Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(177 produtos)
- Caseína quinase(130 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(267 produtos)
- FAAH(63 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(53 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(32 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(96 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(165 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8597 produtos de "Metabolismo"
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Dihomo-γ-Linolenic acid methyl ester
CAS:<p>Dihomo-γ-Linolenic acid methyl ester is the methyl ester form of Dihomo-γ-Linolenic acid which has anti-inflammatory and anti-proliferative effects.</p>Fórmula:C21H36O2Pureza:≥98%Cor e Forma:SolidPeso molecular:320.51Morin 3-O-β-D-glucopyranoside
CAS:<p>Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties.</p>Fórmula:C21H20O12Cor e Forma:SolidPeso molecular:464.38PEG2000-C-DMG
CAS:<p>PEG2000-C-DMG is a pegylated lipid for Onpattro, reducing transthyretin production via RNAi.</p>Fórmula:C126H249NO52Cor e Forma:SolidPeso molecular:2000 (Average)11(Z),14(Z)-Eicosadienoic Acid methyl ester
CAS:<p>Methyl ester of 11(Z),14(Z)-eicosadienoic acid is a ω-6 PUFA, inhibits LTB4 binding and IMP dehydrogenase, and might affect sleep.</p>Fórmula:C21H38O2Cor e Forma:SolidPeso molecular:322.53D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
CAS:<p>D-Ribofuranose 1-phosphate is used to synthesize 5-fluorouracil via uridine phosphorylase.</p>Fórmula:C11H24NO8PCor e Forma:SolidPeso molecular:329.28DSPE-PEG1000-M2pep
<p>DSPE-PEG1000-M2pep is a PEG compound comprised of DSPE and the M2 macrophage-targeting peptide (M2pep). M2pep acts as a mono- or multivalent ligand conjugated with pro-apoptotic peptides to focus the peptides' toxic effects on M2 macrophages. DSPE-PEG1000-M2pep can be utilized for drug delivery.</p>Cor e Forma:Odour Solid3α-Hydroxysteroid dehydrogenase
CAS:<p>3α-Hydroxysteroid dehydrogenase (3α-HSD), encoded by the AKR1C4 gene, is responsible for catalyzing the transformation of 3-ketosteroids into 3α-hydroxy</p>Cor e Forma:SolidPNGase F
CAS:<p>PNGase F is an endoglycosidase and amide hydrolase that catalyses the cleavage of internal glycosidic bonds in oligosaccharides.</p>Cor e Forma:SolidPrunetin 5-O-β-D-glucopyranoside
CAS:<p>Prunetin 5-O-β-D-glucopyranoside, an isoflavone obtained from Potentilla astracanica extracts, is a potent uncompetitive inhibitor of α-glucosidase (IC 50 = 56.</p>Fórmula:C22H22O10Cor e Forma:SolidPeso molecular:446.408hBChE-IN-3
<p>hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.</p>Cor e Forma:Odour Solid6-Ethyl-2,7-dimethoxyjuglone
CAS:<p>6-Ethyl-2,7-dimethoxyjuglone is a metabolite isolated from freshwater fungi [1] .</p>Fórmula:C14H14O5Cor e Forma:SolidPeso molecular:262.2621-Deoxy Cortisone
CAS:<p>21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.</p>Fórmula:C21H28O4Cor e Forma:SolidPeso molecular:344.44Abiraterone N-oxide
CAS:<p>Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>Fórmula:C24H31NO2Cor e Forma:SolidPeso molecular:365.5111β-HSD1-IN-11
CAS:<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>Fórmula:C15H11F3O3SPureza:99.61%Cor e Forma:SoildPeso molecular:328.31Burnettramic Acid A aglycone
CAS:<p>Burnettramic acid A aglycone, from A. burnettii, has anticancer properties; cytotoxic to NS-1 cells (IC50 = 8.4 μg/ml), not to fibroblasts (>100 μg/ml).</p>Fórmula:C35H61NO7Cor e Forma:SolidPeso molecular:607.873Acivicin
CAS:<p>Acivicin (AT-125) is a chlorinated amino acid antibiotic produced by Streptomyces porcineus, a GGT inhibitor with anticancer and antiparasitic activity.</p>Fórmula:C5H7ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:178.57Tacalcitol monohydrate
CAS:<p>Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.</p>Fórmula:C27H46O4Pureza:99.93%Cor e Forma:SolidPeso molecular:434.65Impurity C of Alfacalcidol
CAS:<p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Fórmula:C35H49N3O4Pureza:98%Cor e Forma:SolidPeso molecular:575.782-NP-AHD
CAS:<p>2-NP-AHD, derived from AHD/nitrofuran metabolite, indicates illegal nitrofuran use.</p>Fórmula:C10H8N4O4Cor e Forma:SolidPeso molecular:248.20β-1,3-Galactosyltransferase (CgtB)
CAS:<p>CgtB enzyme, needed for GM1-like LOS SIAL, catalyzes galactose addition in biochemical studies.</p>Cor e Forma:Solid1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
CAS:<p>Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.</p>Fórmula:C40H80NO8PPureza:99.23%Cor e Forma:SolidPeso molecular:734.04WVSAV
<p>WVSAV is a ligand for the PDZ2 domain (tyrosine phosphatase) with a dissociation constant (Kd) of 111 μM. It is utilized in studies of protein-ligand interactions.</p>Fórmula:C27H40N6O7Cor e Forma:SolidPeso molecular:560.64Cholesteryl arachidonate
CAS:<p>Cholesteryl arachidonate is a human endogenous metabolite.</p>Fórmula:C47H76O2Pureza:98%Cor e Forma:SolidPeso molecular:673.11DBPR-110
