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Metabolismo

Metabolismo

Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.

Subcategorias de "Metabolismo"

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Foram encontrados 8595 produtos de "Metabolismo"

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  • 2H-Cho-Arg (trifluoroacetate salt)

    CAS:
    <p>2H-Cho-Arg, a cationic lipid, enables gene delivery into cells and shows cytotoxicity at 92.7 μg/ml.</p>
    Fórmula:C43H73F6N5O7
    Cor e Forma:Solid
    Peso molecular:886.06
  • 2'-Rhamnoechinacoside

    CAS:
    <p>2'-Rhamnoechinacoside is a naturally occurring compound sourced from Cistanche tubulosa.</p>
    Fórmula:C41H56O24
    Cor e Forma:Solid
    Peso molecular:932.9
  • Venetoclax N-oxide

    CAS:
    <p>Venetoclax N-oxide is a byproduct of potent, oral Bcl-2 inhibitor Venetoclax (ABT-199/GDC-0199) with Ki &lt;0.01 nM.</p>
    Fórmula:C45H50ClN7O8S
    Cor e Forma:Solid
    Peso molecular:884.44
  • hCAIX-IN-17


    <p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>
    Fórmula:C19H18N2O3S
    Cor e Forma:Solid
    Peso molecular:354.42
  • DSPE-PEG5000-ANG


    <p>DSPE-PEG5000-ANG is a PEGylated compound formed by DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficacy to LRP1 and has been utilized for targeting glioma delivery. DSPE-PEG5000-ANG is applicable in drug delivery.</p>
    Cor e Forma:Odour Solid
  • CNBCA


    <p>CNBCA, a selective and potent competitive inhibitor of the SHP2 enzyme, exhibits an IC50 value of 0.87 μM.</p>
    Fórmula:C26H34O5
    Cor e Forma:Solid
    Peso molecular:426.55
  • 2-Ethylnaphthalene

    CAS:
    <p>2-Ethylnaphthalene exhibits inhibitory activity against CYP1A2, CYP2A5, and CYP2A6 and can be used in biochemical experiments and drug synthesis.</p>
    Fórmula:C12H12
    Cor e Forma:Solid
    Peso molecular:156.22
  • β-Tetralone

    CAS:
    <p>β-Tetralone (2-Tetralone) is a vital drug synthesis precursor with complex pharmacological properties in combating neurological disorders. Cost-effective and quality-assured.</p>
    Fórmula:C10H10O
    Pureza:97.26% - 99.18%
    Cor e Forma:Clear To Yellow Liquid
    Peso molecular:146.19
  • ATX inhibitor 7

    CAS:
    <p>ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.</p>
    Fórmula:C21H22F3N7O2
    Cor e Forma:Solid
    Peso molecular:461.449
  • ACAT-IN-8

    CAS:
    <p>ACAT-IN-8 is an ACAT inhibitor which regulates cholesterol and blocks NF-κB mediated transcription.</p>
    Fórmula:C32H49N3O5S
    Cor e Forma:Solid
    Peso molecular:587.82
  • SHP2-IN-36


    <p>SHP2-IN-36 (Compound B8) is an allosteric inhibitor of SHP2 with an IC50 of 9.0 nM, and it exhibits an IC50 of 40 nM against p-ERK. Moreover, SHP2-IN-36 demonstrates significant antitumor activity in the KYSE520 xenograft mouse model and is applicable for research in the field of antitumor studies.</p>
    Cor e Forma:Odour Solid
  • (24R)-MC 976

    CAS:
    <p>(24R)-MC 976 is a derivative of Vitamin D3.</p>
    Fórmula:C27H42O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:414.62
  • 10(S),17(S)-DiHDHA

    CAS:
    <p>Protectin D1, or neuroprotectin D1 in neurons, is anti-inflammatory. 10(S),17(S)-DiHDHA, also PDX, differs in structure and inhibits neutrophils and platelets.</p>
    Fórmula:C22H32O4
    Cor e Forma:Solid
    Peso molecular:360.494
  • (24S)-MC 976

    CAS:
    <p>(24S)-MC 976 is a derivative of Vitamin D3.</p>
    Fórmula:C27H42O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:414.62
  • N-Desmethyl imatinib mesylate

    CAS:
    <p>Norimatinib mesylate, N-Desmethyl imatinib metabolite, inhibits v-Abl, c-Kit, PDGFR.</p>
    Fórmula:C29H33N7O4S
    Cor e Forma:Solid
    Peso molecular:575.68
  • Sarcophine

