Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(41 produtos)
- Aminopeptidase(67 produtos)
- CETP(18 produtos)
- Anidrase carbónica(178 produtos)
- Caseína quinase(130 produtos)
- DHFR(33 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(271 produtos)
- FAAH(64 produtos)
- FXR(58 produtos)
- Factor Xa(80 produtos)
- Sintase de Ácidos graxos(33 produtos)
- Ferroptose(215 produtos)
- GR(3 produtos)
- GSNOR(3 produtos)
- Glucoquinase(54 produtos)
- HIF/HIF Prolil-Hidroxilase(142 produtos)
- HMG-CoA Reductase(33 produtos)
- Hidroxilase(30 produtos)
- IDO(82 produtos)
- LDL(8 produtos)
- Lipase(98 produtos)
- Lipídio(58 produtos)
- Lipoxigenase(124 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(36 produtos)
- P450(6 produtos)
- PAI-1(25 produtos)
- PDE(166 produtos)
- PED(1 produtos)
- PKM(15 produtos)
- PPAR(164 produtos)
- Fosfolipase(82 produtos)
- ROR(42 produtos)
- Receptor de Retinóide(29 produtos)
- SGK(11 produtos)
- Tiorredoxina(12 produtos)
- Transferase(30 produtos)
- Tansportador(42 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 8626 produtos de "Metabolismo"
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BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Fórmula:C44H52N8O5Cor e Forma:SolidPeso molecular:772.93DF-461
CAS:<p>DF-461 is an inhibitor of squalene synthase.</p>Fórmula:C20H14Cl2F3N3O4Cor e Forma:SolidPeso molecular:488.24HSP90-IN-30
<p>HSP90-IN-30 (compound 3e) inhibits the activity of the HSP90 molecular chaperone. Under hypoxic conditions, HSP90-IN-30 suppresses HIF-1 transcriptional activity with an IC50 value of 2.16 μM.</p>Fórmula:C20H39B12N4O2Peso molecular:499.418979-PAHPA
CAS:<p>9-PAHPA, a fatty acid ester of hydroxy fatty acid (FAHFA), belongs to a recently identified family of endogenous lipids known for their antidiabetic and anti-</p>Fórmula:C32H62O4Cor e Forma:SolidPeso molecular:510.83Cyclosporin A-Derivative 3
CAS:<p>Cyclosporin A-Derivative 3 is a derivative of Cyclosporin A with calcineurin inhibition [1] .</p>Fórmula:C63H111N11O12Cor e Forma:SolidPeso molecular:1214.62α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Fórmula:C25H22N6OS2Cor e Forma:SolidPeso molecular:486.61sPLA2 inhibitor 3
sPLA2 inhibitor 3 (Compound 6c) functions as a potent α-glucosidase inhibitor (IC50= 0.0953 µM) and has potential applications in diabetes research.Fórmula:C22H16F6N6O4S2Cor e Forma:SolidPeso molecular:606.52ROS-IN-3
ROS-IN-3 (compound x38) is an inhibitor of ROS and is utilized in neuro-related research.Fórmula:C25H20F2N2O4Cor e Forma:SolidPeso molecular:450.4321-Deoxy Cortisone
CAS:<p>21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.</p>Fórmula:C21H28O4Cor e Forma:SolidPeso molecular:344.44Cytoglobosin C
CAS:<p>Cytoglobosin C, a derivative of cytochalasan, demonstrates significant cytotoxic effects on SGC-7901 and A549 cell lines, with an inhibitory concentration (IC50</p>Fórmula:C32H38N2O5Cor e Forma:SolidPeso molecular:530.65Pseudoerythromycin A enol ether
CAS:<p>Pseudoerythromycin A enol ether, a non-antibiotic erythromycin degradation product, serves as a standard in stability studies.</p>Fórmula:C37H65NO12Cor e Forma:SolidPeso molecular:715.91ACAT-IN-10 dihydrochloride
CAS:<p>ACAT-IN-10 dihydrochloride, from EP1236468A1 example 197, inhibits acyl-CoA: cholesterol acyltransferase and reduces NF-κB transcription.</p>Fórmula:C35H58Cl2N4O5SCor e Forma:SolidPeso molecular:717.83LQ-38
