Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8625 produtos de "Metabolismo"
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Hydroxypyruvic acid
CAS:<p>Hydroxypyruvic acid: a metabolic intermediate for glycine, serine, threonine; used by serine-pyruvate aminotransferase, glyoxylate reductase.</p>Fórmula:C3H4O4Pureza:98%Cor e Forma:SolidPeso molecular:104.06DSPE-PEG1000-TAASGVRSMH
<p>DSPE-PEG1000-TAASGVRSMH is a PEG compound composed of DSPE and TAASGVRSMH. The TAASGVRSMH sequence exhibits high affinity for the NG2 proteoglycan on PC membranes. DSPE-PEG1000-TAASGVRSMH is useful for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG1000-VIP
<p>DSPE-PEG1000-VIP is a PEG compound composed of DSPE and the vasoactive intestinal peptide (VIP). It can be utilized for drug delivery.</p>Cor e Forma:Odour SolidEthyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS:<p>ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.</p>Fórmula:C12H10ClNO3Pureza:99.19%Cor e Forma:SolidPeso molecular:251.67Tetrachlorocatechol
CAS:<p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>Fórmula:C6H2Cl4O2Pureza:96.68%Cor e Forma:SolidPeso molecular:247.891-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol
CAS:<p>Triacylglycerol with palmitic, oleic, arachidonic acids at sn-1, sn-2, sn-3; found in rat retina lipid extracts.</p>Fórmula:C57H100O6Cor e Forma:SolidPeso molecular:881.421PDE2A-IN-1
CAS:<p>PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC 50 value of 1.3 nM.</p>Fórmula:C23H22F2N6Cor e Forma:SolidPeso molecular:420.468DSPE-PEG5000-PP1
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the PP1 peptide, which targets inflammatory atherosclerotic plaques. It can be used for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG2000-VIP
<p>DSPE-PEG2000-VIP is a PEG-based compound composed of DSPE and the vasoactive intestinal peptide (VIP). This compound is useful for drug delivery applications.</p>Cor e Forma:Odour SolidIsbufylline
CAS:<p>Isbufylline can exert significant anti-inflammatory actions, in addition to its bronchodilator activity.</p>Fórmula:C11H16N4O2Pureza:90% - 97.59%Cor e Forma:SolidPeso molecular:236.27DSPE-PEG5000-F3
<p>DSPE-PEG5000-F3 consists of DSPE and the nucleolin-targeting peptide (F3) and is a PEGylated compound. The F3 peptide specifically binds to nucleolin on the cell surface, facilitating efficient transport from the cell surface to the nucleus. DSPE-PEG5000-F3 is applicable for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG2000-pPB
<p>DSPE-PEG2000-pPB is a PEG compound comprised of DSPE and the cyclic oligopeptide (pPB). The pPB component exhibits a high binding affinity for PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB is utilizable for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG2000-ESBP
<p>DSPE-PEG2000-ESBP is a PEGylated compound composed of DSPE and E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Cor e Forma:Odour SolidDSPE-PEG5000-T7
<p>DSPE-PEG5000-T7 is a PEG-based compound composed of DSPE and transferrin receptor peptide (T7). T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG5000-T7 is applicable in drug delivery.</p>Cor e Forma:Odour SolidC12 DG PEG (MW 2000)
<p>C12 DG PEG (1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol) (MW 2000) is a polyethylene glycol lipid that can be utilized in the formation of lipid nanoparticles and liposomes. C12 DG PEG (MW 2000) shows potential for use in cancer research.</p>Cor e Forma:Odour SolidDSPE-PEG5000-SP94
<p>DSPE-PEG5000-SP94 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (SP94). SP94 demonstrates specific binding affinity to hepatocellular carcinoma (HCC) cells.</p>Cor e Forma:Odour SolidDSPE-PEG1000-CSTSMLKAC
<p>DSPE-PEG1000-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. The CSTSMLKAC component facilitates phage-mediated targeting to ischemic cardiac tissue. DSPE-PEG1000-CSTSMLKAC is applicable in drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG2000-ANG
