Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8595 produtos de "Metabolismo"
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sEH inhibitor-17
CAS:<p>sEH inhibitor-17 (compound 4f) is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 value of 2.94 nM. This compound exhibits anti-inflammatory properties.</p>Fórmula:C18H21F3N2O4SCor e Forma:SolidPeso molecular:418.43Betrixaban
CAS:<p>Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.</p>Fórmula:C23H22ClN5O3Pureza:99.33%Cor e Forma:SolidPeso molecular:451.91MDI-2268
CAS:<p>MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.</p>Fórmula:C10H10F3N3O3Cor e Forma:SolidPeso molecular:277.20PTC-510 TFA salt
CAS:<p>PTC-510 TFA salt inhibits hypoxia-induced VEGF expression.</p>Fórmula:C26H26BrN3O2SPureza:98%Cor e Forma:SolidPeso molecular:524.48Nitrophenide
CAS:<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Fórmula:C12H8N2O4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:308.33PPM1A-IN-1
CAS:<p>PPM1A-IN-1 (Compound IV-4) is an inhibitor of the PP2C Ser/Thr protein phosphatase Mg2+/Mn2+-dependent 1A. It exhibits antibacterial activity against Mycobacterium tuberculosis.</p>Fórmula:C16H15BrFNO2Cor e Forma:SolidPeso molecular:352.2(+)-Xylariamide A
CAS:<p>(+)-Xylariamide A is a probe used for mycobacterial and fungal carbonic anhydrase.</p>Fórmula:C14H14ClNO6Cor e Forma:SolidPeso molecular:327.72JZP-MA-11
CAS:<p>"JZP-MA-11 is a PET ligand that selectively targets ABHD6, inhibits with 126 nM IC50, and crosses the BBB for preclinical brain studies."</p>Fórmula:C15H17FN4O2SCor e Forma:SolidPeso molecular:336.38Thevetin A
CAS:<p>Thevetin A is a useful organic compound for research related to life sciences. The catalog number is T124930 and the CAS number is 37933-66-7.</p>Fórmula:C42H64O19Cor e Forma:SolidPeso molecular:872.955Ranelic acid
CAS:<p>Ranelic acid chelates metals; its strontium salt treats osteoporosis, boosting bone density.</p>Fórmula:C12H10N2O8SPureza:98%Cor e Forma:SolidPeso molecular:342.281,2-Dibehenoyl-sn-glycero-3-phosphocholine
CAS:<p>1,2-Dibehenoyl-sn-glycero-3-phosphocholine (DBPC), a phospholipid integral to cell membranes, facilitates the formation of micelles, liposomes, and various artificial membranes [1].</p>Fórmula:C48H80NO8PCor e Forma:SolidPeso molecular:830.141Tolrestat
CAS:<p>Tolrestat (AY-27773) is a potent inhibitor of aldose reductase (IC50 = 35 nM).</p>Fórmula:C16H14F3NO3SPureza:98.89% - >99.99%Cor e Forma:SolidPeso molecular:357.35Tesaglitazar
CAS:<p>Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα</p>Fórmula:C20H24O7SPureza:99.95%Cor e Forma:SolidPeso molecular:408.47Calcipotriol monohydrate
CAS:<p>Calcipotriol monohydrate, a Vitamin D3 analog, binds well to the vitamin D receptor, used in psoriasis research.</p>Fórmula:C27H42O4Pureza:99.95%Cor e Forma:SolidPeso molecular:430.621-Decanesulfonic acid
CAS:<p>1-Decanesulfonic acid (Decane-1-sulfonic acid) is a potential amyloid beta peptide (Aβ40) inhibitor, useful for studying cardiovascular diseases.</p>Fórmula:C10H22O3SCor e Forma:SolidPeso molecular:222.35L-m-Tyrosine
CAS:<p>L-m-Tyrosine (3-Hydroxy-L-Phenylalanine) is a non-natural amino acid.</p>Fórmula:C9H11NO3Pureza:99.8%Cor e Forma:SolidPeso molecular:181.19BIBB 515
CAS:<p>BIBB 515 inhibits OSC, reducing cholesterol in hamsters by up to 25% with specific dosing.</p>Fórmula:C22H21ClN2O2Pureza:99.68%Cor e Forma:SolidPeso molecular:380.873-Phenylbutyric acid
CAS:<p>3-Phenylbutyric acid, from compost soil, metabolizes via benzene and side-chain oxidation.</p>Fórmula:C10H12O2Pureza:98.26%Cor e Forma:SolidPeso molecular:164.2PCI-27483
CAS:<p>PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis.</p>Fórmula:C26H24N6O9SPureza:98.55%Cor e Forma:SolidPeso molecular:596.57E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.464-POBN
CAS:<p>4-POBN (Myeloperoxidase Inhibitor 1) is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM).</p>Fórmula:C7H9N3OPureza:99.60%Cor e Forma:White Crystalline PowderPeso molecular:151.17PF-05175157
CAS:<p>PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2,</p>Fórmula:C23H27N5O2Pureza:98% - 99.92%Cor e Forma:SolidPeso molecular:405.49SCH-42354
CAS:<p>SCH-42354: potent oral NEP inhibitor, activates ANP & leu-enkephalin, has anti-hypertensive properties, IC50s of 8.3 & 10.0 nM.</p>Fórmula:C16H23NO3S2Cor e Forma:SolidPeso molecular:341.49Dehydronitrosonisoldipine
CAS:<p>Dehydronitrosonisoldipine blocks SARM1, slows axon decay & cADPR synthesis; useful in neurodegeneration research.</p>Fórmula:C20H22N2O5Pureza:99.68%Cor e Forma:SolidPeso molecular:370.4ICI 211965
