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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3035 products of "Immunology and Inflammation"

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  • (E/Z)-IT-603

    CAS:
    <p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>
    Formula:C11H9BrN2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:329.17
  • Nodakenin

    CAS:
    <p>Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities.</p>
    Formula:C20H24O9
    Purity:95.46% - 98.93%
    Color and Shape:Solid
    Molecular weight:408.4
  • TLR7 agonist 2

    CAS:
    <p>TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).</p>
    Formula:C17H16N6O2
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:336.35
  • sphondin

    CAS:
    <p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>
    Formula:C12H8O4
    Purity:99.9% - ≥95%
    Color and Shape:Solid
    Molecular weight:216.19
  • IMM-H007

    CAS:
    <p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>
    Formula:C22H23N5O8
    Purity:97.73%
    Color and Shape:Solid
    Molecular weight:485.45
  • AEM1

    CAS:
    <p>AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.</p>
    Formula:C20H14FN3O2S
    Purity:98.37% - 99.88%
    Color and Shape:Solid
    Molecular weight:379.41
  • Eclitasertib

    CAS:
    <p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of &lt;1 µΜ).</p>
    Formula:C19H18N6O3
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:378.38
  • Ginsenoside Rb3

    CAS:
    <p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>
    Formula:C53H90O22
    Purity:98% - 99.98%
    Color and Shape:Solid
    Molecular weight:1079.27
  • RO2959 Hydrochloride

    CAS:
    <p>RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.</p>
    Formula:C21H20ClF2N5OS
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:463.93
  • Tizoxanide

    CAS:
    <p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>
    Formula:C10H7N3O4S
    Purity:98.89% - 99.28%
    Color and Shape:Solid
    Molecular weight:265.25
  • Ibuprofen Lysine

    CAS:
    <p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>
    Formula:C19H32N2O4
    Purity:99.26%
    Color and Shape:Coa
    Molecular weight:352.47
  • GSK-J4

    CAS:
    <p>GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.</p>
    Formula:C24H27N5O2
    Purity:98.24% - 99.98%
    Color and Shape:Solid
    Molecular weight:417.5
  • Cyclo(his-pro)

    CAS:
    <p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>
    Formula:C11H14N4O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:234.25
  • Nitroarginine

    CAS:
    <p>Nitroarginine (N'-Nitro-L-arginine) is a competitive inhibitor of nitric oxide synthase which causes the selective reduction of blood flow to tumor cells[1].</p>
    Formula:C6H13N5O4
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:219.2
  • Suplatast (Tosilate)

    CAS:
    <p>Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.</p>
    Formula:C23H33NO7S2
    Purity:99.34% - 99.65%
    Color and Shape:White Or Off-White Crystals
    Molecular weight:499.64
  • TR-14035

    CAS:
    <p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>
    Formula:C24H21Cl2NO5
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:474.33
  • CTX-0294885

    CAS:
    <p>CTX-0294885, a bisanilino pyrimidine, inhibits many kinases; used for Sepharose-based kinase capture.</p>
    Formula:C22H24ClN7O
    Purity:98.73% - ≥95%
    Color and Shape:Solid
    Molecular weight:437.93
  • CORM-3

    CAS:
    <p>CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.</p>
    Formula:C5H4ClNO5Ru
    Purity:98%
    Color and Shape:Solid
    Molecular weight:294.61
  • AS-2444697

    CAS:
    <p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>
    Formula:C19H21ClN6O4
    Purity:97.17%
    Color and Shape:Solid
    Molecular weight:432.86
  • CY-09

    CAS:
    <p>CY-09 is an NLRP3 inhibitor.</p>
    Formula:C19H12F3NO3S2
    Purity:99.25% - >99.99%
    Color and Shape:Solid
    Molecular weight:423.43
  • Ginsenoside Rg6

    CAS:
    <p>Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells</p>
    Formula:C42H70O12
    Purity:97.34%
    Color and Shape:Solid
    Molecular weight:767
  • Berbamine

    CAS:
    <p>Berbamine is a natural product extracted from Phellodendron amurense.</p>
    Formula:C37H40N2O6
    Purity:98.92% - 99.67%
    Color and Shape:White Crystal Powder
    Molecular weight:608.72
  • Dehydroevodiamine

    CAS:
    <p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>
    Formula:C19H15N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:301.34
  • Galloylpaeoniflorin

    CAS:
    <p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>
    Formula:C30H32O15
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:632.57
  • BX795

    CAS:
    <p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>
    Formula:C23H26IN7O2S
    Purity:98% - 99.57%
    Color and Shape:Solid
    Molecular weight:591.47
  • Demethyleneberberine

    CAS:
    <p>Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either</p>
    Formula:C19H18NO4
    Purity:98.08% - 99.18%
    Color and Shape:Solid
    Molecular weight:324.35
  • Danicopan

