Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(165 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8597 produtos de "Metabolismo"
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Filaminast
CAS:<p>Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.</p>Fórmula:C15H20N2O4Pureza:98.53% - 98.93%Cor e Forma:SolidPeso molecular:292.33Lifibrol
CAS:<p>Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-</p>Fórmula:C21H26O4Pureza:99.96%Cor e Forma:SolidPeso molecular:342.43PDE IV-IN-1
CAS:<p>PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease</p>Fórmula:C20H23ClN4O2Pureza:99.79%Cor e Forma:SolidPeso molecular:386.88IMPDH2-IN-2
CAS:<p>IMPDH2-IN-2 is an IMPDH inhibitor with antimicrobial activity and potential anti-tuberculosis activity for the study of inflammation and immune dysfunction.</p>Fórmula:C21H15Cl2N3O3Pureza:99.02%Cor e Forma:SolidPeso molecular:428.27Troriluzole
CAS:<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Fórmula:C15H16F3N5O4SPureza:97.14%Cor e Forma:SolidPeso molecular:419.38Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Cor e Forma:SolidPeso molecular:548.06Tanimilast
CAS:<p>Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.</p>Fórmula:C30H30Cl2F2N2O8SPureza:98.34%Cor e Forma:SolidPeso molecular:687.54ALDH1A3-IN-2
CAS:<p>ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.</p>Fórmula:C13H17NOPureza:99.84%Cor e Forma:SolidPeso molecular:203.28Ch55
CAS:<p>Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.</p>Fórmula:C24H28O3Pureza:99.55%Cor e Forma:SolidPeso molecular:364.48Autotaxin-IN-3
CAS:<p>Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.</p>Fórmula:C22H21N9O2Pureza:99.54% - 99.79%Cor e Forma:SolidPeso molecular:443.46Fluorobexarotene
CAS:<p>Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.</p>Fórmula:C24H27FO2Pureza:99.08%Cor e Forma:SolidPeso molecular:366.47Dirlotapide
CAS:<p>Dirlotapide (CP742033), an intestinal MTP inhibitor, cuts weight in diabetic dogs by lowering food intake and raising peptide YY.</p>Fórmula:C40H33F3N4O3Pureza:98.47% - 99.62%Cor e Forma:SolidPeso molecular:674.71AM 374
CAS:<p>AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM.</p>Fórmula:C16H33FO2SPureza:98.39%Cor e Forma:SolidPeso molecular:308.5A-69412
CAS:<p>A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.</p>Fórmula:C7H10N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:170.17Qc1
CAS:<p>Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.</p>Fórmula:C23H16F3N3O2SPureza:99.75%Cor e Forma:SolidPeso molecular:455.45DSM421
CAS:<p>DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown</p>Fórmula:C14H11F5N6Pureza:98.23% - 99.82%Cor e Forma:SolidPeso molecular:358.27Didesethyl chloroquine
CAS:<p>Didesethyl chloroquine, a chloroquine metabolite, is an effective myocardial inhibitor and antimalarial.</p>Fórmula:C14H18ClN3Pureza:98.11%Cor e Forma:SolidPeso molecular:263.77GAC0003A4
CAS:<p>GAC0003A4 is an LXR inverse agonist with antitumor activity for the study of advanced pancreatic cancer and other recalcitrant malignancies.</p>Fórmula:C20H24N2O3Pureza:98.41%Cor e Forma:SolidPeso molecular:340.42Fumarate hydratase-IN-1
CAS:<p>Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.</p>Fórmula:C27H30N2O4Pureza:98.96% - 99.49%Cor e Forma:SolidPeso molecular:446.54IDH2R140Q-IN-2
CAS:<p>IDH2R140Q-IN-2 is an IDH2R140Q inhibitor indicated for the study of acute myeloid leukaemia (AML).</p>Fórmula:C21H18F6N6OPureza:99.92%Cor e Forma:SolidPeso molecular:484.4VU0155069
CAS:<p>VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.</p>Fórmula:C26H27ClN4O2Pureza:99.5%Cor e Forma:SolidPeso molecular:462.97Sultiame
CAS:<p>Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.</p>Fórmula:C10H14N2O4S2Pureza:99.91%Cor e Forma:SolidPeso molecular:290.36Crobenetine
CAS:<p>Crobenetine (BIII 890 CL) Free Base is a selective NaV channel blocker that eliminates VTD-induced [Ca2+] elevation.</p>Fórmula:C25H33NO2Pureza:98.99%Cor e Forma:SolidPeso molecular:379.54Carbazeran
CAS:<p>Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases.</p>Fórmula:C18H24N4O4Pureza:99.3%Cor e Forma:SolidPeso molecular:360.41Utreloxastat
CAS:<p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>Fórmula:C18H28O2Pureza:99.95%Cor e Forma:SolidPeso molecular:276.41IHVR-17028
CAS:<p>IHVR-17028 is a potent broad-spectrum ERα-glucosidase I (α-glucosidase? I) inhibitor with IC50 of 0.24 μM and antiviral activity.</p>Fórmula:C23H44N2O5Pureza:97.90%Cor e Forma:SolidPeso molecular:428.61K-111
CAS:<p>K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.</p>Fórmula:C18H25Cl3O2Pureza:99.64% - 99.88%Cor e Forma:SolidPeso molecular:379.75NG-497
CAS:<p>NG-497, a selective inhibitor of human ATGL, blocks lipolysis in adipocytes and aids cancer research.</p>Fórmula:C18H21NO4Pureza:99.56%Cor e Forma:SolidPeso molecular:315.36MM 11253
CAS:<p>MM 11253 is a RARγ antagonist with IC50 of 44nM.</p>Fórmula:C28H30O2S2Pureza:99.41%Cor e Forma:SolidPeso molecular:462.67Lauroyl lysine