CAS:<p>ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).</p>Fórmula:C24H23NO2SPureza:98%Cor e Forma:SolidPeso molecular:389.51Rev 6207
CAS:<p>Rev 6207 is a non-sulfhydryl ACE-inhibitor.</p>Fórmula:C21H31N3O5Cor e Forma:SolidPeso molecular:405.49Factor VII-IN-1
CAS:<p>Factor VII-IN-1 (example 43) is an effective Factor VII (FVII) inhibitor (IC50=1.1 μM) with anticoagulant properties.</p>Fórmula:C15H10BrNO3Pureza:99.19%Cor e Forma:SolidPeso molecular:332.15hCA I-IN-1
CAS:<p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57Ornithine-α-ketoglutarate
CAS:<p>Ornithine-α-ketoglutarate (L-Ornithine-α-ketoglutarate) is a salt formed of 2 molecules of ornithine and 1 alpha-ketoglutarate.</p>Fórmula:C10H18N2O7Pureza:≥98%Cor e Forma:White PowderPeso molecular:278.26Afegostat D-Tartrate
CAS:<p>Afegostat D-Tartrate: pharmacological chaperone, reversibly binds acid-β-glucosidase in ER with high affinity.</p>Fórmula:C10H19NO9Pureza:98%Cor e Forma:SolidPeso molecular:297.262614W94
CAS:2614W94 is a selective inhibitor of MAO-A with IC50 of 5 nM and Ki of 1.6 nM.Fórmula:C15H11F3O4SPureza:99.6%Cor e Forma:SolidPeso molecular:344.31Icomucret
CAS:<p>Icomucret can be used for the Treatment of Dry Eye.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.4714(S)-HDHA
CAS:<p>DHA is an ω-3 important for development and therapy for inflammation and cancer; its derivative, 14(S)-HDHA, aids in reducing inflammation.</p>Fórmula:C22H32O3Cor e Forma:SolidPeso molecular:344.49PF-07208254
CAS:<p>PF-07208254, a potent BDK inhibitor, enhances cardiometabolic endpoints in mice [1].</p>Fórmula:C7H2ClFO2S2Pureza:98%Cor e Forma:SolidPeso molecular:236.67ML-262
CAS:<p>ML-262 is an effective inhibitor of hepatic lipid droplet formation and is used in studies of non-alcoholic fatty liver disease.</p>Fórmula:C27H32N2O4SCor e Forma:SolidPeso molecular:480.62Razaxaban hydrochloride
CAS:<p>Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.</p>Fórmula:C24H21ClF4N8O2Pureza:98%Cor e Forma:SolidPeso molecular:564.92RORγt inverse agonist 30
CAS:<p>RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist (IC50: 46 nM).</p>Fórmula:C24H31N3O3SCor e Forma:SolidPeso molecular:441.59L-693612 HCl
CAS:<p>L-693612 HCl is an inhibitor of carbonic anhydrase.</p>Fórmula:C14H25ClN2O5S3Pureza:98%Cor e Forma:SolidPeso molecular:433.0111β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Fórmula:C21H19ClN4OCor e Forma:SolidPeso molecular:378.86Desfluoro-atorvastatin
CAS:<p>Desfluoro-atorvastatin is an impurity of atorvastatin, an oral HMG-CoA reductase inhibitor that lowers blood lipids.</p>Fórmula:C33H36N2O5Pureza:98%Cor e Forma:SolidPeso molecular:540.65BMS-593214
CAS:<p>BMS-593214 is an inhibitor of active site-directed factor VIIa and a non-competitive inhibitor of the VIIa-activated substrate FX.</p>Fórmula:C31H27N3O4Pureza:96.63% - 98.04%Cor e Forma:SolidPeso molecular:505.56KM04416
CAS:<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Fórmula:C12H11NO3SPureza:99.88%Cor e Forma:SolidPeso molecular:249.29(±)-γ-Tocopherol
CAS:<p>(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.</p>Fórmula:C28H48O2Cor e Forma:SolidPeso molecular:416.68L-5-BromoTryptophan
CAS:<p>L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S.</p>Fórmula:C11H11BrN2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:283.12CL 242817
CAS:<p>CL 242817 is an inhibitor of angiotensin converting enzyme (ACE).</p>Fórmula:C18H21NO5SCor e Forma:SolidPeso molecular:363.4311β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Fórmula:C13H9F3N2OCor e Forma:SolidPeso molecular:266.22CFG920
CAS:<p>CFG920 is an oral CYP17 inhibitor that may reduce androgen production and inhibit growth of androgen-dependent tumors.</p>Fórmula:C14H13ClN4OCor e Forma:SolidPeso molecular:288.73Otamixaban
CAS:<p>Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.</p>Fórmula:C25H26N4O4Pureza:98.08%Cor e Forma:SolidPeso molecular:446.5hCAIX/XII-IN-2
CAS:<p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).</p>Fórmula:C19H14N2O4Cor e Forma:SolidPeso molecular:334.33LY 221068
CAS:<p>LY 221068 is a potent antioxidant with anti-inflammatory activity.</p>Fórmula:C20H30N2O2SPureza:98%Cor e Forma:SolidPeso molecular:362.53Quinapril-d5
CAS:<p>Quinapril-d5: An internal standard for quinapril quantification via GC/LC-MS; a prodrug ACE inhibitor for hypertension and heart failure.</p>Fórmula:C25H25D5N2O5Cor e Forma:SolidPeso molecular:443.55BMS-351
CAS:<p>BMS-351: potent, selective CYP17A1 inhibitor, promising for prostate cancer, minimal side effects.</p>Fórmula:C15H12F3N3Cor e Forma:SolidPeso molecular:291.27Glucocerebrosidase-IN-1
