Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Formula:C23H21ClN2O5Purity:98% - 99.96%Color and Shape:SolidMolecular weight:440.88Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Formula:C45H50ClN7O7SPurity:98.00% - 99.97%Color and Shape:SolidMolecular weight:868.44Limonin
CAS:<p>Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.</p>Formula:C26H30O8Purity:99.65% - 99.66%Color and Shape:White To Slightly Off White PowderMolecular weight:470.51(-)-Huperzine A
CAS:<p>(-)-Huperzine A: Lycopodium alkaloid, AChE inhibitor, treats Alzheimer's in China.</p>Formula:C15H18N2OPurity:99.19% - >99.99%Color and Shape:White To Slight White Crystaline PowderMolecular weight:242.32WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2KYP-2047
CAS:<p>KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.</p>Formula:C20H25N3O2Purity:99.71%Color and Shape:SolidMolecular weight:339.43Glyphosate
CAS:<p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>Formula:C3H8NO5PPurity:99.12% - 99.91%Color and Shape:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Molecular weight:169.07S63845
CAS:<p>S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.</p>Formula:C39H37ClF4N6O6SPurity:97.7% - ≥98%Color and Shape:SolidMolecular weight:829.26SC99
CAS:<p>SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.</p>Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Mdivi-1
CAS:<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Formula:C15H10Cl2N2O2SPurity:96.57% - 99.23%Color and Shape:SolidMolecular weight:353.22Quinidine
CAS:<p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42Prosapogenin A
CAS:<p>Prosapogenin A (Progenin III) has anticancer activity.</p>Formula:C39H62O12Purity:99.60% - 99.75%Color and Shape:SolidMolecular weight:722.9T-1101 tosylate
CAS:<p>T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.</p>Formula:C31H31N5O6S3Purity:98.1%Color and Shape:SolidMolecular weight:665.8PYR-41
CAS:<p>PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.</p>Formula:C17H13N3O7Purity:98.25%Color and Shape:SolidMolecular weight:371.3Amuvatinib
CAS:<p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>Formula:C23H21N5O3SPurity:99.38% - >99.99%Color and Shape:SolidMolecular weight:447.51DAPK Substrate Peptide acetate
<p>DAPK Substrate Peptide acetate is a death-associated protein kinase (DAPK, Km = 9 μM) peptide substrate.</p>Formula:C70H115N25O17Purity:98.12%Color and Shape:SolidMolecular weight:1578.82PHA-665752
CAS:<p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.</p>Formula:C32H34Cl2N4O4SPurity:97.05% - 98.82%Color and Shape:SolidMolecular weight:641.61Notopterol
CAS:<p>1. Notopterol induces apoptosis and inhibits cell cycle-specific.</p>Formula:C21H22O5Purity:97.57% - 99.82%Color and Shape:SolidMolecular weight:354.4NSC348884
CAS:<p>NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).</p>Formula:C38H40N10Purity:98.69% - 99.91%Color and Shape:SolidMolecular weight:636.79Berbamine dihydrochloride
CAS:<p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>Formula:C37H42Cl2N2O6Purity:95% - 99.99%Color and Shape:SolidMolecular weight:681.65SP-141
CAS:<p>SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.</p>Formula:C22H16N2OPurity:98.01%Color and Shape:SolidMolecular weight:324.38BIO-acetoxime
CAS:<p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>Formula:C18H12BrN3O3Purity:97.15%Color and Shape:SolidMolecular weight:398.21Domatinostat tosylate
CAS:<p>4SC-202 is a class I HDAC inhibitor targeting HDAC1/2/3; shows activity against LSD1. IC50: HDAC1 (1.20 μM), HDAC2 (1.12 μM), HDAC3 (0.57 μM).</p>Formula:C30H29N5O6S2Purity:97.35% - >99.99%Color and Shape:Solid PowderMolecular weight:619.71LJH685
CAS:<p>LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).</p>Formula:C22H21F2N3OPurity:99.13% - 99.78%Color and Shape:SolidMolecular weight:381.42Phenoxodiol
CAS:<p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>Formula:C15H12O3Purity:98.07%Color and Shape:SolidMolecular weight:240.25ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Formula:C22H29ClN4O3Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:432.94Carvacrol
CAS:<p>1.</p>Formula:C10H14OPurity:99.05%Color and Shape:Needles LiquidMolecular weight:150.22MFCD01917484
CAS:<p>MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.</p>Formula:C14H15NO3SPurity:98.09%Color and Shape:SolidMolecular weight:277.34BAY 11-7082
CAS:<p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>Formula:C10H9NO2SPurity:98% - 99.92%Color and Shape:SolidMolecular weight:207.25(6R)-FR054
CAS:<p>(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.</p>Formula:C14H19NO8Purity:99.61%Color and Shape:SolidMolecular weight:329.3PD173074
CAS:<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Formula:C28H41N7O3Purity:98.15% - 98.21%Color and Shape:Yellow SolidMolecular weight:523.67Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Formula:C9H11F2N3O4·HClPurity:99.28% - 99.98%Color and Shape:White Crystalline Granular OdorlessMolecular weight:299.66AEE788