CAS:<p>Lauroyl lysine (N6-Lauroyl-L-lysine) functions as skin and hair conditioning agents and as surfactants-cleansing agents in personal care products.</p>Fórmula:C18H36N2O3Pureza:99.18%Cor e Forma:White To Off-White Solid With Characteristic Faint OdorPeso molecular:328.49Tamolarizine
CAS:<p>Tamolarizine (Tamolarizine free base) free base is a novel calcium antagonist.</p>Fórmula:C27H32N2O3Pureza:98.17%Cor e Forma:SoildPeso molecular:432.55Carbonic anhydrase inhibitor 6
CAS:<p>Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.</p>Fórmula:C26H25N3O5SPureza:98.81%Cor e Forma:SolidPeso molecular:491.56Cholesterol 24-hydroxylase-IN-1
CAS:<p>Cholesterol 24-hydroxylase-IN-1 is a cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor used in the study of neurological disorders such as epilepsy.</p>Fórmula:C17H23N5OPureza:98.42%Cor e Forma:SolidPeso molecular:313.40BRD7389
CAS:<p>BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.</p>Fórmula:C24H18N2O2Pureza:99.51%Cor e Forma:SolidPeso molecular:366.41Salnacedin
CAS:<p>Salnacedin (G-201) treats immune, skin, and musculoskeletal issues, suitable for acne, dermatitis, and psoriasis research.</p>Fórmula:C12H13NO5SPureza:99.13%Cor e Forma:SolidPeso molecular:283.3Ladostigil
CAS:<p>Ladostigil is an oral cholinesterase & MAO-B inhibitor used for depression and Alzheimer's studies.</p>Fórmula:C16H20N2O2Pureza:97.48%Cor e Forma:SolidPeso molecular:272.34Imigliptin
CAS:<p>Imigliptin Dihydrochloride, a selective dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type II diabetes.</p>Fórmula:C21H24N6OPureza:99.12%Cor e Forma:SolidPeso molecular:376.46HSD-016
CAS:<p>HSD-016: Oral 11β-HSD1 inhibitor, active in humans, mice, rats (IC50: 11, 1, 8 nM), potential for type 2 diabetes research.</p>Fórmula:C21H21F7N2O3SPureza:99.40% - >99.99%Cor e Forma:SolidPeso molecular:514.46Lidorestat
CAS:<p>Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity.</p>Fórmula:C18H11F3N2O2SPureza:99.98%Cor e Forma:SolidPeso molecular:376.3511-cis-Vaccenyl acetate
CAS:<p>11-cis-Vaccenyl acetate ((Z)-Octadec-11-enyl acetate) activates olfactory neurons located in the T1 sensilla on the antenna and mediates aggregation behavior in</p>Fórmula:C20H38O2Pureza:96.53% - 99.95%Cor e Forma:LiquidPeso molecular:310.51BAY-0069
CAS:<p>BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be</p>Fórmula:C22H16BrN3O4Pureza:99.41%Cor e Forma:SoildPeso molecular:466.28Malic enzyme inhibitor ME1
CAS:<p>Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.</p>Fórmula:C20H21N3O3Pureza:99.84%Cor e Forma:SolidPeso molecular:351.4S-2474
CAS:<p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>Fórmula:C20H31NO3SPureza:99.03%Cor e Forma:SolidPeso molecular:365.53AChE/BChE/MAO-B-IN-1
CAS:<p>AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects</p>Fórmula:C20H24N2O2Pureza:98.17%Cor e Forma:SolidPeso molecular:324.42PC945
CAS:<p>PC945 (Opelconazole) is an antifungal compound that inhibits CYP51A/CYP51B and can be used to study fungal infections of the lungs.</p>Fórmula:C38H37F3N6O3Pureza:98.89% - 99.37%Cor e Forma:SolidPeso molecular:682.73Fenoverine
CAS:<p>Fenoverine (Spasmopriv) has antispasmodic activity and can be used to study gastrointestinal spasms.</p>Fórmula:C26H25N3O3SPureza:98.34%Cor e Forma:SolidPeso molecular:459.56AC-261066
CAS:<p>AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.</p>Fórmula:C17H20FNO4SPureza:99.64%Cor e Forma:SolidPeso molecular:353.41Ulodesine
CAS:<p>Ulodesine (BCX4208), a PNP inhibitor, has an IC50 of 2.293 nM/L, potentially useful for hyperuricaemia research.</p>Fórmula:C12H16N4O3Pureza:99.68%Cor e Forma:SoildPeso molecular:264.284-Hydroxymephenytoin
CAS:<p>4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.</p>Fórmula:C12H14N2O3Pureza:99.78%Cor e Forma:SolidPeso molecular:234.25KT203
CAS:<p>KT203 is an α/β hydrolase structural domain 6 (ABHD6) inhibitor with potential antiviral and anti-inflammatory activity for the study of pneumonia.</p>Fórmula:C28H26N4O3Pureza:98.51%Cor e Forma:SolidPeso molecular:466.53PTP1B-IN-3
CAS:<p>PTP1B-IN-3 是一种具有有选择性和高效性的 PTP1B 抑制剂，具有抗癌活性，抑制 PTP1B 和 TCPTP 。PTP1B-IN-3 可用于研究糖尿病。</p>Fórmula:C12H7BrF2NO3PPureza:99.31% - 99.97%Cor e Forma:SolidPeso molecular:362.06CERM-11956
CAS:<p>Pelretin (BASF 43915) is a potential protein inhibitor for the study of dermatologic diseases.</p>Fórmula:C29H38N2O7Pureza:99.38%Cor e Forma:SolidPeso molecular:526.62Verofylline
CAS:<p>Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for the</p>Fórmula:C12H18N4O2Pureza:98.33% - 98.83%Cor e Forma:SolidPeso molecular:250.3KLH45
CAS:<p>KLH45 is an effective and selective inhibitor of Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2(IC50 = 1.3 nM).</p>Fórmula:C24H25F3N4O2Pureza:99.61%Cor e Forma:SolidPeso molecular:458.48UCM05