CAS:<p>DBPR-110: NS5A inhibitor, EC50 of 3.9 pM for HCV1b, SI >12.8 million; EC50 of 228.8 pM for HCV2a, SI >173,130.</p>Fórmula:C50H48N6O4S2Pureza:98%Cor e Forma:SolidPeso molecular:861.09Bifenazate-diazene
CAS:<p>Bifenazate-diazene, a significant degradation product of Bifenazate, is characterized as a selective carbazate acaricide and insecticide [1].</p>Fórmula:C17H18N2O3Cor e Forma:SolidPeso molecular:298.34Glutamic acid protease
CAS:<p>Glutamic protease, a proteolytic enzyme characterized by the presence of a glutamic acid residue [1], is exclusive to fungi.</p>Cor e Forma:SolidBiotin-Vitamin B12
<p>Biotin-Vitamin B12, a biotinylated form, is crucial for brain, nervous system function, and blood formation.</p>Fórmula:C73H102CoN16O16PSCor e Forma:SolidPeso molecular:1581.66trans-2-Hexadecenoyl-L-carnitine
CAS:<p>trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1].</p>Fórmula:C23H43NO4Cor e Forma:SolidPeso molecular:397.59N-Stearoylsphingomyelin
CAS:<p>N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin), a sphingolipid, inhibits Phospholipase Cδ1 (PLCδ1) [1].</p>Fórmula:C41H83N2O6PCor e Forma:SolidPeso molecular:731.081-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
CAS:<p>1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides .</p>Fórmula:C24H45NO7Cor e Forma:SolidPeso molecular:459.624LYS006 hydrochloride
CAS:<p>LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 value of 2 nM. It is applicable in the study of inflammatory and autoimmune diseases. For further details, please refer to compound 29 in patent document WO2015092740A1.</p>Fórmula:C16H15Cl2FN6O3Cor e Forma:SolidPeso molecular:429.23S-Phenylmercapturic acid
CAS:<p>S-Phenylmercapturic acid is a metabolite of benzene that can be used as a biomarker to assess benzene exposure.</p>Fórmula:C11H13NO3SPureza:99.68%Cor e Forma:SolidPeso molecular:239.29Fmoc-Tyr(3-F,tBu)-OH
CAS:<p>Fmoc-Tyr(3-F,tBu)-OH: Cyclic peptide with high permeability, target-specific affinity. Sourced from WO2018225864A1.</p>Fórmula:C28H28FNO5Cor e Forma:SolidPeso molecular:477.532Mono(5-carboxy-2-ethylpentyl) phthalate
CAS:<p>MECPP is a metabolite of DEHP, a major plasticizer used in flexible PVC.</p>Fórmula:C16H20O6Cor e Forma:SolidPeso molecular:308.33Impurity of Doxercalciferol
CAS:<p>Doxercalciferol impurity, synthetic ergocalciferol analog, treats secondary hyperparathyroidism, inhibits parathyroid.</p>Fórmula:C28H44O2Pureza:98%Cor e Forma:SolidPeso molecular:412.65N-Nonyldeoxynojirimycin
CAS:<p>N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively).</p>Fórmula:C15H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:289.41Pyridindolol
CAS:<p>Pyrindolol, a S. alboverticillatus metabolite, inhibits bovine β-galactosidase at 2 μg/ml in acid; not effective on other species' enzymes.</p>Fórmula:C14H14N2O3Cor e Forma:SolidPeso molecular:258.2773'-sulfo Galactosylsphingosine (ammonium salt)
CAS:<p>Sulfatide derivative inhibits cell migration, adhesion, PKC, cytochrome c; accumulates in metachromatic leukodystrophy; used for LC-MS quantification.</p>Fórmula:C24H50N2O10SCor e Forma:SolidPeso molecular:558.73Terpendole C
CAS:<p>Terpendole C, an indole diterpene from A. yamanashiensis, inhibits ACAT with IC50 of 2.1 μM in rats, 0.46 μM in J774 cells, non-toxic.</p>Fórmula:C32H41NO5Cor e Forma:SolidPeso molecular:519.682Ilexoside XLVIII
CAS:<p>Ilexoside XLVIII, a triterpene saponin from Ilex kudincha leaves, inhibits ACAT.</p>Fórmula:C42H66O15Cor e Forma:SolidPeso molecular:810.96Carboxylesterase
CAS:<p>CESs are enzymes in mammalian liver hydrolyzing esters and other substrates in biochemical studies.</p>Cor e Forma:SolidStephacidin B
CAS:<p>Stephacidin B, from A. ochraceus, forms avrainvillamide in vitro. Cytotoxic to various cancer cells; induces apoptosis in hepatocarcinoma at 4 μM.</p>Fórmula:C52H54N6O8Cor e Forma:SolidPeso molecular:891.038GW590735
CAS:<p>GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.</p>Fórmula:C23H21F3N2O4SPureza:99.53%Cor e Forma:SolidPeso molecular:478.48Ionizable Lipid 4
CAS:<p>Ionizable Lipid 4 is an ionizable cationic lipid that forms as a product of the rearrangement of cationic lipid CA-lipid 5 under hydrogen peroxide induction.</p>Fórmula:C48H85NO7Cor e Forma:SolidPeso molecular:788.19TNAP-IN-1
CAS:<p>TNAP-IN-1 is a specific inhibitor of tissue-nonspecific alkaline phosphatase (TNAP) and is utilized in studying diseases related to soft tissue calcification.</p>Fórmula:C17H16N2O4SPureza:99.03%Cor e Forma:SolidPeso molecular:344.39Sarcinapterin
CAS:<p>Sarcinapterin is a coenzyme isolated from Methanosarcina barkeri.</p>Fórmula:C35H48N7O19PCor e Forma:SolidPeso molecular:901.773BE2647
<p>BE2647 is a selective inhibitor of the mitochondrial pyruvate carrier (MPC), with an EC50 of 70 nM. It exhibits good metabolic stability in mouse liver microsomes. BE2647 can be utilized in research related to metabolic diseases, metabolic-associated steatotic liver disease (MASLD), or metabolic-associated steatohepatitis (MASH).</p>Fórmula:C13H7Br2N3O2Cor e Forma:SolidPeso molecular:397.022Pyrocatechol
CAS:<p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>Fórmula:C6H6O2Cor e Forma:SolidPeso molecular:110.11DSPE-PEG-Maleimide (MW 3400) ammonium