<p>DSPE-PEG2000-ANG is a PEG compound composed of DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficiency to LRP1 and has been used for targeted delivery to gliomas. DSPE-PEG2000-ANG can be utilized in drug delivery applications.</p>Cor e Forma:Odour SolidPDE11A4-IN-1
<p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>Cor e Forma:Odour SolidDSPE-PEG5000-ANG
<p>DSPE-PEG5000-ANG is a PEGylated compound formed by DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficacy to LRP1 and has been utilized for targeting glioma delivery. DSPE-PEG5000-ANG is applicable in drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG1000-T7
<p>DSPE-PEG1000-T7 is a PEG compound composed of DSPE and transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR. DSPE-PEG1000-T7 is applicable in drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG5000-M2pep
<p>DSPE-PEG5000-M2pep is a PEG compound composed of DSPE and the M2 macrophage-targeting peptide (M2pep). Serving either as a monovalent or multivalent ligand, M2pep is conjugated with pro-apoptotic peptides to direct toxicity specifically toward M2 macrophages. DSPE-PEG5000-M2pep is applicable for drug delivery.</p>Cor e Forma:Odour SolidAcetoacetyl coenzyme A sodium
CAS:<p>Acetoacetyl-CoA sodium is a key metabolite, with a Km of 1.10 mM at pH 7.5, used in PTB and PHB synthesis.</p>Fórmula:C25H37N7Na3O18P3SCor e Forma:SolidPeso molecular:917.55DSPE-PEG5000-TH
<p>DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.</p>Cor e Forma:Odour Solid(S)-Higenamine
CAS:<p>(S)-Higenamine, a benzylisoquinoline precursor, forms from dopamine and 4-HPAA via NCS.</p>Fórmula:C16H17NO3Cor e Forma:SolidPeso molecular:271.31DSPE-PEG1000-EB1
<p>DSPE-PEG1000-EB1 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (EB1). It is utilized for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG3000-TAT
<p>DSPE-PEG3000-TAT is a PEG compound composed of DSPE and a cell-penetrating peptide (TAT). It is used for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG2000-PP1
<p>DSPE-PEG2000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide specifically targets inflammatory atherosclerotic plaques. DSPE-PEG2000-PP1 is utilized in drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG1000-LTLRWVGLMS
<p>DSPE-PEG1000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). The receptor for LLRWVGLMS is the chondroitin sulfate proteoglycan NG2. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG1000-LTLRWVGLMS can be utilized for drug delivery.</p>Cor e Forma:Odour SolidDSPE-PEG2000-NGR
<p>DSPE-PEG2000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide specifically targets the tumor vasculature antigen CD13. This compound is suitable for drug delivery applications.</p>Cor e Forma:Odour SolidHIV-IN-9
<p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>Cor e Forma:Odour SolidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Fórmula:C14H26Cl2N6O5Cor e Forma:SolidPeso molecular:428.13417FXIIa-IN-1 HCl
CAS:<p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>Fórmula:C21H17ClN2O6Pureza:99.61%Cor e Forma:SoildPeso molecular:428.82DSPE-PEG2000-T7
<p>DSPE-PEG2000-T7 is a PEG compound composed of DSPE and the transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR, making DSPE-PEG2000-T7 useful for drug delivery applications.</p>Cor e Forma:Odour SolidC14-490
CAS:<p>C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).</p>Fórmula:C86H177N5O7Cor e Forma:SolidPeso molecular:1393.35DSPE-PEG5000-LTLRWVGLMS
<p>DSPE-PEG5000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). Chondroitin sulfate proteoglycan NG2 serves as a receptor for LLRWVGLMS. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG5000-LTLRWVGLMS can be utilized for drug delivery.</p>Cor e Forma:Odour Solid5(S)-HPETE