CAS:<p>UCM05 is a potent FASN and FtsZ inhibitor active against HER2+ breast cancer and B. subtilis (MIC 100 μM), but not E. coli.</p>Fórmula:C24H16O10Pureza:99.25%Cor e Forma:SolidPeso molecular:464.38DS16570511
CAS:<p>DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter.</p>Fórmula:C30H25Cl2N3O4Pureza:98.34% - 98.45%Cor e Forma:SolidPeso molecular:562.44uk-50001
CAS:<p>UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.</p>Fórmula:C26H24F3N3O4Pureza:99.90%Cor e Forma:SolidPeso molecular:499.48SERCA2a activator 1
CAS:<p>SERCA2a activator 1 boosts heart function by reducing phospholamban restraint and enhancing cardiac contraction-relaxation cycles.</p>Fórmula:C32H29N3O4SPureza:99.75%Cor e Forma:SolidPeso molecular:551.66AZD-0284
CAS:<p>AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].</p>Fórmula:C21H18F6N2O5SPureza:99.82%Cor e Forma:SolidPeso molecular:524.43Clopimozide
CAS:<p>Clopimozide (R-29764), a long-acting oral antischizophrenic, blocks calcium channels and [3H] nilandipine binding.</p>Fórmula:C28H28ClF2N3OPureza:98.19% - >99.99%Cor e Forma:SolidPeso molecular:495.99KT182
CAS:<p>KT182 is a selective and potent inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.</p>Fórmula:C27H26N4O2Pureza:99.66%Cor e Forma:SolidPeso molecular:438.52NecroX-5
CAS:<p>NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.</p>Fórmula:C27H39N3O9S3Pureza:99.944%Cor e Forma:SolidPeso molecular:645.81PDE4B-IN-2
CAS:<p>PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.</p>Fórmula:C19H18ClN3O2SPureza:99.32%Cor e Forma:SolidPeso molecular:387.88Acetyl-L-carnitine
CAS:<p>Acetyl-L-carnitine, an amino-acid supplement, crosses the blood-brain barrier to aid in neuroinflammation and Alzheimer's.</p>Fórmula:C9H17NO4Pureza:>99.99%Cor e Forma:SolidPeso molecular:203.24Diproteverine HCl
CAS:<p>Diproteverine HCl is a novel calcium antagonist with antianginal properties, antispasmodic and vasoactive.</p>Fórmula:C26H36ClNO4Pureza:98.55% - 99.84%Cor e Forma:SolidPeso molecular:462.02LDL-IN-3
CAS:<p>LDL-IN-3 shows anti-atherosclerotic and antioxidant activities.</p>Fórmula:C24H36O3SiPureza:99.75%Cor e Forma:SolidPeso molecular:400.63Nanterinone
CAS:<p>Nanterinone: oral phosphodiesterase inhibitor, improves acute heart failure hemodynamics.</p>Fórmula:C15H15N3OPureza:99.53%Cor e Forma:SolidPeso molecular:253.3Nampt activator-2
CAS:<p>Nampt activator-2: Potent NAMPT activator (EC50: 0.023 μM), binds CYP2C9 (0.060 μM), 2D6 (0.41 μM), 2C19 (0.59 μM); useful in metabolic disease research.</p>Fórmula:C17H15ClN4O3SPureza:98.30% - 98.33%Cor e Forma:SolidPeso molecular:390.84TDO-IN-1
CAS:<p>TDO-IN-1 is a tryptophan 2,3-dioxygenase (TDO) inhibitor with antitumor activity that acts by reversing local immune tolerance in tumor tissues.</p>Fórmula:C16H13F3N4O2Pureza:99.86%Cor e Forma:SolidPeso molecular:350.3PF-04447943
CAS:<p>PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.</p>Fórmula:C20H25N7O2Pureza:99.36% - 99.59%Cor e Forma:SolidPeso molecular:395.46CM037
CAS:<p>CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminate</p>Fórmula:C21H25N3O3S2Pureza:99.34%Cor e Forma:SolidPeso molecular:431.57CYP1B1-IN-4
CAS:<p>CYP1B1-IN-4: 2,4-diarylthiazole, selective CYP1B1 inhibitor (IC50=0.2 nM), low cytotoxicity, stable in liver microsomes.</p>Fórmula:C18H14N2O2SPureza:98.74%Cor e Forma:SolidPeso molecular:322.38Atibeprone
CAS:<p>Atibeprone is a MAO-B inhibitor with antidepressant activity for the study of Parkinson's disease.</p>Fórmula:C17H18N2O3SPureza:99.18% - 99.86%Cor e Forma:SolidPeso molecular:330.4C75
CAS:<p>C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).</p>Fórmula:C14H22O4Pureza:98.84% - >99.99%Cor e Forma:SolidPeso molecular:254.32PHGDH-IN-3
CAS:<p>PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.</p>Fórmula:C24H18FN3O4S2Pureza:97.24% - 98.55%Cor e Forma:SolidPeso molecular:495.55EWP 815
CAS:<p>EWP 815, a disulfiram analog, inhibits Ins(1,4)P2, Ins(1,4,5)P3 phosphatases, and dopamine β-hydroxylase.</p>Fórmula:C12H22N4S4Pureza:98%Cor e Forma:SolidPeso molecular:350.59EMD-503982
CAS:<p>EMD-503982 is a potential Factor Xa and Factor VIIa inhibitor with anticancer activity for the study of thromboembolic and neurologic diseases.</p>Fórmula:C22H23ClN4O5Pureza:97.09% - 99.81%Cor e Forma:SolidPeso molecular:458.90MK-0873
CAS:<p>MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.</p>Fórmula:C25H18N4O3Pureza:98.40%Cor e Forma:SolidPeso molecular:422.44Bupicomide
CAS:<p>Bupicomide is a dopamine β-hydroxylase inhibitor with antihypertensive and vasodilatory activity and may be used in the study of hypertension.</p>Fórmula:C10H14N2OPureza:99.84% - >99.99%Cor e Forma:SolidPeso molecular:178.23Mopidamol
CAS:<p>Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental</p>Fórmula:C19H31N7O4Pureza:99.05% - 99.78%Cor e Forma:SolidPeso molecular:421.49LY 517717
CAS:<p>LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).</p>Fórmula:C27H33N5O2Pureza:99.77% - 99.88%Cor e Forma:SolidPeso molecular:459.58KRH102140
