Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8595 produtos de "Metabolismo"
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ASP3662
CAS:<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Fórmula:C19H16ClF3N4O2Cor e Forma:SolidPeso molecular:424.8TM-1
CAS:<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Fórmula:C26H32N2O6Cor e Forma:SolidPeso molecular:468.54Pancreatic lipase/Carboxylesterase 1-IN-1
CAS:<p>Compound 39 is a dual inhibitor of PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM).</p>Fórmula:C30H44O4Cor e Forma:SolidPeso molecular:468.67SHP504
CAS:<p>SHP504 is an inhibitor of SHP2 phosphatase and acts on SHP21-525 (IC50: 21 μM).</p>Fórmula:C23H15ClN4O4Cor e Forma:SolidPeso molecular:446.84CAY10762
CAS:<p>CAY10762, a MAGL inhibitor (IC50=34.1 nM), curbs H2O2-induced LDH in Neuro2a cells and boosts 2-AG in mouse brains at 10 mg/kg.</p>Fórmula:C15H13NOSCor e Forma:SolidPeso molecular:255.33DNS-8254
CAS:<p>DNS-8254: Potent, selective PDE2 inhibitor, enhances memory (IC50=8 nM), effective in rat memory tests.</p>Fórmula:C18H15BrF3N5OPureza:98%Cor e Forma:SolidPeso molecular:454.24Enpp-1-IN-10
CAS:<p>Enpp-1-IN-10 inhibits ENPP1 with 3.866 μM Ki, useful in cancer research.</p>Fórmula:C13H12N6OSCor e Forma:SolidPeso molecular:300.34CAY10486
CAS:<p>CAY10486 blocks ACAT-1/2, which form cholesterol esters, potentially reducing atherosclerosis; inhibits LDL oxidation. IC50 ~60μM; 28% effect at 3μM.</p>Fórmula:C19H19NO4Cor e Forma:SolidPeso molecular:325.36Valibose
CAS:<p>Valibose, α-glucosidase inhibitor, improves glucose/lipid metabolism, lowers serum BUN/NAG, reduces kidney weight index.</p>Fórmula:C10H21NO6Cor e Forma:SolidPeso molecular:251.28(R)-Irsenontrine
CAS:<p>(R)-Irsenontrine (R-E2027), R-enantiomer, is a potent PDE9 inhibitor, IC50 = 0.041 μM, for neurological disease research.</p>Fórmula:C22H22N4O3Cor e Forma:SolidPeso molecular:390.44OHM1
CAS:<p>OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53</p>Fórmula:C24H42N6O5Cor e Forma:SolidPeso molecular:494.63Liarozole dihydrochloride
CAS:<p>Liarozole dihydrochloride, an oral CYP450 inhibitor, blocks estrogen and androgens, targeting prostate cancer and skin disorders.</p>Fórmula:C17H15Cl3N4Pureza:98%Cor e Forma:SolidPeso molecular:381.69Cycloguanil
CAS:<p>Cycloguanil is an antimalarial.</p>Fórmula:C11H14ClN5Pureza:98%Cor e Forma:SolidPeso molecular:251.72hCAXII-IN-2
CAS:<p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>Fórmula:C21H18ClN3O4Cor e Forma:SolidPeso molecular:411.84Teglicar
CAS:<p>Teglicar is a selective and reversible liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor.</p>Fórmula:C22H45N3O3Pureza:98%Cor e Forma:SolidPeso molecular:399.61α-Glucosidase-IN-16
CAS:<p>α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM.</p>Fórmula:C22H18FNSCor e Forma:SolidPeso molecular:347.45AChE/hCA I/II-IN-1
CAS:<p>Compound 6: Potent inhibitor for AChE, Hca I & II with IC50s of 22.21, 60.79, 66.64 nM, useful in glaucoma, Alzheimer's, diabetes research.</p>Fórmula:C15H13N3SCor e Forma:SolidPeso molecular:267.35AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Fórmula:C30H33F2NO4Pureza:98%Cor e Forma:SolidPeso molecular:509.58Kojibiose
CAS:<p>Kojibiose (Kojibiose) is a disaccharide in honey. Kojibiose is a product of the caramelization of glucose.</p>Fórmula:C12H22O11Pureza:99.933%Cor e Forma:SolidPeso molecular:342.3ALDH3A1-IN-2
CAS:<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Fórmula:C11H14N2O3Cor e Forma:SolidPeso molecular:222.24Gemlapodect
CAS:<p>Gemlapodect (RO554965), a phosphodiesterase 10A (PDE10A) inhibitor, is utilized in schizophrenia research.</p>Fórmula:C22H21N7O3Cor e Forma:SolidPeso molecular:431.454,6-O-Ethylidene-α-D-glucose
CAS:<p>4,6-O-Ethylidene-α-D-glucose (Ethylidene-glucose), a derivative of glucose, serves as a competitive inhibitor for the exofacial binding site of glucose</p>Fórmula:C8H14O6Cor e Forma:SolidPeso molecular:206.19SAR127303
CAS:<p>SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.</p>Fórmula:C16H17ClF6N2O4SPureza:98%Cor e Forma:SolidPeso molecular:482.83PSB069
CAS:<p>NTPDase inhibitor</p>Fórmula:C20H13ClN2NaO5SPureza:98%Cor e Forma:SolidPeso molecular:451.84(E/Z)-Ensifentrine
CAS:<p>RPL-554 (LS-193,855) is a dual PDE3/4 inhibitor with bronchodilator and anti-inflammatory properties, in trials for asthma and hay fever by Verona Pharma.</p>Fórmula:C26H31N5O4Cor e Forma:SolidPeso molecular:477.56IDO1-IN-18