CAS:<p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>Formula:C27H32N6Purity:98% - >99.99%Color and Shape:SolidMolecular weight:440.5818α-Glycyrrhetinic acid
CAS:<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Formula:C30H46O4Purity:98.54% - 99.68%Color and Shape:SolidMolecular weight:470.68Antineoplaston A10
CAS:<p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Valepotriate
CAS:<p>Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.</p>Formula:C22H30O8Purity:97.29% - 99.90%Color and Shape:SolidMolecular weight:422.47(E)-Flavokawain A
CAS:<p>(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway.</p>Formula:C18H18O5Purity:98% - 99.75%Color and Shape:SolidMolecular weight:314.332Atractylenolide III
CAS:<p>Atractylenolide III could treat cognitive issues and lung cancer by modulating apoptosis factors.</p>Formula:C15H20O3Purity:99.53% - 99.82%Color and Shape:SolidMolecular weight:248.32Oleuropein
CAS:<p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>Formula:C25H32O13Purity:98% - 99.95%Color and Shape:Brown PowderMolecular weight:540.51Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Formula:C29H34N6O4S2Purity:97.67% - 98.44%Color and Shape:SolidMolecular weight:594.75Neogambogic acid
CAS:<p>Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect.</p>Formula:C38H46O9Purity:97.74% - 99.38%Color and Shape:SolidMolecular weight:646.77Indirubin
CAS:<p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>Formula:C16H10N2O2Purity:97.21% - 99.74%Color and Shape:Reddish-Violet PowderMolecular weight:262.26MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formula:C26H41N3O5Purity:95% - 99.99%Color and Shape:White To Off-White PowderMolecular weight:475.62GSK4112
CAS:<p>GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.</p>Formula:C18H21ClN2O4SPurity:99.69%Color and Shape:SolidMolecular weight:396.89CCF642
CAS:<p>CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.</p>Formula:C15H10N2O4S3Purity:97.12% - 98.82%Color and Shape:SolidMolecular weight:378.45Nelarabine
CAS:<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Formula:C11H15N5O5Purity:98.10% - 99.6%Color and Shape:White SolidMolecular weight:297.27Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.44Hispidol
CAS:<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Formula:C15H10O4Purity:97.86% - 98.45%Color and Shape:SolidMolecular weight:254.24Lupeol
CAS:<p>Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.</p>Formula:C30H50OPurity:98% - 99.96%Color and Shape:Needles From Alcohol Acetone White PowderMolecular weight:426.724-Methyldaphnetin
CAS:<p>4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.</p>Formula:C10H8O4Purity:99.73%Color and Shape:SolidMolecular weight:192.17Brevilin A
CAS:<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Formula:C20H26O5Purity:99.97% - >99.99%Color and Shape:SolidMolecular weight:346.42Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formula:C20H20N8Na2O5Purity:99.77% - 99.96%Color and Shape:SolidMolecular weight:498.4PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Formula:C18H39NO3Purity:99.81%Color and Shape:SolidMolecular weight:317.51Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59Picroside II
CAS:<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Formula:C23H28O13Purity:98% - 99.83%Color and Shape:SolidMolecular weight:512.46Desmethylanethol trithione
CAS:<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Formula:C9H6OS3Purity:98.05% - 98.41%Color and Shape:SolidMolecular weight:226.34Oncrasin-1
CAS:<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Formula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73ONC212
CAS:<p>ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.</p>Formula:C24H23F3N4OPurity:99.79%Color and Shape:SolidMolecular weight:440.46β-Ionone
CAS:<p>β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic</p>Formula:C13H20OPurity:98.52%Color and Shape:Colourless Liquid OilyMolecular weight:192.3Bioymifi
CAS:<p>Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.</p>Formula:C22H12BrN3O4SPurity:98% - 99.79%Color and Shape:SolidMolecular weight:494.32OTS514
CAS:<p>OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor.</p>Formula:C21H20N2O2SPurity:99.62%Color and Shape:SolidMolecular weight:364.46UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Formula:C25H37N5O2SPurity:97.052% - 99.72%Color and Shape:SolidMolecular weight:471.66Ibandronate sodium monohydrate
CAS:<p>Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.</p>Formula:C9H24NNaO8P2Purity:99.62%Color and Shape:White Crystalline PowderMolecular weight:359.23Obatoclax Mesylate
CAS:<p>Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and</p>Formula:C20H19N3O·CH4O3SPurity:99.58% - 99.88%Color and Shape:SolidMolecular weight:413.49CHR-6494 TFA
CAS:<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Formula:C18H17F3N6O2Purity:99.50%Color and Shape:SolidMolecular weight:406.36MPTP hydrochloride