    CAS:
    <p>Sarcophine is a natural cembranoid from the Red Sea soft coral Sarcophyton glaucum.</p>
    Fórmula:C20H28O3
    Cor e Forma:Solid
    Peso molecular:316.441
  • GGACK hydrochloride


    <p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>
    Fórmula:C14H26Cl2N6O5
    Cor e Forma:Solid
    Peso molecular:428.13417
  • FXIIa-IN-1 HCl

    CAS:
    <p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>
    Fórmula:C21H17ClN2O6
    Pureza:99.61%
    Cor e Forma:Soild
    Peso molecular:428.82
  • DSPE-PEG1000-THRPPMWSPVWP


    <p>DSPE-PEG1000-THRPPMWSPVWP is a PEG compound composed of DSPE and the transferrin receptor (TfR) peptide. The THRPPMWSPVWP peptide binds to TfR and is subsequently internalized into cells expressing TfR.</p>
    Cor e Forma:Odour Solid
  • Methiocarb

    CAS:
    <p>Methiocarb is a carbamate insecticide acting as a reversible AChE or ChE inhibitor, inducing oxidative stress in rats.</p>
    Fórmula:C11H15NO2S
    Pureza:98.49%
    Cor e Forma:Colorless Crystals Immobilizing Agent For Birds Acaricide And Molluscicide (Epa 1998)
    Peso molecular:225.31
  • Diadenosine pentaphosphate pentasodium

    CAS:
    <p>Diadenosine pentaphosphate pentasodium, an endogenous purine from platelets and various cells, has vasoactive properties.</p>
    Fórmula:C20H24N10Na5O22P5
    Cor e Forma:Solid
    Peso molecular:1026.28
  • (±)20-HDHA

    CAS:
    <p>(±)20-HDHA is an autoxidation product and is a racemic mixture of Docosahexaenoic acid (DHA).</p>
    Fórmula:C22H32O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:344.49
  • Isodihydroauroglaucin

    CAS:
    <p>Isodihydroauroglaucin is a useful organic compound for research related to life sciences. The catalog number is T124274 and the CAS number is 74886-31-0.</p>
    Fórmula:C19H24O3
    Cor e Forma:Solid
    Peso molecular:300.398
  • Adenosine 5'-succinate

    CAS:
    <p>Adenosine 5'-succinate, similar to AMP, inhibits taste receptors activated by Denatonium.</p>
    Fórmula:C14H17N5O7
    Cor e Forma:Solid
    Peso molecular:367.318
  • Tetrachlorocatechol

    CAS:
    <p>Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol.</p>
    Fórmula:C6H2Cl4O2
    Pureza:96.68%
    Cor e Forma:Solid
    Peso molecular:247.89
  • Carbolactone

    CAS:
    <p>Carbolactone is a biologically active metabolite from fungi [1] .</p>
    Fórmula:C24H36O3
    Cor e Forma:Solid
    Peso molecular:372.54
  • Aminopeptidase N inhibitor 2


    <p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>
    Fórmula:C12H16F2N2O4S
    Cor e Forma:Solid
    Peso molecular:322.07988
  • α-Glucosidase-IN-22

    CAS:
    <p>α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM).</p>
    Fórmula:C14H11N3O2S
    Pureza:99.66%
    Cor e Forma:Soild
    Peso molecular:285.32
  • 5(S)​-​HPETE

    CAS:
    <p>5(S)-HpETE is a PUFA made by 5-LO from arachidonic acid, metabolized into LTA4, a key leukotriene precursor.</p>
    Fórmula:C20H32O4
    Cor e Forma:Solid
    Peso molecular:336.472
  • 3-Oxo-7-hydroxychol-4-enoic acid

    CAS:
    <p>3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.</p>
    Fórmula:C24H36O4
    Cor e Forma:Solid
    Peso molecular:388.54
  • Malate dehydrogenase

    CAS:
    <p>Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .</p>
    Cor e Forma:Solid
  • Heptanoyl-L-carnitine (chloride)

    CAS:
    <p>Heptanoyl-L-carnitine is a medium-chain acylcarnitine and derivative of L-carnitine .</p>
    Fórmula:C14H28ClNO4
    Cor e Forma:Solid
    Peso molecular:309.83
  • H-Gly-Pro-Gly-NH2

    CAS:
    <p>H-Gly-Pro-Gly-NH2, a tripeptide, inhibits HIV-1 and HIV-2 replication (EC50: 35µM, 30µM) by blocking capsid formation.</p>
    Fórmula:C9H16N4O3
    Cor e Forma:Solid
    Peso molecular:228.25
  • O-Desisobutyl-O-n-propyl Febuxostat

