Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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O-Desethyl Sildenafil
CAS:<p>O-Desethyl sildenafil is a metabolite of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1</p>Fórmula:C20H26N6O4SCor e Forma:SolidPeso molecular:446.53Sarcinapterin
CAS:<p>Sarcinapterin is a coenzyme isolated from Methanosarcina barkeri.</p>Fórmula:C35H48N7O19PCor e Forma:SolidPeso molecular:901.773HIV-1 inhibitor-58
<p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>Fórmula:C26H24N6O2Cor e Forma:SolidPeso molecular:452.51Saccharopine hydrochloride
<p>Saccharopine hydrochloride, from lysine degradation, disrupts mitochondria and hinders development.</p>Fórmula:C11H21ClN2O6Cor e Forma:SolidPeso molecular:312.75α-Glucosidase-IN-24
CAS:<p>α-Glucosidase-IN-24 (Compound 13), an α-Glucosidase inhibitor, exhibits an IC50 value of 451 μM and can be derived from Swertia kouitchensis [1].</p>Fórmula:C26H30O15Cor e Forma:SolidPeso molecular:582.51TNAP-IN-1
CAS:<p>TNAP-IN-1 is a specific inhibitor of tissue-nonspecific alkaline phosphatase (TNAP) and is utilized in studying diseases related to soft tissue calcification.</p>Fórmula:C17H16N2O4SPureza:99.03%Cor e Forma:SolidPeso molecular:344.392'-Rhamnoechinacoside
CAS:<p>2'-Rhamnoechinacoside is a naturally occurring compound sourced from Cistanche tubulosa.</p>Fórmula:C41H56O24Cor e Forma:SolidPeso molecular:932.9DOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Fórmula:C61H88N16O22S2Cor e Forma:SolidPeso molecular:1461.577β,25-Dihydroxycholesterol
CAS:<p>7β,25-Dihydroxycholesterol, an endogenous metabolite, functions as chemoattractants for immune cells that express EBI2 [1].</p>Fórmula:C27H46O3Cor e Forma:SolidPeso molecular:418.65(+)-Geodin
CAS:<p>(+)-Geodin, a fungal metabolite, boosts fibrinolysis in BAECs (50-150 μM) and glucose uptake in rat adipocytes (1-100 μg/ml).</p>Fórmula:C17H12Cl2O7Cor e Forma:SolidPeso molecular:399.18PLA2-IN-1
<p>PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.</p>Cor e Forma:Odour SolidATX inhibitor 7
CAS:<p>ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.</p>Fórmula:C21H22F3N7O2Cor e Forma:SolidPeso molecular:461.449COMT-IN-2
<p>COMT-IN-2 (compound 9) is the most potent inhibitor of COMT, exhibiting selective inhibition for brain (IC50=24 nM) and liver (IC50=81 nM) MB-COMT compared to the liver S-COMT isoform (IC50=620 nM).</p>Cor e Forma:Odour SolidMEY-003
<p>MEY-003, an Autotaxin (ATX) inhibitor, exhibits EC50 values of 460 nM for hATX-β and 1.09 μM for hATX-ɣ (analysis with LPC18:1), demonstrating its potency</p>Cor e Forma:Odour SolidDigalacturonic acid
CAS:<p>Digalacturonic acid, a pectin metabolite, aids in enzyme co-crystallization like proteinase K.</p>Fórmula:C12H18O13Cor e Forma:SolidPeso molecular:370.266-Ethyl-2,7-dimethoxyjuglone
CAS:<p>6-Ethyl-2,7-dimethoxyjuglone is a metabolite isolated from freshwater fungi [1] .</p>Fórmula:C14H14O5Cor e Forma:SolidPeso molecular:262.26Mannose 6 phosphate
CAS:Mannose 6-phosphate (M6P) features a type I integral membrane receptor.Fórmula:C6H13O9PPeso molecular:260.14Febuxostat sec-butoxy acid
CAS:<p>Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H16N2O3SCor e Forma:SolidPeso molecular:316.37LYP-IN-3
<p>LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway</p>Fórmula:C35H27NO6SPureza:98%Cor e Forma:SolidPeso molecular:589.66Erucic acid sodium
CAS:<p>Erucic acid sodium, a monounsaturated fatty acid (MUFA) extracted from the seeds of rapeseed, readily crosses the blood-brain barrier (BBB). It normalizes the accumulation of long-chain fatty acids in the brain, enhances cognitive function, and effectively prevents dementia.</p>Fórmula:C22H42NaO2Cor e Forma:SolidPeso molecular:361.56Teprotide
CAS:<p>Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].</p>Fórmula:C53H76N14O12Cor e Forma:SolidPeso molecular:1101.26ChAT IN-1
<p>ChAT IN-1 is a selective inhibitor of Choline Acetyltransferase (ChAT) that is utilized in studying mechanisms related to non-neuronal ChAT overexpression in cancers such as colon cancer and lung cancer, as well as in research concerning Alzheimer's disease (AD).</p>Fórmula:C21H15N3O2Cor e Forma:SolidPeso molecular:341.36Omfiloctocog alfa
CAS:<p>Omfiloctocog alfa (SCT-800) is a recombinant FVIII for Hemophilia A research.</p>Cor e Forma:LiquidCarbolactone
CAS:<p>Carbolactone is a biologically active metabolite from fungi [1] .</p>Fórmula:C24H36O3Cor e Forma:SolidPeso molecular:372.54Cellohexaose