<p>DSPE-PEG-Maleimide (MW 3400) ammonium combines DSPE phospholipids with maleimide for the preparation of nanostructured lipid carriers. It is applicable in drug delivery research.</p>Cor e Forma:Odour SolidPropionylcarnitine
CAS:<p>Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptu</p>Fórmula:C10H19NO4Pureza:99.69%Cor e Forma:SolidPeso molecular:217.26MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Fórmula:C21H15N3O4Cor e Forma:SolidPeso molecular:373.36Ganglioside sialidase (AuSialidase S)
CAS:<p>AuSialidase S is an endogenous metabolite involved in neuronal differentiation and neurite outgrowth.</p>Cor e Forma:SolidFerulic acid acyl-β-D-glucoside
CAS:<p>Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1).</p>Fórmula:C16H20O9Cor e Forma:SolidPeso molecular:356.327Adenosylhomocysteinase
CAS:<p>SAHH, an enzyme, reversibly converts SAH into adenosine and L-homocysteine, and may predict HBV-LC outcomes.</p>Fórmula:C14H13N3O2S2Cor e Forma:SolidPeso molecular:319.04492DSPE-PEG5000-VIP
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. DSPE-PEG2000-TAT is applicable for drug delivery.</p>Cor e Forma:Odour Solid(-)-Jasmonoyl-L-isoleucine
CAS:<p>(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile), an enantiomer of (+)-JA-L-Ile [1], is an inactive endogenous hormone.</p>Fórmula:C18H29NO4Cor e Forma:SolidPeso molecular:323.434-hydroxy Hexenal
CAS:<p>4-Hydroxy hexenal (4-HHE) are toxic aldehydes that are enriched in flavored gravies and cooking oils with storage time and elevated temperatures.</p>Fórmula:C6H10O2Cor e Forma:SolidPeso molecular:114.14MK-8245 Trifluoroacetate
CAS:<p>MK-8245 trifluoroacetate: Potent liver-targeting SCD inhibitor, IC50=1nM (human). Anti-diabetic/anti-dyslipidemic. Selective, with low adverse event exposure.</p>Fórmula:C19H17BrF4N6O6Cor e Forma:SolidPeso molecular:581.27(±)13(14)-DiHDPA
CAS:<p>(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.</p>Fórmula:C22H34O4Cor e Forma:SolidPeso molecular:362.51Formate dehydrogenase
CAS:<p>Formate dehydrogenase, found in all life forms, converts formate to CO2 and is categorized by metal content for research.</p>Cor e Forma:SolidMP 518
CAS:<p>MP 518 is a PDE inhibitor with antihypertensive properties. It prevents the degradation of cAMP, leading to increased ICa levels, and counteracts the effects of β-adrenergic stimulation, resulting in vasodilation.</p>Fórmula:C10H11ClN2O2Cor e Forma:SolidPeso molecular:226.66DSPE-PEG1000-T7
<p>DSPE-PEG1000-T7 is a PEG compound composed of DSPE and transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR. DSPE-PEG1000-T7 is applicable in drug delivery.</p>Cor e Forma:Odour SolidCholesteryl Homo-γ-Linolenate
CAS:<p>Cholesteryl homo-γ-linolenate is a cholesterol ester.</p>Fórmula:C47H78O2Cor e Forma:SolidPeso molecular:675.139Remdesivir de(ethylbutyl 2-aminopropanoate)
CAS:<p>Remdesivir impurity with antiviral activity; EC50: SARS-CoV/MERS-CoV 74 nM, murine hepatitis virus 30 nM. Effective against COVID-19 in vitro.</p>Fórmula:C18H18N5O7PCor e Forma:SolidPeso molecular:447.34HIF1-IN-3
CAS:<p>HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in</p>Fórmula:C26H24N2O3Pureza:99.59%Cor e Forma:SolidPeso molecular:412.48Dihydrozeatin riboside
CAS:<p>Dihydrozeatin riboside is a cytokinin that can be isolated from Phaseolus vulgaris L.</p>Fórmula:C15H23N5O5Cor e Forma:SolidPeso molecular:353.37Glycodeoxycholic acid monohydrate
CAS:<p>Glycodeoxycholic acid monohydrate is a nuclear receptor ligand.</p>Fórmula:C26H45NO6Cor e Forma:SolidPeso molecular:467.64Reduced Haloperidol
CAS:<p>Reduced haloperidol, an active metabolite of haloperidol, binds dopamine D2/sigma-1 receptors and inhibits neurotransmitter reuptake.</p>Fórmula:C21H25ClFNO2Cor e Forma:SolidPeso molecular:377.88Carbazeran citrate
CAS:<p>aldehyde oxidase (AO) substrate</p>Fórmula:C24H32N4O11Pureza:98%Cor e Forma:SolidPeso molecular:552.5328-Epirapamycin
CAS:<p>28-Epirapamycin, an impurity of Rapamycin, serves as a potent and specific mTOR inhibitor, exhibiting an IC50 value of 0.1 nM in HEK293 cells [1].</p>Fórmula:C51H79NO13Cor e Forma:SolidPeso molecular:914.17CM121
CAS:<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Fórmula:C24H17FN4O3SCor e Forma:SolidPeso molecular:460.48LH1513
<p>LH1513 is a dioxalate salt derivative of l-lysine that inhibits CaOx crystallization more effectively than citrate and pyruvate. It shows potential preventive activity in hyperoxaluria models and effectively prevents urinary CaOx crystal formation in Agxt knockout mice. AGXT-1 is a mitochondrial protein involved in metabolic processes.</p>Fórmula:C10H11N2Na3O8Cor e Forma:SolidPeso molecular:356.17Asperlactone
CAS:<p>Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.</p>Fórmula:C9H12O4Cor e Forma:SolidPeso molecular:184.191(3S,5R)-Fluvastatin D6 sodium
CAS:<p>(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.</p>Fórmula:C24H25FNNaO4Pureza:98%Cor e Forma:SolidPeso molecular:439.49(±)-Equol 4'-sulfate (sodium salt)