CAS:<p>Glucocerebrosidase-IN-1 inhibits GCase with IC50 of 29.3 μM, Ki 18.5 μM, useful for Gaucher's and Parkinson's research.</p>Fórmula:C13H27NO3Cor e Forma:SolidPeso molecular:245.36Methazolamide-d6
CAS:<p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>Fórmula:C5H2D6N4O3S2Cor e Forma:SolidPeso molecular:242.31GNF362
CAS:<p>GNF362 is an ITPKB inhibitor that inhibits Itpka and Itpkc and reverses the migratory stimulatory effect of ITPKA overexpression.</p>Fórmula:C22H21F3N6Pureza:99.63%Cor e Forma:SolidPeso molecular:426.44ARN19874
CAS:<p>ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor. With an IC50 of ~34 μM[1].</p>Fórmula:C19H14N4O4SPureza:98%Cor e Forma:SolidPeso molecular:394.4PDE5-IN-5
CAS:<p>PDE5-IN-5 is a selective inhibitor of phosphodiesterase 5 (PDE5) (IC50: 2.0 nM).</p>Fórmula:C23H20BrN3O4Cor e Forma:SolidPeso molecular:482.33LEO 39652
CAS:<p>LEO 39652: Dual-soft PDE4 inhibitor, IC50s: PDE4A/B: 1.2 nM, PDE4C: 3.0 nM, PDE4D: 3.8 nM; TNF-α IC50: 6.0 nM; for Atopic dermatitis research.</p>Fórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.453-Oxo-hop-22(29)-ene
CAS:<p>3-Oxo-hop-22(29)-ene inhibits yeast α-glucosidase, moderately affects T. cruzi and L. mexicana, and has slight anti-inflammatory activity.</p>Fórmula:C30H48OCor e Forma:SolidPeso molecular:424.7RO6806051
CAS:<p>RO6806051 (compound 12) is a potent dual inhibitor of fatty acid binding proteins 4 and 5 (FABP4 and FABP5), exhibiting excellent selectivity and absorption, distribution, metabolism, and excretion (eADME) properties.</p>Fórmula:C21H19ClN6Cor e Forma:SolidPeso molecular:390.87Letimide HCl
CAS:<p>Letimide HCl is an analgesic agent.</p>Fórmula:C14H19ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:298.77Vorozole
CAS:<p>Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in</p>Fórmula:C16H13ClN6Pureza:99.65% - 99.94%Cor e Forma:SolidPeso molecular:324.77Lombricine
CAS:<p>Lombricine, as a phosphodiester of 2-guanidinoethanol and D-serine in structure, is a phosphagen that is unique to earthworms.</p>Fórmula:C6H15N4O6PCor e Forma:SolidPeso molecular:270.18XEN103
CAS:<p>XEN103 is a potent and selective Stearoyl-CoA Desaturase-1 inhibitor.</p>Fórmula:C22H23F4N5O2Cor e Forma:SolidPeso molecular:465.44BBMP
CAS:<p>BBMP is an inhibitor of mitochondrial permeability transition pore.</p>Fórmula:C12H11BrN2O3SCor e Forma:SolidPeso molecular:343.2SCD1 inhibitor-1
CAS:SCD1 inhibitor-1 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase-1 (SCD1).Fórmula:C21H23N3NaO3S2Pureza:98%Cor e Forma:SolidPeso molecular:452.54FABP4/5-IN-5
CAS:<p>FABP4/5-IN-5 (compound D9) serves as a potent inhibitor of both FABP 4 and FABP 5, demonstrating IC50 values of 4.68 μM and 10.72 μM, respectively. It is notably effective in addressing metabolic disorders such as diabetes mellitus [1].</p>Fórmula:C23H14ClF2NO4SCor e Forma:SolidPeso molecular:473.88A-1293201
CAS:<p>A-1293201 is a potent and selective NAMPT inhibitor.</p>Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43Cefetrizole
CAS:<p>Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).</p>Fórmula:C16H15N5O4S3Pureza:98%Cor e Forma:SolidPeso molecular:437.52Dopropidil
CAS:<p>Dopropidil: anti-angina calcium regulator with anti-ischemic properties in animal models.</p>Fórmula:C20H35NO2Pureza:98%Cor e Forma:SolidPeso molecular:321.5SA57
CAS:<p>SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).</p>Fórmula:C17H23ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:338.83FSG67
CAS:<p>FSG67 is an inhibitor of glycerol 3-phosphate acyltransferase (IC 50 =24 μM) [1].</p>Fórmula:C16H25NO4SPureza:99.76%Cor e Forma:SolidPeso molecular:327.44α-2,3-sialyltransferase-IN-1
CAS:<p>α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).</p>Fórmula:C28H45NO6Pureza:98% - 98%Cor e Forma:SolidPeso molecular:491.66MitoPBN
CAS:<p>MitoPBN: mitochondria-targeted antioxidant, inhibits UCP1-3 at 250 nM, traps hydroxyl & carbon radicals, prevents lipid peroxidation.</p>Fórmula:C33H37BrNO2PCor e Forma:SolidPeso molecular:590.542hCA I-IN-2
CAS:<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44Teglarinad chloride
CAS:<p>Teglarinad chloride (GMX-1777 chloride) is an inhibitor of NAMPT with antitumor activity that acts by interfering with DNA repair and inhibiting angiogenesis.</p>Fórmula:C30H43Cl2N5O8Pureza:98.09%Cor e Forma:SolidPeso molecular:672.6Cholesteryl Palmitoleate
CAS:<p>Cholesteryl palmitoleate, a cholesterol ester, exhibits elevated plasma levels in ApoE-/- mice following exposure to cigarette smoke and in pediatric patients diagnosed with biliary atresia. It serves as a standard for identifying cholesterol esters in human meibomian gland secretions.</p>Fórmula:C43H74O2Cor e Forma:SolidPeso molecular:623.1FKGK11
