Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(270 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(97 produtos)
- Lipídio(59 produtos)
- Lipoxigenase(125 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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Setosusin
CAS:<p>Setosusin, a meroterpenoid from C. setosus, reduces Aβ-induced neurotoxicity in PC12 cells (EC50 = 112.6 μM).</p>Fórmula:C29H38O8Cor e Forma:SolidPeso molecular:514.615Zaragozic acid D(2)
CAS:<p>Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>Fórmula:C36H50O14Pureza:98%Cor e Forma:SolidPeso molecular:706.77Fumiquinazoline D
CAS:<p>Fumiquinazoline D, from A. fumigatus, inhibits Gram-positive/negative bacteria (MIC 8-16 μg/ml) and F. solani, C. albicans (MIC 32, 64 μg/ml).</p>Fórmula:C24H21N5O4Cor e Forma:SolidPeso molecular:443.463(-)-Jasmonoyl-L-isoleucine
CAS:<p>(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile), an enantiomer of (+)-JA-L-Ile [1], is an inactive endogenous hormone.</p>Fórmula:C18H29NO4Cor e Forma:SolidPeso molecular:323.43IYPTNGYTR acetate
<p>IYPTNGYTR acetate, a deamidation-sensitive peptide derived from Trastuzumab, is a suitable tool for monitoring the metabolism of Trastuzumab in vivo [1].</p>Cor e Forma:LiquidCH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS:<p>CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].</p>Fórmula:C27H42N8O9Pureza:98%Cor e Forma:SolidPeso molecular:622.67Diglycyl-histidine
CAS:<p>Diglycyl-histidine is a tripeptide complexed with cupric ion designed to mimic specific Cu(II) transport site of ascorbate on albumin molecule.</p>Fórmula:C10H15N5O4Cor e Forma:SolidPeso molecular:269.26β-1,3-Galactosyltransferase (CgtB)
CAS:<p>CgtB enzyme, needed for GM1-like LOS SIAL, catalyzes galactose addition in biochemical studies.</p>Cor e Forma:Solid4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone
CAS:<p>4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolism of yangonin, a major styryl lactone from Piper methysticum.</p>Fórmula:C14H12O5Pureza:99.67%Cor e Forma:SoildPeso molecular:260.24DSPE-PEG5000-LTLRWVGLMS
<p>DSPE-PEG5000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). Chondroitin sulfate proteoglycan NG2 serves as a receptor for LLRWVGLMS. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG5000-LTLRWVGLMS can be utilized for drug delivery.</p>Cor e Forma:Odour SolidPROTAC RAR Degrader-1
CAS:<p>PROTAC RAR Degrader-1, an RAR degrader, consists of a cIAP1 ligand binding group, a linker, and an RAR ligand binding group.</p>Fórmula:C51H72N4O11Pureza:98%Cor e Forma:SolidPeso molecular:917.14DSPE-PEG5000-MPG
<p>DSPE-PEG5000-MPG is a PEG compound composed of DSPE and a peptide carrier (MPG). MPG is derived from the nuclear localization sequence (NLS) of the SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. This compound effectively delivers short oligonucleotides into cells independently of the endosomal pathway.</p>Cor e Forma:Odour SolidFumonisin B2
CAS:<p>Fumonisin B2, from Fusarium moniliforme in grains, blocks ceramide synthase, disrupting sphingolipid biosynthesis.</p>Fórmula:C34H59NO14Pureza:98%Cor e Forma:SolidPeso molecular:705.83Butyrolactone II
CAS:<p>Butyrolactone II is a useful organic compound for research related to life sciences. The catalog number is T124034 and the CAS number is 87414-44-6.</p>Fórmula:C19H16O7Cor e Forma:SolidPeso molecular:356.33GP4G