CAS:<p>(±)-Equol 4’-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol .[1] It has been used as a standard for the</p>Fórmula:C15H13NaO6SCor e Forma:SolidPeso molecular:344.32DSPE-PEG2000-NYZL1
<p>DSPE-PEG2000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 is suitable for drug delivery applications.</p>Cor e Forma:Odour SolidACAT-IN-4
CAS:<p>ACAT-IN-4 inhibits ACAT and NF-κB-mediated transcription.</p>Fórmula:C32H50N2O5SCor e Forma:SolidPeso molecular:574.8213,14-dehydro-15-cyclohexyl Carbaprostacyclin
CAS:<p>13,14-dehydro-15-cyclohexyl Carbaprostacyclin, a stable PGI2 analog, impedes ADP-induced platelet aggregation; ED50 ~40 nM in PRP, 77 nM in washed platelets.</p>Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.467H-Ile-Pro-Pro-OH
CAS:<p>H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM.</p>Fórmula:C16H27N3O4Pureza:98%Cor e Forma:SolidPeso molecular:325.4CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Fórmula:C23H21N5O3SCor e Forma:SolidPeso molecular:447.51Glycidamide
CAS:<p>Glycidamide is a carcinogen and metabolite of acrylamide that induces DNA adduct formation and mutations.</p>Fórmula:C3H5NO2Cor e Forma:SolidPeso molecular:87.08Rostratin C
CAS:<p>Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.</p>Fórmula:C20H24N2O8S2Cor e Forma:SolidPeso molecular:484.54DSPE-PEG2000-Azide ammonium
CAS:<p>DSPE-PEG2000-Azide ammonium is a lipid-based azide compound used in forming micelles for nanoparticle drug delivery. It serves as a click chemistry reagent and includes an azide group that reacts with molecules containing an alkyne group through a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc). Additionally, it can engage in a strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.</p>Cor e Forma:SolidN-Acetylhexosamine kinase (NahK)
CAS:<p>NahK phosphorylates GlcNAc/GalNAc at C1 using ATP to form GlcNAc-1P/GalNAc-1P.</p>Cor e Forma:SolidDorzolamide
CAS:<p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>Fórmula:C10H16N2O4S3Pureza:98%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:324.44N-Pivaloyl-L-tyrosine
CAS:<p>N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester.</p>Fórmula:C14H19NO4Cor e Forma:SolidPeso molecular:265.30Aldose 1-epimerase
CAS:<p>Aldose 1-epimerase facilitates the conversion of α- to β-sugars like glucose, crucial for carbohydrate processing.</p>Cor e Forma:SolidOphiobolin A
CAS:<p>Ophiobolin A: Fungal metabolite, phytotoxin, inhibits calmodulin-activated phosphodiesterase (IC50: 9μM), with antimicrobial and anticancer properties.</p>Fórmula:C25H36O4Pureza:98%Cor e Forma:SolidPeso molecular:400.559α,α-Trehalose 6-phosphate potassium
CAS:<p>α,α-Trehalose 6-phosphate (Tre6P) potassium is an intrinsic 6-phosphate derivative of α,α′-trehalose and acts as an intermediary metabolite.</p>Fórmula:C12H21K2O14PPureza:98%Cor e Forma:SolidPeso molecular:498.46Roridin L2
CAS:<p>Roridin L2 is a natural product for research related to life sciences. The catalog number is T41264 and the CAS number is 85124-22-7.</p>Fórmula:C29H38O9Cor e Forma:SolidPeso molecular:530.614Febuxostat impurity 7
CAS:<p>Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H18N2O4SCor e Forma:SolidPeso molecular:334.39C17 Sphingomyelin (d18:1/17:0)
CAS:<p>C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.</p>Fórmula:C40H81N2O6PCor e Forma:SolidPeso molecular:717.05Lipstatin
CAS:<p>Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.</p>Fórmula:C29H49NO5Pureza:98%Cor e Forma:SolidPeso molecular:491.7Dilaurylglycerosulfate
CAS:<p>Dilauryl glycerol sulfate is an auxiliary emulsifier for lipase determination.</p>Fórmula:C27H56O6SPureza:98%Cor e Forma:SolidPeso molecular:508.8Octachlorodibenzo-p-dioxin
CAS:<p>Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant with no acute toxicity when administered. In rats, the systemic elimination half-life of Octachlorodibenzo-p-dioxin (50 μg/kg intravenously or 50-5000 μg/kg orally) is 3-5 months. It can accumulate and concentrate in the liver and adipose tissue after low-dose, repeated exposure. Repeated dosing of Octachlorodibenzo-p-dioxin leads to increased activity of 7-ethoxyresorufin-O-deethylase (7-EROD) and elevated total cytochrome P-450 levels.</p>Fórmula:C12Cl8O2Cor e Forma:SolidPeso molecular:459.75EC1454
CAS:<p>EC1454 is an anti-tumor compound.</p>Fórmula:C65H98N16O34SPureza:98%Cor e Forma:SolidPeso molecular:1679.63Acrihellin
CAS:<p>Acrihellin is a cardioactive steroid, a cardiotonic drug.</p>Fórmula:C29H38O7Cor e Forma:SolidPeso molecular:498.61DSPE-PEG2000-CSTSMLKAC
<p>DSPE-PEG2000-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. CSTSMLKAC can mediate phage selective homing to ischemic heart tissue. DSPE-PEG2000-CSTSMLKAC is suitable for drug delivery.</p>Cor e Forma:Odour SolidMavodelpar free acid hydrochloride
<p>Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.</p>Fórmula:C31H31ClFNO5Pureza:98.13%Cor e Forma:SoildPeso molecular:552.03Nε,Nε,Nε-Trimethyllysine chloride