CAS:<p>FKGK11 is a potent inhibitor of GVIA iPLA2.</p>Fórmula:C13H13F5OPureza:98%Cor e Forma:SolidPeso molecular:280.23OL-135
CAS:<p>OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.</p>Fórmula:C21H22N2O2Cor e Forma:SolidPeso molecular:334.41RORγt modulator 3
CAS:<p>RORγt modulator 3 is a modulator of retinol-related orphan receptor γt (RORγt) and can be used to study RORγt-mediated diseases such as pain, COPD, inflammation</p>Fórmula:C25H25ClFN3O4SCor e Forma:SolidPeso molecular:518Pimobendan hydrochloride
CAS:<p>Pimobendan hydrochloride is a selective inhibitor of PDE3 (IC50: 0.32 μM).</p>Fórmula:C19H19ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:370.83Zidovudine glucuronide
CAS:<p>Zidovudine glucuronide: an NRTI antiretroviral for HIV/AIDS treatment; blocks HIV reverse transcriptase, stops viral DNA formation.</p>Fórmula:C16H21N5O10Cor e Forma:SolidPeso molecular:443.37M77976
CAS:<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Fórmula:C17H16N2O3Pureza:99.43%Cor e Forma:SolidPeso molecular:296.32Saterinone hydrochloride
CAS:<p>Saterinone hydrochloride is an inhibitor of phosphodiesterase III (PDE III).</p>Fórmula:C27H31ClN4O4Pureza:98%Cor e Forma:SolidPeso molecular:511.01POP-IN-2
CAS:<p>Compound 7k (POP-IN-2) is a potent POP inhibitor with Ki of 6 nM, useful in neurodegenerative and cancer studies.</p>Fórmula:C24H33BN2O5Cor e Forma:SolidPeso molecular:440.34Lp-PLA2-IN-4
CAS:<p>Lp-PLA2-IN-4, a potent inhibitor of Lp-PLA2/PAF-AH, may target Alzheimer's, atherosclerosis. (WO2021228159A1, Compound 38)</p>Fórmula:C23H18F5N3O4Cor e Forma:SolidPeso molecular:495.4Amastatin
CAS:<p>Amastatin is a non-toxic inhibitor of aminopeptidase A and leucine aminopeptidase, and its Ki for aminopeptidase A is 1 μM .</p>Fórmula:C21H38N4O8Pureza:98%Cor e Forma:SolidPeso molecular:474.55Flutolanil
CAS:<p>Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.</p>Fórmula:C17H16F3NO2Cor e Forma:SolidPeso molecular:323.31IDO1/TDO-IN-3
CAS:<p>IDO1/TDO-IN-3 inhibits IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM) with strong anti-tumor activity and low toxicity.</p>Fórmula:C16H6ClF2N3O2Cor e Forma:SolidPeso molecular:345.69Aminopeptidase-IN-1
CAS:<p>Aminopeptidase-IN-1: potent IRAP blocker, Ki 7.7 μM, useful for cognitive/memory disorder research.</p>Fórmula:C18H16N2O6Pureza:98.37%Cor e Forma:SolidPeso molecular:356.33HSL-IN-1
CAS:<p>HSL-IN-1 is an HSL inhibitor that significantly reduces the reactive metabolite load and reduces the release of free fatty acids from stored fat.</p>Fórmula:C19H13BClF3N2O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:436.58Albaconazole
CAS:<p>Albaconazole, a small fungal CYP51A1 inhibitor, treats fungal infections and some musculoskeletal disorders.</p>Fórmula:C20H16ClF2N5O2Pureza:99.27%Cor e Forma:SolidPeso molecular:431.82DHODH-IN-17
CAS:<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Fórmula:C12H9ClN2O2Pureza:99.41% - 99.52%Cor e Forma:SolidPeso molecular:248.67JZP-MA-13
<p>JZP-MA-13: selective α/β-hydrolase domain 6 inhibitor, IC 50 392 nM, doesn't inhibit MAGL/ABHD12/FAAH, used in PET imaging.</p>Fórmula:C14H15FN4O3SCor e Forma:SolidPeso molecular:338.36M8891
CAS:<p>M8891: Oral, reversible MetAP-2 inhibitor, brain-penetrant (IC50: 54nM; Ki: 4.33nM), hinders endothelial & tumor cell growth, antiangiogenic & antitumor.</p>Fórmula:C20H17F2N3O3Cor e Forma:SolidPeso molecular:385.36BRD9500
CAS:<p>BRD9500 is an oral PDE3 inhibitor, IC50: 10 nM (PDE3A), 27 nM (PDE3B); effective in SK-MEL-3 cancer model.</p>Fórmula:C15H18FN3O2Cor e Forma:SolidPeso molecular:291.32hCAXII-IN-3
CAS:<p>hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).</p>Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44GK187
CAS:<p>GK187 is a selective and potent Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor, used in the study of neurological disorders.</p>Fórmula:C14H15F5O2Cor e Forma:SolidPeso molecular:310.26GW844520
CAS:<p>GW844520 is a potent and selective inhibitor of the cytochrome bc1 complex of mitochondrial electron transport in P. falciparum.</p>Fórmula:C20H15ClF3NO3Cor e Forma:SolidPeso molecular:409.79PF-06471553
CAS:<p>PF-06471553 is an effective and selective inhibitor of monoacylglycerol acyltransferase 3 (IC50: 92 nM).</p>Fórmula:C23H25N5O4SPureza:98%Cor e Forma:SolidPeso molecular:467.54Oosponol
CAS:<p>Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.</p>Fórmula:C11H8O5Pureza:98%Cor e Forma:SolidPeso molecular:220.18Anti-hyperglycemic agent-1