<p>LQ-38 is an orally active, soluble epoxide hydrolase (sEH) inhibitor with an IC50 value of 5.2 nM. It has shown anti-inflammatory activity in rat foot edema models and in mouse models of acute pancreatitis, and exhibits analgesic effects in acetic acid-induced mouse writhing models.</p>Fórmula:C42H68N2O9Cor e Forma:SolidPeso molecular:745.00Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:<p>Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3</p>Fórmula:C22H34N8O7Cor e Forma:SolidPeso molecular:522.55O-Demethyl Lenvatinib hydrochloride
<p>O-Demethyl Lenvatinib HCl is a Lenvatinib metabolite; an oral inhibitor targeting VEGFR, FGFR, PDGFR, KIT, RET with antitumor properties.</p>Fórmula:C20H18Cl2N4O4Cor e Forma:SolidPeso molecular:449.29Hydroxy ritonavir
CAS:<p>Hydroxy ritonavir, a metabolite of ritonavir, functions as an inhibitor of the HIV protease, thereby serving as a treatment for HIV infection and AIDS [1].</p>Fórmula:C37H48N6O6S2Cor e Forma:SolidPeso molecular:736.94DSPE-PEG1000-APRPG
<p>DSPE-PEG1000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is applicable for drug delivery.</p>Cor e Forma:Odour SolidCasein kinase 1δ-IN-15
CAS:<p>Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].</p>Fórmula:C19H17FN6OCor e Forma:SolidPeso molecular:364.38Teprotide
CAS:<p>Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].</p>Fórmula:C53H76N14O12Cor e Forma:SolidPeso molecular:1101.26Galactosylhydroxylysine hydrochloride
<p>Galactosylhydroxylysine hydrochloride, found in bone collagen, is higher in metabolic bone loss due to resorption.</p>Fórmula:C12H25ClN2O8Cor e Forma:SolidPeso molecular:360.79tetranor-12(S)-HETE
CAS:<p>12(S)-HETE, from arachidonic acid via 12-lipoxygenase, is found in platelets and leukocytes, aids tumor cell adhesion, with a derivative used in research.</p>Fórmula:C16H26O3Cor e Forma:SolidPeso molecular:266.381Bam 12P acetate
<p>Bam 12P acetate is the putative enkephalin precursor in bovine adrenal, pituitary, and hypothalamus.</p>Fórmula:C64H101N21O18SPureza:98.84%Cor e Forma:SolidPeso molecular:1484.68O-desmethyl Mebeverine acid
CAS:<p>O-desmethyl Mebeverine acid is a metabolite of Mebeverine.</p>Fórmula:C15H23NO3Pureza:98%Cor e Forma:SolidPeso molecular:265.35N-Nitrosoglyphosate sodium
CAS:<p>N-Nitrosoglyphosate sodium, a nitrosamine degradation product and synthetic impurity of glyphosate herbicide [1], is a chemical compound resulting from the</p>Fórmula:C3H6N2NaO6PCor e Forma:SolidPeso molecular:220.056,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone
CAS:<p>Compound 1, 6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone, is an anthraquinone α-glucosidase inhibitor with an IC50 of 185 μM, and it can be isolated</p>Fórmula:C18H16O7Pureza:98%Cor e Forma:SolidPeso molecular:344.32Sofosbuvir impurity E
<p>Sofosbuvir impurity E, a less active byproduct, inhibits HCV RNA replication with potent anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45LYP-IN-4
<p>LYP-IN-4 (compound D14), a reversible and selective lymphotyrosine phosphatase (LYP) inhibitor (Ki=1.34 μM, IC50=3.52μM), regulates TCR signaling, increases PD-</p>Fórmula:C29H21ClN2O8SPureza:98%Cor e Forma:SolidPeso molecular:593N6-Isopentenyladenosine
CAS:<p>N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.</p>Fórmula:C15H21N5O4Pureza:97.13% - 99.69%Cor e Forma:SolidPeso molecular:335.36Human Endogenous Metabolite Library
<p>A collection of xnum selected human endogenous metabolites for high throughput and high content screening.</p>Cor e Forma:Odour SolidImpurity F of Calcipotriol
CAS:<p>Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.</p>Fórmula:C39H68O3Si2Pureza:98%Cor e Forma:SolidPeso molecular:641.13Human Endogenous Metabolite Compound Library Plus
<p>A unique collection of xnum endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.</p>Cor e Forma:Odour SolidO-Desisobutyl-O-n-propyl Febuxostat
