Metabolismo
Os inibidores do metabolismo são compostos que interferem nas vias metabólicas, alterando a produção e utilização de energia dentro das células. Esses inibidores são usados para estudar a regulação do metabolismo, o papel das vias metabólicas em doenças como o câncer e o diabetes, e para desenvolver novas estratégias terapêuticas. Os inibidores do metabolismo podem direcionar várias enzimas e processos envolvidos na glicólise, na oxidação de ácidos graxos e em outras funções metabólicas. Na CymitQuimica, oferecemos uma ampla gama de inibidores do metabolismo de alta qualidade para apoiar sua pesquisa em bioquímica, distúrbios metabólicos e desenvolvimento de medicamentos.
Subcategorias de "Metabolismo"
- AhR(42 produtos)
- Aminopeptidase(76 produtos)
- CETP(20 produtos)
- Anidrase carbónica(196 produtos)
- Caseína quinase(138 produtos)
- DHFR(32 produtos)
- Descarboxilase(4 produtos)
- Desidrogenase(302 produtos)
- FAAH(66 produtos)
- FXR(62 produtos)
- Factor Xa(87 produtos)
- Sintase de Ácidos graxos(37 produtos)
- Ferroptose(226 produtos)
- GR(3 produtos)
- GSNOR(4 produtos)
- Glucoquinase(57 produtos)
- HIF/HIF Prolil-Hidroxilase(146 produtos)
- HMG-CoA Reductase(34 produtos)
- Hidroxilase(36 produtos)
- IDO(84 produtos)
- LDL(8 produtos)
- Lipase(107 produtos)
- Lipídio(61 produtos)
- Lipoxigenase(134 produtos)
- MAO(87 produtos)
- MPO(2 produtos)
- NAMPT(40 produtos)
- P450(6 produtos)
- PAI-1(26 produtos)
- PDE(170 produtos)
- PED(1 produtos)
- PKM(17 produtos)
- PPAR(170 produtos)
- Fosfolipase(84 produtos)
- ROR(47 produtos)
- Receptor de Retinóide(26 produtos)
- SGK(10 produtos)
- Tiorredoxina(12 produtos)
- Transferase(29 produtos)
- Tansportador(45 produtos)
- UGT(4 produtos)
- Inibidores de Xantina Oxidase (XO)(9 produtos)
Exibir 34 mais subcategorias
Foram encontrados 9245 produtos de "Metabolismo"
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GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Fórmula:C17H16ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:361.78CYP121A1-IN-1
CYP121A1-IN-1: Strong inhibitor for CYP121A1, hinders Mycobacterium tuberculosis growth (MIC 90 ~6.25 μM), reduces mycocyclosin synthesis.Fórmula:C22H20N4OCor e Forma:SolidPeso molecular:356.42LRAT-IN-1
CAS:LRAT-IN-1 (compound 1) is an inhibitor of lecithin retinol acyltransferase (LRAT) with an IC50 value of 21.1 μM. This compound works by inhibiting the esterification of retinol to form retinyl esters, thereby increasing the availability of retinol in the skin to deliver anti-aging benefits. LRAT-IN-1 is under investigation for its potential use as an anti-aging ingredient in cosmetics.Fórmula:C27H47N5O5S2Cor e Forma:SolidPeso molecular:585.82CYP2C1/CYP2C19-IN-2
CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Fórmula:C27H28N2O6SCor e Forma:SolidPeso molecular:508.59(E)-10-Hydroxynortriptyline maleate
CAS:(E)-10-Hydroxy Nortriptyline maleate, a derivative of antidepressant Nortriptyline, eases depression symptoms.Fórmula:C23H25NO5Pureza:98%Cor e Forma:SolidPeso molecular:395.455PF-00489791
CAS:PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.Fórmula:C20H28N8O4SPureza:99.97%Cor e Forma:SolidPeso molecular:476.55PLAP-IN-1
CAS:PLAP-IN-1: Potent, selective inhibitor of PLAP, IC50 of 32 nM; doesn't notably inhibit TNAP.Fórmula:C25H21Cl2N3O5Cor e Forma:SoildPeso molecular:514.36Epoxykynin
CAS:Epoxykynin is a potent soluble epoxide hydrolase (sEH) inhibitor [1].Fórmula:C19H20BrF3N2O2Cor e Forma:SolidPeso molecular:445.27PTP1B-IN-3 diammonium
