Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(116 products)
- CDK(547 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(46 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(180 products)
- Integrin(276 products)
- Kinesin(87 products)
- LIM Kinase(21 products)
- Microtubule Associated(273 products)
- PKC(127 products)
- PLK(25 products)
- ROCK(61 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(77 products)
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Found 3923 products of "Cell Cycle/Checkpoint"
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Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formula:C20H21N7O7·CaPurity:99.07% - ≥98%Color and Shape:White Crystalline PowderMolecular weight:511.55-Chloro-2'-deoxyuridine
CAS:5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog.Formula:C9H11ClN2O5Purity:99.54%Color and Shape:SolidMolecular weight:262.65Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Formula:C26H32ClN7O4SColor and Shape:SolidMolecular weight:574.09CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formula:C9H6N2O4Purity:98.27% - 98.98%Color and Shape:Brown PowderMolecular weight:206.15EG1
CAS:EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.Formula:C22H18N2O5Purity:97.48%Color and Shape:SolidMolecular weight:390.39Ref: TM-T27246
1mL*10mM (DMSO)33.00€2mg34.00€5mg54.00€10mg86.00€25mg130.00€50mg187.00€100mg260.00€200mg370.00€Fanotaprim
CAS:Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.Formula:C19H22N8OPurity:98.1%Color and Shape:SolidMolecular weight:378.43Ref: TM-T36692
1mg50.00€2mg71.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg170.00€25mg318.00€50mg442.00€100mg627.00€200mg845.00€Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Formula:C12H13FN4O5Color and Shape:SolidMolecular weight:312.257AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Ref: TM-T3068
2mg39.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg111.00€25mg231.00€50mg371.00€100mg595.00€200mg833.00€GDC-0575
CAS:GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).Formula:C16H20BrN5OPurity:≥95%Color and Shape:SolidMolecular weight:378.27N1-Methylpseudouridine
CAS:N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms byFormula:C10H14N2O6Purity:98.95% - 99.88%Color and Shape:SolidMolecular weight:258.23Fadraciclib
CAS:Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52Ref: TM-TQ0053
1mg42.00€2mg55.00€1mL*10mM (DMSO)87.00€5mg88.00€10mg145.00€25mg260.00€50mg414.00€100mg583.00€HA-100
CAS:HA-100 is an inhibitor of protein kinaseFormula:C13H15N3O2SPurity:99.44%Color and Shape:Pale Yellow Crystalline SolidMolecular weight:277.34TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormula:C22H23N5O8Purity:97.73%Color and Shape:SolidMolecular weight:485.45Ref: TM-T9010
1mg38.00€5mg92.00€1mL*10mM (DMSO)124.00€10mg128.00€25mg215.00€50mg304.00€100mg411.00€200mg570.00€BAY-1816032
CAS:BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.Formula:C27H24F2N6O4Purity:98.02% - 99.81%Color and Shape:SolidMolecular weight:534.51Ref: TM-T10467
1mg35.00€5mg80.00€1mL*10mM (DMSO)95.00€10mg119.00€25mg230.00€50mg339.00€100mg485.00€200mg665.00€MSC2530818
CAS:MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Formula:C18H17ClN4OPurity:98.93%Color and Shape:SolidMolecular weight:340.81Ref: TM-TQ0266
1mg63.00€5mg137.00€1mL*10mM (DMSO)150.00€10mg215.00€25mg462.00€50mg692.00€100mg964.00€Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.325-Fluorocytidine