CAS:<p>KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.</p>Fórmula:C25H24FNOPureza:98.31% - 99.61%Cor e Forma:SolidPeso molecular:373.46JNJ-DGAT2-A
CAS:<p>JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.</p>Fórmula:C24H16BrFN4O2SPureza:98.3%Cor e Forma:SolidPeso molecular:523.38AWD 12-281
CAS:<p>AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).</p>Fórmula:C22H14Cl2FN3O3Pureza:99.25% - 99.85%Cor e Forma:SolidPeso molecular:458.27Fidexaban
CAS:<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Fórmula:C25H24F2N6O5Pureza:98.64% - 99.43%Cor e Forma:SolidPeso molecular:526.49OSMI-4
CAS:<p>OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor that can be used to study OGT inhibition in different human cell lines.Cost-effective and quality-assured.</p>Fórmula:C27H26ClN3O7S2Pureza:99.68%Cor e Forma:SolidPeso molecular:604.09Isolithocholic Acid
CAS:<p>Isolithocholic Acid, a bile acid isomer, forms through microbial metabolism of Lithocholic acid or its 3α-sulfate.</p>Fórmula:C24H40O3Pureza:99.56% - 99.84%Cor e Forma:SolidPeso molecular:376.57PKUMDL-WQ-2101
CAS:<p>PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.</p>Fórmula:C14H11N3O6Pureza:99.57%Cor e Forma:SolidPeso molecular:317.25Vatanidipine
CAS:<p>Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting</p>Fórmula:C41H42N4O6Pureza:99.95%Cor e Forma:SolidPeso molecular:686.8JNJ-42226314
CAS:<p>JNJ-42226314 is a MAGL inhibitor with anti-injury effects and has shown efficacy in neuropathic pain and inflammatory pain models.</p>Fórmula:C26H24FN5O2SPureza:99.62%Cor e Forma:SolidPeso molecular:489.56Indeglitazar
CAS:<p>Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).</p>Fórmula:C19H19NO6SPureza:99.45%Cor e Forma:SolidPeso molecular:389.42ML 209
CAS:<p>ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription</p>Fórmula:C25H31NO6Pureza:99.87%Cor e Forma:SolidPeso molecular:441.52Zifaxaban
CAS:<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Fórmula:C20H16ClN3O4SPureza:97.46% - 99.82%Cor e Forma:SolidPeso molecular:429.88BPDA2
CAS:<p>BPDA2 selectively inhibits SHP2 (IC50=92nM) over SHP1/1B (33.39/40.71μM), curbs RTKs, and hampers SHP2-driven breast cancer cell traits.</p>Fórmula:C24H30O5Pureza:99.80%Cor e Forma:SolidPeso molecular:398.49PBRM
CAS:<p>PBRM (17β-HSD1-IN-2) is a selective covalent inhibitor of 17β-HSD1, used in breast cancer and endometriosis research.</p>Fórmula:C28H34BrNO2Pureza:99.56% - 99.59%Cor e Forma:SolidPeso molecular:496.48HTS07545
CAS:<p>HTS07545, an SQOR inhibitor (IC50: 30nM), slows H2S breakdown, researched for heart failure.</p>Fórmula:C22H18N2O3Pureza:99.71%Cor e Forma:SolidPeso molecular:358.39Dovramilast
CAS:<p>Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.</p>Fórmula:C24H28N2O6SPureza:98.75% - 99.62%Cor e Forma:SolidPeso molecular:472.55PKUMDL-LC-101-D04
CAS:<p>PKUMDL-LC-101-D04 enhances GPX4, curbs iron death, boosts enzyme activity 150% at 20 μM, effective in wild-type MEF, reduces lipid peroxide toxicity.</p>Fórmula:C14H23ClN4O2S2Pureza:98.71%Cor e Forma:SolidPeso molecular:378.94PKM2 activator 2
CAS:<p>PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuates</p>Fórmula:C20H18F2N2O4S2Pureza:99.92%Cor e Forma:SolidPeso molecular:452.49BMS-823778
CAS:<p>BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.</p>Fórmula:C18H18ClN3OPureza:99.39% - 99.75%Cor e Forma:SolidPeso molecular:327.81NCGC 607
CAS:<p>NCGC 607 is a a noninhibitory chaperone of glucocerebrosidase (GCase).</p>Fórmula:C24H22IN3O4Pureza:99.69%Cor e Forma:SolidPeso molecular:543.35SR2211
CAS:<p>SR2211 is a specific modulator and an inverse agonist of RORγ(IC50 = 320 nM, Ki = 105 nM).</p>Fórmula:C26H24F7N3OPureza:98.75%Cor e Forma:SolidPeso molecular:527.48Giripladib
CAS:<p>Giripladib (PLA695/PLX-695) blocks radiation-boosted phosphorylation of ERK and Akt in endothelial cells.</p>Fórmula:C41H36ClF3N2O4SPureza:99.64%Cor e Forma:SolidPeso molecular:745.25Tigulixostat
CAS:<p>Tigulixostat (LC350189) is a novel xanthine oxidase inhibitor (XOI) that reduces uric acid production and may be used to study gout-related diseases.</p>Fórmula:C16H14N4O2Pureza:98.22% - 99.71%Cor e Forma:SolidPeso molecular:294.315-LOX-IN-1
CAS:<p>5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.</p>Fórmula:C20H18N2O2SPureza:97.45%Cor e Forma:SolidPeso molecular:350.43Orellanine
CAS:<p>Orellanine, from Cortinarius orellanus, is nephrotoxic and hinders macromolecule synthesis in kidney cells and liver mitochondria.</p>Fórmula:C10H8N2O6Pureza:99.66%Cor e Forma:SolidPeso molecular:252.18JJKK 048
CAS:<p>JJKK 048 is a potent and selective MAGL inhibitor.</p>Fórmula:C23H22N4O5Pureza:99.77%Cor e Forma:SolidPeso molecular:434.44L-Threonine derivative-1
CAS:<p>L-Threonine derivative-1 is acetylsalicylic acid-L-threonine ester with potential analgesic activity.</p>Fórmula:C13H15NO6Pureza:97.03% - 98.91%Cor e Forma:SolidPeso molecular:281.26AMG-1694