CAS:<p>Anti-hyperglycemic agent 1 is a potent inhibitor of alpha-glucosidase (IC50: 0.53 μM). anti-Hyperglycemic agent 1 can be used to study diabetes.</p>Fórmula:C20H15BrN2O3Cor e Forma:SolidPeso molecular:411.25Hexazinone
CAS:<p>Hexazinone: a triazine herbicide blocks photosynthesis by binding to D-1 protein in photosystem II.</p>Fórmula:C12H20N4O2Pureza:99.99%Cor e Forma:SolidPeso molecular:252.31(Rac)-RK-682
CAS:<p>(Rac)-RK-682 racemate; inhibits PTP-1B, LMW-PTP, CDC-25B with IC50s: 8.6, 12.4, 0.7 µM respectively.</p>Fórmula:C21H36O5Cor e Forma:SolidPeso molecular:368.5117β-HSD10-IN-2
CAS:<p>17β-HSD10-IN-2 (compound 11), a benzothiazolylurea-based inhibitor, specifically targets 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), avoiding</p>Fórmula:C15H10ClN3O4SPureza:98%Cor e Forma:SolidPeso molecular:363.78JTV-519
CAS:<p>K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) by</p>Fórmula:C25H33ClN2O2SPureza:99.88%Cor e Forma:SolidPeso molecular:461.06Calcium glycerophosphate
CAS:<p>CaGP inhibits intestinal alkaline phosphatase F3; used for calcium and phosphorus in parenteral nutrition.</p>Fórmula:C3H7CaO6PPureza:99.84%Cor e Forma:SolidPeso molecular:210.142'-Ethyl Simvastatin
CAS:<p>2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.</p>Fórmula:C23H34O5Pureza:98%Cor e Forma:SolidPeso molecular:390.51DPC-423
CAS:<p>DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.</p>Fórmula:C25H21ClF4N4O3SPureza:98%Cor e Forma:SolidPeso molecular:568.97α-Glucosidase-IN-6
CAS:<p>α-Glucosidase-IN-6 is a competitive inhibitor of α-glucosidase (IC50: 5.69 μM) and exhibits potential for anti-diabetic studies.</p>Fórmula:C24H17ClF3NO3SCor e Forma:SolidPeso molecular:491.91T-1095A
CAS:<p>T-1095A, a T-1095 metabolite, inhibits SGLTs, lowers blood glucose, improves glucose intolerance in mice, and prevents neuropathy in diabetic rats.</p>Fórmula:C24H26O9Pureza:98%Cor e Forma:SolidPeso molecular:458.46LZWL02003
CAS:<p>LZWL02003, an anti-neuroinflammatory agent, demonstrates a protective effect on MPP+-induced neuronal damage and reduces ROS expression.</p>Fórmula:C18H18N2O2Pureza:98%Cor e Forma:SolidPeso molecular:294.35CDK2-IN-12
CAS:<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Fórmula:C20H17N9O2SCor e Forma:SolidPeso molecular:447.47Crilvastatin
CAS:<p>Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.</p>Fórmula:C14H23NO3Pureza:98.69% - 99.54%Cor e Forma:SolidPeso molecular:253.34Tenuazonic acid
CAS:<p>Tenuazonic acid, a nonhost-selective mycotoxin from Alternaria alternate, inhibits PSII by blocking electron transport at D1 protein.</p>Fórmula:C10H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:197.23Hydroxythiohomosildenafil
CAS:<p>Hydroxythiohomosildenafil, an analogue of sildenafil, is a phosphodiesterase-5 (PDE-5) inhibitor.</p>Fórmula:C23H32N6O4S2Pureza:99.45%Cor e Forma:SolidPeso molecular:520.67Tanogitran
CAS:<p>Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.</p>Fórmula:C25H31N7O3Pureza:98%Cor e Forma:SolidPeso molecular:477.56BMP-22
CAS:<p>BMP-22 selectively inhibits autotaxin (IC50=170 nM), blocks LPA production and MM1 cell invasion, and reduces lung metastases in mice at 0.5 mg/kg/day.</p>Fórmula:C22H39O3PCor e Forma:SolidPeso molecular:382.52SAHO
CAS:<p>SAHO is a methyl donor cleaved by SAM enzymes into adenosylhomocysteine and thioadenosine derivatives.</p>Fórmula:C14H20N6O6SCor e Forma:SolidPeso molecular:400.41D-Erythro-dihydrosphingosine
CAS:<p>D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) inhibits arachidonic acid release and cPLA2α activity.</p>Fórmula:C18H39NO2Pureza:99.50% - 99.88%Cor e Forma:SolidPeso molecular:301.51Fexarine
CAS:<p>Fexarine is a potent, selective agonist of farnesoid X receptor.</p>Fórmula:C31H31NO5Cor e Forma:SolidPeso molecular:497.58Fluasterone
CAS:<p>Fluasterone, an NF-κB activation inhibitor, is used potentially for the treatment of metabolic syndrome.</p>Fórmula:C19H27FOPureza:98%Cor e Forma:SolidPeso molecular:290.42KT109
CAS:<p>KT109 is a DAGLβ inhibitor (IC50=42nM), lessens LPS allodynia in mice without tolerance, and has no major side effects.</p>Fórmula:C27H26N4OPureza:98%Cor e Forma:SolidPeso molecular:422.52Diapocynin
CAS:<p>Diapocynin (Dehydrodiacetovanillone), a dimer of Apocynin, acts as an orally administered inhibitor of NADPH oxidase.</p>Fórmula:C18H18O6Cor e Forma:SolidPeso molecular:330.33KD-027
CAS:<p>KD-027 is a novel and long-acting PDE5A(phosphodiesterase 5A) inhibitor with potential antihypertensive activity.</p>Fórmula:C25H35N7O6SPureza:99.55%Cor e Forma:SolidPeso molecular:561.65Tebuconazole-d9
CAS:<p>Tebuconazole-d9 is a GC/LC-MS standard for quantifying the triazole fungicide tebuconazole, affecting seed/foliar fungi and androgen receptors.</p>Fórmula:C16H13ClD9N3OCor e Forma:SolidPeso molecular:316.87HFI-437