CAS:<p>GP4G, from Artemia salina cysts, regulates epithelial cells & hair growth.</p>Fórmula:C20H28N10O21P4Cor e Forma:SolidPeso molecular:868.39Cortisol sulfate
CAS:<p>Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol . Cortisol sulfate is a specific ligand for intracellular transcortin [1] [2] [3] .</p>Fórmula:C21H30O8SCor e Forma:SolidPeso molecular:442.52α-Amylase/α-Glucosidase-IN-3
<p>α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM</p>Fórmula:C23H14Cl4N6O2SPureza:98%Cor e Forma:SolidPeso molecular:580.27Nor-Acetildenafil
CAS:<p>Nor-Acetildenafil is a derivative of Acetildenafil, a synthetic phosphodiesterase inhibitor.</p>Fórmula:C24H32N6O3Cor e Forma:SolidPeso molecular:452.55Largazole
CAS:<p>Largazole is a potent and selective histone deacetylase (HDAC) inhibitor and antiproliferative agent from Symploca.</p>Fórmula:C29H42N4O5S3Cor e Forma:SolidPeso molecular:622.86PTP1B-IN-14
CAS:<p>PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50)</p>Fórmula:C27H19N5O3S4Cor e Forma:SolidPeso molecular:589.73PDE4-IN-4
CAS:<p>PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment of</p>Fórmula:C36H37Cl2N3O7SCor e Forma:SolidPeso molecular:726.675-NH2-Baicalein
CAS:<p>5-NH2-Baicalein, an aminated metabolite of Baicalein, can be utilized for researching ammonia and ammonia-associated chronic diseases [1].</p>Fórmula:C15H11NO4Cor e Forma:SolidPeso molecular:269.25α-2,3-Sialyltransferase (PmST3)
CAS:<p>PmST3 is a beta-galactoside enzyme adding sialic acid to glycoproteins and glycolipids.</p>Cor e Forma:SolidNinerafaxstat
CAS:<p>Ninerafaxstat shifts metabolism to glucose, boosts mitochondrial function, and inhibits cancer growth.</p>Fórmula:C22H29N3O5Pureza:98%Cor e Forma:SolidPeso molecular:415.48Probestin
CAS:<p>Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.</p>Fórmula:C26H38N4O6Pureza:98%Cor e Forma:SolidPeso molecular:502.60α-1,3/4-Fucosyltransferase (α1,3/4FucT)
CAS:<p>alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (Hp3/4FT) can be found in Helicobacter pylori .</p>Cor e Forma:Solid1-Palmitoyl Lysophosphatidic Acid
CAS:<p>1-Palmitoyl Lysophosphatidic Acid boosts antibiotics against P. aeruginosa by binding Ca2+ and Mg2+.</p>Fórmula:C19H39O7PPureza:98%Cor e Forma:SolidPeso molecular:410.48FABP4-IN-4
<p>FABP4-IN-4 (Compound 30) is an orally effective inhibitor of FABP, with an IC50 value of 1.18 μM against FABP1. In a mouse model of diet-induced obesity, FABP4-IN-4 improves glucose tolerance, reduces levels of blood sugar, lipids, and liver inflammation markers, alleviates hepatic steatosis, and exhibits anti-inflammatory activity.</p>Cor e Forma:Odour SolidNicotinic Acid Adenine Dinucleotide
CAS:<p>Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthase</p>Fórmula:C21H26N6O15P2Cor e Forma:SoildPeso molecular:664.41Phytosterols
CAS:<p>Phytosterols found in algae have anti-cancer activity and are used in the study of cardiovascular diseases and cancer.</p>Pureza:98%Cor e Forma:SolidGalactonic acid
CAS:<p>Galactonic acid, derived from galactose metabolism, is converted from galactonolactone.</p>Fórmula:C6H12O7Cor e Forma:SolidPeso molecular:196.165-hydroxy Omeprazole
CAS:<p>5-hydroxy omeprazole, major omeprazole metabolite, formed by CYP2C19, affects gastric H+/K+ pump inhibition.</p>Fórmula:C17H19N3O4SCor e Forma:SolidPeso molecular:361.42ERAP1-IN-3