CAS:<p>IDO1-IN-18 (Compound 14) is a potent inhibitor of IDO1. IDO1-IN-18 has potential for cancer disease research.</p>Fórmula:C23H18F4N2O3Cor e Forma:SolidPeso molecular:446.39BAY 73-6691
CAS:<p>BAY 73-6691 is an inhibitor of brain penetrant PDE9A.</p>Fórmula:C15H12ClF3N4OCor e Forma:SolidPeso molecular:356.73Y-29794
CAS:<p>Y-29794, a covalent POP inhibitor with a Ki of 0.95 nM, holds research potential for neurodegenerative diseases and cancer.</p>Fórmula:C22H32N2OS2Cor e Forma:SolidPeso molecular:404.63Pimobendan hydrochloride
CAS:<p>Pimobendan hydrochloride is a selective inhibitor of PDE3 (IC50: 0.32 μM).</p>Fórmula:C19H19ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:370.83YC-001
CAS:<p>YC-001: inverse agonist/antagonist for rod opsin, prevents light-induced retinal degeneration.</p>Fórmula:C12H7ClO2S2Cor e Forma:SolidPeso molecular:282.77SQ 27786
CAS:<p>SQ 27786 is an inhibitor of ACE.</p>Fórmula:C23H25ClN4O7S2Pureza:98%Cor e Forma:SolidPeso molecular:569.05Win 58237
CAS:<p>Win 58237 is an inhibitor of cyclic nucleotide phosphodiesterase (PDE) (Ki: 170 nM for PDE V), with vasorelaxant activity.</p>Fórmula:C16H17N5OPureza:98%Cor e Forma:SolidPeso molecular:295.34YM 26734
CAS:<p>Competitive inhibitor of secretory phospholipase A2 (sPLA2)</p>Fórmula:C45H62O8Pureza:98%Cor e Forma:SolidPeso molecular:730.97Imidazoleacetic acid
CAS:<p>Imidazoleacetic acid, an endogenous ligand, stimulates imidazole receptors.</p>Fórmula:C5H6N2O2Pureza:98%Cor e Forma:SolidPeso molecular:126.11LAS-31180
CAS:<p>LAS-31180 is a phosphodiesterase 3 inhibitor. It also has positive inotropic and vasodilator properties.</p>Fórmula:C11H12N2O3SPureza:98%Cor e Forma:SolidPeso molecular:252.29DMPAC-Chol
CAS:<p>DMPAC-Chol, a cationic cholesterol, aids gene transfection, DNA protection, binds DNA, and lowers HepG2 viability at 37.5 μg/ml.</p>Fórmula:C33H58N2O2Cor e Forma:SolidPeso molecular:514.83IHVR-19029
CAS:<p>IHVR-19029: ER α-glucosidases I/II inhibitor, IC50 0.48μM; halts Ebola, Dengue, Rift Valley fever virus replication.</p>Fórmula:C23H45N3O5Cor e Forma:SolidPeso molecular:443.62hCAIX-IN-7
CAS:<p>hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).</p>Fórmula:C18H12FNO3Cor e Forma:SolidPeso molecular:309.29GSK360A
CAS:<p>GSK360A is a novel prolyl hydroxylase (PHD) domain-containing enzyme inhibitor.</p>Fórmula:C17H17FN2O5Pureza:98%Cor e Forma:SolidPeso molecular:348.33ML202
CAS:<p>ML202 activates human pyruvate kinase M2, affecting PEP cooperativity with minimal impact on ADP binding.</p>Fórmula:C18H17N3O3S2Cor e Forma:SolidPeso molecular:387.48Xanthine oxidoreductase-IN-1
CAS:<p>Xanthine oxidoreductase-IN-1 is a xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 7.0 nM.</p>Fórmula:C18H20N4O2Cor e Forma:SolidPeso molecular:324.38SCD1-IN-1
CAS:<p>SCD1-IN-1, a potent inhibitor of SCD1 (IC50: 5.8 nM), is valuable in dermatologic research [1].</p>Fórmula:C20H20F3NO4Cor e Forma:SolidPeso molecular:395.37GNE-3500
CAS:<p>GNE-3500: potent, selective RORc inverse agonist; orally bioavailable; promising for treating inflammatory diseases.</p>Fórmula:C24H30FN3O3SCor e Forma:SolidPeso molecular:459.58HS80
CAS:<p>HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).</p>Fórmula:C19H22N4SPureza:98%Cor e Forma:SolidPeso molecular:338.47YM-75466
CAS:<p>YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.</p>Fórmula:C28H35N5O8S2Cor e Forma:SolidPeso molecular:633.74HX-600
CAS:<p>HX-600 is a synthetic agonist for the RXR-Nurr1 heterodimer complex. HX-600 prevents ischemia-induced neuronal damage.</p>Fórmula:C29H30N2O2Cor e Forma:SolidPeso molecular:438.56(Rac)-3′-Hydroxy simvastatin
CAS:<p>(Rac)-3′-Hydroxy Simvastatin, a metabolite of Simvastatin, acts as a competitive inhibitor of HMG-CoA reductase, demonstrating a K i value of 0.2 nM.</p>Fórmula:C25H38O6Cor e Forma:SolidPeso molecular:434.57NSC117079
CAS:<p>NSC117079 is a novel PHLPP1/2 (Pleckstrin homology domain and leucine rich repeat protein phosphatase) inhibitor that activates neuronal AKT .</p>Fórmula:C20H15N3O7S2Pureza:98.11%Cor e Forma:SolidPeso molecular:473.48EN40
CAS:<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Fórmula:C13H15NO2Cor e Forma:SolidPeso molecular:217.26BMS 740808