    CAS:
    <p>O-Desisobutyl-O-n-propyl Febuxostat, an xanthine oxidase inhibitor.</p>
    Fórmula:C15H14N2O3S
    Cor e Forma:Solid
    Peso molecular:302.35
  • Mycophenolate mofetil hydrochloride

    CAS:
    <p>Mycophenolate Mofetil: Non-competitive, selective inhibitor of IMP dehydrogenase I/II, IC50: 39/27 nM.</p>
    Fórmula:C23H32ClNO7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:469.96
  • N-Demethylerythromycin A

    CAS:
    <p>N-Demethylerythromycin A, a metabolite of erythromycin from S. erythreus, may contaminate its preparations.</p>
    Fórmula:C36H65NO13
    Cor e Forma:Solid
    Peso molecular:719.9
  • Ascorbate oxidase

    CAS:
    <p>Ascorbate oxidase, a REDOX enzyme, catalyzes ascorbic acid and oxygen to dehydroascorbic acid, regulating the extracellular matrix.</p>
    Cor e Forma:Solid
  • Equilenin

    CAS:
    <p>Equilenin (E 400) is a natural estrogen that is an endocrine disruptor and has been used in breast cancer research.</p>
    Fórmula:C18H18O2
    Pureza:99.4%
    Cor e Forma:Solid
    Peso molecular:266.33
  • HIV-1 inhibitor-58


    <p>HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type</p>
    Fórmula:C26H24N6O2
    Cor e Forma:Solid
    Peso molecular:452.51
  • Defensin HNP-2 human

    CAS:
    <p>Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.</p>
    Fórmula:C147H223N43O37S6
    Cor e Forma:Solid
    Peso molecular:3377.03
  • PKCζ/ι pseudosubstrate inhibitor

    CAS:
    <p>PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction of</p>
    Fórmula:C76H128N30O16
    Cor e Forma:Solid
    Peso molecular:1718.02
  • H-Ile-Pro-Pro-OH acetate


    H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.
    Fórmula:C18H31N3O6
    Pureza:97.15%
    Cor e Forma:Solid
    Peso molecular:385.46
  • Tanshinone IIA anhydride

    CAS:
    <p>Tanshinone IIA anhydride: irreversible inhibitor for human CE1 (Ki=1.9 nM) and hiCE (Ki=1.4 nM).</p>
    Fórmula:C19H18O4
    Cor e Forma:Solid
    Peso molecular:310.34
  • ABC34

    CAS:
    <p>ABC34, an inactive JJH260 control, poorly inhibits AIG1 enzyme at IC50 &gt;25 μM; potently blocks off-target hydrolases ABHD6 and PPT1.</p>
    Fórmula:C31H33N5O6
    Cor e Forma:Solid
    Peso molecular:571.634
  • Ppack trifluoroacetate

    CAS:
    <p>Ppack trifluoroacetate: Peptide, inhibits thrombin, prevents clotting (Ki: 0.24 nM), used in anticoagulation &amp; thrombin research.</p>
    Fórmula:C23H32ClF3N6O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:564.99
  • CooP

    CAS:
    <p>CooP is a nonapeptide targeting glioblastoma. It binds to FABP3 for chemotherapy delivery.</p>
    Fórmula:C32H57N9O11S
    Cor e Forma:Solid
    Peso molecular:775.91
  • Axl-IN-16


    <p>Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptor</p>
    Fórmula:C14H19ClO8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:350.75
  • FABP4-IN-4


    <p>FABP4-IN-4 (Compound 30) is an orally effective inhibitor of FABP, with an IC50 value of 1.18 μM against FABP1. In a mouse model of diet-induced obesity, FABP4-IN-4 improves glucose tolerance, reduces levels of blood sugar, lipids, and liver inflammation markers, alleviates hepatic steatosis, and exhibits anti-inflammatory activity.</p>
    Cor e Forma:Odour Solid
  • Mebeverine acid

    CAS:
    <p>Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.</p>
    Fórmula:C16H25NO3
    Pureza:99.66%
    Cor e Forma:Solid
    Peso molecular:279.37
  • DSPE-PEG2000-THRPPMWSPVWP


    <p>DSPE-PEG2000-THRPPMWSPVWP is a PEG compound composed of DSPE and transferrin receptor (TfR) peptide. The sequence THRPPMWSPVWP binds to TfR and is subsequently internalized into cells expressing TfR.</p>
    Cor e Forma:Odour Solid