Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(269 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(32 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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Doxorubicinol
CAS:<p>Doxorubicinol is the major circulating metabolite of doxorubicin with antineoplastic acitivity.</p>Fórmula:C27H31NO11Cor e Forma:SolidPeso molecular:545.54DSPE-PEG
CAS:<p>DSPE-PEG: a phospholipid-polymer for stable, efficient drug delivery with longer circulation.</p>Fórmula:C45H90NO10PCor e Forma:SolidPeso molecular:835.63024DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Fórmula:C8H10N4SPureza:98%Cor e Forma:SoildPeso molecular:194.26BBOX-IN-1
<p>BBOX-IN-1 (compound 58) is a potent BBOX inhibitor with an IC50 of 0.02 μM, and it is applicable in research related to triple-negative breast cancer (TNBC).</p>Fórmula:C18H17N3O6SCor e Forma:SolidPeso molecular:403.41Tetrachlorocatechol
CAS:<p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>Fórmula:C6H2Cl4O2Pureza:96.68%Cor e Forma:SolidPeso molecular:247.89DSPE-PEG2000-pPB
<p>DSPE-PEG2000-pPB is a PEG compound comprised of DSPE and the cyclic oligopeptide (pPB). The pPB component exhibits a high binding affinity for PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB is utilizable for drug delivery applications.</p>Cor e Forma:Odour Solid2′,3′-Di-O-acetyl-5′-deoxy-5-fluorocytidine
CAS:<p>2'',3''-Di-O-acetyl-5''-deoxy-5-fuluro-D-cytidine is a derivative of capecitabine.</p>Fórmula:C13H16FN3O6Pureza:99.51%Cor e Forma:SolidPeso molecular:329.28Dihydrocarminomycin
CAS:<p>Dihydrocarminomycin is an anthracycline antibiotics.</p>Fórmula:C26H29NO10Pureza:98%Cor e Forma:SolidPeso molecular:515.515ACAT-IN-9
CAS:<p>ACAT-IN-9, derived from EP1236468A1 (example 207), is an ACAT inhibitor that suppresses NF-κB transcription.</p>Fórmula:C33H51N3O5SCor e Forma:SolidPeso molecular:601.85DSPE-PEG1000-NYZL1
<p>DSPE-PEG1000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to selectively bind to bladder cancer tissues and cells. This compound is applicable for drug delivery purposes.</p>Cor e Forma:Odour Solid2-Chlorophenylboronic acid
CAS:<p>2-Chlorophenylboronic acid: A monohalogenated phenylboronic acid used in drug synthesis and as a fatty acid amidase inhibitor.</p>Fórmula:C6H6BClO2Pureza:99.42%Cor e Forma:SolidPeso molecular:156.37(Z)-2-Octenoic acid
CAS:<p>Z-2-Octenoic acid, the Z-isomer of 2-Octenoic acid, is also known as trans-2-Octenoic acid and serves as a metabolite in Mucor species.</p>Fórmula:C8H14O2Cor e Forma:SolidPeso molecular:142.201-Palmitoyl Lysophosphatidic Acid
CAS:<p>1-Palmitoyl Lysophosphatidic Acid boosts antibiotics against P. aeruginosa by binding Ca2+ and Mg2+.</p>Fórmula:C19H39O7PPureza:98%Cor e Forma:SolidPeso molecular:410.48Hexasodium phytate
CAS:<p>Hexasodium phytate is used potentially to treat vascular calcification and calciphylaxis.</p>Fórmula:C6H12Na6O24P6Pureza:98%Cor e Forma:SolidPeso molecular:791.93Malate dehydrogenase
CAS:<p>Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .</p>Cor e Forma:Solid12-Hydroxynevirapine
CAS:<p>12-Hydroxynevirapine, major Nevirapine metabolite; non-toxic but liver/skin SULTs convert it to reactive 12-Sulphoxy-nevirapine.</p>Fórmula:C15H14N4O2Cor e Forma:SolidPeso molecular:282.3Motapizone