CAS:<p>BMS-740808 is a highly effective and selective factor X inhibitor.</p>Fórmula:C31H27F3N6O3Cor e Forma:SolidPeso molecular:588.58TMCB
CAS:<p>CK2 and ERK8 inhibitor</p>Fórmula:C11H9Br4N3O2Pureza:98%Cor e Forma:SolidPeso molecular:534.82ROR agonist-1
CAS:<p>Potent RORC2 inverse agonist, ROR agonist-1, inhibits IL-17A in TH17 cells, pIC50=7.5, orally active.</p>Fórmula:C21H20F6N2O5SPureza:98%Cor e Forma:SolidPeso molecular:526.45Lovastatin hydroxy acid sodium
CAS:<p>Lovastatin Sodium is an HMG-CoA reductase inhibitor.</p>Fórmula:C24H38NaO6Cor e Forma:SolidPeso molecular:445.54Fadrozole HCl hydrate
CAS:<p>Fadrozole is a selective inhibitor of aromatase. It also effective in the treatment of estrogen-dependent diseases including breast cancer.</p>Fórmula:C14H13N3ClHH2OPureza:98%Cor e Forma:SolidPeso molecular:268.74α-Glucosidase-IN-20
CAS:<p>α-Glucosidase-IN-20 (Compound 3B) is a highly effective and orally active inhibitor of α-glucosidase.</p>Fórmula:C23H21NOSCor e Forma:SolidPeso molecular:359.48trans-Ned 19
CAS:<p>trans-Ned 19 blocks NAADP and TPC, hindering calcium signaling and aorta relaxation at low histamine levels.</p>Fórmula:C30H31FN4O3Pureza:98%Cor e Forma:SolidPeso molecular:514.59Gcase activator 3
CAS:<p>Gcase activator 3 is a glucocerebrosidase (GCase) activator that enhances GBA1 mutant fibroblast lysosomal GCase activity.</p>Fórmula:C23H20N4O2Pureza:99.08%Cor e Forma:SolidPeso molecular:384.43Lp-PLA2-IN-11
CAS:<p>Lp-PLA2-IN-11, a potent Lp-PLA2 inhibitor, may be explored for atherosclerosis and Alzheimer's (WO2014114249A1, E145).</p>Fórmula:C22H20F4N4O3Cor e Forma:SolidPeso molecular:464.41Chaetomellic acid A
CAS:<p>Chaetomellic acid A inhibits farnesyltransferase (IC50=55nM), not active in cells, and selective over geranylgeranyltransferases (IC50: 92µM, 34µM).</p>Fórmula:C19H34O4Cor e Forma:SolidPeso molecular:326.47DHODH-IN-21
CAS:<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Fórmula:C20H19ClF4N6O4Cor e Forma:SolidPeso molecular:518.85hCA I-IN-1
CAS:<p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57LEO-29102
CAS:<p>LEO-29102: Potent, selective PDE4 inhibitor, promising for treating skin diseases, phase 2 efficacy in atopic dermatitis.</p>Fórmula:C20H22Cl2N2O5Cor e Forma:SolidPeso molecular:441.31Glucosylceramide synthase-IN-1
CAS:<p>Potent oral GCS inhibitor T-036, crosses BBB, targets human (IC50: 31 nM) and mouse GCS (IC50: 51 nM), for Gaucher disease research.</p>Fórmula:C24H20F4N2O3Cor e Forma:SolidPeso molecular:460.42α-Glycosidase-IN-1
CAS:<p>α-Glycosidase-IN-1 (compound MZ7) is a potent inhibitor of α-GLY (α-glycosidase) (IC50: 44.72 nM, Ki: 44.74 nM).</p>Fórmula:C21H19N9O6S2Cor e Forma:SolidPeso molecular:557.56Agn 190727
CAS:<p>Agn 190727 is a retonoic acid receptor that can induce retinoid-induced hypertriglyceridemia.</p>Fórmula:C20H22O2Cor e Forma:SolidPeso molecular:294.39ALDH1A1-IN-3
CAS:<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Fórmula:C31H36F3N5O4Cor e Forma:SolidPeso molecular:599.64(Rac)-RK-682
CAS:<p>(Rac)-RK-682 racemate; inhibits PTP-1B, LMW-PTP, CDC-25B with IC50s: 8.6, 12.4, 0.7 µM respectively.</p>Fórmula:C21H36O5Cor e Forma:SolidPeso molecular:368.51RYL-552
CAS:<p>RYL-552 is a potent inhibitor of PfNDH2.</p>Fórmula:C24H17F4NO2Pureza:98%Cor e Forma:SolidPeso molecular:427.39HIF-1α-IN-3
CAS:<p>HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].</p>Fórmula:C19H17N5O2Cor e Forma:SolidPeso molecular:347.37hCAIX/XII-IN-2
CAS:<p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).</p>Fórmula:C19H14N2O4Cor e Forma:SolidPeso molecular:334.33Delapril
CAS:<p>Delapril is an ACE inhibitor. It blocks the conversion of angiotensin I to angiotensin II.</p>Fórmula:C26H32N2O5Pureza:98%Cor e Forma:SolidPeso molecular:452.54DO-264
CAS:<p>DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.</p>Fórmula:C23H20Cl2F3N5O2SPureza:97.72% - 99.95%Cor e Forma:SolidPeso molecular:558.4GKA-71
CAS:<p>GKA-71 is an effective glucokinase activator (GKA).</p>Fórmula:C21H23N3O6S2Cor e Forma:SolidPeso molecular:477.55JNJ-61803534
CAS:<p>JNJ-61803534: RORγt inverse agonist, IC50=9.6 nM, oral, anti-inflammatory, reduces IL-17A in T cells.</p>Fórmula:C23H23Cl2F6N3O4SCor e Forma:SolidPeso molecular:622.41Umbralisib tosylate
CAS:<p>Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.</p>Fórmula:C38H32F3N5O6SCor e Forma:SolidPeso molecular:743.75MDK-4823