CAS:<p>HFI-437 is a potent, non-peptidic, insulin-regulated aminopeptidase (IRAP) inhibitor with a K i of 20 nM and functions as a cognitive enhancer [1].</p>Fórmula:C23H20N2O5Cor e Forma:SolidPeso molecular:404.42RO-28-1675
CAS:<p>RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.</p>Fórmula:C18H22N2O3S2Pureza:98.13%Cor e Forma:SolidPeso molecular:378.51AGI-026
CAS:<p>AGI-026 (AGI-12026) is a novel and potent dual inhibitor of the mutant isocitrate dehydrogenase mIDH1/2 blood-brain barrier, reduce d-2-hydroxyglutarate (2-HG).</p>Fórmula:C18H15F6N7Pureza:99.79% - 99.86%Cor e Forma:SolidPeso molecular:443.35HZ52
CAS:<p>HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.</p>Fórmula:C24H26ClN3O2SCor e Forma:SolidPeso molecular:456ALDH1A1-IN-3
CAS:<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Fórmula:C31H36F3N5O4Cor e Forma:SolidPeso molecular:599.64PDE-9 inhibitor
CAS:<p>PDE-9 inhibitor is used for treatment neurodegenerative diseases.</p>Fórmula:C22H27N5O2Pureza:98%Cor e Forma:SolidPeso molecular:393.481-Methyluric acid
CAS:<p>1-Methyluric acid (1-Methylurate) acts on the bladder mucosa and increases the levels of insulin, triglycerides, cholesterol, and blood glucose.</p>Fórmula:C6H6N4O3Pureza:98.05%Cor e Forma:SolidPeso molecular:182.14Arcapillin
CAS:<p>Arcapillin, an anticancer agent, induces apoptosis mediated at least in part by the ERS pathway and inhibits hepatoma tumor growth.</p>Fórmula:C18H16O8Cor e Forma:SolidPeso molecular:360.31NSC117079
CAS:<p>NSC117079 is a novel PHLPP1/2 (Pleckstrin homology domain and leucine rich repeat protein phosphatase) inhibitor that activates neuronal AKT .</p>Fórmula:C20H15N3O7S2Pureza:98.11%Cor e Forma:SolidPeso molecular:473.48PAT-048
CAS:<p>PAT-048 is an effective and selective autotaxin inhibitor.</p>Fórmula:C22H18ClF2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:461.91L-Canaline
CAS:<p>L-Canaline is a nonprotein amino acid with IC50 of 297 nM against malaria, anticancer properties, and blocks ornithine aminotransferase.</p>Fórmula:C4H10N2O3Pureza:98%Cor e Forma:SolidPeso molecular:134.13DU717
CAS:<p>DU717 is an antihypertensive agent.</p>Fórmula:C12H15ClN4O2SPureza:99.64%Cor e Forma:SolidPeso molecular:314.791E7-03
CAS:<p>1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).</p>Fórmula:C28H29N3O6Cor e Forma:SolidPeso molecular:503.55ATX inhibitor 20
CAS:<p>ATX inhibitor 20 is a potent inhibitor of ATX (IC50: 2.3 nM).</p>Fórmula:C31H34FN5O3Cor e Forma:SolidPeso molecular:543.63ML299
CAS:<p>ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively).</p>Fórmula:C23H26BrFN4O2Pureza:98%Cor e Forma:SolidPeso molecular:489.38Leniquinsin
CAS:<p>Leniquinsin is an antihypertensive compound. It is a phosphodiesterase inhibitor and a potent vasodilator.</p>Fórmula:C20H20N2O4Pureza:98%Cor e Forma:SolidPeso molecular:352.38Z-321
CAS:<p>Z-321 is an inhibitor of prolyl endopeptidase.</p>Fórmula:C19H24N2O2SPureza:98%Cor e Forma:SolidPeso molecular:344.47EN40
CAS:<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Fórmula:C13H15NO2Cor e Forma:SolidPeso molecular:217.26SWE101
CAS:<p>SWE101 is a potent human and rat soluble epoxide hydrolase (sEH)-P inhibitor(IC50s of 4 μM and 2.8 μM, respectively).</p>Fórmula:C19H15Cl2NO3Pureza:98%Cor e Forma:SolidPeso molecular:376.23FABP-IN-2
CAS:<p>FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.</p>Fórmula:C25H21ClN2O3Cor e Forma:SolidPeso molecular:432.9K134
CAS:<p>K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.</p>Fórmula:C22H29N3O4Pureza:98%Cor e Forma:SolidPeso molecular:399.48Utibapril
CAS:<p>Utibapril is an inhibitor of angiotensin-converting enzyme (ACE) with antihypertensive activities.</p>Fórmula:C22H31N3O5SPureza:98%Cor e Forma:SolidPeso molecular:449.56MY33-3 hydrochloride
CAS:<p>MY33-3 HCl: Inhibits RPTPβ/ζ (IC50~0.1μM), PTP-1B (IC50~0.7μM), curbs alcohol intake, fights neuroinflammation and memory issues.</p>Fórmula:C16H14ClF6NS2Cor e Forma:SolidPeso molecular:433.86ZM223
CAS:<p>ZM223 is an inhibitor of NEDD8 activating enzyme (NAE).</p>Fórmula:C23H17F3N4O2S2Pureza:99.73%Cor e Forma:SolidPeso molecular:502.53PSN-GK1
CAS:<p>PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).</p>Fórmula:C20H23FN2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:438.54IDO-IN-3
CAS:<p>IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 290 nM).</p>Fórmula:C11H12BrFN6O2Cor e Forma:SolidPeso molecular:359.15Gcase activator 3