CAS:<p>Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine and a component of histone proteins.</p>Fórmula:C9H21ClN2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:224.73Sialyl-Lewis X
CAS:<p>sLeX: sialylated, fucosylated tetrasaccharide, ligand for selectins, inhibits neutrophil recruitment.</p>Fórmula:C31H52N2O23Cor e Forma:SolidPeso molecular:820.748α-Glucosidase-IN-60
<p>α-Glucosidase-IN-60 (Compound 5k) acts as a competitive inhibitor of α-Glucosidase, with an IC50 of 10.8 μM.</p>Fórmula:C23H14N2O5Peso molecular:398.09027Febuxostat impurity 6
CAS:<p>Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C18H22N2O4SCor e Forma:SolidPeso molecular:362.44DOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Fórmula:C61H88N16O22S2Cor e Forma:SolidPeso molecular:1461.57Galactose 1-dehydrogenase
<p>Galactose 1-dehydrogenase, pseudomonas fluorescens, a dehydrogenase found in Pseudomonas fluorescens, facilitates the oxidation of L-arabinose and D-galactose, utilizing NADP+/NAD+ as a cofactor. This enzyme is employed in diagnostic assays to quantify total galactose levels and serves as a biocatalyst in the production of galacturonic acid salts.</p>Cor e Forma:Odour Solidα-Glucosidase-IN-27
<p>α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1</p>Fórmula:C22H20N4O4SPureza:98%Cor e Forma:SolidPeso molecular:436.48ω-Conotoxin Bu8
<p>ω-Conotoxin Bu8 is a 25-amino-acid-residue ω-conotoxin that features three disulfide bridges.</p>Fórmula:C103H174N42O35S6Pureza:98%Cor e Forma:SolidPeso molecular:2753.13GSK-3β/CK-1δ-IN-1
<p>GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.</p>Fórmula:C22H17F3N4OCor e Forma:SolidPeso molecular:410.39α-1,4-Galactosyltransferase (LgtC)
CAS:<p>A4GALT (LgtC) adds galactose to lactosylceramide, forming globotriaosylceramide; used in P1 antigen synthesis.</p>Cor e Forma:SolidNPE-caged-proton
CAS:<p>Generates rapid acidifications down to pH 2</p>Fórmula:C8H9NNaO6SPureza:98%Cor e Forma:SolidPeso molecular:270.22Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Fórmula:C6H8N2O2SCor e Forma:SolidPeso molecular:172.2DSPE-PEG1000-ANG
<p>DSPE-PEG1000-ANG is a PEG compound composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG demonstrates high LRP1 binding efficiency and has been utilized for targeting glioma delivery. DSPE-PEG1000-ANG is suitable for drug delivery applications.</p>Cor e Forma:Odour SolidFumonisin B2
CAS:<p>Fumonisin B2, from Fusarium moniliforme in grains, blocks ceramide synthase, disrupting sphingolipid biosynthesis.</p>Fórmula:C34H59NO14Pureza:98%Cor e Forma:SolidPeso molecular:705.83C18:1 Ceramide (d18:1/18:1(9Z))
CAS:<p>C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant , advanced ovarian cancer.</p>Fórmula:C36H69NO3Pureza:99.96%Cor e Forma:SolidPeso molecular:563.94SAICAR
CAS:<p>SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).</p>Fórmula:C13H19N4O12PPureza:98%Cor e Forma:SolidPeso molecular:454.28DSPE-PEG1000-octreotide
<p>DSPE-PEG1000-Octreotide, a PEG compound formed from DSPE and Octreotide, acts as a somatostatin receptor agonist. Octreotide exhibits antitumor properties and induces apoptosis, making it useful in researching acromegaly. Additionally, DSPE-PEG1000-Octreotide is applicable in drug delivery.</p>Cor e Forma:Odour SolidENPP3 Inhibitor 1
CAS:<p>ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, exhibiting an IC50 value of 0.15 µM, compared to an IC50 of 41.4 µM for ENPP1. It demonstrates antitumor effects against breast and cervical cancers.</p>Fórmula:C20H14F3NO5SCor e Forma:SolidPeso molecular:437.39Revizinone
CAS:<p>Revizinone is a novel selective phosphodiesterase inhibitor with IC50 values on this enzyme to 0.036 microM.</p>Fórmula:C26H29N5O3Pureza:98%Cor e Forma:SolidPeso molecular:459.54Tpp-CAQK
<p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>Fórmula:C40H54BrN6O7PSCor e Forma:SolidPeso molecular:873.843α-Hydroxy pravastatin sodium
CAS:<p>3α-Hydroxy pravastatin sodium, the primary metabolite of Pravastatin, is a potent competitive inhibitor of HMG-CoA reductase.</p>Fórmula:C23H36NaO7Cor e Forma:SolidPeso molecular:447.524Cryptosporioptide A
CAS:<p>Cryptosporioptide A (Compound 3), a protein tyrosine phosphatase inhibitor, originates from the insect-parasitic fungus Cordyceps gracilioides.</p>Fórmula:C18H17NO10Pureza:98%Cor e Forma:SolidPeso molecular:407.33Beauverolide Ja
CAS:<p>Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.</p>Fórmula:C35H46N4O5Cor e Forma:SolidPeso molecular:602.76DJ-53
<p>DJ-53 (compound 68) is an orally active, phenyl-quinoline-based soluble epoxide hydrolase inhibitor.</p>Cor e Forma:Odour SolidTetrahydropteroylpentaglutamate
CAS:<p>H4PteGlu5 strongly inhibits itself and tightly binds in vivo, almost irreversibly, as a coenzyme.</p>Fórmula:C39H51N11O18Pureza:98%Cor e Forma:SolidPeso molecular:961.895α-Hydroxy-6-keto cholesterol
CAS:<p>Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.</p>Fórmula:C27H46O3Cor e Forma:SolidPeso molecular:418.662Monoisobutyl phthalic acid
CAS:<p>Monoisobutyl phthalic acid is a metabolite of phthalate that is in human semen and in meconium.</p>Fórmula:C12H14O4Pureza:98%Cor e Forma:SolidPeso molecular:222.24hCAXII-IN-7