CAS:<p>MDK-4823 (LMPTP inhibitor1) blocks LMPTP, fighting insulin resistance and diabetes in obesity.</p>Fórmula:C28H36N4OCor e Forma:SolidPeso molecular:444.61Enpp-1-IN-8
CAS:<p>Enpp-1-IN-8: potent inhibitor of enpp-1, an enzyme breaking down various nucleotide bonds; potential in cancer/infectious disease research.</p>Fórmula:C19H26N6O4SCor e Forma:SolidPeso molecular:434.51FAAH-IN-7
<p>FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.</p>Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53TC-E 5005
CAS:<p>PDE10A inhibitor</p>Fórmula:C15H18N4OPureza:98%Cor e Forma:SolidPeso molecular:270.33MAGLi 432
CAS:<p>MAGLi 432: Potent MAGL inhibitor, selective and reversible. IC50: 4.2 nM (human), 3.1 nM (mouse). Useful for neurological disorder research.</p>Fórmula:C22H24BrClN2O2Cor e Forma:SolidPeso molecular:463.8PDE11-IN-1
CAS:<p>PDE11-IN-1 is a PDE11 inhibitor and can be used for adrenal insufficiency research [1].</p>Fórmula:C16H10ClN3O3SCor e Forma:SolidPeso molecular:359.79CP 80633
CAS:<p>CP 80633 is a PDE4 inhibitor.</p>Fórmula:C18H24N2O3Pureza:98%Cor e Forma:SolidPeso molecular:316.39hCAIX-IN-3
CAS:<p>hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.</p>Fórmula:C21H21BrN6O4SCor e Forma:SolidPeso molecular:533.4Fmoc-5-aminopentanoic acid
CAS:<p>Fmoc-5-aminopentanoic acid: alkane, Fmoc-protected amine, carboxyl group, PROTAC linker, deprotects to free amine, forms amides with activators.</p>Fórmula:C20H21NO4Cor e Forma:SolidPeso molecular:339.39Acetylhydrolase-IN-1
CAS:<p>Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).</p>Fórmula:C23H48NO7PPureza:98%Cor e Forma:SolidPeso molecular:481.6PKM2 activator 4
CAS:<p>PKM2 Activator 4, a chemical compound, functions as an activator of PKM2 with an activation concentration (AC 50) ranging from 1 to 10 μM.</p>Fórmula:C16H16N2O4SCor e Forma:SolidPeso molecular:332.37M77976
CAS:<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Fórmula:C17H16N2O3Pureza:99.43%Cor e Forma:SolidPeso molecular:296.32SGK1-IN-2
CAS:<p>SGK1-IN-2 (14h) is a selective inhibitor of SGK1 (serum and glucocorticoid regulated kinase 1)(with an IC50 of 5 nM at 10 μM ATP concentration).</p>Fórmula:C17H12Cl2N6O2SPureza:98%Cor e Forma:SolidPeso molecular:435.29Spirapril
CAS:<p>Spiropril is an ACE inhibitor antihypertensive drug, which belongs to the bicarboxyl group of ACE inhibitors and is used in the treatment of hypertension.</p>Fórmula:C22H30N2O5S2Cor e Forma:SolidPeso molecular:466.61Benserazide
CAS:<p>Benserazide blocks dopa decarboxylase; paired with levodopa for Parkinson's to boost CNS dopamine levels and lower dosage.</p>Fórmula:C10H15N3O5Cor e Forma:SolidPeso molecular:257.24Carbonic anhydrase inhibitor 7
CAS:<p>Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.</p>Fórmula:C23H17N3O5SCor e Forma:SolidPeso molecular:447.46IDO1-IN-15
CAS:<p>IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro.</p>Fórmula:C13H14BrFN6O3Cor e Forma:SolidPeso molecular:401.19Arasertaconazole
CAS:<p>Arasertaconazole, a sterol-14-alpha demethylation inhibitor, is used potentially for the treatment of vulvovaginal candcanidiasis.</p>Fórmula:C20H15Cl3N2OSCor e Forma:SolidPeso molecular:437.77A-908292
CAS:<p>A-908292: potent ACC2 inhibitor with 38 nM IC50, useful for studying fatty acid metabolism.</p>Fórmula:C18H20N2O4SCor e Forma:SolidPeso molecular:360.43FABP-IN-2
CAS:<p>FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.</p>Fórmula:C25H21ClN2O3Cor e Forma:SolidPeso molecular:432.9hCAII-IN-2
CAS:<p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>Fórmula:C25H18ClN5O4SCor e Forma:SolidPeso molecular:519.96UKI-1
CAS:<p>UKI-1 is a urokinase-type plasminogen activator system synthetic inhibitor.</p>Fórmula:C32H47N5O5SPureza:98%Cor e Forma:SolidPeso molecular:613.81hCAXII-IN-1
CAS:<p>hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.</p>Fórmula:C20H17NO5Cor e Forma:SolidPeso molecular:351.35Genz-669178
CAS:<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Fórmula:C17H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:322.38MY33-3 hydrochloride
CAS:<p>MY33-3 HCl: Inhibits RPTPβ/ζ (IC50~0.1μM), PTP-1B (IC50~0.7μM), curbs alcohol intake, fights neuroinflammation and memory issues.</p>Fórmula:C16H14ClF6NS2Cor e Forma:SolidPeso molecular:433.86RP 73163 Racemate
CAS:<p>RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potent inhibitor of ACAT, shows cholesterol lowering activity.</p>Fórmula:C25H28N4OSPureza:98%Cor e Forma:SolidPeso molecular:432.58RORγt inverse agonist 30