CAS:<p>MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.</p>Formula:C12H16ClNPurity:96.35% - >99.99%Color and Shape:SolidMolecular weight:209.72Choline
CAS:<p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>Formula:C5H15NO2Purity:99.97% - ≥98%Color and Shape:LiquidMolecular weight:121.18Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Formula:C21H17Cl3N4OSPurity:97.25% - >99.99%Color and Shape:SolidMolecular weight:479.81Evocarpine
CAS:<p>Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.</p>Formula:C23H33NOPurity:99.77% - 99.819%Color and Shape:SolidMolecular weight:339.51PD0166285
CAS:<p>PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.</p>Formula:C26H27Cl2N5O2Purity:99.23%Color and Shape:SolidMolecular weight:512.43Bacopaside II
CAS:<p>Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.</p>Formula:C47H76O18Purity:98.14% - 99.86%Color and Shape:SolidMolecular weight:929.1Momordin Ic
CAS:<p>Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction</p>Formula:C41H64O13Purity:98% - 99.69%Color and Shape:SolidMolecular weight:764.94Acacetin
CAS:<p>Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant</p>Formula:C16H12O5Purity:96.26% - ≥95%Color and Shape:Pale-Yellow NeedlesMolecular weight:284.26MRS 2578
CAS:<p>MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.</p>Formula:C20H20N6S4Purity:97.58% - 99.73%Color and Shape:White SolidMolecular weight:472.67Neferine
CAS:<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.77PKR-IN-C16
CAS:<p>PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.</p>Formula:C13H8N4OSPurity:97.8%Color and Shape:SolidMolecular weight:268.29G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39OTS514 hydrochloride
CAS:<p>OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).</p>Formula:C21H20N2O2S·HClPurity:99.67% - 99.84%Color and Shape:SolidMolecular weight:400.92MK-886
CAS:<p>MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).</p>Formula:C27H34ClNO2SPurity:99.23% - 99.84%Color and Shape:SolidMolecular weight:472.08CASIN
CAS:<p>CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).</p>Formula:C20H22N2OPurity:98.18% - >99.99%Color and Shape:SolidMolecular weight:306.4NU 7026
CAS:<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Formula:C17H15NO3Purity:99.51% - >99.99%Color and Shape:SolidMolecular weight:281.31SKF-96365 hydrochloride
CAS:<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Formula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91NSC 66811
CAS:<p>NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.</p>Formula:C23H20N2OPurity:96.94%Color and Shape:SolidMolecular weight:340.42(S)-10-Hydroxycamptothecin
CAS:<p>(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.</p>Formula:C20H16N2O5Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:364.35AZD0156
CAS:<p>AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.</p>Formula:C26H31N5O3Purity:99.13% - 99.87%Color and Shape:SolidMolecular weight:461.56Ginsenoside Rg1
CAS:<p>Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).</p>Formula:C42H72O14Purity:99% - 99.74%Color and Shape:White Crystalline PowderMolecular weight:801.01Purvalanol A
CAS:<p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>Formula:C19H25ClN6OPurity:98.13% - 99.68%Color and Shape:PowderMolecular weight:388.89Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26BMS-202
CAS:<p>BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.</p>Formula:C25H29N3O3Purity:97.92% - 99.66%Color and Shape:SolidMolecular weight:419.52PU02
CAS:<p>PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C16H12N4SPurity:99.35%Color and Shape:SolidMolecular weight:292.36Apitolisib
CAS:<p>Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).</p>Formula:C23H30N8O3SPurity:98.28% - 99.64%Color and Shape:SolidMolecular weight:498.6SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Formula:C62H84N14O6Purity:98.53% - 99.92%Color and Shape:SolidMolecular weight:1121.42FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Formula:C22H30ClN3O3S2Purity:97.57% - 97.61%Color and Shape:SolidMolecular weight:484.07CID5721353
CAS:<p>CID5721353 disrupts BCL6/corepressor complexes, binds critical BTB groove site in vitro/vivo.</p>Formula:C15H9BrN2O6S2Purity:98.90%Color and Shape:SolidMolecular weight:457.28Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Formula:C33H25F6N3O3Purity:99.75%Color and Shape:SolidMolecular weight:625.56Y-27632
CAS:<p>Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.</p>Formula:C14H21N3OPurity:99.53% - 99.87%Color and Shape:SolidMolecular weight:247.34Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Formula:C20H30N2O4Purity:97.06% - 98.33%Color and Shape:White To Off-White PowderMolecular weight:362.463-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Formula:C3H3BrO3Purity:95% - 99.644%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:166.96Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Formula:C24H30N6O2Purity:98.87%Color and Shape:SolidMolecular weight:434.53