CAS:<p>Gcase activator 3 is a glucocerebrosidase (GCase) activator that enhances GBA1 mutant fibroblast lysosomal GCase activity.</p>Fórmula:C23H20N4O2Pureza:99.08%Cor e Forma:SolidPeso molecular:384.43ENPP1 inhibitor 43
CAS:<p>ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.</p>Fórmula:C16H18N6O3SCor e Forma:SolidPeso molecular:374.42OSMI-3
CAS:<p>OSMI-3 is a potent and cell-permeable inhibitor of O-GlcNAc transferase (OGT) for the study of cancer and cardiovascular disease.</p>Fórmula:C32H35N3O9S2Pureza:99.03% - 99.08%Cor e Forma:SolidPeso molecular:669.77IDO/TDO-IN-1
CAS:<p>IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).</p>Fórmula:C25H24FN5Pureza:98%Cor e Forma:SolidPeso molecular:413.49trans-Ned 19
CAS:<p>trans-Ned 19 blocks NAADP and TPC, hindering calcium signaling and aorta relaxation at low histamine levels.</p>Fórmula:C30H31FN4O3Pureza:98%Cor e Forma:SolidPeso molecular:514.59PDE4-IN-11
CAS:<p>PDE4-IN-11: Potent PDE4 inhibitor with strong bronchodilatory and anti-inflammatory effects for airway disease research.</p>Fórmula:C21H19FN2O2Cor e Forma:SolidPeso molecular:350.39Xanthine oxidase-IN-4
CAS:<p>Xanthine oxidase-IN-4: an oral XO inhibitor with 0.039 μM IC50, useful for hyperuricemia/gout research.</p>Fórmula:C15H13N5O2Cor e Forma:SolidPeso molecular:295.3PRRSV/CD163-IN-1
CAS:<p>PRRSV/CD163-IN-1 blocks PRRSV GP2a/GP4 and CD163-SRCR5, aiding PRRS research.</p>Fórmula:C25H24FN5O5S2Cor e Forma:SolidPeso molecular:557.62IACS-8968 R-enantiomer
CAS:<p>IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).</p>Fórmula:C17H18F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:381.35hCAIX-IN-8
CAS:<p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>Fórmula:C19H16N4O6Cor e Forma:SolidPeso molecular:396.35SK-216
CAS:<p>SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.</p>Fórmula:C29H29NNa2O6Pureza:98.29%Cor e Forma:SolidPeso molecular:533.52NCT-506
CAS:<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Fórmula:C25H23FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:478.54IDO1-IN-2
CAS:<p>IDO1-IN-2 is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse), and 28 nM (rat), respectively. It has anti-cancer activity.</p>Fórmula:C15H17FN6O4Pureza:98%Cor e Forma:SolidPeso molecular:364.33D-threo-PPMP hydrochloride
CAS:<p>D-threo-PPMP inhibits GlyCer synthetase; active enantiomer; reduces MDCK cell growth by 70% at 20 μM.</p>Fórmula:C29H51ClN2O3Cor e Forma:SolidPeso molecular:511.19IDO-IN-11
CAS:<p>IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell).</p>Fórmula:C19H23BrFN7O4SPureza:98%Cor e Forma:SolidPeso molecular:544.4BI-4924
CAS:<p>BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.</p>Fórmula:C21H20Cl2N2O6SPureza:99.55%Cor e Forma:SolidPeso molecular:499.36NPD-1335
CAS:<p>NPD1335: potent TbrPDEB1 inhibitor, submicromolar efficacy, low toxicity, raises cAMP, disrupts cell cycle, kills T. brucei.</p>Fórmula:C28H29N3O3Pureza:98%Cor e Forma:SolidPeso molecular:455.55Lovastatin hydroxy acid sodium
CAS:<p>Lovastatin Sodium is an HMG-CoA reductase inhibitor.</p>Fórmula:C24H38NaO6Cor e Forma:SolidPeso molecular:445.54CS-722 Free base
CAS:<p>CS-722 Free base: synthetic muscle relaxant; inhibits spinal reflex and sodium/calcium currents affecting synaptic activity.</p>Fórmula:C16H19ClN2O4Pureza:99.52%Cor e Forma:SolidPeso molecular:338.79Sch 34826
CAS:<p>Sch 34826 is a potent, selective neutral endopeptidase inhibitor.</p>Fórmula:C27H34N2O7Pureza:98%Cor e Forma:SolidPeso molecular:498.57Boc-Glu(OBzl)-OSu
CAS:<p>Boc-Glu(OBzl)-OSu can be used for the synthesis of solid phase peptides containing benzyl glutamate residues.</p>Fórmula:C21H26N2O8Cor e Forma:SolidPeso molecular:434.44AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Fórmula:C14H22N2OSPureza:98%Cor e Forma:SolidPeso molecular:266.4JTP-4819
CAS:<p>JTP-4819: potent PEP inhibitor, may treat Alzheimer's, boosts brain peptides and acetylcholine, aiding memory.</p>Fórmula:C19H25N3O4Cor e Forma:SolidPeso molecular:359.42DO-264
CAS:<p>DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.</p>Fórmula:C23H20Cl2F3N5O2SPureza:97.72% - 99.95%Cor e Forma:SolidPeso molecular:558.4hCAXII-IN-5
CAS:<p>hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.</p>Fórmula:C23H22N2O4Cor e Forma:SolidPeso molecular:390.43Andolast
CAS:<p>Andolast (CR-2039) is an anti-allergic for asthma and COPD, inhibiting IgE synthesis and improving airflow.</p>Fórmula:C15H11N9OCor e Forma:SolidPeso molecular:333.31sEH inhibitor-14
CAS:<p>sEH inhibitor-14, a benzoxazolone-5-urea analogue, acts as an efficient soluble Epoxide Hydrolase (sEH) inhibitor, demonstrating significant activity with an</p>Fórmula:C16H12F3N3O4Cor e Forma:SoildPeso molecular:367.28Carbonic anhydrase inhibitor 14