CAS:<p>RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist (IC50: 46 nM).</p>Fórmula:C24H31N3O3SCor e Forma:SolidPeso molecular:441.59Y-29794 oxalate
CAS:<p>Inhibitor of prolyl endopeptidase</p>Fórmula:C25H36N2O5S2Pureza:98%Cor e Forma:SolidPeso molecular:508.69PDE4-IN-11
CAS:<p>PDE4-IN-11: Potent PDE4 inhibitor with strong bronchodilatory and anti-inflammatory effects for airway disease research.</p>Fórmula:C21H19FN2O2Cor e Forma:SolidPeso molecular:350.39Xanthine oxidase-IN-4
CAS:<p>Xanthine oxidase-IN-4: an oral XO inhibitor with 0.039 μM IC50, useful for hyperuricemia/gout research.</p>Fórmula:C15H13N5O2Cor e Forma:SolidPeso molecular:295.3PRRSV/CD163-IN-1
CAS:<p>PRRSV/CD163-IN-1 blocks PRRSV GP2a/GP4 and CD163-SRCR5, aiding PRRS research.</p>Fórmula:C25H24FN5O5S2Cor e Forma:SolidPeso molecular:557.62Desfluoro-atorvastatin
CAS:<p>Desfluoro-atorvastatin is an impurity of atorvastatin, an oral HMG-CoA reductase inhibitor that lowers blood lipids.</p>Fórmula:C33H36N2O5Pureza:98%Cor e Forma:SolidPeso molecular:540.65hCAIX-IN-8
CAS:<p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>Fórmula:C19H16N4O6Cor e Forma:SolidPeso molecular:396.35XEN103
CAS:<p>XEN103 is a potent and selective Stearoyl-CoA Desaturase-1 inhibitor.</p>Fórmula:C22H23F4N5O2Cor e Forma:SolidPeso molecular:465.44ICI 153110
CAS:<p>ICI 153110: Oral phosphodiesterase inhibitor for treating congestive heart failure, has inotropic, vasodilator effects.</p>Fórmula:C11H11N3OPureza:98%Cor e Forma:SolidPeso molecular:201.22Xanthine oxidase-IN-5
CAS:<p>Xanthine oxidase-IN-5: oral XO inhibitor, IC50 = 0.70 μM, LE = 0.33, LLE = 3.41, reduces uric acid in rats.</p>Fórmula:C18H16FN3O3Cor e Forma:SolidPeso molecular:341.34NPD-1335
CAS:<p>NPD1335: potent TbrPDEB1 inhibitor, submicromolar efficacy, low toxicity, raises cAMP, disrupts cell cycle, kills T. brucei.</p>Fórmula:C28H29N3O3Pureza:98%Cor e Forma:SolidPeso molecular:455.55Sch 34826
CAS:<p>Sch 34826 is a potent, selective neutral endopeptidase inhibitor.</p>Fórmula:C27H34N2O7Pureza:98%Cor e Forma:SolidPeso molecular:498.57Boc-Glu(OBzl)-OSu
CAS:<p>Boc-Glu(OBzl)-OSu can be used for the synthesis of solid phase peptides containing benzyl glutamate residues.</p>Fórmula:C21H26N2O8Cor e Forma:SolidPeso molecular:434.44FKGK11
CAS:<p>FKGK11 is a potent inhibitor of GVIA iPLA2.</p>Fórmula:C13H13F5OPureza:98%Cor e Forma:SolidPeso molecular:280.23AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Fórmula:C14H22N2OSPureza:98%Cor e Forma:SolidPeso molecular:266.4JTP-4819
CAS:<p>JTP-4819: potent PEP inhibitor, may treat Alzheimer's, boosts brain peptides and acetylcholine, aiding memory.</p>Fórmula:C19H25N3O4Cor e Forma:SolidPeso molecular:359.42Saterinone hydrochloride
CAS:<p>Saterinone hydrochloride is an inhibitor of phosphodiesterase III (PDE III).</p>Fórmula:C27H31ClN4O4Pureza:98%Cor e Forma:SolidPeso molecular:511.01Andolast
CAS:<p>Andolast (CR-2039) is an anti-allergic for asthma and COPD, inhibiting IgE synthesis and improving airflow.</p>Fórmula:C15H11N9OCor e Forma:SolidPeso molecular:333.31sEH inhibitor-14
CAS:<p>sEH inhibitor-14, a benzoxazolone-5-urea analogue, acts as an efficient soluble Epoxide Hydrolase (sEH) inhibitor, demonstrating significant activity with an</p>Fórmula:C16H12F3N3O4Cor e Forma:SoildPeso molecular:367.28CDK2-IN-12
CAS:<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Fórmula:C20H17N9O2SCor e Forma:SolidPeso molecular:447.47Quinethazone
CAS:<p>Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.</p>Fórmula:C10H12ClN3O3SCor e Forma:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Peso molecular:289.74Deltazinone
CAS:<p>Deltazinone selectively inhibits PDEδ with low cytotoxicity, mimicking PDEδ knockdown in human pancreatic cancer cells.</p>Fórmula:C27H31N5O2Pureza:98%Cor e Forma:SolidPeso molecular:457.57SGK1 inhibitor
CAS:<p>SGK1 inhibitor targets SGK1/2 over SGK3, blocks GSK3β phosphorylation, lowers HCC1954 cell viability with BYL719, and reduces tumor growth in mice.</p>Fórmula:C17H12Cl2N6O2SCor e Forma:SolidPeso molecular:435.29CAY10485
CAS:<p>CAY10485 blocks human ACAT-1 & ACAT-2 (IC50: 95 & 81 μM) and hinders oxidation of LDL by 91% at 2 μM, possibly impacting atherosclerosis development.</p>Fórmula:C27H27NO7Cor e Forma:SolidPeso molecular:477.51PDE-9 inhibitor