    CAS:
    <p>Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.</p>
    Formula:C26H23BrFN7O3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:580.41
  • BI-69A11

    CAS:
    <p>BI-69A11 is a dual AKT/NFkB inhibitor, increasing colon cancer cell sensitivity to mda-7/IL-24.</p>
    Formula:C25H16ClN3O2
    Purity:96.97%
    Color and Shape:Solid
    Molecular weight:425.87
  • 1-Caffeoylquinic acid

    CAS:
    <p>1-Caffeoylquinic acid: a lignin precursor with anti-influenza, antioxidant properties, and moderates post-meal glucose release.</p>
    Formula:C16H18O9
    Purity:99.15% - 99.16%
    Color and Shape:Solid
    Molecular weight:354.31
  • Stachydrine

    CAS:
    <p>Stachydrine, found in leonurus herb, aids blood flow, blocks NF-κB pathway, and indicates citrus intake.</p>
    Formula:C7H13NO2
    Purity:99.94% - ≥95%
    Color and Shape:Solid
    Molecular weight:143.18
  • Metyrosine

    CAS:
    <p>Metyrosine: antihypertensive, tyrosine hydroxylase inhibitor, controls COX-2, lowers blood pressure.</p>
    Formula:C10H13NO3
    Purity:98.68% - 99.72%
    Color and Shape:Solid
    Molecular weight:195.22
  • FICZ

    CAS:
    <p>FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).</p>
    Formula:C19H12N2O
    Purity:98.97%
    Color and Shape:Solid
    Molecular weight:284.31
  • anemarsaponin B

    CAS:
    <p>Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity</p>
    Formula:C45H74O18
    Purity:99.06% - 99.81%
    Color and Shape:Solid
    Molecular weight:903.06
  • 2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC

    CAS:
    <p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>
    Formula:C11H10N2OS
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:218.27
  • Vanillic Acid

    CAS:
    <p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>
    Formula:C8H8O4
    Purity:99.82%
    Color and Shape:White Odourless Crystals Or Powder
    Molecular weight:168.15
  • L-Alanyl-L-glutamine

    CAS:
    <p>L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.</p>
    Formula:C8H15N3O4
    Purity:99.71% - 99.97%
    Color and Shape:Solid
    Molecular weight:217.22
  • Berbamine dihydrochloride

    CAS:
    <p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>
    Formula:C37H42Cl2N2O6
    Purity:95% - 99.99%
    Color and Shape:Solid
    Molecular weight:681.65
  • Asperulosidic acid

    CAS:
    <p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>
    Formula:C18H24O12
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:432.38
  • YYA-021

    CAS:
    <p>YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.</p>
    Formula:C18H27N3O2
    Purity:97.17% - 99.87%
    Color and Shape:Solid
    Molecular weight:317.43
  • AF 12198 Acetate


    <p>AF 12198 Acetate is a novel low molecular weight antagonist of IL-1</p>
    Formula:C98H127N19O24
    Purity:95.27%
    Color and Shape:Solid
    Molecular weight:1955.17
  • IL-17A inhibitor 1

    CAS:
    <p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of &lt;9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>
    Formula:C24H27F5N8O4
    Purity:99.37% - 99.37%
    Color and Shape:Solid
    Molecular weight:586.51
  • TLR7/8 agonist 1

    CAS:
    <p>TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.</p>
    Formula:C22H25N5
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:359.47
  • SB-265610

    CAS:
    <p>SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.</p>
    Formula:C14H9BrN6O
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:357.16
  • Gypenoside L

    CAS:
    <p>Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.</p>
    Formula:C42H72O14
    Purity:99.42% - 99.65%
    Color and Shape:Solid
    Molecular weight:801.01
  • 4-IPP

    CAS:
    <p>4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF)</p>
    Formula:C10H7IN2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:282.08
  • Siponimod

    CAS:
    <p>Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; &gt;1000x selectivity over S1P2-4.</p>
    Formula:C29H35F3N2O3
    Purity:97.08% - 99.40%
    Color and Shape:Solid
    Molecular weight:516.59
  • Homo-PROTAC cereblon degrader 1

    CAS:
    <p>Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.</p>
    Formula:C32H32N6O10
    Purity:98.3%
    Color and Shape:Solid
    Molecular weight:660.63
  • Chlorthenoxazine

    CAS:
    <p>Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.</p>
    Formula:C10H10ClNO2
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:211.64
  • Iguratimod

    CAS:
    <p>Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits MIF (IC50: 6.81 μM).</p>
    Formula:C17H14N2O6S
    Purity:99.93%
    Color and Shape:White Powder
    Molecular weight:374.37
  • OPHIOPOGONIN D

    CAS:
    <p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>
    Formula:C44H70O16
    Purity:99.46% - ≥95%
    Color and Shape:Solid
    Molecular weight:855.02