<p>ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.</p>Fórmula:C22H22N2O4SCor e Forma:SolidPeso molecular:410.49IPI-9119
CAS:<p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>Fórmula:C24H19F2N5O5Pureza:99.81%Cor e Forma:SolidPeso molecular:495.43Crotonyl-CoA
CAS:<p>Crotonyl-CoA: key in butyric acid fermentation, lysine and tryptophan metabolism, crucial for fatty and amino acid processing.</p>Fórmula:C25H40N7O17P3SCor e Forma:SolidPeso molecular:835.615A2-SC8 TFA
<p>5A2-SC8 TFA is an ionizable amino lipid used in lipid nanoparticles (LNPs), offering high delivery potential and low in vivo toxicity. It effectively delivers small RNAs, such as siRNA and miRNA, to tumor cells. Moreover, 5A2-SC8 TFA LNPs provide unique delivery paths for RNA within the liver, enhancing therapeutic outcomes in cancer models.</p>Cor e Forma:Odour SolidIsoglycycoumarin
CAS:<p>Isoglycycoumarin, a flavonoid derived from the roots of Glycyrrhiza uralensis, serves as a highly selective probe for human cytochrome P450 2A6.</p>Fórmula:C21H20O6Pureza:98%Cor e Forma:SolidPeso molecular:368.38Creatine riboside
CAS:<p>Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.</p>Fórmula:C9H17N3O6Pureza:98%Cor e Forma:SolidPeso molecular:263.25DSPE-PEG2000-CGKRK
<p>DSPE-PEG2000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is suitable for use in drug delivery.</p>Cor e Forma:Odour SolidPDE11A4-IN-1
<p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>Cor e Forma:Odour SolidSalinosporamide C
CAS:<p>Salinosporamide C is a decarboxylated pyrrole analogue isolated from the marine Actinomycete Salinispora tropica.</p>Fórmula:C14H18ClNO3Cor e Forma:SolidPeso molecular:283.75Ilexsaponin B2
CAS:<p>Ilexsaponin B2 is a natural product for research related to life sciences. The catalog number is TJS0502 and the CAS number is 108906-69-0.</p>Fórmula:C47H76O17Pureza:99.72%Cor e Forma:SolidPeso molecular:913.1Raloxifene 6,4'-Bis-β-D-glucuronide
CAS:<p>Raloxifene 6,4'-Bis-β-D-glucuronide is a Raloxifene metabolite. Raloxifene is a selective antagonist of estrogen receptor for the prevention of osteoporosis.</p>Fórmula:C40H43NO16SPureza:98%Cor e Forma:SolidPeso molecular:825.83α-Hydroxyglutaric Acid Lithium
<p>α-Hydroxyglutaric Acid Lithium is an α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase inhibitor of ATP synthase.</p>Fórmula:C5H6Li2O5Pureza:≥98%Cor e Forma:SoildPeso molecular:159.98(S)-ICMT-IN-3
<p>'(S)-ICMT-IN-3 (compound ent 1-27) is an ICMT inhibitor with an IC50 value of 0.23 μM [1].'</p>Cor e Forma:Odour Solid2,4-Dimethylquinoline
CAS:<p>2,4-Dimethylquinoline is a potential CYP1A2 inhibitor , and it also exhibits weak inhibitory activity against CYP2A5, CYP2A6, and CYP2B6.</p>Fórmula:C11H11NPureza:99.81%Cor e Forma:SolidPeso molecular:157.21Vitamin K5
CAS:<p>Vitamin K5, a photosensitizer & antimicrobial, inhibits PKM2, PKM1 & PKL, induces apoptosis in colon cells, and preserves food & medicine.</p>Fórmula:C11H11NOCor e Forma:SolidPeso molecular:173.21NGR peptide
CAS:<p>Cell-penetrating peptide</p>Fórmula:C20H36N10O8S2Pureza:98%Cor e Forma:SolidPeso molecular:608.69DSPE-PEG1000-ESBP
<p>DSPE-PEG1000-ESBP is a PEG compound composed of DSPE and an E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Cor e Forma:Odour SolidSeocalcitol
CAS:<p>Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).</p>Fórmula:C30H46O3Pureza:98%Cor e Forma:SolidPeso molecular:454.68