CAS:<p>PDE-9 inhibitor is used for treatment neurodegenerative diseases.</p>Fórmula:C22H27N5O2Pureza:98%Cor e Forma:SolidPeso molecular:393.48L-Canaline
CAS:<p>L-Canaline is a nonprotein amino acid with IC50 of 297 nM against malaria, anticancer properties, and blocks ornithine aminotransferase.</p>Fórmula:C4H10N2O3Pureza:98%Cor e Forma:SolidPeso molecular:134.13PKR activator 1
CAS:<p>PKR activator 1 is a potent activator of pyruvate kinase-R (PKR).</p>Fórmula:C16H14N8OS2Pureza:98%Cor e Forma:SolidPeso molecular:398.47ATX inhibitor 11
CAS:<p>ATX inhibitor 11 blocks autotaxin (IC50: 2.7 nM), reduces fibrosis and α-SMA in mice. Useful for lung fibrosis studies.</p>Fórmula:C32H35N5O6Cor e Forma:SolidPeso molecular:585.65AMG-7980
CAS:<p>AMG-7980 is a highly specific phosphodiesterase 10A ligand. It shows a good uptake in the striatum.</p>Fórmula:C19H22N4O2Pureza:98%Cor e Forma:SolidPeso molecular:338.4AX 048
CAS:<p>Group IVA cPLA2 inhibitor AX 048 halts arachidonic acid release, preventing prostaglandin production, with XI(50) of 0.022 and ED50 of 1.2 mg/kg.</p>Fórmula:C22H41NO4Cor e Forma:SolidPeso molecular:383.57TUPS
CAS:<p>TUPS is a selective soluble epoxide hydrolase inhibitor which protects against isoprenaline-induced cardiac hypertrophy.</p>Fórmula:C14H18F3N3O4SCor e Forma:SolidPeso molecular:381.37α-Glucosidase-IN-10
CAS:<p>α-Glucosidase-IN-10 (compound 13) is a potent inhibitor of α-glucosidase (IC50: 92.7 μM). α-Glucosidase-IN-10 can be used to study type II diabetes.</p>Fórmula:C21H15BrN4O2SCor e Forma:SolidPeso molecular:467.34Glucokinase activator 3
CAS:<p>Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.</p>Fórmula:C26H33N2O9PS2Cor e Forma:SolidPeso molecular:612.65Asp-AMS
CAS:<p>Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.</p>Fórmula:C14H19N7O9SCor e Forma:SolidPeso molecular:461.41Eggmanone
CAS:<p>EGM1: potent PDE4D3 inhibitor, IC50=72 nM, 40-50x selectivity over other PDEs, activates PKA, blocks Hh.</p>Fórmula:C20H20N2O2S3Cor e Forma:SolidPeso molecular:416.58hCAIX-IN-6
CAS:<p>6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.</p>Fórmula:C18H12N2O4SCor e Forma:SolidPeso molecular:352.36Carbonic anhydrase inhibitor 13
CAS:<p>Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).</p>Fórmula:C17H15N5O3S2Cor e Forma:SolidPeso molecular:401.46IDO1-IN-17
CAS:<p>IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells .</p>Fórmula:C28H32BrClFN5O2Cor e Forma:SolidPeso molecular:604.94IDO-IN-14
CAS:<p>IDO-IN-14 is an IDO inhibitor (IC50: 0.6928 nM).</p>Fórmula:C23H23ClN4O2Cor e Forma:SolidPeso molecular:422.91FAAH-IN-5
CAS:<p>FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.</p>Fórmula:C21H19N3O6SCor e Forma:SolidPeso molecular:441.46IDH2R140Q-IN-1
CAS:<p>IDH2R140Q-IN-1 is a potent inhibitor of IDH2R140Q (IC50: 6.1 nM) and can be used in studies of acute myeloid leukemia.</p>Fórmula:C22H20F6N6Cor e Forma:SolidPeso molecular:482.42HIF-1/2α-IN-2
CAS:<p>HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α.</p>Fórmula:C16H11FN4O2SCor e Forma:SolidPeso molecular:342.35OMDM-3
CAS:<p>OMDM-3 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 16.6 μM).</p>Fórmula:C29H43NO3Pureza:98%Cor e Forma:SolidPeso molecular:453.66CD 2314
CAS:<p>CD2314 is a potent and subtype-selective RARβ receptor agonist with a Kd of 195 nM in S91 melanoma cells [1].</p>Fórmula:C23H24O2SCor e Forma:SolidPeso molecular:364.5Phortress free base
CAS:<p>Phortress free base is a P450 CYP1A1-activated antitumor prodrug with antitumor activity.</p>Fórmula:C20H23FN4OSPureza:98%Cor e Forma:SolidPeso molecular:386.49NCX 1000
CAS:<p>NCX 1000 is a liver-specific NO donor compound,NCX 1000 derived from ursodeoxycholic acid (UDCA).</p>Fórmula:C38H55NO10Pureza:98%Cor e Forma:SolidPeso molecular:685.84PKR activator 2
CAS:<p>PKR activator 2 is a potent activator of pyruvate kinase-R (PKR).</p>Fórmula:C18H16N8OSPureza:98%Cor e Forma:SolidPeso molecular:392.44CK2-IN-6
CAS:<p>CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.</p>Fórmula:C19H16ClN7O2Cor e Forma:SolidPeso molecular:409.83RORγt modulator 2
CAS:<p>RORγt modulator 2 is a modulator of retinol-related orphan receptor γt (RORyt) (IC50<50 nM) and can be used in the study of RORγt-mediated diseases such as pain</p>Fórmula:C28H29ClN2O4SCor e Forma:SolidPeso molecular:525.06FXR agonist 4
