinyl-kN]phenyl-kC]iridium(III) hexafluorophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 10H-[1,2,5,8,11,14,17,20,23,26,29,32,35]Dithiaundecaazacyclooctatriacontino[11,10-b]isoquinoline,cyclic peptide derivative including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Mercaptopurine (2MP) is a thiopurine drug that is used to treat bowel disease. 2MP inhibits the activity of methyltransferase, which is an enzyme that converts 6-mercaptopurine to 6-thioguanine. This process prevents the conversion of 6-thioguanine into 6-thiouric acid, which is an intermediate in the synthesis of thymine nucleotides. 2MP also inhibits the binding of atp-binding cassette transporter proteins to DNA and blocks the incorporation of purines into RNA and DNA. The drug has been shown to be effective in treating squamous cell carcinoma and other diseases with a high level of activity. 2MP has been shown to be metabolized by erythrocyte polymerase chain reaction and can be detected in biological samples.</p>

<p>Bioavailable form of vitamin B6; coenzyme; food supplement</p>

<p>Please enquire for more information about N2-(2-Tricyclo[3.3.1.13,7]dec-1-ylacetyl)-D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl- D-phenylalanyl-3-(2-thienyl)-L-alanyl-L-arginine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Fluoroisoindoline HCl is a versatile building block that can be used in the synthesis of complex compounds, research chemicals, and reagents. It is a high quality compound with a wide range of applications. 4-Fluoroisoindoline HCl is also useful as an intermediate for the synthesis of other compounds, or as a reaction component for organic chemistry reactions. This compound has been shown to have potential medical uses in the treatment of Parkinson's disease and cancer.</p>

<p>8-Quinolinesulfonyl chloride (8QSC) is a quinoline derivative that has been shown to have anticancer activity. 8QSC binds to the receptor site of cells and inhibits the production of amines, which are important for cell growth and proliferation. It also binds to hydrogen bonds, which may be involved in the cytotoxicity observed in pancreatic cancer cells. 8QSC shows significant cytotoxicity against Panc-1 cells, but not against NIH 3T3 cells. This may be due to its ability to form supramolecular aggregates with copper ions and quinoline derivatives.</p>

<p>6-Bromoindazole is a hydrogen bond inhibitor that has potential neuroprotective effects. It inhibits the enzyme DNA Gyrase, which is necessary for bacterial replication, and has antibacterial properties. 6-Bromoindazole interacts with the receptor tyrosine kinase axitinib and inhibits its activity. This interaction may be responsible for its neuroprotective effects.</p>

<p>Please enquire for more information about 2-Boc-2,9-Diazaspiro[5.5]undecane hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>1,1'-Carbonimidoylbis-1H-imidazole is a ligand that binds to amines and isosteres. It can be activated with electrophilic reagents to form an activated linker. This ligand has been shown to inhibit the growth of xenograft tumor cells in mice by binding to functional groups on the cell surface. This drug also has been shown to bind to the receptor for advanced glycation end products (RAGE) and inhibit its function. 1,1'-Carbonimidoylbis-1H-imidazole has also been evaluated as a cancer therapeutic agent in animal models.</p>