CAS:5-Fluorocytidine with antiviral activityFormula:C9H12FN3O5Purity:99.23%Color and Shape:White PowderMolecular weight:261.21CRT0066854
CAS:CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.Formula:C24H25N5SColor and Shape:SolidMolecular weight:415.55Adefovir dipivoxil
CAS:Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity againstFormula:C20H32N5O8PPurity:98% - 99.80%Color and Shape:It Has Broad-Spectrum Antiviral ActivityMolecular weight:501.47SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Formula:C16H12F3N3SPurity:97.98% - >99.99%Color and Shape:SolidMolecular weight:335.35Talotrexin
CAS:Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.Formula:C27H27N9O6Color and Shape:SolidMolecular weight:573.56BTB-1
CAS:BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.Formula:C12H8ClNO4SPurity:99.71%Color and Shape:SolidMolecular weight:297.716-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Formula:C12H9BrN2OSPurity:≥95%Color and Shape:SolidMolecular weight:309.185-Fluoroorotic acid
CAS:5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Formula:C5H3FN2O4Purity:99.7% - >99.99%Color and Shape:White To Pale Yellow PowderMolecular weight:174.09IMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Formula:C25H29F2N5OPurity:98.48% - 99.52%Color and Shape:SolidMolecular weight:453.53Ref: TM-T9350
1mg137.00€2mg178.00€5mg268.00€1mL*10mM (DMSO)294.00€10mg444.00€25mg790.00€50mg1,063.00€XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55FUBP1-IN-1
CAS:FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.Formula:C19H14F3N3O2SPurity:99.7%Color and Shape:SolidMolecular weight:405.39Ref: TM-T11332
1mg72.00€1mL*10mM (DMSO)144.00€5mg160.00€10mg245.00€25mg406.00€50mg572.00€100mg772.00€200mg1,035.00€Palbociclib
CAS:Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.Formula:C24H29N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:447.53A-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Formula:C22H24Cl2N4OPurity:94.66%Color and Shape:SolidMolecular weight:431.36Ref: TM-T6139L
1mg81.00€5mg131.00€1mL*10mM (DMSO)161.00€10mg178.00€25mg318.00€50mg479.00€100mg692.00€Besifloxacin Hydrochloride
CAS:Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.Formula:C19H21ClFN3O3·HClPurity:99.20%Color and Shape:Pale Yellow SolidMolecular weight:430.3Ref: TM-T6406
5mg38.00€1mL*10mM (DMSO)52.00€10mg57.00€25mg97.00€50mg172.00€100mg319.00€200mg470.00€500mg750.00€roxifiban
CAS:Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.
Formula:C21H29N5O6Purity:98%Color and Shape:SolidMolecular weight:447.48CCG-222740
CAS:CCG-222740 is an inhibitor of Rho/MRTF pathwayFormula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Ref: TM-T7764
2mg39.00€5mg62.00€1mL*10mM (DMSO)66.00€10mg94.00€25mg172.00€50mg260.00€100mg371.00€200mg530.00€GSK-25
CAS:GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Formula:C24H16Cl2F2N6OPurity:98.59%Color and Shape:SolidMolecular weight:513.33Ref: TM-T4488
1mg44.00€2mg56.00€5mg87.00€1mL*10mM (DMSO)89.00€10mg111.00€25mg168.00€50mg258.00€100mg430.00€PNU112455A hydrochloride
CAS:PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.Formula:C10H12ClN5O2SPurity:98.58% - 99.22%Color and Shape:SolidMolecular weight:301.75Ref: TM-T8230
2mg44.00€5mg71.00€1mL*10mM (DMSO)79.00€10mg100.00€25mg172.00€50mg266.00€100mg434.00€500mg964.00€Eptifibatide acetate (148031-34-9 free base)