CAS:<p>5(S)-HpETE is a PUFA made by 5-LO from arachidonic acid, metabolized into LTA4, a key leukotriene precursor.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472Galcuronokinase (AtGalAK)
<p>AtGalAK, a GHMP kinase, converts d-GalA to GalA-1-P using ATP.</p>Cor e Forma:Solid(-)-Jasmonoyl-L-isoleucine
CAS:<p>(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile), an enantiomer of (+)-JA-L-Ile [1], is an inactive endogenous hormone.</p>Fórmula:C18H29NO4Cor e Forma:SolidPeso molecular:323.43Sapropterin free base
CAS:<p>Sapropterin aids in amino acid breakdown and neurotransmitter synthesis, including dopamine and serotonin, and supports nitric oxide production.</p>Fórmula:C9H15N5O3Pureza:98%Cor e Forma:SolidPeso molecular:241.25Efmoroctocog alfa
CAS:<p>Efmoroctocog alfa, a recombinant human coagulation factor VIII-Fc fusion protein (rFVIIIFc), serves as a therapeutic agent for Hemophilia A research [1].</p>Cor e Forma:SolidAminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Fórmula:C12H16F2N2O4SCor e Forma:SolidPeso molecular:322.07988Cyclopenol
CAS:<p>Cyclopenol is a natural product that can be used as a reference standard. The CAS number of Cyclopenol is 20007-85-6.</p>Fórmula:C17H14N2O4Cor e Forma:SolidPeso molecular:310.309H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.Fórmula:C18H31N3O6Pureza:97.15%Cor e Forma:SolidPeso molecular:385.46N-Desethyl Bimatoprost
CAS:<p>N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide.</p>Fórmula:C23H33NO4Cor e Forma:SolidPeso molecular:387.51DSPE-PEG1000-NYZL1
<p>DSPE-PEG1000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to selectively bind to bladder cancer tissues and cells. This compound is applicable for drug delivery purposes.</p>Cor e Forma:Odour SolidPDE5-IN-10
<p>PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,</p>Fórmula:C21H20N4O2Cor e Forma:SolidPeso molecular:360.415′-Nucleotidase
CAS:<p>5′-Nucleotidase (CD73), an ectoenzyme and intrinsic membrane glycoprotein, catalyzes the hydrolysis of 5-nucleotides into their corresponding nucleosides [1].</p>Cor e Forma:Solid1'-Hydroxy bufuralol
CAS:<p>1'-Hydroxy bufuralol is a metabolite of bufuralol, an orally active β-adrenoceptor blocker used in the study of hypertension and cardiac arrhythmias.</p>Fórmula:C16H23NO3Cor e Forma:SolidPeso molecular:277.36L-Mevalonic acid
CAS:<p>L-Mevalonic acid, a cholesterol precursor, is studied in autoimmune, atherosclerosis, and Alzheimer's research.</p>Fórmula:C6H12O4Pureza:98%Cor e Forma:SolidPeso molecular:148.16UDP-α-D-Glucose sodium hydrate
<p>UDP-α-D-Glucose sodium hydrate is an endogenous metabolite and a pyrimidine nucleotide sugar, involved in glycosylation reactions during metabolic</p>Fórmula:C15H24N2Na2O18P2Cor e Forma:SolidPeso molecular:628.287-hydroxy Coumarin sulfate (potassium salt)
CAS:<p>7-hydroxy Coumarin sulfate, a phase II coumarin metabolite, aids as an internal standard for GC/LC-MS metabolic analyses.</p>Fórmula:C9H5KO6SCor e Forma:SolidPeso molecular:280.3Equilenin
CAS:<p>Equilenin (E 400) is a natural estrogen that is an endocrine disruptor and has been used in breast cancer research.</p>Fórmula:C18H18O2Pureza:99.4%Cor e Forma:SolidPeso molecular:266.33FITC-GW3965
CAS:<p>FITC-GW3965: Fluorescent LXRβ agonist; FITC replaces trifluoromethyl in GW3965; used to probe LXRβ function.</p>Fórmula:C59H56N4O9SCor e Forma:SolidPeso molecular:997.16Arofylline
CAS:<p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>Fórmula:C14H13ClN4O2Pureza:98.19%Cor e Forma:SolidPeso molecular:304.73FXR antagonist 2
CAS:<p>Compound A-26, a diarylamide FXR blocker, may aid hyperlipidemia and diabetes type 2 research.</p>Fórmula:C22H26Cl2N2O2Cor e Forma:SolidPeso molecular:421.361-Palmitoyl Lysophosphatidic Acid
CAS:<p>1-Palmitoyl Lysophosphatidic Acid boosts antibiotics against P. aeruginosa by binding Ca2+ and Mg2+.</p>Fórmula:C19H39O7PPureza:98%Cor e Forma:SolidPeso molecular:410.48Isoglycycoumarin