<p>hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.</p>Fórmula:C26H25N5O6S2Pureza:98%Cor e Forma:SolidPeso molecular:567.64FXR agonist 10
<p>FXR agonist10 (Compound 27) acts as an agonist for FXR with an EC50 of 14.26 μM. It increases the expression of SHP and BSEP proteins while decreasing the expression of NTCP and CYP7A1 proteins. Additionally, FXR agonist10 has been shown to ameliorate ANIT-induced cholestasis in mouse models.</p>Fórmula:C15H22O4Cor e Forma:SolidPeso molecular:266.33GS-704277
CAS:<p>GS-704277, a Remdesivir metabolite, shows potent in vitro effects against COVID-19.</p>Fórmula:C15H19N6O8PCor e Forma:SolidPeso molecular:442.325α-Amylase/α-Glucosidase-IN-17
<p>α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.</p>Fórmula:C19H18FNOCor e Forma:SolidPeso molecular:295.35RSRGVFF
<p>RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with the ability to penetrate the blood-brain barrier, exhibiting an IC50 value of 5.01 μM. It binds to both active and inactive sites of ACE and its substrate HHL complex, thereby reducing the catalytic activity of ACE. RSRGVFF can be further explored for hypertension research.</p>Fórmula:C40H61N13O9Cor e Forma:SolidPeso molecular:867.994α-Muricholic acid
CAS:<p>α-Muricholic acid is the most abundant primary bile acid in rodents.</p>Fórmula:C24H40O5Pureza:98%Cor e Forma:SolidPeso molecular:408.57Spaglumic acid acetate
<p>Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.</p>Fórmula:C13H20N2O10Pureza:99.49%Cor e Forma:SolidPeso molecular:364.31Kahalalide A
CAS:<p>Kahalalide A has antimycobacterial activity isolated from the mollusk Elysia rufescens.</p>Fórmula:C46H67N7O11Pureza:98%Cor e Forma:SolidPeso molecular:894.082′,3′-Di-O-acetyl-5′-deoxy-5-fluorocytidine
CAS:<p>2'',3''-Di-O-acetyl-5''-deoxy-5-fuluro-D-cytidine is a derivative of capecitabine.</p>Fórmula:C13H16FN3O6Pureza:99.51%Cor e Forma:SolidPeso molecular:329.285A2-SC8 TFA
<p>5A2-SC8 TFA is an ionizable amino lipid used in lipid nanoparticles (LNPs), offering high delivery potential and low in vivo toxicity. It effectively delivers small RNAs, such as siRNA and miRNA, to tumor cells. Moreover, 5A2-SC8 TFA LNPs provide unique delivery paths for RNA within the liver, enhancing therapeutic outcomes in cancer models.</p>Cor e Forma:Odour SolidAHK
CAS:<p>AHK, a bioactive peptide known for its antioxidant properties, has been employed as a cosmetic ingredient [1].</p>Fórmula:C15H26N6O4Pureza:98%Cor e Forma:SolidPeso molecular:354.418-Hydroxycorticosterone
CAS:<p>18-Hydroxycorticosterone is a corticosteroid and corticosterone derivative, which can lead to serious electrolyte imbalances.</p>Fórmula:C21H30O5Pureza:98%Cor e Forma:SolidPeso molecular:362.46PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Fórmula:C23H28FN7O3Cor e Forma:SolidPeso molecular:469.51Citrulline malate
CAS:<p>Citrulline malate is a cpd of anti-fatigue.</p>Fórmula:C10H19N3O8Pureza:98%Cor e Forma:SolidPeso molecular:309.27AZD-3199 free base
CAS:<p>AZD-3199, a β2 adrenergic receptor agonist, is used potentially for the treatment of asthma and chronic obstructive.</p>Fórmula:C32H42N4O4SCor e Forma:SolidPeso molecular:578.77UK140
<p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>Fórmula:C72H105N19O25S3Cor e Forma:SolidPeso molecular:1732.91BMS 195614
CAS:<p>BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.</p>Fórmula:C29H24N2O3Pureza:97.7%Cor e Forma:SolidPeso molecular:448.51hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Cor e Forma:Odour SolidMortatarin G
<p>Mortatarin G (compound 3), a prenylated flavonoid derived from mulberry leaves, demonstrates potent α-glucosidase inhibition, evidenced by an IC50 value of 20.4</p>Fórmula:C25H28O6Pureza:98%Cor e Forma:SolidPeso molecular:424.49IDO1-IN-11
CAS:<p>IDO1-IN-11 is an IDO1 inhibitor with an IC 50 value of 0.6 nM.</p>Fórmula:C22H17ClFN3O3Cor e Forma:SolidPeso molecular:425.842,3-Indolobetulonic Acid
CAS:<p>2,3-Indolobetulonic acid is pentacyclic triterpenoid derivative of betulonic acid and an inhibitor of α-glucosidase (IC50= 1.8 μM).1</p>Fórmula:C36H49NO2Cor e Forma:SolidPeso molecular:527.793(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
CAS:<p>(S,R,S)-AHPC-C2-amide targets Smad3 degradation and boosts HIF-α; it has anti-fibrotic and renal protective roles.</p>Fórmula:C41H46N6O6SCor e Forma:SolidPeso molecular:750.91Leucomyosuppressin
CAS:<p>Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.</p>Fórmula:C59H84N16O15Pureza:98%Cor e Forma:SolidPeso molecular:1257.418Ppack trifluoroacetate
CAS:<p>Ppack trifluoroacetate: Peptide, inhibits thrombin, prevents clotting (Ki: 0.24 nM), used in anticoagulation & thrombin research.</p>Fórmula:C23H32ClF3N6O5Pureza:98%Cor e Forma:SolidPeso molecular:564.99N4-Acetylcytidine triphosphate
CAS:<p>N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .</p>Fórmula:C11H18N3O15P3Pureza:98%Cor e Forma:SolidPeso molecular:525.19Pyrrophenone