CAS:Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.Formula:C35H49N11O9S2·xC2H4O2Purity:99.7% - 99.87%Color and Shape:SolidMolecular weight:891.012-Chloropyrazine
CAS:2-Chloropyrazine is used in chemical industry.Formula:C4H3ClN2Purity:98.98% - 99.89%Color and Shape:Clear Colorless To Yellowish LiquidMolecular weight:114.53CB-6644
CAS:CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.Formula:C29H34ClFN4O5Purity:96.33% - 99.85%Color and Shape:SolidMolecular weight:573.06Ref: TM-T10693
1mg205.00€5mg416.00€1mL*10mM (DMSO)525.00€10mg533.00€25mg748.00€50mg973.00€100mg1,260.00€ML367
CAS:ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.Formula:C19H12F2N4Purity:99.39%Color and Shape:SolidMolecular weight:334.326-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).Formula:C8H7BrO3Purity:99.82%Color and Shape:SolidMolecular weight:231.04APTO-253 HCl
CAS:APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.Formula:C22H15ClFN5Color and Shape:SolidMolecular weight:403.84RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purity:99.63% - 99.86%Color and Shape:SolidMolecular weight:433.28Ref: TM-T2628
1mg70.00€2mg92.00€5mg152.00€1mL*10mM (DMSO)166.00€10mg266.00€25mg413.00€50mg605.00€100mg863.00€Ribociclib succinate hydrate
CAS:Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).Formula:C27H38N8O6Purity:98%Color and Shape:SolidMolecular weight:570.651VPC-80051 racemate
CAS:VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.Formula:C16H13F2N3OPurity:97.36%Color and Shape:SolidMolecular weight:301.29C/EBPα inducer 1
CAS:C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation viaFormula:C20H12FN3O4Purity:98.99%Color and Shape:SolidMolecular weight:377.33MK-8745
CAS:MK-8745 is a potent and selective Aurora A inhibitor.Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91TC-E 5003
CAS:TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.Formula:C16H14Cl2N2O4SPurity:97.01%Color and Shape:SolidMolecular weight:401.26CAN508
CAS:CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.Formula:C9H10N6OPurity:98.65%Color and Shape:SolidMolecular weight:218.22TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52NU6027
CAS:NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-Formula:C11H17N5O2Purity:98.36%Color and Shape:SolidMolecular weight:251.29M2I-1
CAS:M2I-1 inhibits Mad2 binding to Cdc20, disrupting SAC-related PPI and Mad2 dynamics, blocks Mad2-F-Mbp1 in FP assays.Formula:C19H24N4O4SPurity:99.02% - >99.99%Color and Shape:SolidMolecular weight:404.48Poloxin
CAS:Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).Formula:C18H19NO3Purity:99.19%Color and Shape:SolidMolecular weight:297.35Antitumor agent-152
CAS:Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.Formula:C17H19N5O2S2Purity:95.00%Color and Shape:SolidMolecular weight:389.5Ref: TM-T50079
1mg85.00€5mg170.00€1mL*10mM (DMSO)185.00€10mg253.00€25mg414.00€50mg583.00€100mg783.00€200mg1,054.00€Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formula:C21H22NO4Purity:96.28% - 99.49%Color and Shape:SolidMolecular weight:352.4Preq1-Dihydrochloride
CAS:Preq1-Dihydrochloride, a queuosine pathway intermediate, binds strongly to PreQ1 riboswitch aptamer, suppressing protein expression.Formula:C7H11Cl2N5OPurity:99.46%Color and Shape:SolidMolecular weight:252.1Myoseverin
CAS:Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.