CAS:<p>Isoglycycoumarin, a flavonoid derived from the roots of Glycyrrhiza uralensis, serves as a highly selective probe for human cytochrome P450 2A6.</p>Fórmula:C21H20O6Pureza:98%Cor e Forma:SolidPeso molecular:368.38BIRM 271
CAS:<p>BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.</p>Fórmula:C21H25N3OPureza:99.64%Cor e Forma:SoildPeso molecular:335.44(S)-ICMT-IN-3
<p>'(S)-ICMT-IN-3 (compound ent 1-27) is an ICMT inhibitor with an IC50 value of 0.23 μM [1].'</p>Cor e Forma:Odour SolidEstriol 3-glucuronide
CAS:<p>Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].</p>Fórmula:C24H32O9Cor e Forma:SolidPeso molecular:464.511Previtamin D3
CAS:<p>Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).</p>Fórmula:C27H44OCor e Forma:SolidPeso molecular:384.648Seocalcitol
CAS:<p>Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).</p>Fórmula:C30H46O3Pureza:98%Cor e Forma:SolidPeso molecular:454.6810-Formyldihydrofolate
CAS:<p>10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase.</p>Fórmula:C20H21N7O7Cor e Forma:SolidPeso molecular:471.43Vitamin D4
CAS:<p>Vitamin D4 is the active Vitamin D analog.</p>Fórmula:C28H46OPureza:98%Cor e Forma:SolidPeso molecular:398.66Cystocholic acid
CAS:<p>Cystocholic acid is a metabolite of bile acids, possessing antimicrobial potential.</p>Fórmula:C27H45NO7Cor e Forma:SolidPeso molecular:495.65sn-Glycerol 3-phosphate lithium
<p>Lithium sn-glycerol 3-phosphate made by converting dihydroxyacetone phosphate via NADH from glycolysis.</p>Cor e Forma:SolidRabbit Factor Xa
<p>RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.</p>Cor e Forma:Odour SolidM3/PDE4 modulator-1
<p>M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.</p>Fórmula:C38H41Cl2N3O8SCor e Forma:SolidPeso molecular:770.72Xanthine oxidase-IN-9
CAS:<p>Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1].</p>Fórmula:C38H50O20Cor e Forma:SolidPeso molecular:826.79DSPE-PEG5000-MPG
<p>DSPE-PEG5000-MPG is a PEG compound composed of DSPE and a peptide carrier (MPG). MPG is derived from the nuclear localization sequence (NLS) of the SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. This compound effectively delivers short oligonucleotides into cells independently of the endosomal pathway.</p>Cor e Forma:Odour SolidMDNI-caged-L-glutamate
CAS:<p>MDNI-glu: photosensitive, bio-inert L-glutamate derivative with enhanced light utilization.</p>Fórmula:C14H16N4O8Cor e Forma:SolidPeso molecular:368.3021,2-POPS sodium salt
CAS:<p>1,2-POPS sodium salt is a lipid that can be used to synthesize artificial lipid membranes.</p>Fórmula:C40H75NNaO10PCor e Forma:SolidPeso molecular:783.9913,14-dehydro-15-cyclohexyl Carbaprostacyclin
CAS:<p>13,14-dehydro-15-cyclohexyl Carbaprostacyclin, a stable PGI2 analog, impedes ADP-induced platelet aggregation; ED50 ~40 nM in PRP, 77 nM in washed platelets.</p>Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.467PKM2-IN-4
<p>Compound 5C, referred to as Pkm2-in-4, is a selective PKM2 inhibitor (IC50 = 0.35 µM) that modulates pyruvate-dependent respiration and promotes mitochondrial</p>Fórmula:C15H17BrClNO3SeCor e Forma:SolidPeso molecular:453.62GlcNAc kinase (EcNagK)
<p>GlcNAc kinase (EcNagK), ATP-dependent, phosphorylates C-6 hydroxyl on GlcNAc, producing GlcNAc-6-P.</p>Cor e Forma:Solid(±)13-HODE cholesteryl ester
CAS:<p>(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.</p>Fórmula:C45H76O3Cor e Forma:SolidPeso molecular:665.19AzNue5Ac
CAS:<p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>Fórmula:C11H18N4O8Pureza:≥98%Cor e Forma:SolidPeso molecular:334.28SB-435495 ditartrate
CAS:<p>SB-435495 ditartrate is a potent, selective, reversible, non-covalent, and orally active inhibitor of Lp-PLA2, demonstrating an IC50 value of 0.06 nM [1] [3].</p>Fórmula:C46H52F4N6O14SCor e Forma:SolidPeso molecular:1020.99Hippadine