PTP1B-IN-3 diammonium, an oral enzyme inhibitor, has potent antidiabetic and anticancer effects, with a 120 nM IC50.Fórmula:C12H13BrF2N3O3PCor e Forma:SolidPeso molecular:396.12FAAH/MAGL-IN-1
FAAH/MAGL-IN-1 (SIH 3) inhibits FAAH & MAGL with IC50 of 31 & 29 nM, useful in neuropathic pain research.Fórmula:C15H9Cl2N3O3Cor e Forma:SolidPeso molecular:350.16LTA4H-IN-3
CAS:LTA4H-IN-3 (compound 9) functions as an inhibitor of LTA4H, demonstrating an IC50 of 28 nM [1].Fórmula:C17H15ClN4O3Cor e Forma:SolidPeso molecular:358.78BAY-179
CAS:BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.Fórmula:C23H21N5OSPureza:98.29%Cor e Forma:SolidPeso molecular:415.51hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].Fórmula:C9H13N3O4SCor e Forma:SolidPeso molecular:259.287α,24(S)-Dihydroxycholesterol
CAS:7α,24(S)-Dihydroxycholesterol ((3β,7α,24S)-Cholest-5-ene-3,7,24-triol) acts as a ligand for liver X receptors (LXR), specifically binding to the ligand-binding domains of LXRα and LXRβ. This compound is synthesized through the E-α,β-unsaturated ketone process, starting with arsindole and J-secondary-butyl dimethylsiloxy-bis-positive-5-cholestenal as the initial materials. It undergoes a series of transformations to produce 7α,24(S)-dihydroxycholesterol.Fórmula:C27H46O3Cor e Forma:SolidPeso molecular:418.65MolPort-010-778-422
CAS:MolPort-010-778-422 is a high-affinity inhibitor targeting the ACE2 receptor of the SARS-CoV-2 virus. It demonstrates remarkable antiviral activity with an IC50 of 8.9 nM and holds promise for use in studies related to SARS-CoV-2.Fórmula:C20H26N2O3S2Cor e Forma:SolidPeso molecular:406.563-Ferrocenylpropionic anhydride
CAS:3-Ferrocenylpropionic anhydride is extensively used in compound synthesis, serving as an intermediary for producing various bioactive compounds. Additionally, by modulating specific enzyme activities, 3-Ferrocenylpropionic anhydride has demonstrated potential anti-tumor properties.Fórmula:C26H26Fe2O3Cor e Forma:SolidPeso molecular:498.17UGT1A1-IN-1
CAS:UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].Fórmula:C22H19NO3Cor e Forma:SolidPeso molecular:345.39ABHD antagonist 1
CAS:ABHD antagonist 1 is an inhibitor of ABHD6 (α/β-Hydrolase domain containing 6), involved in modulating biochemical pathways affected by ABHD6, thereby influencing cell function and inflammatory responses. This compound is applicable for research in fields such as pain, neurological disorders, inflammatory diseases, autoimmune diseases, metabolic disorders, and cancer.Fórmula:C19H20BrN3O3SCor e Forma:SolidPeso molecular:450.359(Z),12(E)-Octadecadienoic Acid
CAS:9(Z),12(E)-Octadecadienoic Acid (C18:2(9E,12Z); C18:2 n-6), an isomer of linoleic acid, is a type of ω-6 polyunsaturated fatty acid containing a trans double bond at the C9 position. It is identified as a minor component in milk fat and partially hydrogenated vegetable oils. The concentration of 9(Z),12(E)-Octadecadienoic Acid in rabbit meat increases following supplementation with heated sunflower seed oil, α-tocopherol acetate, and zinc.Fórmula:C18H32O2Peso molecular:280.45Osunprotafib hydrochloride
CAS:Osunprotafib (ABBV-CLS-484) hydrochloride is an orally active, selective inhibitor targeting the active sites of PTPN1 (IC50: 2.5 nM) and PTPN2 (IC50: 1.8 nM). It shows 6-8 times weaker activity towards PTPN9 and no detectable activity against SHP-1 or SHP-2. This compound enhances the sensitivity of human cancer cell lines to IFNγ. By boosting JAK-STAT signaling and reducing T cell dysfunction, Osunprotafib hydrochloride exhibits potent antitumor immunity.Fórmula:C17H25ClFN3O4SCor e Forma:SolidPeso molecular:421.92