CAS:<p>AMG-1694 disrupts GK-GKRP complex, enhancing GK activity with 7 nM IC50; normalizes glucose in diabetic rodents without affecting normoglycemic animals.</p>Fórmula:C23H30F3N3O4S2Pureza:98.37%Cor e Forma:SolidPeso molecular:533.63hCAI/II-IN-6
CAS:<p>hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).</p>Fórmula:C19H24N4O3SPureza:97.07%Cor e Forma:SolidPeso molecular:388.48Chloramphenicol succinate
CAS:<p>Chloramphenicol succinate is a bacteriostatic antibiotic. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH),can be oxidized by.</p>Fórmula:C15H16Cl2N2O8Pureza:95.32%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:423.2Pradefovir
CAS:<p>Pradefovir (Remofovir) is a prodrug for chronic HBV, converting to PMEA in the liver with a Km of 60 μM and clearance of 359 ml/min.</p>Fórmula:C17H19ClN5O4PPureza:97.50%Cor e Forma:SolidPeso molecular:423.79Izonsteride
CAS:<p>Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride is</p>Fórmula:C24H26N2OS2Pureza:99.55%Cor e Forma:SolidPeso molecular:422.61Tofimilast
CAS:<p>Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.</p>Fórmula:C18H21N5SPureza:99.55%Cor e Forma:SolidPeso molecular:339.46alphaSYN-IN-NAB2
CAS:<p>alphaSYN-IN-NAB2: a NAB2 gene protein guarding neurons against alpha-SYN harm; aids endosomal transport, cell processes, and can study various diseases.</p>Fórmula:C23H20ClN3OPureza:98.49%Cor e Forma:SolidPeso molecular:389.88Lecimibide
CAS:<p>Lecimibide (DuP 128) is a potent and selective inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT), which can be used to study diseases due to high</p>Fórmula:C34H40F2N4OSPureza:99.44% - 99.87%Cor e Forma:SolidPeso molecular:590.77hCAII-IN-9
CAS:<p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>Fórmula:C15H16ClN3O5S2Pureza:98.63%Cor e Forma:SolidPeso molecular:417.89Dasantafil
CAS:<p>Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.</p>Fórmula:C22H28BrN5O5Pureza:99.4% - 99.50%Cor e Forma:SolidPeso molecular:522.39Xanthine oxidoreductase-IN-3
CAS:<p>Xanthine oxidoreductase-IN-3, an oral XOR inhibitor with IC50 of 26.3 nM, is useful for acute hyperuricemia research.</p>Fórmula:C14H10ClN5OPureza:98.1%Cor e Forma:SolidPeso molecular:299.72NAAD sodium salt
CAS:<p>NAAD sodium salt (NAAD Na salt) is a substrate of nicotinamide adenine dinucleotide synthase and can be used in studies about the specificity and kinetics of</p>Fórmula:C21H25N6NaO15P2Pureza:98.6% - 99.87%Cor e Forma:SolidPeso molecular:686.4Cronidipine
CAS:<p>Cronidipine (LF 20254), a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.</p>Fórmula:C30H32ClN3O8Pureza:99.47%Cor e Forma:SolidPeso molecular:598.04Imanixil
CAS:<p>Imanixil boosts LDLR, cuts cholesterol and VLDL production, reducing atherosclerosis.</p>Fórmula:C17H17F3N6O2Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:394.35Lifarizine
CAS:<p>Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion.</p>Fórmula:C29H32N4Pureza:99.88%Cor e Forma:SolidPeso molecular:436.59MAO-B-IN-8
CAS:<p>MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of</p>Fórmula:C18H16O6Pureza:99.62%Cor e Forma:SolidPeso molecular:328.32BMS 753
CAS:<p>BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).</p>Fórmula:C21H21NO4Pureza:98.55%Cor e Forma:SolidPeso molecular:351.4SBI-425
CAS:<p>SBI-425: orally available TNAP inhibitor, enhances cardiovascular health & survival, no bone impact.</p>Fórmula:C13H12ClN3O4SPureza:99.88%Cor e Forma:SolidPeso molecular:341.77Aleplasinin
CAS:<p>Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic</p>Fórmula:C28H27NO3Pureza:99.21%Cor e Forma:SolidPeso molecular:425.52Esuprone
CAS:<p>Esuprone (LU-43839) is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.</p>Fórmula:C13H14O5SPureza:99.45%Cor e Forma:SolidPeso molecular:282.31NNC 05-2090 hydrochloride
CAS:<p>NNC 05-2090 HCl: BGT-1 inhibitor, IC50 = 10.6 μM, potential for epilepsy, neurological research.</p>Fórmula:C27H31ClN2O2Pureza:99.05%Cor e Forma:SolidPeso molecular:451Ibiglustat (L-Malic acid)
CAS:<p>Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase.</p>Fórmula:C24H30FN3O7SPureza:99.54%Cor e Forma:SolidPeso molecular:523.57Phosphatase-IN-1
CAS:<p>Phosphatase-IN-1 is a phosphatidic acid phosphatase (Pah) inhibitor with antifungal activity for the study of rice blast and ruderalia.</p>Fórmula:C16H16Cl2FNO2Pureza:99.88%Cor e Forma:SolidPeso molecular:344.21Tiapamil hydrochloride
CAS:<p>Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity used in the study of angina pectoris.</p>Fórmula:C26H38ClNO8S2Pureza:99.17%Cor e Forma:SolidPeso molecular:592.16MM-433593
CAS:<p>MM-433593 is a selective fatty acid amide hydrolase (FAAH-1) inhibitor for the treatment of pain, inflammation, and other disorders.</p>Fórmula:C25H22ClN3O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:447.91GSK205