<p>FXR agonist 4: EC50 of 1.05μM, treats hyperlipidemia, steatosis, insulin resistance, inflammation in DIO mice, for NAFLD research.</p>Fórmula:C21H28ClN3OCor e Forma:SolidPeso molecular:373.92LEI-106
CAS:<p>LEI-106 is an effective dual inhibitor of DAGL-α and ABHD6, with Ki values of 0.7 and 0.8 μM respectively, for obesity and metabolic syndrome research.</p>Fórmula:C26H27NO6SCor e Forma:SolidPeso molecular:481.56Phenylthiazolylthiourea
CAS:<p>Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.</p>Fórmula:C10H9N3S2Cor e Forma:SolidPeso molecular:235.33Protizinic acid
CAS:<p>Protizinic acid is an oral NSAID with anti-inflammatory and antipyretic properties, inhibiting PLA2 at IC50 of 210μM.</p>Fórmula:C17H17NO3SCor e Forma:SolidPeso molecular:315.39ACC1/2-IN-2
CAS:<p>PF-3: potent ACC1/2 inhibitor; IC50: 22 nM (ACC1), 48 nM (ACC2); anti-cancer research potential.</p>Fórmula:C24H25N3O3Cor e Forma:SolidPeso molecular:403.47CYP1B1-IN-3
CAS:<p>CYP1B1-IN-3: strong CYP1B1 inhibitor (IC50: 6.6 nM); weak on CYP1A1/CYP1A2; hinders cell migration, invasion; blocks P-gp, AKT/ERK, FAK/SRC, EMT.</p>Fórmula:C20H16FN3O2S2Cor e Forma:SolidPeso molecular:413.49Afegostat
CAS:<p>Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.</p>Fórmula:C6H13NO3Pureza:98%Cor e Forma:Yellow Low-Melting SolidPeso molecular:147.17CM39
CAS:<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Fórmula:C19H15FN4OSCor e Forma:SolidPeso molecular:366.41Oxythiamine diphosphate
CAS:<p>Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).</p>Fórmula:C12H17N3O8P2SPureza:98%Cor e Forma:SolidPeso molecular:425.29KT185
CAS:<p>KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21 nM in Neuro2A cells).</p>Fórmula:C32H33N5O2Pureza:98%Cor e Forma:SolidPeso molecular:519.64DTP348
CAS:<p>DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.</p>Fórmula:C6H11N5O4SCor e Forma:SolidPeso molecular:249.25Nitrefazole
CAS:<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Fórmula:C10H8N4O4Cor e Forma:SolidPeso molecular:248.19URB-694
CAS:<p>URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.</p>Fórmula:C19H21NO3Cor e Forma:SolidPeso molecular:311.3714(S)-HDHA
CAS:<p>DHA is an ω-3 important for development and therapy for inflammation and cancer; its derivative, 14(S)-HDHA, aids in reducing inflammation.</p>Fórmula:C22H32O3Cor e Forma:SolidPeso molecular:344.49Ambuphylline
CAS:<p>Ambuphylline (Bufylline) is a theophylline derivative and bronchodilator for asthma and lung disease research.</p>Fórmula:C11H19N5O3Cor e Forma:SolidPeso molecular:269.305Talarozole (R enantiomer)
CAS:<p>Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid.</p>Fórmula:C21H23N5SPureza:98%Cor e Forma:SolidPeso molecular:377.51DGAT1-IN-3
CAS:<p>DGAT1-IN-3: a potent, selective DGAT-1 inhibitor (IC50: 38 nM human, 120 nM rat), oral, for obesity and dyslipidemia research.</p>Fórmula:C20H19F3N4O3Cor e Forma:SolidPeso molecular:420.39Nampt-IN-7
CAS:<p>Nampt-IN-7 (GF8) inhibits NAMPT (IC50: 7.31 μM) and kills HepG2 cells (IC50: 24.28 μM).</p>Fórmula:C20H21N5O3Cor e Forma:SolidPeso molecular:379.41Rev 5975
CAS:<p>Rev 5975 is a non-sulfhydryl ACE-inhibitor.</p>Fórmula:C24H30N2O5Pureza:98%Cor e Forma:SolidPeso molecular:426.51(±)-γ-Tocopherol
CAS:<p>(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.</p>Fórmula:C28H48O2Cor e Forma:SolidPeso molecular:416.68Tyrphostin AG 1112
CAS:<p>Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.</p>Fórmula:C15H10N6Cor e Forma:SolidPeso molecular:274.28ONO-6126
CAS:<p>ONO-6126 has anti-inflammatory activity and can inhibit Phosphodiesterase and PDE4 in the treatment of respiratory diseases.</p>Fórmula:C20H27N3O4Pureza:98%Cor e Forma:SolidPeso molecular:373.45FASN-IN-4
CAS:<p>FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.</p>Fórmula:C26H27N3O4SPureza:98%Cor e Forma:SolidPeso molecular:477.58Glucocerebrosidase-IN-1
CAS:<p>Glucocerebrosidase-IN-1 inhibits GCase with IC50 of 29.3 μM, Ki 18.5 μM, useful for Gaucher's and Parkinson's research.</p>Fórmula:C13H27NO3Cor e Forma:SolidPeso molecular:245.36AMPD2 inhibitor 2
<p>AMPD2 inhibitor 2: strong h/mAMPD2 blocker, IC50s: 0.1/0.28μM. Potentially assesses AMPD2's role in high-fat diet mice.</p>Fórmula:C26H27F2N3O3Cor e Forma:SolidPeso molecular:467.51ME-143