CAS:<p>Cellohexaose, a cellulose-derived polymer, comprises at least two β(1-4) linked D-glucose units.</p>Fórmula:C36H62O31Cor e Forma:SolidPeso molecular:990.86N-Decanoyl p-Nitroaniline
CAS:<p>DepNA, a nitroaniline fatty acid amide, measures FAAH activity by releasing yellow dye p-nitroaniline upon exposure, detectable via spectrophotometer.</p>Fórmula:C16H24N2O3Cor e Forma:SolidPeso molecular:292.379PPARγ agonist 15
<p>PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.</p>Fórmula:C21H16N4O3S2Cor e Forma:SolidPeso molecular:436.51N-Desmethyl imatinib mesylate
CAS:<p>Norimatinib mesylate, N-Desmethyl imatinib metabolite, inhibits v-Abl, c-Kit, PDGFR.</p>Fórmula:C29H33N7O4SCor e Forma:SolidPeso molecular:575.68TEI-9648
CAS:<p>TEI-9648: Potent, specific VDR antagonist, blocks 1α,25(OH)2D3 effects, may aid bone metabolism study.</p>Fórmula:C27H38O4Cor e Forma:SolidPeso molecular:426.597Febuxostat n-butyl isomer
CAS:<p>Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H16N2O3SCor e Forma:SolidPeso molecular:316.38Cholesteryl arachidonate
CAS:<p>Cholesteryl arachidonate is a human endogenous metabolite.</p>Fórmula:C47H76O2Pureza:98%Cor e Forma:SolidPeso molecular:673.11ecMetAP-IN-1
CAS:<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Fórmula:C13H11N3Pureza:99.34%Cor e Forma:SolidPeso molecular:209.25Mycophenolate mofetil hydrochloride
CAS:<p>Mycophenolate Mofetil: Non-competitive, selective inhibitor of IMP dehydrogenase I/II, IC50: 39/27 nM.</p>Fórmula:C23H32ClNO7Pureza:98%Cor e Forma:SolidPeso molecular:469.96Acyl coenzyme A synthetase
CAS:<p>ACS activates fatty acids for lipid metabolism and the TCA cycle.</p>Cor e Forma:SolidDihomo-γ-Linolenic acid methyl ester
CAS:<p>Dihomo-γ-Linolenic acid methyl ester is the methyl ester form of Dihomo-γ-Linolenic acid which has anti-inflammatory and anti-proliferative effects.</p>Fórmula:C21H36O2Pureza:≥98%Cor e Forma:SolidPeso molecular:320.51IDO1-IN-7
CAS:<p>IDO1-IN-7 is a potent IDO1 inhibitor with a 6.1 nM IC50 and immunomodulatory effects for cancer research.</p>Fórmula:C22H19ClFN3O3Cor e Forma:SolidPeso molecular:427.86PFKFB3-IN-2
CAS:<p>PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.</p>Fórmula:C14H11NO7SPureza:99.12%Cor e Forma:SolidPeso molecular:337.39(S)-HpOTrE
CAS:<p>9(S)-HpOTrE, a product of 5-LO on α-linolenic acid, transforms into colnelenic acid and 9,16-dihydroperoxy acid; it inactivates LOs through epoxide formation.</p>Fórmula:C18H30O4Cor e Forma:SolidPeso molecular:310.43410-FTHF
CAS:<p>10-FTHF is a donor of formyl groups in anabolism used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.</p>Fórmula:C20H23N7O7Cor e Forma:SolidPeso molecular:473.44ACAT-IN-7
CAS:<p>ACAT-IN-7 inhibits ACAT enzyme; blocks NF-κB mediated transcription.</p>Fórmula:C32H49N3O5SCor e Forma:SolidPeso molecular:587.82Desoxycarbadox
CAS:<p>Desoxycarbadox, derived from Carbadox, is a quinoxaline-di-N-oxide antibiotic compound.</p>Fórmula:C11H10N4O2Cor e Forma:SolidPeso molecular:230.227Leucomyosuppressin
CAS:<p>Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.</p>Fórmula:C59H84N16O15Pureza:98%Cor e Forma:SolidPeso molecular:1257.418Adenosylhomocysteinase
CAS:<p>SAHH, an enzyme, reversibly converts SAH into adenosine and L-homocysteine, and may predict HBV-LC outcomes.</p>Fórmula:C14H13N3O2S2Cor e Forma:SolidPeso molecular:319.04492Triethyl phosphate
CAS:<p>Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".</p>Fórmula:C6H15O4PPureza:98%Cor e Forma:Clear LiquidPeso molecular:182.16Mefox
CAS:<p>Mefox is a bioactive chemical.</p>Fórmula:C20H23N7O7Cor e Forma:SolidPeso molecular:473.44N-Pivaloyl-L-tyrosine
CAS:<p>N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester.</p>Fórmula:C14H19NO4Cor e Forma:SolidPeso molecular:265.30Remdesivir de(ethylbutyl 2-aminopropanoate)
CAS:<p>Remdesivir impurity with antiviral activity; EC50: SARS-CoV/MERS-CoV 74 nM, murine hepatitis virus 30 nM. Effective against COVID-19 in vitro.</p>Fórmula:C18H18N5O7PCor e Forma:SolidPeso molecular:447.34CM121
CAS:<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Fórmula:C24H17FN4O3SCor e Forma:SolidPeso molecular:460.48Aldose 1-epimerase
CAS:<p>Aldose 1-epimerase facilitates the conversion of α- to β-sugars like glucose, crucial for carbohydrate processing.</p>Cor e Forma:SolidCrelosidenib
CAS:<p>Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.</p>Fórmula:C28H36N6O3Pureza:98.54%Cor e Forma:SolidPeso molecular:504.62