CAS:<p>GSK205 is a selective TRPV4 antagonist (IC50: 4.19 μM) for inhibiting TRPV4-mediated Ca2+ influx.</p>Fórmula:C24H25BrN4SPureza:99.46%Cor e Forma:SolidPeso molecular:481.45sEH inhibitor-7
CAS:<p>sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively.</p>Fórmula:C15H21NO2Pureza:99.56%Cor e Forma:SolidPeso molecular:247.33CYP4A11/CYP4F2-IN-1
CAS:<p>CYP4A11/CYP4F2-IN-1 is a cytochrome P450 (CYP) 4A11 and CYP4F2 inhibitor for the study of kidney disease and cardiovascular disease.</p>Fórmula:C15H15N3OSPureza:99.75%Cor e Forma:SolidPeso molecular:285.36Allopurinol riboside
CAS:<p>Allopurinol riboside, an allopurinol metabolite, inhibits purine nucleoside phosphorylase in parasites with a Ki of 277 μM.</p>Fórmula:C10H12N4O5Pureza:99.46% - 99.73%Cor e Forma:SolidPeso molecular:268.23MLS000544460
CAS:<p>MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2</p>Fórmula:C17H12FN3O2SPureza:99.72%Cor e Forma:SolidPeso molecular:341.36Farglitazar
CAS:<p>Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.</p>Fórmula:C34H30N2O5Pureza:99.4% - 99.52%Cor e Forma:SolidPeso molecular:546.615-ALA benzyl ester hydrochloride
CAS:<p>5-ALA benzyl ester hydrochloride: a photodetection agent that promotes PPIX in colon cancer cells.</p>Fórmula:C12H16ClNO3Pureza:98.39% - 99.38%Cor e Forma:SolidPeso molecular:257.71ARRY-403
CAS:<p>ARRY-403 is a novel glucokinase activator that reduces fasting and postprandial blood glucose in patients with type 2 diabetes.</p>Fórmula:C20H18N6O3S2Pureza:98.80%Cor e Forma:SolidPeso molecular:454.52JNJ-40355003
CAS:<p>JNJ-40355003 is a FAAH inhibitor that increases plasma levels of fatty acid amides in rats, dogs, and crabs.</p>Fórmula:C23H23ClN4O2Pureza:99.32%Cor e Forma:SolidPeso molecular:422.91MY10
CAS:<p>MY10, a potent and orally active inhibitor of the receptor protein tyrosine phosphatase (RPTPβ/ζ), effectively reduces binge-like ethanol consumption and</p>Fórmula:C15H10F6OS2Pureza:98.64%Cor e Forma:SolidPeso molecular:384.36AICAR monophosphate
CAS:<p>AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.</p>Fórmula:C9H15N4O8PPureza:99.8%Cor e Forma:SolidPeso molecular:338.21AGN 196996
CAS:<p>AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).</p>Fórmula:C24H20BrNO5Pureza:98.74%Cor e Forma:SolidPeso molecular:482.32Dalvastatin
CAS:<p>Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepatic</p>Fórmula:C24H31FO3Pureza:98.80%Cor e Forma:SolidPeso molecular:386.5AZ3976
CAS:<p>AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.</p>Fórmula:C15H19N5O3Pureza:98.14%Cor e Forma:SolidPeso molecular:317.34Xanthine oxidoreductase-IN-5
CAS:<p>Xanthine oxidoreductase-IN-5: oral XOR inhibitor; IC50 55 nM; for acute hyperuricemia research.</p>Fórmula:C17H17N5O2Pureza:99.21%Cor e Forma:SolidPeso molecular:323.35Rbin-2
CAS:<p>Rbin-2: Potent, selective Midasin inhibitor; reversible, cell-permeable; halts eukaryotic ribosome assembly.</p>Fórmula:C13H11BrN4SPureza:98.75%Cor e Forma:SolidPeso molecular:335.22CX-157
CAS:<p>CX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer.</p>Fórmula:C14H8F4O4SPureza:99.35%Cor e Forma:SolidPeso molecular:348.27PD173212
CAS:<p>PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2).</p>Fórmula:C38H53N3O3Pureza:99.84%Cor e Forma:SolidPeso molecular:599.85Opc 8490
CAS:<p>Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator, which prolongs the atrial action potential in a concentration-dependent manner.</p>Fórmula:C30H35N3O10Pureza:98.88%Cor e Forma:SolidPeso molecular:597.61IPN60090
CAS:<p>IPN60090: potent oral GLS1 inhibitor, IC50 of 31 nM, potential for anticancer and immunomodulation.</p>Fórmula:C24H27F3N8O3Pureza:99.76%Cor e Forma:SolidPeso molecular:532.52RPR107393 free base
CAS:<p>NVP-BAG956 (BAG956) is a PI3K/PDK inhibitor that inhibits PI3Kδ, and can be used to study melanoma.</p>Fórmula:C22H22N2OPureza:99.13% - 99.57%Cor e Forma:SolidPeso molecular:330.42AA 2379
CAS:<p>N6-Allyladenosine (N Allyladenosine) is a nucleoside analog with antimicrobial activity and anticancer activity.</p>Fórmula:C15H23N5O4Pureza:97.78% - 98.87%Cor e Forma:SolidPeso molecular:337.37(R)-IDO/TDO-IN-1
CAS:<p>(R)-IDO/TDO-IN-1 (compound 25), an indoleamine-2,3-dioxygenase (IDO) inhibitor, demonstrates good pharmacokinetic properties and exerts anti-tumor effects in the MC38 xenograft model. This compound exhibits synergy when combined with the anti-PD-1 monoclonal antibody (SHR-1210) [1].</p>Fórmula:C25H24FN5Cor e Forma:SolidPeso molecular:413.498-Hydroxyguanine hydrochloride
CAS:<p>8-Hydroxyguanine, generated through the oxidative degradation of DNA by the hydroxyl radical, serves as an indicator of oxidative stress in biological systems.</p>Fórmula:C5H5N5O2HClCor e Forma:SolidPeso molecular:203.615-PGDH-IN-1
CAS:<p>15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.</p>Fórmula:C24H22N4O2Cor e Forma:SolidPeso molecular:398.46Celgosivir