CAS:<p>Motapizone (NAT 05-239), a PDE3 inhibitor, moderates LPS-induced cytokine release and blocks platelet aggregation by boosting cAMP.</p>Fórmula:C12H12N4OSCor e Forma:SolidPeso molecular:260.321,2-POPS sodium salt
CAS:<p>1,2-POPS sodium salt is a lipid that can be used to synthesize artificial lipid membranes.</p>Fórmula:C40H75NNaO10PCor e Forma:SolidPeso molecular:783.99Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside
CAS:<p>Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside (pNP-G7) is a substrate for α-amylase, used to measure α-amylase activity.</p>Fórmula:C50H77NO38Cor e Forma:SolidPeso molecular:1300.13Aldose 1-epimerase
CAS:<p>Aldose 1-epimerase facilitates the conversion of α- to β-sugars like glucose, crucial for carbohydrate processing.</p>Cor e Forma:SolidParaherquamide E
CAS:<p>Fungal-derived paraherquamide E kills C. elegans and O. fasciatus, reduces T. colubriformis eggs in gerbils.</p>Fórmula:C28H35N3O4Cor e Forma:SolidPeso molecular:477.605N-Pivaloyl-L-tyrosine
CAS:<p>N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester.</p>Fórmula:C14H19NO4Cor e Forma:SolidPeso molecular:265.30LVGRQLEEFL (mouse) (TFA)
<p>G* peptide, also known as LVGRQLEEFL (mouse) TFA, is a segment corresponding to amino acids 113 to 122 ([113,122] apoJ) of apolipoprotein J.</p>Cor e Forma:Odour SolidMethoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:<p>Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3</p>Fórmula:C22H34N8O7Cor e Forma:SolidPeso molecular:522.55Captopril EP Impurity E
CAS:<p>Captopril EP Impurity E, an ACE inhibitor with antihypertensive properties, has an IC50 of 0.025 μM.</p>Fórmula:C9H15NO3Cor e Forma:SolidPeso molecular:185.22ZK53
CAS:<p>ZK53 is a mitochondrial casein hydrolysing protease P (HsClpP) activator that induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.</p>Fórmula:C19H20BrF2N3OPureza:97.8% - 99.36%Cor e Forma:SoildPeso molecular:424.28H-Tyr-Ala-OH
CAS:<p>Tyrosylalanine (H-Tyr-Ala-OH), a dipeptide comprising L-tyrosine and L-alanine, is referenced in studies [1] [2].</p>Fórmula:C12H16N2O4Pureza:99.74%Cor e Forma:SolidPeso molecular:252.2728-Epirapamycin
CAS:<p>28-Epirapamycin, an impurity of Rapamycin, serves as a potent and specific mTOR inhibitor, exhibiting an IC50 value of 0.1 nM in HEK293 cells [1].</p>Fórmula:C51H79NO13Cor e Forma:SolidPeso molecular:914.17Meproscillarin
CAS:<p>Meproscillarin is a glycoside with high bioavailability (about 70%) and an elimination independent of renal function.</p>Fórmula:C31H44O8Cor e Forma:SolidPeso molecular:544.68Enterostatin(human,mouse,rat)
CAS:<p>Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.</p>Fórmula:C21H36N8O6Pureza:98%Cor e Forma:SolidPeso molecular:496.569Olanzapine N-Oxide
CAS:<p>Olanzapine N-Oxide is a metabolite of Olanzapine which shows antipsychotic activity.</p>Fórmula:C17H20N4OSPureza:98.21%Cor e Forma:SolidPeso molecular:328.43DBPR-110
CAS:<p>DBPR-110: NS5A inhibitor, EC50 of 3.9 pM for HCV1b, SI >12.8 million; EC50 of 228.8 pM for HCV2a, SI >173,130.</p>Fórmula:C50H48N6O4S2Pureza:98%Cor e Forma:SolidPeso molecular:861.09Biotin-Vitamin B12
<p>Biotin-Vitamin B12, a biotinylated form, is crucial for brain, nervous system function, and blood formation.</p>Fórmula:C73H102CoN16O16PSCor e Forma:SolidPeso molecular:1581.66DSPE-PEG1000-CGKRK
<p>DSPE-PEG1000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is utilized for drug delivery.</p>Cor e Forma:Odour SolidN4-Acetylcytidine triphosphate