CAS:<p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>Fórmula:C18H17N7O2SCor e Forma:SolidPeso molecular:395.44Deltazinone
CAS:<p>Deltazinone selectively inhibits PDEδ with low cytotoxicity, mimicking PDEδ knockdown in human pancreatic cancer cells.</p>Fórmula:C27H31N5O2Pureza:98%Cor e Forma:SolidPeso molecular:457.57Niraparib metabolite M1
CAS:<p>Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1) is the carboxylic acid metabolite of niraparib.</p>Fórmula:C19H19N3O2Pureza:99.65%Cor e Forma:SolidPeso molecular:321.37MitoTEMPO hydrate
CAS:<p>MitoTEMPO, a mitochondria-targeted antioxidant, scavenges superoxide and alkyl radicals supporting potential therapy for mitochondrial dysfunction.</p>Fórmula:C29H35N2O2P·Cl·H2OCor e Forma:SolidPeso molecular:528.04Phosphodiesterase-IN-1
CAS:<p>Phosphodiesterase-IN-1 (Compound 7), a phosphodiesterase (PDE) inhibitor, exhibits anti-Plasmodium and antiproliferative activities. It effectively inhibits P. falciparum (strain 3D7) with an IC 50 value of 0.64 μM [1].</p>Fórmula:C15H15FN4OCor e Forma:SolidPeso molecular:286.3Enpp-1-IN-5
CAS:<p>Enpp-1-IN-5 is a potent enpp-1 inhibitor with potential in cancer and infectious disease research.</p>Fórmula:C17H26N6O4SCor e Forma:SolidPeso molecular:410.49α-Glucosidase-IN-2
CAS:<p>α-Glucosidase-IN-2 (compound 5d) is a potent inhibitor of α-Glucosidase, exhibiting an inhibitory concentration (IC50) of 9.48 μM, and functions as an</p>Fórmula:C17H11N3O2S2Cor e Forma:SolidPeso molecular:353.42JNJ-42165279 dihydrochloride
CAS:<p>JNJ-42165279 (dihydrochloride) is an FAAH inhibitor with IC50 values of 70 nM for hFAAH and 313 nM for rFAAH, respectively [1].</p>Fórmula:C18H19Cl3F2N4O3Cor e Forma:SolidPeso molecular:483.72BKIDC-1553
CAS:<p>BKIDC-1553, an orally active antiglycolytic agent and bumped kinase inhibitor-derived compound, has a predicted half-life of approximately 17 hours in humans. It inhibits CYP2C8 and Angiotensin Converting Enzyme, making it suitable for cancer research [1].</p>Fórmula:C22H23N5O2Cor e Forma:SolidPeso molecular:389.45mIDH1-IN-1
CAS:<p>mIDH1-IN-1 is a selective mIDH1 inhibitor (IC50: 961.5 nM), blocks 2-HG production, and hinders IDH1 mutant cell growth (IC50: 41.8 nM).</p>Fórmula:C25H27N3O5Cor e Forma:SolidPeso molecular:449.5TK-642
CAS:<p>TK-642 is a potent and selective SHP2 inhibitor with oral activity, based on pyrazole and pyrazine structures (IC50 = 2.7 nmol/L). It effectively inhibits the proliferation of esophageal carcinoma cells and induces apoptosis, making it useful for studying esophageal cancer.</p>Fórmula:C17H20ClN7SCor e Forma:SolidPeso molecular:389.91UK-414,495
CAS:<p>UK-414,495 is a potent, selective inhibitor of the neutral endopeptidase, the enzyme normally serves to break down the neuropeptide VIP.</p>Fórmula:C16H25N3O3SCor e Forma:SolidPeso molecular:339.45PDE4-IN-9
CAS:<p>PDE4-IN-9, a potent PDE4 inhibitor, has an IC50 of 1.4μM (better than rolipram) and is effective in LPS-induced asthma/COPD and sepsis models.</p>Fórmula:C15H12N4O3SCor e Forma:SolidPeso molecular:328.35AMG-7980
CAS:<p>AMG-7980 is a highly specific phosphodiesterase 10A ligand. It shows a good uptake in the striatum.</p>Fórmula:C19H22N4O2Pureza:98%Cor e Forma:SolidPeso molecular:338.4ROR Modulator I
CAS:<p>ROR Modulator I is the first potent inverse agonist of the retinoid-related orphan receptor. It also has dual selectivity for RORβ and RORγt.</p>Fórmula:C26H20Cl2N2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:559.48IM176OUT05
CAS:<p>IM176OUT05 activates stem cell metabolism with hair regrowth-promoting effects.</p>Fórmula:C11H17N5Cor e Forma:SolidPeso molecular:219.29PDE9-IN-1
CAS:<p>PDE9-IN-1 is a selective and orally bioavailable Inhibitor of PDE9A(IC50 of 8.7 nM).</p>Fórmula:C17H23FN6O2Pureza:99.86%Cor e Forma:SolidPeso molecular:362.4BDM14471
CAS:<p>BDM14471 is a selective inhibitor of hydroxamate PfAM1.</p>Fórmula:C17H15FN2O3Pureza:98%Cor e Forma:SolidPeso molecular:314.31AX 048
CAS:<p>Group IVA cPLA2 inhibitor AX 048 halts arachidonic acid release, preventing prostaglandin production, with XI(50) of 0.022 and ED50 of 1.2 mg/kg.</p>Fórmula:C22H41NO4Cor e Forma:SolidPeso molecular:383.57TUPS
CAS:<p>TUPS is a selective soluble epoxide hydrolase inhibitor which protects against isoprenaline-induced cardiac hypertrophy.</p>Fórmula:C14H18F3N3O4SCor e Forma:SolidPeso molecular:381.37α-Glucosidase-IN-10
CAS:<p>α-Glucosidase-IN-10 (compound 13) is a potent inhibitor of α-glucosidase (IC50: 92.7 μM). α-Glucosidase-IN-10 can be used to study type II diabetes.</p>Fórmula:C21H15BrN4O2SCor e Forma:SolidPeso molecular:467.34