CAS:<p>ME-143, a 2nd-gen NADH oxidase inhibitor, blocks WNT/β-catenin pathway, active against various cancers in vitro/vivo.</p>Fórmula:C21H18O4Cor e Forma:SolidPeso molecular:334.37Ciraparantag
CAS:<p>Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.</p>Fórmula:C22H48N12O2Pureza:98%Cor e Forma:SolidPeso molecular:512.7LEO 39652
CAS:<p>LEO 39652: Dual-soft PDE4 inhibitor, IC50s: PDE4A/B: 1.2 nM, PDE4C: 3.0 nM, PDE4D: 3.8 nM; TNF-α IC50: 6.0 nM; for Atopic dermatitis research.</p>Fórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.453-Oxo-hop-22(29)-ene
CAS:<p>3-Oxo-hop-22(29)-ene inhibits yeast α-glucosidase, moderately affects T. cruzi and L. mexicana, and has slight anti-inflammatory activity.</p>Fórmula:C30H48OCor e Forma:SolidPeso molecular:424.7hCAXII-IN-4
CAS:<p>hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.</p>Fórmula:C22H27N5O6SCor e Forma:SolidPeso molecular:489.54Antiproliferative agent-10
<p>Antiproliferative agent-10: Ruthenium(II) complex that blocks cancer cell growth by halting mitochondrial calcium uptake.</p>Fórmula:C35H36Cl2N7PRuCor e Forma:SolidPeso molecular:757.66Glyoxalase I inhibitor
CAS:<p>Glyoxalase I inhibitor, a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.</p>Fórmula:C21H30BrClN4O8SPureza:98%Cor e Forma:SolidPeso molecular:613.91Atreleuton
CAS:<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Fórmula:C16H15FN2O2SPureza:98%Cor e Forma:SolidPeso molecular:318.37MitoPBN
CAS:<p>MitoPBN: mitochondria-targeted antioxidant, inhibits UCP1-3 at 250 nM, traps hydroxyl & carbon radicals, prevents lipid peroxidation.</p>Fórmula:C33H37BrNO2PCor e Forma:SolidPeso molecular:590.542hCA I-IN-2
CAS:<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44LY 113174
CAS:<p>LY 113174, a novel nonsteroidal aromatase inhibitor, may prove useful in the treatment of estrogen-dependent diseases.</p>Fórmula:C17H10Cl2N2Cor e Forma:SolidPeso molecular:313.18FC11409B
CAS:<p>FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.</p>Fórmula:C29H23BF4N2O3SCor e Forma:SolidPeso molecular:566.38Cholesteryl Palmitoleate
CAS:<p>Cholesteryl palmitoleate, a cholesterol ester, exhibits elevated plasma levels in ApoE-/- mice following exposure to cigarette smoke and in pediatric patients diagnosed with biliary atresia. It serves as a standard for identifying cholesterol esters in human meibomian gland secretions.</p>Fórmula:C43H74O2Cor e Forma:SolidPeso molecular:623.1RORγt modulator 3
CAS:<p>RORγt modulator 3 is a modulator of retinol-related orphan receptor γt (RORγt) and can be used to study RORγt-mediated diseases such as pain, COPD, inflammation</p>Fórmula:C25H25ClFN3O4SCor e Forma:SolidPeso molecular:518Zidovudine glucuronide
CAS:<p>Zidovudine glucuronide: an NRTI antiretroviral for HIV/AIDS treatment; blocks HIV reverse transcriptase, stops viral DNA formation.</p>Fórmula:C16H21N5O10Cor e Forma:SolidPeso molecular:443.37Dapaconazole
CAS:<p>Dapaconazole is used as a drug candidate for antifungals.</p>Fórmula:C19H15Cl2F3N2OCor e Forma:SolidPeso molecular:415.24Lp-PLA2-IN-4
CAS:<p>Lp-PLA2-IN-4, a potent inhibitor of Lp-PLA2/PAF-AH, may target Alzheimer's, atherosclerosis. (WO2021228159A1, Compound 38)</p>Fórmula:C23H18F5N3O4Cor e Forma:SolidPeso molecular:495.4Flutolanil
CAS:<p>Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.</p>Fórmula:C17H16F3NO2Cor e Forma:SolidPeso molecular:323.31Ro 41-0960
CAS:<p>Ro 41-0960 is used as a reversible and orally-active COMT-inhibitor.</p>Fórmula:C13H8FNO5Pureza:98%Cor e Forma:SolidPeso molecular:277.2Acetaldophosphamide
CAS:<p>Acetaldophosphamide is a novel stable aldophosphamide analog.</p>Fórmula:C11H21Cl2N2O6PCor e Forma:SolidPeso molecular:379.17CP-532623
CAS:<p>CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.</p>Fórmula:C27H27F9N2O3Pureza:98%Cor e Forma:SolidPeso molecular:598.5JZP-MA-13
<p>JZP-MA-13: selective α/β-hydrolase domain 6 inhibitor, IC 50 392 nM, doesn't inhibit MAGL/ABHD12/FAAH, used in PET imaging.</p>Fórmula:C14H15FN4O3SCor e Forma:SolidPeso molecular:338.36BRD9500
CAS:<p>BRD9500 is an oral PDE3 inhibitor, IC50: 10 nM (PDE3A), 27 nM (PDE3B); effective in SK-MEL-3 cancer model.</p>Fórmula:C15H18FN3O2Cor e Forma:SolidPeso molecular:291.32Anti-hyperglycemic agent-1
CAS:<p>Anti-hyperglycemic agent 1 is a potent inhibitor of alpha-glucosidase (IC50: 0.53 μM). anti-Hyperglycemic agent 1 can be used to study diabetes.</p>Fórmula:C20H15BrN2O3Cor e Forma:SolidPeso molecular:411.25