CAS:<p>Pyrrophenone selectively and reversibly inhibits cPLA2 (IC50=4.2 nM), blocks AA, PGE2, and LTC4 production in cells, and is less effective on other PLA2s.</p>Fórmula:C49H37F2N3O5S2Cor e Forma:SolidPeso molecular:849.97DSPE-PEG2000-TAASGVRSMH
<p>DSPE-PEG2000-TAASGVRSMH is a PEG compound composed of DSPE and TAASGVRSMH. This compound exhibits strong affinity for the NG2 proteoglycan on PC membranes. DSPE-PEG2000-TAASGVRSMH can be utilized for drug delivery.</p>Cor e Forma:Odour SolidArchangelicin
CAS:<p>Archangelicin is a useful organic compound for research related to life sciences. The catalog number is T125179 and the CAS number is 2607-56-9.</p>Fórmula:C24H26O7Cor e Forma:SolidPeso molecular:426.465NCGC00092410
CAS:<p>NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM.</p>Fórmula:C21H27N3O2Pureza:98.68%Cor e Forma:SolidPeso molecular:353.46NF-κB/HIF-1α-IN-1
<p>NF-κB/HIF-1α-IN-1 (compound 9c) effectively inhibits the NF-κB activation pathway and demonstrates selective antifibrotic activity. This compound exhibits no significant cytotoxicity in NCI tumor cell lines. In rat models, NF-κB/HIF-1α-IN-1 successfully ameliorates liver fibrosis, suppresses the expression levels of NF-κB and HIF-1α, and induces Nrf2.</p>Fórmula:C24H27N7O4Cor e Forma:SolidPeso molecular:477.21245ZINC77292789
CAS:<p>ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which</p>Fórmula:C33H38N2O13Pureza:99.24%Cor e Forma:SolidPeso molecular:670.66Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Fórmula:C15H14F3N3O4S2Pureza:98% - >99.99%Cor e Forma:Crystals From Dioxane SolidPeso molecular:421.414-Phytase
CAS:<p>4-Phytase is a phosphohydrolase of inositol hexaphosphate [1] .</p>Cor e Forma:SolidACAT-IN-7
CAS:<p>ACAT-IN-7 inhibits ACAT enzyme; blocks NF-κB mediated transcription.</p>Fórmula:C32H49N3O5SCor e Forma:SolidPeso molecular:587.8211β-HSD1 inibitor 19
CAS:<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Fórmula:C19H16ClF4N3O2SPureza:99.58%Cor e Forma:SoildPeso molecular:461.86Alitame hydrate
CAS:<p>Alitame hydrate is a non-nutritive sweetener that is 2000 times sweeter than sucrose. It is formed from aspartic acid, alanine &amp; an amide.</p>Fórmula:C14H25N3O4SH2OCor e Forma:SolidPeso molecular:376.47trans-5-Hydroxyferulic acid
CAS:<p>trans-5-Hydroxyferulic acid is a useful organic compound for research related to life sciences. The catalog number is T126397 and the CAS number is 110642-42-7.</p>Fórmula:C10H10O5Cor e Forma:SolidPeso molecular:210.185Mefox
CAS:<p>Mefox is a bioactive chemical.</p>Fórmula:C20H23N7O7Cor e Forma:SolidPeso molecular:473.44Tauro-α-muricholic Acid (sodium salt)
CAS:<p>Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary</p>Fórmula:C26H44NNaO7SCor e Forma:SolidPeso molecular:537.69Glucuronokinase (AtGlcAK)
CAS:<p>AtGlcAK: GHMP-kinase family, specific for D-glucuronic acid, Km 0.7 mM, converts it with ATP to D-glucuronic-1-phosphate and ADP.</p>Cor e Forma:Solidm-Tyramine
CAS:<p>m-Tyramine has effects on the adrenergic and dopaminergic receptor.m-Tyramine is an endogenous trace amine neuromodulator.</p>Fórmula:C8H11NOPureza:98%Cor e Forma:SolidPeso molecular:137.18Sphingolipid ceramide N-deacylase (SCDase)
CAS:<p>SCDase splits fatty acids from sphingosine in glycosphingolipids, forming lysoglycosphingolipids.</p>Cor e Forma:Solidm-PEG8-DSPE
<p>m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>Fórmula:C59H116NO17PPureza:98%Cor e Forma:SolidPeso molecular:1142.5213-cis-Retinyl acetate
CAS:<p>13-cis-Retinyl acetate: active 13-cis isomer of Retinyl acetate, metabolite of vitamin A.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49CYP51-IN-17
<p>CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. It exhibits significant fungicidal activity against B. cinerea, with an EC50 of 0.326 μg/mL.</p>Fórmula:C24H20N2O7Peso molecular:448.12705PTP1B-IN-25
<p>PTP1B-IN-25 (Compound 19) is an inhibitor of PTP1B with notable antiviral, antibacterial, and antidiabetic activities. It exhibits IC50 values of 0.37 μM for PTP1B, 8.6 μM for HIV, 3.7 μM for α-Glucosidase, and 29 μM for methicillin-resistant Staphylococcus aureus (MRSA).</p>Fórmula:C44H66O17Peso molecular:866.43Human Factor VIIa
<p>HumanFactor VIIa is a vitamin K-dependent serine protease involved in the blood coagulation process. It has the ability to activate coagulation factor X, which in turn converts prothrombin into thrombin, leading to the transformation of fibrinogen into fibrin and resulting in the formation of blood clots. HumanFactor VIIa holds potential for improving hemophilia.</p>Kazusamycin A
CAS:<p>Kazusamycin A is a new antitumor antibiotic.</p>Fórmula:C33H48O7Cor e Forma:SolidPeso molecular:556.74Imidazole-d4
CAS:<p>Imidazole-d4 is an isotope-labeled variant of imidazole, which is a heterocyclic aromatic compound. Imidazole molecules serve as inhibitors for acetylcholinesterase (AChEI) and xanthine oxidase (XO) and have been utilized as corrosion inhibitors. They display a range of biological activities, including antifungal, antitubercular, anti-inflammatory, antioxidant, and analgesic properties. Imidazole inhibits platelet microsomes from converting endoperoxides (PGG2 and PGH2) into thromboxane A2. Additionally, imidazole derivatives show inhibitory effects on the SARS-CoV-2 3CLpro enzyme, offering potential for research in Alzheimer’s disease, gout, COVID-19, and thrombotic disorders.</p>Fórmula:C3H4N2Cor e Forma:SolidPeso molecular:72.1Abiraterone sulfate