CAS:<p>O-Desisobutyl-O-n-propyl Febuxostat, an xanthine oxidase inhibitor.</p>Fórmula:C15H14N2O3SCor e Forma:SolidPeso molecular:302.35ACAT-IN-9
CAS:<p>ACAT-IN-9, derived from EP1236468A1 (example 207), is an ACAT inhibitor that suppresses NF-κB transcription.</p>Fórmula:C33H51N3O5SCor e Forma:SolidPeso molecular:601.85γ-Glu-Phe
CAS:<p>γ-Glu-Phe (γ-Glutamylphenylalanine) is a γ-3 glutamyl dipeptide found in sourdough.it is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae</p>Fórmula:C14H18N2O5Pureza:98%Cor e Forma:SolidPeso molecular:294.3L-Aspartic acid (Standard)
CAS:<p>L-Aspartic acid (Standard) is a standard material used in the analysis of L-Aspartic acid, commonly referenced in its research and analysis.</p>Fórmula:C4H7NO4Pureza:99.79%Cor e Forma:White SolidPeso molecular:133.1GLUT inhibitor-1
CAS:<p>GLUT inhibitor-1: oral, targets GLUT1/3 (IC50: 242/179 nM), for cancer/autoimmune research.</p>Fórmula:C32H35N7O2Pureza:98.12%Cor e Forma:SolidPeso molecular:549.67FA-Ala-Arg
CAS:<p>FA-Ala-Arg is a dipeptide featuring a furylacryloyl group that degrades to yield arginine.</p>Fórmula:C16H23N5O5Pureza:98%Cor e Forma:SolidPeso molecular:365.38AP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Fórmula:C31H44ClFN8O3Pureza:98%Cor e Forma:SolidPeso molecular:631.18FXIa-IN-15
CAS:<p>FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.</p>Fórmula:C32H23ClF3N7O4Cor e Forma:SolidPeso molecular:662.022-Methyl-1-naphthol
CAS:<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Fórmula:C11H10OPureza:98.33%Cor e Forma:SolidPeso molecular:158.2Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Cor e Forma:LiquidPeso molecular:145.55 kDaComplement factor I
CAS:<p>Complement factor I, a serine protease, attenuates complement activity both in the fluid phase and on cell surfaces, working alongside cofactors such as factor</p>Pureza:98%Cor e Forma:SolidhCYP3A4-IN-1
<p>hCYP3A4-IN-1 (compound C6) is a potent, orally active inhibitor of hCYP3A4, exhibiting IC50 values of 43.93 nM in human liver microsomes (HLMs) and 153.00 nM in</p>Cor e Forma:Odour SolidPenicillide
CAS:<p>Penicillide: fungal metabolite, inhibits calpain 2/ACAT (IC50 = 7.1/22.9 μM), blocks oxytocin receptors (IC50 = 67 μM), stops RNA synthesis in P388 cells.</p>Fórmula:C21H24O6Cor e Forma:SolidPeso molecular:372.417L-Proline-15N
CAS:<p>L-Proline-15N is an isotopically labeled amino acid suitable for metabolic research, aiding in the exploration of amino acid metabolism pathways and mechanisms.</p>Fórmula:C5H9NO2Cor e Forma:SolidPeso molecular:116.12Lysophosphatidylethanolamines (egg)
CAS:<p>Lysophosphatidylethanolamines (egg) are the partial hydrolysis products of phosphatidylethanolamine.</p>Cor e Forma:SolidLYS006 hydrochloride
CAS:<p>LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 value of 2 nM. It is applicable in the study of inflammatory and autoimmune diseases. For further details, please refer to compound 29 in patent document WO2015092740A1.</p>Fórmula:C16H15Cl2FN6O3Cor e Forma:SolidPeso molecular:429.23Hydroxocobalamin
CAS:<p>Hydroxocobalamin (Vitamin B12a) is a naturally occurring, injectable form of vitamin B12 used as a dietary supplement to treat B12 deficiency, including</p>Fórmula:C62H89CoN13O15PPureza:98%Cor e Forma:SolidPeso molecular:1346.36KR-27425
<p>Compound 13, an AChE activator 1, is a non-pyridinium oxime that reactivates paraoxon-inhibited acetylcholinesterase (AChE) [1].</p>Pureza:98%Cor e Forma:Odour SolidIlexoside O
CAS:<p>Ilexoside O, a root-derived triterpene saponin, modestly blocks XOD with an IC50 of 53.05 μM.</p>Fórmula:C53H86O22Cor e Forma:SolidPeso molecular:1075.249