Formula:C24H28N6O2Purity:99.25%Color and Shape:SolidMolecular weight:432.52PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48SPHINX
CAS:SPHINX is a new generation inhibitor of SPRK1Formula:C17H17F3N2O3Purity:99.29%Color and Shape:SolidMolecular weight:354.322-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi
CAS:2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.Formula:C6H6N4OPurity:99.21% - 99.42%Color and Shape:SolidMolecular weight:150.141,7-Diaminoheptane
CAS:1,7-Diaminoheptane, an aliphatic amine, is used in peptide synthesis and as a substrate, ligand, or reagent.Formula:C7H18N2Purity:99.97%Color and Shape:White To Light Yellow Crystalline ChunksMolecular weight:130.23Pipobroman
CAS:Pipobroman (Vercyte) is an alkylating anti-cancer drug effective in PV and ET with low toxicity and thrombosis risk.Formula:C10H16Br2N2O2Purity:97.08%Color and Shape:SolidMolecular weight:356.05BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Formula:C20H27N5O3Purity:99.85%Color and Shape:SolidMolecular weight:385.46Fasudil dihydrochloride
CAS:Fasudil dihydrochloride inhibits ROCK1/2, PKA, PKC, PKG, and acts as a Ca²⁺ channel blocker and vasodilator, supporting vascular, cardiovascular, and signaling research.Formula:C14H19Cl2N3O2SPurity:99.86%Color and Shape:SolidMolecular weight:364.29AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Formula:C24H32N6O3Purity:97.84% - >99.99%Color and Shape:SolidMolecular weight:452.55A-286982
CAS:A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55Ref: TM-T21781
1mg34.00€2mg48.00€5mg71.00€1mL*10mM (DMSO)77.00€10mg102.00€25mg200.00€50mg333.00€100mg495.00€9-Ethylguanine
CAS:9-Ethylguanine is a model nucleobase commonly used in the studies of DNA interactions with organometallic complexes.Formula:C7H9N5OPurity:98.6%Color and Shape:SolidMolecular weight:179.18CWHM-12
CAS:CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).Formula:C26H32BrN5O6Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:590.47Ref: TM-TQ0250
1mg40.00€2mg52.00€5mg88.00€1mL*10mM (DMSO)96.00€10mg126.00€25mg221.00€50mg369.00€100mg550.00€Spermine tetrahydrochloride
CAS:Spermine tetrahydrochloride, a polyamine in all eukaryotic cells, protects DNA from free radicals.Formula:C10H26N4·4HClPurity:99.75% - 99.82%Color and Shape:SolidMolecular weight:348.18GJ103 sodium salt
CAS:GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, aiding molecular movement.Formula:C16H13N4NaO3SPurity:99.70% - 99.91%Color and Shape:SolidMolecular weight:364.36Sovilnesib
CAS:Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.Formula:C26H34F2N6O4SPurity:99.57%Color and Shape:SolidMolecular weight:564.65Ref: TM-T39994
1mg96.00€5mg235.00€1mL*10mM (DMSO)259.00€10mg376.00€25mg630.00€50mg898.00€100mg1,216.00€Gadodiamide
CAS:Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.Formula:C16H26GdN5O8Purity:99.86% - 99.93%Color and Shape:SolidMolecular weight:573.66GS-441524 HCl
CAS:GS-441524: Inhibits FIP virus, EC50 at 0.78 μM, precursor to active triphosphate, non-toxic up to 100 μM, works at ≥1 μM, metabolite of Remdesivir.Formula:C12H14ClN5O4Color and Shape:SolidMolecular weight:327.722,2'-Anhydrouridine
CAS:2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.Formula:C9H10N2O5Purity:98.45%Color and Shape:SolidMolecular weight:226.19Bohemine
CAS:Bohemine is a cyclin-dependent kinase inhibitor.Formula:C18H24N6OPurity:99.09% - 99.53%Color and Shape:SolidMolecular weight:340.42Nemorubicin HCL
CAS:Nemorubicin HCL, a PNU152243A salt, acts on resistant tumors via topoisomerase I inhibition and targets NER pathway upregulated cells.Formula:C32H38ClNO13Color and Shape:SolidMolecular weight:680.1PRT4165
CAS:PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.Formula:C15H9NO2Purity:98.91% - 99.6%Color and Shape:SolidMolecular weight:235.24Ref: TM-T3110
5mg43.00€10mg49.00€1mL*10mM (DMSO)50.00€25mg88.00€50mg112.00€100mg182.00€200mg254.00€500mg427.00€KIRA6
CAS:KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.