CAS:<p>Abiraterone sulfate is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>Fórmula:C24H31NO4SCor e Forma:SolidPeso molecular:429.57ST6 Sialyltransferase 5
<p>ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.</p>11-trans Leukotriene C4
CAS:<p>11-trans LTC4 is a C-11 isomer of LTC4, forms slowly on storage, is less common but similarly potent in contractions, pKis: 6.42 (LTC4), 6.58 (11-trans).</p>Fórmula:C30H47N3O9SCor e Forma:SolidPeso molecular:625.78PF-1355
CAS:<p>PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.</p>Fórmula:C14H15N3O4SPureza:99.93%Cor e Forma:SolidPeso molecular:321.35Antibacterial agent 218
<p>Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.</p>Fórmula:C30H24N4OSPeso molecular:488.16708α-Glucosidase-IN-49
<p>α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with an IC50 of 0.52 μM. This compound exhibits oral bioactivity, effectively lowering blood glucose levels and enhancing glucose tolerance in mice.</p>Fórmula:C21H13F3N4O3S3Peso molecular:522.01019IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Cor e Forma:SoildPeso molecular:367.36Calcium 2-oxoglutarate
CAS:<p>Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).</p>Fórmula:C5H8CaO5Pureza:98%Cor e Forma:SolidPeso molecular:188.192Abieslactone
CAS:<p>Abieslacton possesses anti-tumor promoting activity isolated from several Abies genus.</p>Fórmula:C31H48O3Cor e Forma:SolidPeso molecular:468.72210-Formyldihydrofolate
CAS:<p>10-Formyldihydrofolate is a Methotrexate metabolite. It inhibits thymidylate synthetase and glycinamide ribotide transformylase.</p>Fórmula:C20H21N7O7Cor e Forma:SolidPeso molecular:471.43Ftase inhibitor III
CAS:<p>Ftase Inhibitor III, derived from a phenotypic screen, functions as an anion-dependent inhibitor of Farnesyltransferase.</p>Fórmula:C24H34N6OCor e Forma:SolidPeso molecular:422.577L-Mevalonic acid
CAS:<p>L-Mevalonic acid, a cholesterol precursor, is studied in autoimmune, atherosclerosis, and Alzheimer's research.</p>Fórmula:C6H12O4Pureza:98%Cor e Forma:SolidPeso molecular:148.16O-Demethyl Lenvatinib hydrochloride
<p>O-Demethyl Lenvatinib HCl is a Lenvatinib metabolite; an oral inhibitor targeting VEGFR, FGFR, PDGFR, KIT, RET with antitumor properties.</p>Fórmula:C20H18Cl2N4O4Cor e Forma:SolidPeso molecular:449.29Angiotensinogen (1-14), human
CAS:<p>Angiotensinogen (1-14), human,Liver-synthesized globulin. Precursor to angiotensin I.</p>Fórmula:C83H122N24O19Pureza:98%Cor e Forma:SolidPeso molecular:1760.01THX6
<p>THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.</p>Fórmula:C22H18Cl2N4O2Cor e Forma:SolidPeso molecular:441.31D-Amino acid oxidase
CAS:<p>D-Amino acid oxidase enzyme metabolizes and detoxifies exogenous D-amino acids, regulating D-serine in the brain.</p>Cor e Forma:SolidhCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Fórmula:C13H10FN3O4Peso molecular:291.0655317(R)-HETE
CAS:<p>Kidney sodium transport is partly controlled by 17-HETE, a CYP450 metabolite of arachidonic acid, with the (S) enantiomer inhibiting ATPase at 2 μM.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.473ARL67156 triethylamine
<p>ARL67156, a selective ecto-ATPase inhibitor, blocks NTPDase1, 3, and NPP1; used in calcific valve, asthma research. Ki: 11-18 μM.</p>Fórmula:C15H24Br2N5O12P3·3C6H15N)Cor e Forma:SolidPeso molecular:1154.23Phosphoramidon
CAS:<p>Phosphoramidon inhibits metallo-endopeptidase, endothelin-converting enzyme, and thermolysin; derived from Streptomyces tanashiensis culture.</p>Fórmula:C23H34N3O10PPureza:98%Cor e Forma:SolidPeso molecular:543.54''-C18 EGCG
<p>4''-C18 EGCG is an effective inhibitor of α-amylase and α-glucosidase, with IC50 values of 3.74 and 0.81 μM, respectively. This compound suppresses carbohydrate-hydrolyzing enzymes, reduces oxidative stress and inflammation, and exhibits anti-diabetic activity. Moreover, 4''-C18 EGCG downregulates pro-inflammatory cytokines and demonstrates cytotoxicity at 50 μM against primary human peripheral blood mononuclear cells (PBMC), as well as non-cancerous cell lines 3T3-L1 and HEK 293.</p>Fórmula:C40H54O11Cor e Forma:SolidPeso molecular:710.85Endoglycoceramidase II (EGCase II)
CAS:<p>EGCase II is an enzyme breaking down the glycan-ceramide bond in glycosphingolipids.</p>Cor e Forma:Solid18:0,22:6 PS sodium
CAS:<p>Sodium 18:0,22:6 phosphatidylserine (PS) is a lipid found within synaptic vesicles alongside cholesterol, utilized in metabolic research [1].</p>Fórmula:C46H77NNaO10PCor e Forma:SolidPeso molecular:858.07CP-610431
CAS:<p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>Fórmula:C30H37N3O2Cor e Forma:SolidPeso molecular:471.645DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Fórmula:C17H12ClF6N5O2Cor e Forma:SolidPeso molecular:467.753