CAS:<p>Celgosivir (6 O-butanoyl castanospermine) is an inhibitor of α-glucosidase I. In vitro assay, it inhibits bovine viral diarrhoea virus (BVDV) ( IC50: 1.27 μM ).</p>Fórmula:C12H21NO5Pureza:98.03%Cor e Forma:SolidPeso molecular:259.3ICMT-IN-17
CAS:<p>ICMT-IN-17 (compound 52) serves as an ICMT inhibitor, exhibiting an IC50 value of 0.38 μM [1].</p>Fórmula:C22H26F3NOCor e Forma:SolidPeso molecular:377.44PF-915275
CAS:<p>PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.</p>Fórmula:C18H14N4O2SPureza:99.58% - 99.61%Cor e Forma:SolidPeso molecular:350.39BIO-32546
CAS:<p>BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.</p>Fórmula:C28H31F6NO3Pureza:98.03%Cor e Forma:SolidPeso molecular:543.54γ-CEHC
CAS:<p>γ-CEHC, a metabolite of γ-tocopherol, is predominantly excreted through urine, primarily in its conjugated form as glucuronide [1], rather than through bile.</p>Fórmula:C15H20O4Cor e Forma:SolidPeso molecular:264.32Ac-VDVAD-CHO
CAS:<p>Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].</p>Fórmula:C23H37N5O10Pureza:98%Cor e Forma:SolidPeso molecular:543.57Gisadenafil besylate
CAS:<p>Gisadenafil besylate (UK 369003-26) is a potent and orally active PDE5 inhibitor, for lower urinary tract symptoms associated with benign prostatic hyperplasia.</p>Fórmula:C29H39N7O8S2Cor e Forma:SolidPeso molecular:677.79GSK2324
CAS:<p>GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.</p>Fórmula:C29H22Cl2N2O4Pureza:98.09% - 99.02%Cor e Forma:SolidPeso molecular:533.4N-Lignoceroyl Taurine
CAS:<p>N-Acyl taurines, such as N-lignoceroyl taurine, alongside various arachidonoyl amino acid conjugates like N-arachidonoyl dopamine and N-arachidonoyl-L-serine, have been identified in bovine brain and through mass spectrometry lipidomic studies in the brain and spinal cord of both wild-type and FAAH knockout mice. Notably, N-lignoceroyl taurine levels were found to be 23-26 times higher in FAAH knockout mice than in wild types, suggesting its degradation by FAAH, despite in vitro evidence showing FAAH hydrolyzes N-lignoceroyl taurine significantly slower than oleoyl ethanolamide. Additionally, N-acyl taurines with polyunsaturated acyl chains are known to activate TRPV1 and TRPV4 channels within the transient receptor potential (TRP) family of calcium channels.</p>Fórmula:C26H53NO4SCor e Forma:SolidPeso molecular:475.81,2-Dinonadecanoyl-sn-glycero-3-PC
CAS:<p>1,2-Dinonadecanoyl-sn-glycero-3-PC (DNPC), a saturated phospholipid, serves as a standard in quantifying phosphatidylcholines in human synovial fluid and has been utilized in researching lipid bilayer phase transition dynamics.</p>Fórmula:C46H92NO8PCor e Forma:SolidPeso molecular:818.21513,14-dihydro-15(R)-Prostaglandin E1
CAS:<p>13,14-Dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)-PGE1) is an analog of 13,14-dihydro-PGE1 characterized by its R-configured hydroxyl group at the C-15 position [1].</p>Fórmula:C20H36O5Cor e Forma:SolidPeso molecular:356.503ICMT-IN-6
CAS:<p>ICMT-IN-6 (compound 29) serves as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an inhibitory concentration 50 (IC50) value of</p>Fórmula:C23H31NO2Cor e Forma:SolidPeso molecular:353.5AR453588
CAS:<p>AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H25N7O2S2Cor e Forma:SolidPeso molecular:519.64ICMT-IN-34
CAS:<p>ICMT-IN-34 (compound 39) serves as an effective inhibitor of ICMT, exhibiting an IC50 value of 0.17 μM [1].</p>Fórmula:C21H25Cl2NOCor e Forma:SolidPeso molecular:378.3413-OAHSA
CAS:<p>13-OAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), results from the esterification of oleic acid to 13-hydroxy stearic acid. It represents a significant component of the FAHFA family, most abundantly expressed in the serum of glucose-tolerant AG4OX mice that exhibit adipose tissue-specific overexpression of the Glut4 glucose transporter. Similar to other FAHFAs which are known to enhance glucose tolerance, stimulate insulin secretion, and exert anti-inflammatory effects, 13-OAHSA may play a pivotal role in managing metabolic syndrome and inflammation.</p>Fórmula:C36H68O4Cor e Forma:SolidPeso molecular:564.9FXIa-IN-7
CAS:<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Fórmula:C28H28N2O4Pureza:98.55%Cor e Forma:SolidPeso molecular:456.53VU0155069 hydrochloride
CAS:<p>VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent and selective inhibitor of phospholipase D (PLD), exhibiting IC50 values of 46 nM for PLD1 and 933 nM for PLD2. It effectively inhibits the migration of both human and mouse breast cancer cell lines [1] [2].</p>Fórmula:C26H28Cl2N4O2Cor e Forma:SolidPeso molecular:499.43cKK-E15
CAS:<p>cKK-E15, a peptide-lipid, is instrumental in formulating LNP3 alongside C14PEG2000, unmodified cholesterol, and DOPE [1].</p>Fórmula:C72H144N4O6Cor e Forma:SolidPeso molecular:1161.94Oseltamivir acid methyl ester
CAS:<p>Oseltamivir acid methyl ester, a CES1-convertible neuraminidase inhibitor, serves as an antiviral prodrug.</p>Fórmula:C15H26N2O4Pureza:98.78%Cor e Forma:SolidPeso molecular:298.38C12-113