Formula:C28H25F3N6OPurity:97.91%Color and Shape:SolidMolecular weight:518.53M2N12
CAS:M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formula:C20H16ClN5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.83Ref: TM-T11929
1mg84.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg447.00€50mg670.00€100mg982.00€N2-Methylguanosine
CAS:N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's
Formula:C11H15N5O5Purity:97.77%Color and Shape:SolidMolecular weight:297.27Triciribine
CAS:Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Formula:C13H16N6O4Purity:99.01% - 99.87%Color and Shape:SolidMolecular weight:320.3Ref: TM-T6065
1mg38.00€2mg49.00€5mg80.00€1mL*10mM (DMSO)88.00€10mg116.00€25mg207.00€50mg329.00€100mg512.00€200mg727.00€Rg3039
CAS:Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy (SMA). RG3039 improves motor function in SMA mice.Formula:C21H23Cl2N5OPurity:98.24% - 99.58%Color and Shape:SolidMolecular weight:432.35ML-7 hydrochloride
CAS:ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM);Formula:C15H18ClIN2O2SPurity:99% - 99.26%Color and Shape:White PowderMolecular weight:452.74Ref: TM-T3050
2mg34.00€5mg47.00€1mL*10mM (DMSO)52.00€10mg71.00€25mg141.00€50mg230.00€100mg334.00€200mg434.00€Hu7691
CAS:Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Formula:C22H22ClF3N4OPurity:99.81%Color and Shape:SolidMolecular weight:450.88Ganciclovir sodium
CAS:Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formula:C9H13N5NaO4Purity:99.93%Color and Shape:SolidMolecular weight:278.227BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formula:C41H44N4O10SPurity:98.11%Color and Shape:SolidMolecular weight:784.87MTOB
CAS:MTOB, a CtBP substrate, inhibits CtBP-linked cancer activity in cells/mice and regulates TCF-4, affecting CSC proliferation.Formula:C5H7NaO3SPurity:98.23%Color and Shape:SolidMolecular weight:170.16VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formula:C24H20Cl2FN5O2Purity:98.92% - ≥98%Color and Shape:SolidMolecular weight:500.35Piritrexim isethionate
CAS:Piritrexim isethionate, a fat-soluble DHFR inhibitor, shows efficacy in metastatic urothelial cancer with a 5-day oral regimen.Formula:C19H25N5O6SColor and Shape:SolidMolecular weight:451.49HA-100 hydrochloride
CAS:HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.Formula:C13H16ClN3O2SColor and Shape:SolidMolecular weight:313.8Tirofiban hydrochloride monohydrate
CAS:Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Formula:C22H39ClN2O6SPurity:98.81% - >99.99%Color and Shape:White SolidMolecular weight:495.07GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:SolidMolecular weight:592.13Ref: TM-T2039
1mg49.00€5mg97.00€1mL*10mM (DMSO)136.00€10mg168.00€25mg283.00€50mg432.00€100mg605.00€200mg852.00€ON-013100
CAS:ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.44Ref: TM-T16391
1mg48.00€1mL*10mM (DMSO)60.00€5mg71.00€10mg100.00€25mg172.00€50mg268.00€100mg404.00€200mg570.00€Voruciclib
CAS:Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.Formula:C22H19ClF3NO5Purity:99.89% - 99.99%Color and Shape:SolidMolecular weight:469.84MLN8054 sodium
CAS:MLN8054 sodium is an Aurora A inhibitor.Formula:C25H14ClF2N4NaO2Color and Shape:SolidMolecular weight:498.84PHA-767491
CAS:PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.Formula:C12H11N3OPurity:99.49% - >99.99%Color and Shape:SolidMolecular weight:213.24Ref: TM-T6206
2mg34.00€5mg49.00€1mL*10mM (DMSO)50.00€10mg64.00€25mg92.00€50mg138.00€100mg197.00€200mg295.00€SBC-115337
CAS:SBC-115337 is a PCSK9 inhibitor.Formula:C29H19N3O4Purity:99.41%Color and Shape:SolidMolecular weight:473.48
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