CAS:<p>Hippadine is isolated from Crinum bulbs and has reproductive effect.</p>Fórmula:C16H9NO3Cor e Forma:SolidPeso molecular:263.255-Aminolevulinic acid
CAS:<p>5-Aminolevulinic acid: heme synthesis intermediate, photosensitizer, antineoplastic, prodrug, treats actinic keratosis with blue light.</p>Fórmula:C5H9NO3Pureza:98%Cor e Forma:SolidPeso molecular:131.13Kazusamycin A
CAS:<p>Kazusamycin A is a new antitumor antibiotic.</p>Fórmula:C33H48O7Cor e Forma:SolidPeso molecular:556.74(R)-Mephenytoin
CAS:<p>(R)-Mephenytoin ((–)-Mephenytoin) is the the R-enantiomer of Mephenytoin which is an anticonvulsant agent.</p>Fórmula:C12H14N2O2Pureza:99.95%Cor e Forma:SolidPeso molecular:218.25α-Glucosidase-IN-80
<p>α-Glucosidase-IN-80 (Compound 10n) is a potent competitive inhibitor of α-glucosidase, with an IC50 of 48.4 μM. It exhibits favorable pharmacokinetic properties and toxicity profiles, making it suitable for research in diabetes-related conditions.</p>Fórmula:C24H24N8OS2Cor e Forma:SolidPeso molecular:504.63BDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Cor e Forma:Odour Solid3α-Hydroxysteroid dehydrogenase
CAS:<p>3α-Hydroxysteroid dehydrogenase (3α-HSD), encoded by the AKR1C4 gene, is responsible for catalyzing the transformation of 3-ketosteroids into 3α-hydroxy</p>Cor e Forma:SolidLaprafylline
CAS:<p>Laprafylline: Xanthine derivative, blocks bronchoconstriction & tumor growth, competes with serotonin, resists histamine at high levels.</p>Fórmula:C29H36N6O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:500.64tetranor-PGEM
CAS:<p>Tetranor-PGEM, the primary urinary byproduct of PGE1 and PGE2, marks PGE2 production; humans excrete 7-40 μg daily.</p>Fórmula:C16H24O7Cor e Forma:SolidPeso molecular:328.361NU223612
CAS:<p>"NU223612 is a potent IDO1-degrading PROTAC with Kd 640 nM, binds CRBN at 290 nM, and crosses the BBB."</p>Fórmula:C49H55FN6O9Cor e Forma:SolidPeso molecular:890.9910 FTHF disodium
CAS:<p>10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate that is involved in the synthesis of purine compounds.</p>Fórmula:C20H21N7Na2O7Cor e Forma:SolidPeso molecular:517.4Nampt-IN-10 trihydrochloride
<p>Nampt-IN-10 trihydrochloride, a NAMPT inhibitor, is effective on A2780 & CORL23 cells (IC50: 5/19 nM); potential ADC payload.</p>Fórmula:C27H31Cl3FN5O2Cor e Forma:SolidPeso molecular:582.9219,20-Epoxycytochalasin D
CAS:<p>Fungal metabolite 19,20-Epoxycytochalasin D from Nemania sp. kills P. falciparum; non-toxic to Vero, toxic to BT-549, LLC-PK11, P388 cells.</p>Fórmula:C30H37NO7Cor e Forma:SolidPeso molecular:523.626PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Fórmula:C23H28FN7O3Cor e Forma:SolidPeso molecular:469.51Monoglyceride lipase
CAS:<p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>Cor e Forma:Solidα-Glucosidase-IN-72
<p>α-Glucosidase-IN-72 (compound 5i), a 2,4-dichloro-N-phenylacetamide derivative, functions as an α-glucosidase inhibitor with an inhibitory concentration (IC 50) of 6 μM. Notably, it does not adhere to Lipinski's "rule of five" and is not a cancer inducer.</p>Fórmula:C37H26Cl2N4O9Cor e Forma:SolidPeso molecular:741.53PP5-IN-2
<p>PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.</p>Fórmula:C16H15NO4Cor e Forma:SolidPeso molecular:285.29Penicillinase
CAS:<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>Cor e Forma:SolidC-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS:<p>C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.</p>Cor e Forma:SolidIDO1-IN-12
CAS:<p>IDO1-IN-12 is a potent and orally available IDO1 inhibitor.</p>Fórmula:C21H19F3N2O2Cor e Forma:SolidPeso molecular:388.39α-Glucosidase-IN-73
<p>α-Glucosidase-IN-73 (compound 16b), an α-Glucosidase inhibitor, exhibits an IC 50 value of 0.158 μM and possesses the ability to activate PPAR γ. This compound is applicable in studies focusing on anti-diabetic and anti-inflammatory treatments.</p>Fórmula:C24H21N3O2SCor e Forma:SolidPeso molecular:415.51