CAS:<p>N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .</p>Fórmula:C11H18N3O15P3Pureza:98%Cor e Forma:SolidPeso molecular:525.19hCAII/IX-IN-1
<p>hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.</p>Fórmula:C23H22N4O7S2Cor e Forma:SolidPeso molecular:530.573Picornain 3C
CAS:<p>Picornain 3C, a protease in picornaviruses, cleaves Gln-Gly bonds in poliovirus polyproteins and similar sites in others.</p>Cor e Forma:SolidHSP90-IN-30
<p>HSP90-IN-30 (compound 3e) inhibits the activity of the HSP90 molecular chaperone. Under hypoxic conditions, HSP90-IN-30 suppresses HIF-1 transcriptional activity with an IC50 value of 2.16 μM.</p>Fórmula:C20H39B12N4O2Peso molecular:499.41897Impurity F of Calcipotriol
CAS:<p>Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.</p>Fórmula:C39H68O3Si2Pureza:98%Cor e Forma:SolidPeso molecular:641.13Transketolase-IN-6
<p>Transketolase-IN-6 (Compound 6bj) serves as a lead compound for herbicides. It achieves approximately 80% root inhibition in redroot pigweed (Amaranthus retroflexus) and green foxtail (Setaria viridis). Moreover, Transketolase-IN-6 is an effective inhibitor of transketolase (TK).</p>Fórmula:C23H27ClN6OPeso molecular:438.19349hCYP3A4-IN-1
<p>hCYP3A4-IN-1 (compound C6) is a potent, orally active inhibitor of hCYP3A4, exhibiting IC50 values of 43.93 nM in human liver microsomes (HLMs) and 153.00 nM in</p>Cor e Forma:Odour SolidZ-Asp(OBzl)-OH
CAS:<p>Z-Asp(OBzl)-OH (N-Cbz-L-Aspartic acid 4-benzyl ester) is an aspartic acid derivative.</p>Fórmula:C19H19NO6Pureza:98.71%Cor e Forma:SolidPeso molecular:357.36NAMPT activator-7
<p>NAMPTactivator-7 (Compound 232) is an activator of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of less than 0.5 μM. It effectively stimulates NAMPT in U2OS cells, demonstrating a cellular EC50 of less than 0.5 μM.</p>Fórmula:C21H17ClN4O3Peso molecular:408.09892α-Glucosidase-IN-67
α-Glucosidase-IN-67 (compound 5k) is a potent inhibitor of α-glucosidase, exhibiting IC50 values of 0.31 µM for α-glucosidase and 4.51 µM for α-amylase. This compound shows potential for research in type 2 diabetes.Fórmula:C24H22BrN3O3SPeso molecular:511.056532,6-Diphenylpyridine
CAS:<p>2,6-Diphenylpyridine is toxic to MDA-MB-231 cells and has anticancer potential.</p>Fórmula:C17H13NPureza:99.21%Cor e Forma:SolidPeso molecular:231.29Pyruvate kinase
CAS:<p>Pyruvate kinase is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP [1] .</p>Cor e Forma:SolidMitochondrial respiration-IN-3
<p>Mitochondrial respiration-IN-3, a cell-permeable fluorine derivative of Dalfopristin, inhibits glioblastoma stem cell translation for cancer research.</p>Fórmula:C35H51FN4O7SCor e Forma:SolidPeso molecular:690.87Atrazine Mercapturate
CAS:<p>Atrazine mercapturate, a major atrazine metabolite from glutathione, is detectable in urine and linked to cancer, reproductive, and endocrine issues.</p>Fórmula:C13H22N6O3SCor e Forma:SolidPeso molecular:342.42DSPE-PEG2000-CCK8
<p>DSPE-PEG2000-CCK8 is a PEG compound comprising DSPE and Cholecystokinin-8 (CCK8). Cholecystokinin-8 exhibits peptide activity responsible for regulating gallbladder contractions and digestive system functions. DSPE-PEG2000-CCK8 is applicable for drug delivery.</p>Cor e Forma:Odour SolidNedosiran sodium
CAS:<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Cor e Forma:Solid