CAS:<p>C12-113, a lipidoid delivery agent, effectively transfects siRNA into cells and, when combined with additional lipids, forms lipid nanoparticles (LNPs). These LNPs facilitate the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice [1] [2].</p>Fórmula:C53H111N3O4Cor e Forma:SolidPeso molecular:854.47GSK2647544
CAS:<p>GSK2647544 inhibits Lp-PLA2, a pro-inflammatory enzyme from macrophages, orally active, calcium-independent.</p>Fórmula:C24H18ClF3N4O3Cor e Forma:SolidPeso molecular:502.8714,15-Epoxyeicosatrienoic acid
CAS:<p>14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.471-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol
CAS:<p>1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol, a triacylglycerol, features myristic acid, linoleic acid, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. This compound is prevalent in mature human milk, infant formula fats, and butterfat.</p>Fórmula:C53H96O6Cor e Forma:SolidPeso molecular:829.33FR-234938
CAS:<p>FR-234938 is a non-nucleoside adenosine deaminase inhibitor with anti-inflammatory activity.</p>Fórmula:C19H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:323.39XR3054
CAS:<p>XR3054 is a farnesyl protein transferase inhibitor that blocks proliferation in certain cancer cells, not dependent on ras mutation status.</p>Fórmula:C13H22O2Cor e Forma:SolidPeso molecular:210.31JNJ-40929837
CAS:<p>JNJ-40929837 is an oral inhibitor of LTA4 hydrolase, which catalyzes LTB4 production.</p>Fórmula:C22H24N4O2SCor e Forma:SolidPeso molecular:408.521,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE
CAS:<p>1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.</p>Fórmula:C39H78NO8PCor e Forma:SolidPeso molecular:720.026GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Fórmula:C21H24F3N7OPureza:99.86% - 99.86%Cor e Forma:SolidPeso molecular:447.46Prolyl Hydroxylase inhibitor 1
CAS:<p>Prolyl Hydroxylase inhibitor 1 is an orally active inhibitor of hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) (IC50 of 62.23 nM).</p>Fórmula:C19H18ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:415.831-Palmitoyl-3-Stearoyl-rac-glycerol
CAS:<p>1-Palmitoyl-3-stearoyl-rac-glycerol, a diacylglycerol, features palmitic acid at the sn-1 position and stearic acid at the sn-3 position. This compound appears in palm-based diacylglycerols derived from palm stearin, palm mid fraction, palm oil, and palm olein, as well as in extracts of wheat bran and brewer's spent grain.</p>Fórmula:C37H72O5Cor e Forma:SolidPeso molecular:596.96ICMT-IN-12
CAS:<p>ICMT-IN-12 (compound 78) serves as an ICMT inhibitor, demonstrating an IC50 value of 0.42 μM [1].</p>Fórmula:C24H33NOSCor e Forma:SolidPeso molecular:383.59SHP2-IN-21
CAS:<p>SHP2-IN-21 (compound 208) is an inhibitor of SHP2, exhibiting an IC50 of 3 nM, and is utilized in glioblastoma research [1].</p>Fórmula:C27H26FN7Cor e Forma:SolidPeso molecular:467.54113-O12B
CAS:<p>"113-O12B is an ionizable cationic lipidoid containing a disulfide bond, utilized in the generation of lipid nanoparticles (LNPs) for mRNA delivery [1]."</p>Fórmula:C57H111N3O8S8Cor e Forma:SolidPeso molecular:1223.03COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Fórmula:C17H16N6O3SPureza:98%Cor e Forma:SolidPeso molecular:384.41FASN-IN-1
CAS:<p>FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme</p>Fórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Cor e Forma:SolidPeso molecular:395.54BI-11634
CAS:<p>BI-11634 is a factor Xa inhibitor.</p>Fórmula:C22H23ClN4NaO4Pureza:98%Cor e Forma:SolidPeso molecular:465.89113-O16B
CAS:<p>113-O16B, an ionizable cationic lipidoid featuring a disulfide bond, is utilized in producing lipid nanoparticles (LNPs) for mRNA delivery [1].</p>Fórmula:C73H143N3O8S8Cor e Forma:SolidPeso molecular:1447.45FR-186054
CAS:<p>FR-186054, a potent ACAT inhibitor with high oral efficacy, outperforms others in vitro regardless of dosage.</p>Fórmula:C26H27N5OS2Pureza:98%Cor e Forma:SolidPeso molecular:489.66MT-3014
CAS:<p>MT-3014: Strong, selective brain-penetrating PDE 10A inhibitor; IC50 0.062 nM (human), 0.09 nM (bovine).</p>Fórmula:C23H25F2N7OPureza:98%Cor e Forma:SolidPeso molecular:453.49DNCA
CAS:<p>DNCA, a neutral lipid, facilitates the creation of lipid nanoparticles (LNPs) and is instrumental in [nucleic acid delivery](1).</p>Fórmula:C45H82N4O4Cor e Forma:SolidPeso molecular:743.16ICMT-IN-31
CAS:<p>ICMT-IN-31 (compound 68) serves as an ICMT inhibitor, demonstrating significant potency with an IC50 value of 0.0038 μM [1].</p>Fórmula:C19H24ClNOSCor e Forma:SolidPeso molecular:349.921-Palmitoyl-2-Oleoyl-3-Stearoyl-rac-glycerol
CAS:<p>1-Palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol, a primary triacylglycerol in cocoa butter, features palmitic acid (at the sn-1 position), oleic acid (at the sn-2 position), and stearic acid (at the sn-3 position).</p>Fórmula:C55H104O6Cor e Forma:SolidPeso molecular:861.41
